Abstract：
OBJECTIVE:To determine whether headache disorders are a risk factor for the development of new onset hypothyroidism. BACKGROUND:Past studies have reported associations between headache disorders and hypothyroidism, but the directionality of the association is unknown. METHODS:This was a longitudinal retrospective cohort study using data from the Fernald Medical Monitoring Program (FMMP). Residents received physical examinations and thyroid function testing every 3 years during the 20 year program. Residents were excluded from the cohort if there was evidence of past thyroid disease or abnormal thyroid function tests at the first office visit. A diagnosis of a headache disorder was established by self-report of "frequent headaches," use of any headache-specific medication, or a physician diagnosis of a headache disorder. The primary outcome measure was new onset hypothyroidism defined as the initiation of thyroid replacement therapy or TSH ≥ 10 without thyroid medication. A Cox survival analysis with time dependent variables were used for the model. Headache disorders, age, sex, body mass index, income, smoking, narcotic use, and hypothyroidism-producing medications were independent variables in the model. RESULTS:Data from 8412 residents enrolled in the FMMP were used in the current study. Headache disorders were present in about 26% of the residents and new onset hypothyroidism developed in ∼7%. The hazard ratio for the development of new onset hypothyroidism was 1.21 (95% CI = 1.001, 1.462) for those with headache disorders. CONCLUSIONS:Headache disorders may be associated with an increased risk for the development of new onset hypothyroidism.
journal_name
Headachejournal_title
Headacheauthors
Martin AT,Pinney SM,Xie C,Herrick RL,Bai Y,Buckholz J,Martin VTdoi
10.1111/head.12943subject
Has Abstractpub_date
2017-01-01 00:00:00pages
21-30issue
1eissn
0017-8748issn
1526-4610journal_volume
57pub_type
杂志文章相关文献
HEADACHE文献大全abstract：:Central excitatory circuits could be involved in the pathophysiology of pain; particularly, the genesis of chronic pain. The "second pain" is the sensation that follows the initial pain after an appropriate nociceptive stimulus. The second pain is amplified by repeating the stimulus after brief intervals (temporal sum...
journal_title：Headache
pub_type： 杂志文章
doi：10.1046/j.1526-4610.1997.3708486.x
更新日期：1997-09-01 00:00:00
abstract：OBJECTIVE:A hallmark of migraine is photophobia. In mice, photophobia-like behavior is induced by calcitonin gene-related peptide (CGRP), a neuropeptide known to be a key player in migraine. In this study, we sought to identify sites within the brain from which CGRP could induce photophobia. DESIGN:We focused on the p...
journal_title：Headache
pub_type： 杂志文章
doi：10.1111/head.13917
更新日期：2020-10-01 00:00:00
abstract：:The history of post-traumatic headache begins in the middle of the 19th century, and its latest iteration has been defined in the International Headache Classification of 2004. Contrary to the latter, there are instances when mild head injury without symptoms or signs of concussion may evoke the pathophysiological cha...
journal_title：Headache
pub_type： 历史文章,杂志文章
doi：10.1111/j.1526-4610.2009.01462.x
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVE:To test whether chronic headache (>3 days/week) is more prevalent than episodic headache (<3 days/week) in patients with a previous history of significant head trauma. METHOD:We included 903 consecutive patients referred to a specialist center for headache during a period of 2 years. As the main parameter, w...
journal_title：Headache
pub_type： 杂志文章
doi：10.1046/j.1526-4610.2003.03010.x
更新日期：2003-01-01 00:00:00
abstract：:Migraine is a common disorder that starts at an early age and takes a variable pattern from intermittent to chronic headache with several exacerbations throughout a lifetime. Children and adolescents are significantly affected. If an acute headache is not aborted by outpatient migraine therapy, it often causes severe ...
journal_title：Headache
pub_type： 杂志文章,评审
doi：10.1111/head.12694
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:We present a case report of 2 migraine patients engaged in shift work, followed by a narrative review, to assess whether shift work influences headache-related disability and chronification of migraine. BACKGROUND:Numerous modifiable factors can lead to chronification of migraine and to higher headache-relat...
journal_title：Headache
pub_type： 杂志文章,评审
doi：10.1111/head.13622
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVE:To determine the pharmacological profile of frovatriptan. BACKGROUND:Frovatriptan is a new 5-HT(1B/1D) agonist developed for the treatment of migraine. METHODS:Pharmacological studies were performed using in vitro and in vivo techniques. RESULTS:Radioligand-binding studies showed that frovatriptan has a hi...
