Abstract:
:The cerebral response evoked by stimulation of the bulbar pyramidal tract in wood rats, like that of laboratory rats, consisted of a small alpha wave, almost obscured by a very large, superimposed r wave. The alpha wave behaved like a purely antidromic response, whereas the r wave behaved like a postsynaptic response, including a marked variability in amplitude on repeated trials. The contralateral forepaw and hindpaw motor sites mapped onto the somatic sensory foci for these two paws; further examination showed that the somatic sensory and motor representations were largely superimposed. An incipient sagittal fissure 1.5 mm lateral to the midline marked the boundary between limbic and neocortex. Because of their structural similarities and their differences in somatic sensory and motor organization, wood rats and laboratory rats are prime subjects for comparative study of the role of amalgamated and separate sensory and motor cortices in regulating movement and behavior.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Towe AL,Harrison TAdoi
10.1007/BF00228700subject
Has Abstractpub_date
1993-01-01 00:00:00pages
311-6issue
2eissn
0014-4819issn
1432-1106journal_volume
97pub_type
杂志文章abstract::It has long been assumed that the human central nervous system uses flexible combinations of several muscle synergies to effortlessly and efficiently control redundant movements. However, whether muscle synergies exist in the neural circuit remains controversial, and it is critical to examine the association between t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4253-5
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:Restoration of somatosensory deficits in humans requires a clear understanding of the neural representations of percepts. To characterize the cortical response to naturalistic somatosensation, we examined field potentials in the primary somatosensory cortex of humans. METHODS:Four patients with intractable e...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-019-05495-1
更新日期:2019-05-01 00:00:00
abstract::Besides luminance change, the pupil responds to changes in spatial pattern, color content and target motion. Our experimental results show that transient pupillary constriction can also be elicited by dichoptically viewing a change in stereoscopic stimuli composed of dynamic random-dot stereograms from an initially fl...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2161-1
更新日期:2005-01-01 00:00:00
abstract::Little is known about mechanisms used by the nervous system to encode time. In light of recent evidence, cerebellar cortex involvement in the learned timing of conditioned eyelid responses shows promise as an area of investigation into neural timing mechanisms. Lesion studies indicate that the cerebellar cortex is nec...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s002210050443
更新日期:1998-07-01 00:00:00
abstract::This study documents a bilateral projection from nucleus reticularis tegmenti pontis (NRTP) to the rostral aspect of the medial vestibular nucleus (MVN) in rabbits. Horseradish peroxidase injections in rostral MVN produced retrogradely labeled neurons in the caudal half of NRTP; caudal MVN injections produced negative...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237207
更新日期:1983-01-01 00:00:00
abstract::A double-labelling anatomical strategy employing horseradish peroxidase and tritiated, enzymatically inactive horseradish peroxidase allowed simultaneous visualization of corticospinal neurones and cortical neurones projecting to the dorsal column nuclei in cats. By this approach it is shown that although most cortica...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238364
更新日期:1981-01-01 00:00:00
abstract::The synapsins are presynaptic membrane-associated proteins involved in neurotransmitter release. They are differentially expressed in tissues and cells of the central and peripheral nervous system. In vestibular end organs of mammals, synapsin I-like immunoreactivity has been reported in efferent and afferent terminal...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2194-5
更新日期:2005-04-01 00:00:00
abstract::We examine cross-modality commonalities in visual and auditory imageries during fMRI scanning in a sample of healthy young adults. In a visual task combining viewed and imagined stimuli, 28 participants were asked to imagine novel scenes related to the other images, and in a similar auditory task combining heard and i...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-019-05492-4
更新日期:2019-05-01 00:00:00
abstract::Volume conduction measurements were carried out the brachial biceps, tibialis anterior and deltoid, in normal human subjects. Attenuation constant K and time constant tau of the muscle tissue transfer function were measured, and the average electrode uptake area calculated for the three muscles. The average number of ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238380
更新日期:1981-01-01 00:00:00
abstract::In a previous study we have demonstrated the existence of pulvinar (puv) cells which were optimally activated when a monkey executed reaching movements with his limbs (Acuña et al 1983). We now describe further observations in four Macaca nemestrina monkeys trained to perform goal directed reaching movements aimed at ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00230847
更新日期:1990-01-01 00:00:00
abstract::The mechanisms by which the nervous system coordinates multiple muscles for the control of finger movements are not well understood. One possibility is that groups of muscles may be enlisted into synergies by last-order inputs that project across multiple motor nuclei. In this study we investigated the role that tacti...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0643-z
更新日期:2006-10-01 00:00:00
abstract::The cerebellar projection from the facial and motor trigeminal nuclei was studied in the cat by means of retrograde axonal transport of wheat germ agglutinin-horseradish peroxidase and fluorescent tracers. The feline facial nucleus was cytoarchitectonically subdivided into ventromedial, ventrolateral, lateral, dorsal,...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247935
更新日期:1989-01-01 00:00:00
abstract::In dystonia, both sensory malfunctioning and an abnormal intermuscular low-frequency drive of 3-7 Hz have been found, although cause and effect are unknown. It is hypothesized that sensory processing is primarily disturbed and induces this drive. Accordingly, experimenter-controlled sensory input should be able to inf...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2174-x
更新日期:2010-05-01 00:00:00
abstract::Scientific interest has increased the influence of temperature in neurodegenerative and psychiatric disorders, and according to the monoamine hypothesis, depression is a neurochemical disorder arising from hypofunctioning of brain monoamine systems. Here, in vivo flow-oxymetry is applied to verify relationships betwee...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3443-2
