Abstract:
:This investigation is devoted to the study of the time-course of a cytokines panel (IL-4, IL-6, IFN-gamma, GM-CSF) in plasma samples from migraine patients. The data obtained during challenged migraine crises was compared to the baseline values. Time-data series analysis showed a fall after a challenge test for IL-4 and IL-6 plasma levels and an opposite trend for gamma-IFN and GM-CSF levels. The implication of this phenomenon in dietary migraine is not readily evident. There may possibly be an activation of this cytokine network together with the well-known impairment in the neuropeptidergic system, considering the close links between interleukins and other cytokines and the neuro-mediators of pain, such as histamine and 5-HT.
journal_name
Headachejournal_title
Headacheauthors
Martelletti P,Stirparo G,Rinaldi C,Frati L,Giacovazzo Mdoi
10.1111/j.1526-4610.1993.hed3310524.xsubject
Has Abstractpub_date
1993-11-01 00:00:00pages
524-7issue
10eissn
0017-8748issn
1526-4610journal_volume
33pub_type
杂志文章相关文献
HEADACHE文献大全abstract::The aim of the study was to compare adult migraine discordant full siblings in terms of personality and psychosocial environment during childhood. The study, involving 30 sibling pairs and use of various personality instruments (Eysenck Personality Inventory [EPI], Color Word Test [CWT], Visual Aftereffects [VAE], Met...
journal_title:Headache
pub_type: 杂志文章
doi:10.1046/j.1526-4610.1997.3703159.x
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:In previous studies, pregnancy has been associated with less headache, but the influence of parity on this association is largely unknown. OBJECTIVES:To examine the prevalence of headache and migraine among pregnant women, and explore the relation of headache to parity in a large, population-based study. M...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2009.01438.x
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Though symptomatic medication overuse is believed to play a major role in progression from episodic to chronic or transformed migraine (TM), population-based longitudinal data on these agents are limited. OBJECTIVES:To assess the role of specific classes of acute medications in the development of TM in epis...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2008.01217.x
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the prevalence of migraine/severe headaches in those with and without general obesity and abdominal obesity (Abd-O) and the effect of gender and age on this relationship. BACKGROUND:General, or total body obesity (TBO), as estimated by body mass index, is a risk factor for migraine chronification...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2009.01459.x
更新日期:2010-01-01 00:00:00
abstract::A 25-year-old man, subject to bouts of left supraorbital cluster headache on an annual basis over the previous 8 years, volunteered for MRI angiography during an active period. Studies were conducted before and during a typical cluster headache attack induced by alcohol. MRI angiography failed to show dilatation of th...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.1994.hed3408463.x
更新日期:1994-09-01 00:00:00
abstract::We present a patient with treatment refractory short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) who was found to have low levels of serum testosterone supporting the hypothalamic connection to this trigeminal autonomic cephalalgia. Clomiphene citrate therapy induce...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2005.05143_2.x
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Variables that are thought to precipitate migraine or tension-type headache episodes in children hitherto have only been studied using retrospective reports. As such, there is little empirical evidence to support the actual predictive association between presumed headache triggers and actual headache occurre...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2009.01586.x
更新日期:2010-05-01 00:00:00
abstract::Following tooth pulp extirpation, some subjects suffer from persistent pain which affects edentate sites in absence of any local pathology. As regards this peculiar pain, called phantom tooth pain (PTP), what is puzzling is the fact there is a low prevalence of PTP in a very large population showing identical conditio...
journal_title:Headache
pub_type: 临床试验,杂志文章
doi:10.1111/j.1526-4610.1991.hed3109577.x
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND:The buildup time of migraine headaches has not been well delineated in publications to date and we are aware of patients whose migraines last well over 72 hours. More concentration on these factors in the assessment of patients might lead to more appropriate therapeutic choices. METHOD:Prospective ascertain...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2006.00608.x
更新日期:2006-11-01 00:00:00
abstract::Patients with cluster headaches have been reported to have low serum ionized magnesium levels. We examined the possibility that patients with cluster headaches and low ionized magnesium levels may respond to an intravenous infusion of magnesium sulfate. Thirty-eight infusions of magnesium sulfate were given to 22 pati...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.1995.hed3510597.x
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVES:This study evaluated the long-term safety of oral almotriptan 12.5 mg for the treatment of multiple migraine episodes in adolescents over a 12-month period. Efficacy outcomes were assessed as a secondary objective. METHODS:Adolescent migraineurs aged 12-17 years were enrolled in this 12-month, open-label st...
journal_title:Headache
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/j.1526-4610.2010.01655.x
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy and tolerability of sumatriptan nasal spray (NS) (5, 20 mg) versus placebo in the acute treatment of migraine in adolescent subjects. BACKGROUND:Currently, no triptan is approved in the United States for the treatment of migraine in adolescent subjects (12 to 17 years). In a previous ...
journal_title:Headache
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1526-4610.2006.00339.x
更新日期:2006-02-01 00:00:00
abstract::Flunarizine plasma concentrations and side effects were evaluated in migraine patients during a 3 month course of prophylactic treatment. Plasma concentrations did not correlate with daily dose (in mg/kg). Mean flunarizine levels were higher in patients showing sleepiness or sedation. Weight gain was independent of pl...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.1990.hed3006369.x
更新日期:1990-05-01 00:00:00
abstract::The intimate relationship between sleep and headache has been recognized for centuries, yet the relationship remains clinically and nosologically complex. Headaches associated with nocturnal sleep have often been perceived as either the cause or result of disrupted sleep. An understanding of the anatomy and physiology...
