Abstract：
:Translation of poliovirus RNA is initiated by entry of ribosomes into the nucleotide sequence (internal ribosomal entry site; IRES) within the 5'-untranslated region (5'-UTR). Efficiency of this translation initiation in rabbit reticulocyte lysates (RRL) was very low and was greatly enhanced by addition of the ribosomal salt-wash fraction (RSW) prepared from HeLa cells. This stimulating activity in the RSW was partially purified by gel-filtration column chromatography and its molecular weight was estimated to be higher than 240,000. Several proteins that bind specifically to the poliovirus IRES were detected in the active fraction. Among those, a 57 kDa protein, recognized by antibodies against polypyrimidide tract-binding protein (PTB), was found. In addition, La protein (52 kDa) which is a human antigen recognized by antibodies from patients with autoimmune disorders was also detected. Further purification on a hydroxylapatite column resulted in considerable loss of the stimulatory activity, accompanied by a reduction of the apparent molecular weight of active component(s). These results suggest that fully active HeLa cell stimulatory factors for the translation initiation on poliovirus RNA function in RRL as a large complex consisted of several components including PTB and La protein.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Toyoda H,Koide N,Kamiyama M,Tobita K,Mizumoto K,Imura Ndoi
10.1007/BF01310034subject
Has Abstractpub_date
1994-01-01 00:00:00pages
1-15issue
1-2eissn
0304-8608issn
1432-8798journal_volume
138pub_type
杂志文章abstract：:Six isolates of Cassava brown streak virus (CBSV, genus Ipomovirus; Potyviridae) from the Lake Victoria basin in Uganda and Tanzania were characterized. Virus particles were 650 nm long. The complete coat protein (CP)-encoding sequences (1,101 nucleotides, nt) were 90.7-99.5 and 93.7-99.5% identical at the nt and amin...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0301-9
更新日期：2009-01-01 00:00:00
abstract：:The competition between different types of aphthoviruses (foot-and-mouth disease virus [FMDV]) for receptor site utilization was determined. The Southern African Territories (SAT) types of FMDV absorbed poorly to BHK-21 cells as measured by a radioactivity binding assay but grew to relatively high titers on these cell...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320782
更新日期：1982-01-01 00:00:00
abstract：:Hepatitis B virus (HBV) circulates as a collection of genetically related variants that evolve throughout the chronic infection. Those viral variants that have the greatest fitness are fixed. We recently showed different fitness for HBV variants involved in two epidemiological situations. To understand these fitness d...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-4090-5
更新日期：2019-02-01 00:00:00
abstract：:TT virus (TTV), the first human circovirus to be discovered, appears to be present in most people; less is known about the prevalence of the related TTV-like mini virus (TLMV). A sensitive nested PCR, specific for TLMV, detected the virus in 48% of 201 sera (Norwegian blood donors) previously found to have a 90% preva...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s705-002-8310-6
更新日期：2002-01-01 00:00:00
abstract：:Twenty TGEV isolates were compared by sequencing a 393-414 nucleotide stretch near the 5' end of the S gene, after amplification by RT-PCR. This part of the S gene is known to show considerable variation between porcine, canine and feline coronaviruses and is completely deleted from porcine respiratory coronaviruses. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050191
更新日期：1997-01-01 00:00:00
abstract：:The association of Merkel cell polyomavirus (MCPyV) with Merkel cell carcinoma (MCC) in immunocompromised individuals has been revealed in a number of surveys. The study of MCPyV specific antibody titers and viral loads in such patients has a great attraction for research groups interested in viral reactivation. In th...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3186-z
更新日期：2017-04-01 00:00:00
abstract：:This study examines viral protein and DNA synthesis in Spodoptera frugiperda multicapsid nuclear polyhedrosis virus (SfMNPV) infections of S. frugiperda and Trichoplusia ni cells. A total of 28 infected cell specific polypeptides (ICSPs) were detected in the productive S. frugiperda cells. Of these, 14 were identified...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310626
更新日期：1990-01-01 00:00:00
