CT and MR imaging of massive macronodular adrenocortical disease: a rare cause of autonomous primary adrenal hypercortisolism.


:We studied four patients with adrenocorticotropic hormone (ACTH)-independent hypercortisolism due to bilateral massive enlargement of the adrenal glands. The combined weight of the adrenal glands ranged from 69 to 149 g and the adrenal cortex was replaced in three of four patients by multiple nodules ranging from microscopic to 4 cm in diameter. One patient had massive diffuse enlargement. All patients had low or undetectable levels of serum ACTH, absence of petrosal sinus to peripheral gradients of ACTH in bilateral samples from the inferior petrosal sinuses before and after stimulation by corticotropin releasing hormone, and absence of an adenoma on MR imaging of the pituitary gland. The marked degree of adrenocortical enlargement and absence of ACTH dependency separates this massive macronodular disease from the more common ACTH-dependent macronodular hyperplasia encountered in older patients with pituitary-dependent Cushing disease. All patients required bilateral adrenalectomy to control hypercortisolism. We present the spectrum of nodular adrenal disease associated with hypercortisolism and a differential diagnosis based on morphologic criteria.


J Comput Assist Tomogr


Doppman JL,Nieman LK,Travis WD,Miller DL,Cutler GB Jr,Chrousos GP,Norton JA





Has Abstract


1991-09-01 00:00:00












  • Pedunculated bronchogenic cyst mimicking pleural lesion.

    abstract::We report a rare case of a bronchogenic cyst presenting as a pleural nodule. CT and MRI demonstrated a well circumscribed, homogeneous lesion located on the pleural surface apart from the mediastinum. It was proven to be a bronchogenic cyst localized between the parietal and visceral pleurae and connected with the med...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Yoshioka N,Minami M,Inoue Y,Kawauchi N,Nakajima J,Oka T,Yoshikawa K,Ohtomo K

    更新日期:2000-07-01 00:00:00

  • CT diagnosis of congenital intrapericardial masses.

    abstract::Prior to the development of CT, cardiac and pericardiac masses were evaluated by chest roentgenography, angiocardiography, and echocardiography. In most cases preoperative diagnosis of a specific entity was impossible. Preoperative CT diagnosis of an intrapericardial developmental mass becomes possible because of the ...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Moncada R,Baliga K,Moguillansky SJ,Subramanian R,Demos TC,Lozada C,Bianchi G,Ow EP

    更新日期:1985-01-01 00:00:00

  • Imaging of pancreas transplants: postoperative findings with clinical correlation.

    abstract::Pancreas transplantation has become more commonplace over the past several decades. Consequently, the radiological evaluation of patients with such transplants has also become more common. Radiologists must therefore be familiar with the normal imaging appearances of pancreas transplant grafts as well as a wide variet...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章,评审


    authors: Dillman JR,Elsayes KM,Bude RO,Platt JF,Francis IR

    更新日期:2009-07-01 00:00:00

  • Investigating demyelination in the brain in a canine model of globoid cell leukodystrophy (Krabbe disease) using magnetization transfer contrast: preliminary results.

    abstract:PURPOSE:This study was designed to examine the use of quantitative magnetization transfer imaging (MTI) in naturally occurring globoid cell leukodystrophy (GLD) in the Cairn terrier. METHOD:A model of GLD was established via a breeding colony, and a total of seven animals were studied with MTI, including two dogs with...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: McGowan JC,Haskins M,Wenger DA,Vite C

    更新日期:2000-03-01 00:00:00

  • Central dot sign on CT of liver cysts.

    abstract::The central dot sign on CT in Caroli disease has been described previously. We describe a patient with the central dot sign who had periductal cysts but did not have Caroli disease. ...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Herman TE,Siegel MJ

    更新日期:1990-11-01 00:00:00

  • Detection of renal ischemic lesions using Gd-DTPA enhanced turbo FLASH MRI: experimental and clinical results.

    abstract:PURPOSE:Our goal was to investigate the role of Gd-DTPA-enhanced dynamic MRI in the evaluation of renal ischemic lesions. METHOD:With a turbo FLASH sequence before and after injection of Gd-DTPA, nine foxhound dogs after 60-120 min of renal ischemia underwent MR examination. In addition, five patients with a tumor in ...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Vosshenrich R,Kallerhoff M,Gröne HJ,Fischer U,Funke M,Kopka L,Siebert G,Ringert RH,Grabbe E

    更新日期:1996-03-01 00:00:00

  • MR evaluation of chronic aortic dissection.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Pernes JM,Grenier P,Desbleds MT,de Brux JL

    更新日期:1987-11-01 00:00:00

  • Vascular encasement by pancreatic cancer: correlation of CT findings with surgical and pathologic results.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Nakayama Y,Yamashita Y,Kadota M,Takahashi M,Kanemitsu K,Hiraoka T,Hirota M,Ogawa M,Takeya M

    更新日期:2001-05-01 00:00:00

  • Oxygen-assisted breath-holding in computed tomography.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Sadatoh N,Hatabu H,Takahashi M,Imanaka K,Sano A

    更新日期:1987-07-01 00:00:00

  • Localization of scanning level in computed tomography of the spine.

    abstract::A simple method for identifying the scanning level in computed tomography (CT) of the spine is described. The method involves exposing a lead lattice grid on a conventional X-ray film and taking a conventional spine film with aluminum markers on the patient's back. The film showing the grid and the markers on the pati...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Dossetor RS,Veiga-Pires JA,Kaiser M