journal_title:Headache
pub_type: 杂志文章
doi:10.1046/j.1526-4610.2003.03055.x
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of ubrogepant on patient-reported functional disability, satisfaction with study medication, and global impression of change. BACKGROUND:Ubrogepant is a small-molecule, oral calcitonin gene-related peptide receptor antagonist indicated for the acute treatment of migraine. In 2 phase ...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/head.13766
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVE:To describe acute headache diagnoses in women presenting emergently in the postpartum period and to determine which factors may be associated with secondary vs primary headache. BACKGROUND:Hormonal, vascular, and procedural factors elevate the risk for both secondary and primary headache disorders in the pos...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/head.13279
更新日期:2018-06-01 00:00:00
abstract::The ideal migraine medication would provide rapid “one and done” treatment of migraine for all sufferers. Unfortunately, no such intervention is available. While most people respond to triptans or DHE, some will need to combine these with an NSAID, or will choose to use an NSAID alone because of personal preference or...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/head.12474
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy of celecoxib for treatment of withdrawal headache vs prednisone in patients with medication overuse headache (MOH). METHODS:In this prospective, double-blind, parallel-group clinical trial, 97 consecutive subjects with MOH were randomized (simple randomization using computer-generated...
journal_title:Headache
pub_type: 杂志文章,随机对照试验
doi:10.1111/head.12487
更新日期:2015-01-01 00:00:00
abstract::Migraine shares a complex and poorly understood relationship with sleep. Patients consistently report poor sleep prior to migraine attacks and during them, identifying poor sleep as a migraine trigger. However, anecdotally, sleep is reported to serve a therapeutic role in terminating headache. Are the associations bet...
journal_title:Headache
pub_type: 杂志文章,评审
doi:10.1111/head.13358
更新日期:2018-07-01 00:00:00
abstract::This review aims to understand the prevalence of premonitory symptoms in migraine, postulate their mechanisms, and compare these with functional imaging studies. A thorough literature review was conducted using PubMed for prevalence studies of premonitory symptoms in migraine and functional imaging studies in the prem...
journal_title:Headache
pub_type: 杂志文章,评审
doi:10.1111/head.12572
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Headache is commonly reported in patients presenting with orofacial pain. It has only recently been demonstrated that headache-related disability is high in orofacial pain patients. Traumatic life events (TLEs) such as sexual abuse, physical abuse, and post-traumatic stress disorder (PTSD) are also common in...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2008.01182.x
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:To determine whether headache disorders are a risk factor for the development of new onset hypothyroidism. BACKGROUND:Past studies have reported associations between headache disorders and hypothyroidism, but the directionality of the association is unknown. METHODS:This was a longitudinal retrospective coh...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/head.12943
更新日期:2017-01-01 00:00:00
abstract::The presence of postural, myofascial, and mechanical abnormalities in patients with migraine, tension-type headache, or both headache diagnoses was compared to a headache-free control sample. Twenty-four control subjects were obtained from a convenience sampling and each was matched by age and sex to three patients wi...
journal_title:Headache
pub_type: 杂志文章
doi:10.1046/j.1526-4610.1999.3901021.x
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To examine the likelihood of response with continued galcanezumab treatment in patients with episodic or chronic migraine without initial clinical improvement. BACKGROUND:A percentage of patients with migraine may require additional time on pharmacotherapy but discontinue treatment prematurely. Additionally,...
journal_title:Headache
pub_type: 杂志文章,随机对照试验
doi:10.1111/head.13443
更新日期:2019-02-01 00:00:00
abstract::Ischemic colitis has not been reported in association with naratriptan therapy. We describe the occurrence of ischemic colitis in a patient who was treated with abortive doses of naratriptan for migraine and was also taking long-term oral contraceptives. Concurrent use of naratriptan and oral contraceptives should pro...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2005.05077_4.x
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVES:To review conjectured modes of action of migraine triggers and to present a new hypothesis about them. BACKGROUND:Migraine attacks are initiated in many migraineurs by a variety of "triggers," although in some patients no external trigger can be identified. Many triggers provoke attacks with such a short la...
journal_title:Headache
pub_type: 杂志文章,评审
doi:10.1111/j.1526-4610.2008.01230.x
更新日期:2009-02-01 00:00:00
abstract::The reactivity of posterior cerebral artery (PCA) to light stimulation was studied with transcranial Doppler in 9 migraine patients (5 with aura, 4 without aura) within six hours of the onset of headache (mean 115 +/- 78 minutes). The PCA mean flow velocity was recorded while the patient was in the dark and with the e...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.1993.hed3308417.x
更新日期:1993-09-01 00:00:00
abstract::The case of a 53-year-old woman is described, who since the age of 38 years had been suffering from a unilateral headache that was at first remitting, but then evolved into an unremitting course. The headache was burning in quality, located in the left forehead and face, and was accompanied by mild ipsilateral autonom...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.1992.hed3201039.x
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:In this study, we attempted to evaluate the response to lithium treatment and its tolerability in the prevention of episodic cluster headache (CH) and to identify clinical predictors of response. BACKGROUND:Verapamil and lithium are the most widely used drugs in the prevention of CH attacks. Lithium is consi...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2012.02183.x
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To describe the statuslike pattern of SUNCT (short-lasting unilateral neuralgiform pain with conjunctival injection and tearing) in two young women. BACKGROUND:SUNCT syndrome is a rare condition characterized by a short-lasting periocular pain associated with marked autonomic symptoms. Twenty-five cases have...
journal_title:Headache
pub_type: 杂志文章
doi:10.1046/j.1526-4610.2001.01151.x
更新日期:2001-09-01 00:00:00