abstract：:The family Astroviridae consists of two genera, Avastrovirus and Mamastrovirus, whose members are associated with gastroenteritis in avian and mammalian hosts, respectively. We serendipitously identified a novel porcine astrovirus in a fecal specimen from a domestic pig (Sus scrofa domestica) in Hungary. Sequencing of...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0827-5
更新日期：2011-01-01 00:00:00
abstract：:Torque teno sus virus 1 (TTSuV1) is a novel virus that has been found widely distributed in the swine population in recent years. Analysis of codon usage can reveal much about the molecular evolution of TTSuV1. In this study, synonymous codon usage patterns and the key determinants in the coding region of 29 available...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1480-y
更新日期：2013-01-01 00:00:00
abstract：:Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are selective for human immunodeficiency virus type 1 (HIV-1) and generally not effective on HIV-2 or simian immunodeficiency virus (SIV). Only SIVagm was found to be sensitive to NNRTIs. When the amino acid differences in RT between SIVmac and SIVagm were compa...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050170143
更新日期：2001-01-01 00:00:00
abstract：:The 3'-terminal nucleotides of the genome segments of influenza C/Taylor/47. C/Bavaria/79 and C/Johannesburg/1/66 were identified by two RNA sequencing techniques. These comprised 11 nucleotides (3' UCGUCUUCGUC) which were found to be conserved among the genome segments of each virus. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310664
更新日期：1984-01-01 00:00:00
abstract：:The base sequences of the coding region of the nucleoprotein (NP) genes of two H 10 influenza A viruses, one avian (virus N) and one mink virus, have been determined by primer extension. When the NP genes and the NP sequences derived from the only open reading frame of the two H 10 viruses were compared with those of ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01319816
更新日期：1988-01-01 00:00:00
abstract：:During infection with herpes simplex virus type 1 (HSV-1) the activity of tyrosine hydroxylase (TH) in PC12 pheochromocytoma cells was initially depressed reaching a nadir at 6 hours post-inoculation, but recovered rapidly with a return to baseline activity by 8 to 9 hours post-inoculation. Subsequently, TH activity a...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310965
更新日期：1985-01-01 00:00:00
abstract：:A reversed passive hemagglutination (RPHA) method was developed for the detection of bovine coronavirus in fecal specimens. Sheep erythrocytes fixed with glutaraldehyde, and then treated with tannic acid were coated with anti-bovine coronavirus rabbit antibodies purified by affinity chromatography using bovine coronav...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315291
更新日期：1984-01-01 00:00:00
abstract：:As a prerequisite for development of improved vaccines and diagnostic tools for control of the fish pathogen koi herpesvirus, or cyprinid herpesvirus 3 (CyHV-3), we have started to identify putative viral envelope and capsid proteins. The complete or partial CyHV-3 open reading frames ORF25, ORF65, ORF92, ORF99, ORF13...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2190-4
更新日期：2014-12-01 00:00:00
abstract：:A distinct strain of hollyhock yellow vein mosaic virus (HoYVMV) and Ludwigia leaf distortion betasatellite (LuLDB) were associated with yellow vein mosaic of hollyhock. The viral DNA genome (JQ911766) and betasatellite (JQ408216) shared highest nucleotide sequence identity (89.2 %) with HoYVMV (the only available seq...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2108-1
更新日期：2014-10-01 00:00:00
abstract：:Hepatitis E virus (HEV) is an unclassified, plus-strand RNA virus whose genome contains three open reading frames (ORFs). ORF1, the 5' proximal ORF of HEV, encodes nonstructural proteins involved in RNA replication which share homology with the products of the corresponding ORF of members of the alphavirus-like superf...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050070093
更新日期：2000-01-01 00:00:00
abstract：:During infection host histo-blood group antigens (HBGAs) act as attachment factors that interact with rabbit hemorrhagic disease virus (RHDV) and participate in the infectious process. In the present study, baculovirus expressing recombinant RHDV capsid protein (VP60r) as a vaccine immunogen was used to test its antig...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3509-8
更新日期：2017-11-01 00:00:00
abstract：:A full length cDNA copy of the genomic RNA of lettuce mosaic virus (LMV) was constructed under the control of an enhanced CaMV 35S promoter and of the NOS terminator. This construct was found infectious when inoculated to lettuce plants. The intron II of the bean nitrite reductase gene was engineered into the LMV FL c...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050474