journal_title：Headache
pub_type： 杂志文章
doi：10.1046/j.1526-4610.42.s2.2.x
更新日期：2002-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the geographic location of the United Council for Neurologic Subspecialties (UCNS)-certified headache subspecialists as compared with ratios of expected migraine and chronic migraine populations in the United States. BACKGROUND:The UCNS is a professional medical organization that accredits fellow...
journal_title：Headache
pub_type： 杂志文章
doi：10.1111/head.12406
更新日期：2014-09-01 00:00:00
abstract：:If you vomit with migraines, get full-blown migraines upon awakening, or want rapid relief without injections, consider a nasal spray. Options include triptans (zolmitriptan [Zomig] or sumatriptan [Imitrex]), DHE (Migranal), or an NSAID (Sprix). ...
journal_title：Headache
pub_type： 杂志文章
doi：10.1111/head.12045
更新日期：2013-03-01 00:00:00
abstract：:The case of a 53-year-old woman is described, who since the age of 38 years had been suffering from a unilateral headache that was at first remitting, but then evolved into an unremitting course. The headache was burning in quality, located in the left forehead and face, and was accompanied by mild ipsilateral autonom...
journal_title：Headache
pub_type： 杂志文章
doi：10.1111/j.1526-4610.1992.hed3201039.x
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVES:The aim of our study is to determine the prevalence of migraine in Provincial Center of Edirne. METHODS:A systematic random sample of 386 inhabitants over 14 years old were interviewed face to face. Diagnosis of migraine was based on the International Headache Society (IHS) classification. RESULTS:Migraine...
journal_title：Headache
pub_type： 杂志文章
doi：10.1111/j.1526-4610.2005.05007.x
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to investigate the role of the chemokine receptor CX3CR1 in headaches and migraine. METHODS:Distribution of 2 polymorphisms of the chemokine receptor CX3CR1 (V249I and T280M) was determined in a population-based sample of 1179 elderly individuals. RESULTS:Heterozygotes for both CX...
journal_title：Headache
pub_type： 杂志文章
doi：10.1111/j.1526-4610.2007.01011.x
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVE:To describe a case series of 7 patients presenting cluster headache (CH) criteria and a substance use disorder, reported to a French Addictovigilance center. Then, to assess clinical, pharmacological, and neurobiological linkages between substance use and CH onset. BACKGROUND:CH patients are presenting a hig...
journal_title：Headache
pub_type： 杂志文章,评审
doi：10.1111/head.13516
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Primary headaches (migraine, tension headache, cluster headache, and other trigeminal autonomic cephalgias) are common in pregnancy and postpartum. It is unclear how to best and most safely manage them. OBJECTIVE:We conducted a systematic review (SR) of interventions to prevent or treat primary headaches in...
journal_title：Headache
pub_type： 杂志文章,评审
doi：10.1111/head.14041
更新日期：2021-01-12 00:00:00
abstract：OBJECTIVE:To examine circadian and menstrual patterns of migraine frequency in order to identify properties of the putative migraine generator. METHODS:Analysis of circadian and menstrual migraine attack frequency distributions, using between-interval differences as estimates, at each time point, of the derivative of ...
journal_title：Headache
pub_type： 杂志文章
doi：10.1111/j.1526-4610.2005.05134.x
更新日期：2005-07-01 00:00:00
abstract：:Traditionally, episodic primary headache disorders are characterized by a return of preheadache (normal) neurologic function between episodes of headache. In contrast, patients with chronic headache often do not return to normal neurologic function between headache attacks. This article proposes that the evolution fro...
journal_title：Headache
pub_type： 杂志文章
doi：10.1111/j.1526-4610.2004.04094.x
更新日期：2004-05-01 00:00:00
abstract：BACKGROUND:Migraine is a common cause of headache in adolescents. Assuming that the cerebral vasculature is involved in the pathophysiology of migraine, we compared cerebral vasoreactivity in adolescents both during a migraine attack and a headache-free interval. METHODS:A functional transcranial Doppler test utilizin...
journal_title：Headache
pub_type： 杂志文章
doi：10.1046/j.1526-4610.2003.03090.x
更新日期：2003-05-01 00:00:00
abstract：OBJECTIVE:To evaluate in a headache clinic population the relationship of childhood maltreatment on the prevalence of pain conditions comorbid with migraine. BACKGROUND:Childhood maltreatment is highly prevalent and has been frequently associated with recurrent headache. The relationship of maltreatment and pain has, ...
