Nodular hepatocellular carcinoma: variation of tumor conspicuity on single-level dynamic scan and optimization of fixed delay times for two-phase helical CT.

Abstract:

PURPOSE:The purpose of this work was to determine the optimal delay times in two-phase helical CT for nodular hepatocellular carcinoma (HCC). METHOD:Twenty-four patients with nodular HCC (size 2.1-6.7 cm, mean 4.2 cm) were divided into three groups to undergo single-level dynamic CT with 150 ml of contrast material (iodine load of 45 g) at a rate of 3 ml/s. CT acquisition started 10, 30, or 60 s after the injection for each group, respectively, and lasted for 110 or 120 s. The optimal 20 s windows that allowed a tumor-to-liver contrast of >10 HU were determined in the pooled tumor-to-liver contrast curve. RESULTS:The determined temporal windows were 36-56 and 130-150 s, respectively. However, each window was not appropriate in seven (33%) and five (36%) patients because of the individual variations of the contrast curve. CONCLUSION:There is no optimal fixed delay time that is appropriate in all individual patients. The best delay times are 36 and at least 130 s with our injection protocol.

journal_name

J Comput Assist Tomogr

authors

Lee KH,Choi BI,Han JK,Jang HJ,Kim TK,Han MC

doi

10.1097/00004728-200003000-00005

keywords:

subject

Has Abstract

pub_date

2000-03-01 00:00:00

pages

212-8

issue

2

eissn

0363-8715

issn

1532-3145

pii

00004728-200003000-00005

journal_volume

24

pub_type

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