Hypoglossal nerve palsy missed and misinterpreted: the hidden skull base.

Abstract:

OBJECTIVE:Dysarthria and tongue swelling may be seen with hypoglossal nerve palsy, and on cross-sectional imaging studies, tongue denervation can be misinterpreted as a primary base-of-tongue mass. Understanding radiological patterns of tongue denervation is important to prevent misinterpretation. Close evaluation of the skull base is critical as hypoglossal palsies resulting from pathology here are often overlooked. METHODS:Neck and brain magnetic resonance imaging studies obtained in 7 adult patients referred to our institution with clinically and/or radiologically suspected tongue base masses were retrospectively reviewed. Outside imaging evaluations were misinterpreted as base-of-tongue tumors in 3 patients, incorrectly read as normal in 2, and skull base pathologies were missed in 5. RESULTS:All 7 patients showed magnetic resonance imaging findings typical of tongue denervation: T2-weighted hyperintensity of involved hemitongue, protrusion of the tongue into oropharynx, variable fatty infiltration. All 5 skull base masses involved hypoglossal canal (4 metastases, 1 multiple myeloma; 4 newly diagnosed cancers). Two patients had internal carotid artery dissections at the skull base. CONCLUSIONS:To avoid misinterpretation of tongue denervation for tongue base mass, understanding of tongue innervations and classic imaging findings of hypoglossal denervation are essential. Careful inspection of skull base is paramount to avoid overlooking these hidden pathologies.

journal_name

J Comput Assist Tomogr

authors

Learned KO,Thaler ER,O'Malley BW Jr,Grady MS,Loevner LA

doi

10.1097/RCT.0b013e318268ec18

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

718-24

issue

6

eissn

0363-8715

issn

1532-3145

pii

00004728-201211000-00014

journal_volume

36

pub_type

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