    更新日期:1979-04-01 00:00:00

  • Amyloidosis and lymphoproliferative disease in Sjögren syndrome: thin-section computed tomography findings and histopathologic comparisons.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Jeong YJ,Lee KS,Chung MP,Han J,Chung MJ,Kim KI,Seo JB,Franquet T

    更新日期:2004-11-01 00:00:00

  • Development of a novel computer-aided diagnosis system for automatic discrimination of malignant from benign solitary pulmonary nodules on thin-section dynamic computed tomography.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Mori K,Niki N,Kondo T,Kamiyama Y,Kodama T,Kawada Y,Moriyama N

    更新日期:2005-03-01 00:00:00

  • Rotating conventional gamma camera single-photon tomographic system: physical characterization.

    abstract::A whole-body single-photon emission computed tomography system has been evaluated in terms of its physical performance. It consists of a standard GE 400 T maxi camera rotating on a ring stand, coupled to an Informatek Simis 3 computer system. In its standard mode of operation, 64 or 128 successive views of 64 X 64 or ...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Soussaline FP,Todd-Popkropek AE,Zurowski S,Huffer E,Raynaud CE,Kellershohn CL

    更新日期:1981-08-01 00:00:00

  • Comparison of 320-row computed tomography coronary angiography with conventional angiography for the assessment of coronary artery disease with different atherosclerotic plaque characteristics.

    abstract:OBJECTIVE:The objective of this study was to compare the accuracy of 320-row computed tomography angiography (CTA) with conventional coronary angiography. METHODS:Two hundred seventy-four patients with coronary artery disease who received both invasive coronary angiography and 320-row CTA were included. Stenosis of 50...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Yang QH,Chen YJ,Liu QQ,Dong M,Wen L,Song X,Lv YJ,Gong YZ,Li XQ

    更新日期:2012-11-01 00:00:00

  • CT findings and mistopathology of intratumoral steatosis in focal nodular hyperplasia: case report and review of the literature.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章,评审


    authors: Stanley G,Jeffrey RB Jr,Feliz B

    更新日期:2002-09-01 00:00:00

  • External jugular vein thrombosis: CT demonstration.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Fishman EK,Gayler BW,Magid D,Siegelman SS

    更新日期:1985-05-01 00:00:00

  • Hemolymphangiomatosis of the spleen: imaging features.

    abstract::Hemolymphangiomatosis is an extremely rare entity that has never been described in the diffuse form. Its main pathologic feature is proliferation of lymphatic and vascular cells inducing interstitial and hematic lakes and then splenomegaly. We report a complete imaging study, including magnetic resonance (MR) imaging,...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Santoro L,Santini V,Lollo SD,Valeri A,Colagrande S

    更新日期:2005-11-01 00:00:00

  • Can Discrepancies Between Coronary Computed Tomography Angiography and Cardiac Catheterization in High-Risk Patients be Overcome With Consensus Reading?

    abstract:OBJECTIVE:To assess the incidence and cause of discrepancies between coronary computed tomography angiography (CTA) and catheterization in a high-risk, diverse, predominantly overweight inner-city population. METHODS:Ninety-two patients who underwent coronary CTA and catheterization on March 2007 to December 2012 were...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Steinberger S,Plodkowski AJ,Latson L,Levsky JM,Zalta B,Godelman A,Cohen HW,Haramati LB

    更新日期:2017-01-01 00:00:00

  • Pancreatic beta-cell tumors: MRI.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Pavone P,Mitchell DG,Leonetti F,Di Girolamo M,Cardone G,Catalano C,Tamburrano G,Passariello R

    更新日期:1993-05-01 00:00:00

  • CT findings in hepatic involvement by Echinococcus granulosus.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Pandolfo I,Blandino G,Scribano E,Longo M,Certo A,Chirico G

    更新日期:1984-10-01 00:00:00

  • Assessment of shape variation of the levator ani with optimal scan planning and statistical shape modeling.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Lee SL,Horkaew P,Caspersz W,Darzi A,Yang GZ

    更新日期:2005-03-01 00:00:00

  • Collagen vascular disease-related lung disease: high-resolution computed tomography findings based on the pathologic classification.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Tanaka N,Newell JD,Brown KK,Cool CD,Lynch DA

    更新日期:2004-05-01 00:00:00

  • Normalized accurate measurement of longitudinal brain change.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Smith SM,De Stefano N,Jenkinson M,Matthews PM

    更新日期:2001-05-01 00:00:00

  • Computed tomography of palatine tonsillar carcinoma.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Byrd SE,Schoen PJ,Gill G,Richardson M

    更新日期:1983-12-01 00:00:00

  • Baseline Cartilage Thickness and Meniscus Extrusion Predict Longitudinal Cartilage Loss by Quantitative Magnetic Resonance Imaging: Data From the Osteoarthritis Initiative.

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章,多中心研究


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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章,多中心研究


    authors: Chang KJ,Rekhi SS Jr,Anderson SW,Soto JA

    更新日期:2011-01-01 00:00:00

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Senda M,Tamaki N,Yonekura Y,Tanada S,Murata K,Hayashi N,Fujita T,Saji H,Konishi J,Torizuka K

    更新日期:1985-09-01 00:00:00

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


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    更新日期:1991-05-01 00:00:00

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章,评审


    authors: Venkatesh SK,Yin M,Ehman RL

    更新日期:2013-11-01 00:00:00

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    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章


    authors: Yu L,Shiung M,Jondal D,McCollough CH

    更新日期:2012-07-01 00:00:00