journal_title：Headache
pub_type： 杂志文章
doi：10.1111/j.1526-4610.2009.01558.x
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVE:To investigate the relationship between hyposerotonin and cranial microvascular responses to nitric oxide (NO). BACKGROUND:Although the mechanism underlying NO supersensitivity in migraine is still unclear, an alteration of the serotonin system is a possible explanation. METHODS:Wistar rats were divided int...
journal_title：Headache
pub_type： 杂志文章
doi：10.1046/j.1526-4610.2000.00040.x
更新日期：2000-04-01 00:00:00
abstract：:We present a novel case of a focal stabbing headache sharing features of primary stabbing headache that started and resolved with the onset and resolution of a course of self-limiting peripheral vertigo. The association of onset and improvement of the stabbing headaches support the trigeminal and vestibular reciprocal...
journal_title：Headache
pub_type： 信件
doi：10.1111/head.13208
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVES:The aim of our study was to investigate the prevalence of sleep disorders in chronic headache patients and to evaluate the role of psychiatric comorbidity in the association between chronic headache and sleep complaints. BACKGROUND:The prevalence of sleep disorders in chronic headache has been seldom invest...
journal_title：Headache
pub_type： 杂志文章,评审
doi：10.1111/j.1526-4610.2010.01711.x
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVE:To describe a standardized methodology for the performance of peripheral nerve blocks (PNBs) in the treatment of headache disorders. BACKGROUND:PNBs have long been employed in the management of headache disorders, but a wide variety of techniques are utilized in literature reports and clinical practice. MET...
journal_title：Headache
pub_type： 杂志文章,评审
doi：10.1111/head.12053
更新日期：2013-03-01 00:00:00
abstract：PREMISE:Headache is a common problem in medical practice. The International Classification of Headache Disorders (ICHD-3 beta)1 divides all headaches into two broad categories. Most headaches seen in practice belong to the category of primary headaches, where there is no underlying structural cause identifiable. Less t...
journal_title：Headache
pub_type： 杂志文章
doi：10.1111/head.12998
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVES:To describe patterns of perceived stress across stages of the migraine cycle, within and between individuals and migraine episodes as defined for this study. METHODS:Individuals with migraine aged ≥18 years, who were registered to use the digital health platform N1-HeadacheTM , and completed 90 days of dail...
journal_title：Headache
pub_type： 杂志文章
doi：10.1111/head.13943
更新日期：2020-09-12 00:00:00
abstract：BACKGROUND:Past studies have reported that connective tissue disorders (CTDs) are more common in patients with specific types of headache disorders. OBJECTIVES:The objectives of this study are (1) to review and critique the clinical studies reporting an association between joint hypermobility, CTDs and headache and (2...
journal_title：Headache
pub_type： 杂志文章,评审
doi：10.1111/head.12417
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:To investigate similarities and differences between patients with cluster headache and patients with migraine. BACKGROUND:Patients with migraine and patients with cluster headache are considered, by many clinical neurologists, to be different psychologically and socially. METHODS:Twenty-five age-matched pai...
journal_title：Headache
pub_type： 杂志文章
doi：10.1046/j.1526-4610.2002.02049.x
更新日期：2002-03-01 00:00:00
abstract：:Headache is a common disorder in the general population. It is often highly debilitating for the people affected and highly costly to society. Although we know much about primary headaches, little is known about secondary headaches which, however,are a frequent occurrence in the general population. A study conducted o...
journal_title：Headache
pub_type： 杂志文章,评审
doi：10.1111/j.1526-4610.2009.01390.x
更新日期：2009-05-01 00:00:00
abstract：:The aim of this study was to clarify a possible relationship between pollution and worsening of headache in the industrial city of Turin. From October 1992 to June 1993, we examined a group of 32 patients suffering from various headache types. During these months, they kept a daily record of their headaches and associ...
journal_title：Headache
pub_type： 杂志文章
doi：10.1046/j.1526-4610.1996.3604243.x
更新日期：1996-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the cross-sectional relationship between migraine and pregravid obesity; and to assess the risk of adult weight gain among women with history of a pediatric diagnosis of migraine. BACKGROUND:Obesity, comorbid with pain disorders including migraine, shares common pathophysiological characteristics...
journal_title：Headache
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1526-4610.2010.01833.x
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:The present study endeavored to identify predictors of headache during pregnancy, shortly after delivery, and at 8-week follow-up. BACKGROUND:Many women suffer from headaches during pregnancy and the post-partum period. However, little is known about factors that predict headache surrounding childbirth. MET...
journal_title：Headache
pub_type： 杂志文章
doi：10.1111/j.1526-4610.2011.02066.x
更新日期：2012-03-01 00:00:00