更新日期：1998-01-01 00:00:00
abstract：:Aphidicolin, a specific inhibitor of cellular DNA polymerase alpha and of viral DNA polymerase, inhibits production of infectious virus and cellular and viral DNA synthesis of human cytomegalovirus (HCMV)-infected cells. On the other hand, 2',3'-dideoxynucleosides, inhibitors of DNA polymerases beta and gamma, do not ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310559
更新日期：1985-01-01 00:00:00
abstract：:Between 2005 and 2011, 23 lineages of circulating vaccine-derived polioviruses (cVDPVs) were detected in Nigeria with nonstructural region (NSR) of non-polio enterovirus C (NPEV-C) origin. However, no information exists on NPEV-C strains recombining with oral poliovirus type 2 vaccine strains (OPV2) to make type 2 cVD...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2322-x
更新日期：2015-03-01 00:00:00
abstract：:The alkaloids contained in Colchicum autumnale seeds are used in numerous medicines. Good quality seeds are difficult to obtain from this undomesticated plant. Therefore, a research program was set up aiming to cultivate C. autumnale in order to improve alkaloid contents and seed yields. In this context, a collection ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-004-0307-x
更新日期：2004-07-01 00:00:00
abstract：:The biological function of entomopoxvirus (EPV) spindles (inclusion bodies that lack virions), has not been elucidated. We characterized the function of EPV spindles in the cupreous chafer, Anomala cuprea (Coleoptera: Scarabaeidae). Spheroids or spheroids mixed with spindles of Anomala cuprea EPV were administered per...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050070103
更新日期：2000-01-01 00:00:00
abstract：:A viroid was isolated from symptomless Coleus blumei cultivar (cv.) 'Rainbow Gold' plants using the bidirectional PAGE method for analysis of small circular RNA molecules. The viriod was transmitted to viroid-free plants of Coleus blumei cv. 'Scarlet Dragonfly' by mechanical inoculation. Cloning and sequencing reveale...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01718222
更新日期：1996-01-01 00:00:00
abstract：:The synthesis of M protein of HVJ (Sendai virus) in rat glioma (C6) cells, as has previously been reported, is selectively reduced at a nonpermissive temperature of 39 degrees C. In this phenomenon no difference was found in the viral RNA synthesis and the stability of the viral RNAs between the permissive and nonperm...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310830
更新日期：1988-01-01 00:00:00
abstract：:In the current study, the complete genome sequence of a member of the family Astroviridae isolated from pigeons was determined through genetic characterization and phylogeny analysis. The isolated genome sequence was proposed to be that of pigeon avian nephritis virus (ANV), whose genome structure and characteristics ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-011-1034-8
更新日期：2011-09-01 00:00:00
abstract：:Human enterovirus 71 (EV71) causes hand, foot and mouth disease in children under 6 years of age, and the neurological complications of this virus can lead to death. Until now, no vaccines or drugs have been available for the clinical control of this epidemic. Macrophages can engulf pathogens and mediate a series of h...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1495-4
更新日期：2013-02-01 00:00:00
abstract：:HSV-2 infections suppress the antibody response to HSV-1 but do not impair the mouse cytomegalo virus (MCMV) antibody generating system. In contrast, the sheep red blood cell (SRBC) IgM response is impaired by preinfections with HSV-2 but not with HSV-1. From the time kinetics of this suppression it can be concluded t...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310741
更新日期：1987-01-01 00:00:00
abstract：:Here, we present the complete genomic sequence of duck enteritis virus (DEV) strain SD, isolated in China in 2012. The virus was virulent in experimentally infected 2-month-old ducks. The DEV SD genome is 160,945 base pairs (bp) in length. The viral genome sequence, when compared to that of strain DEV CSC, which was i...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04594-7
更新日期：2020-07-01 00:00:00
abstract：:Rabbit convalescent and hyperimmune sera, human patient and blood donor sera, as well as cerebrospinal fluids of humans with herpes simplex virus encephalitis all recognize similar major antigenic components in herpes simplex virus infected rabbit or human cells as shown by electrophoretic analysis of immunoprecipitat...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314855
更新日期：1977-01-01 00:00:00