更新日期:2013-10-01 00:00:00
abstract::This investigation was designed to study the effects of post-activation depression in different spinal pathways fed by group I afferents available to investigation in human subjects. It was precipitated by a recent investigation in the cat showing that-contrary to the general assumption-post-activation depression is n...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-2360-4
更新日期:2005-10-01 00:00:00
abstract::Sinusoidal translation while rotating at constant angular velocity about a vertical axis (translation while rotating, TWR) produces centripetal and translational accelerations along the direction of translation and an orthogonal Coriolis acceleration due to the translation in the rotating frame. Thus, a Coriolis accel...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2178-5
更新日期:2005-06-01 00:00:00
abstract::Peripheral sensory-motor neuropathy is one of the most frequent side effects of vincristine (VCR) administration, which often limits its usefulness in the treatment of a wide range of neoplastic diseases. The purpose of this work is to study VCR neurotoxicity in experimental animals from clinical, electrophysiological...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0499-2
更新日期:2006-08-01 00:00:00
abstract::The aim of this study was to examine the post-exercise effects of fatiguing the wrist extensor muscles of a single arm on postural tremor and muscle activity in both arms. Previous research has shown that, for neurologically normal subjects, the tremor seen within a single limb segment is uncorrelated to that seen con...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s00221-005-0050-x
更新日期:2005-12-01 00:00:00
abstract::Electrical stimulation over the cerebellum is known to transiently suppress the contralateral motor cortex in humans. However, projections from the cerebellar nuclei to the primary motor cortex are disynaptic excitatory pathways through the ventral thalamus. In the present investigation we studied facilitatory effects...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00221-004-1979-x
更新日期:2004-12-01 00:00:00
abstract::The distribution of S1 (first somatosensory area) and S2 (second somatosensory area) neurons projecting to the contralateral S2 was studied with horseradish peroxidase in normal adult cats and in cats aged between 129 and 248 days in which the injected S2 area had been deprived of some of its input by an earlier lesio...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235729
更新日期:1981-01-01 00:00:00
abstract::We investigated the accuracy with which, in the absence of vision, one can reach again a 2D target location that had been previously identified by a guided movement. A robotic arm guided the participant's hand to a target (locating motion) and away from it (homing motion). Then, the participant pointed freely toward t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-1833-1
更新日期:2004-07-01 00:00:00
abstract::Even the simplest volitional movements must be precisely coordinated with anticipatory postural adjustments. Little is currently known about the neural networks that coordinate these adjustments in healthy adults. We measured brain activity prior to movement during a bimanual load-lifting task, designed to elicit anti...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2470-5
更新日期:2011-01-01 00:00:00
abstract::Evidence is presented that simple cells in the cat striate cortex (area 17) fail to respond to two dimensional random patterns but respond vigorously to one dimensional patterns with identical power at the preferred orientation of the cell. Further observations suggest that complex cells inhibit simple cells so as to ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238391
更新日期:1981-01-01 00:00:00
abstract::A method is described for localized microapplication of drugs into nervous tissue of freely moving rats. Fairly constant release of material was observed over a period of more than three weeks. The amount of substance released was small because the rate of release was determined largely by diffusion rather than by mas...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238909
更新日期:1979-07-02 00:00:00
abstract::We investigated the capacities of human subjects to intercept moving targets in a two-dimensional (2D) space. Subjects were instructed to intercept moving targets on a computer screen using a cursor controlled by an articulated 2D manipulandum. A target was presented in 1 of 18 combinations of three acceleration types...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/pl00005769
更新日期:1997-10-01 00:00:00
abstract::The axon initial segment of cortical principal neurones contains an organelle consisting of two to four stacks of flat, membrane-delineated cisternae alternating with electron-dense, fibrillar material. These cisternal organelles are situated predominantly close to the synaptic junctions of GABAergic axo-axonic cell t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228742
更新日期:1994-01-01 00:00:00
abstract::The objective of this study was to investigate interhemispheric transcallosal connections between primary motor cortices noninvasively in awake human subjects. For this purpose, focal transcranial magnetic stimulation was performed on eight healthy, right-handed subjects and one patient with congenital collosal agenes...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227944
更新日期:1996-12-01 00:00:00
abstract::Intracortical inhibition was investigated in normal human volunteers by paired-pulse transcranial magnetic stimulation, using a new, computer-assisted threshold-tracking method. Motor threshold was defined as the stimulus amplitude required to evoke a motor evoked potential of 0.2 mV (peak-to-peak) in abductor pollici...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-001-0988-2
更新日期:2002-03-01 00:00:00
abstract::Integration of tactile afferent signals with motor commands is crucial for the performance of purposeful movements such as during manipulation of an object in the hand. To study the somatotopic organization of sensorimotor integration we applied electrical peripheral conditioning stimuli to a digit located near (homot...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050005
更新日期:2000-01-01 00:00:00
abstract::The ability to control speed and accuracy of goal directed aiming tasks underpins many activities of daily living. Recent evidence has begun to suggest that obesity can affect the control of movement. This study evaluated perceptual motor control of 183 normal weight, overweight, and obese participants using a discret...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5330-3
更新日期:2018-10-01 00:00:00