Abstract:
:The gain (ratio of eye velocity to head velocity) of the initial horizontal vestibulo-ocular reflex (VOR) was calculated in 12 normal subjects over 350 ms during impulsive, unpredictable whole body rotation under three conditions: (1) darkness; (2) visual enhancement of the VOR, while the subjects fixated a stationary target; and (3) visual cancellation of the reflex, while subjects fixated a target that rotated with the head. The gain of the initial 80 ms of compensatory eye movement increased significantly during visual fixation in 5 subjects and decreased during attempted VOR cancellation in 3 subjects, when compared with VOR gain in darkness. Compensatory vestibular smooth eye movements were slowed, becoming curved at the onset of VOR cancellation, at mean latencies ranging from 78 to 149 ms in individual subjects (group mean 128 ms). At about 190 ms, quick phases moved the eyes in the same direction as head and target motion. The subsequent vestibular eye movements were about 50% slower than the initial smooth eye movements, indicating more effective cancellation. Visual enhancement of the VOR can occur prior to the onset of pursuit, providing evidence that fixation and smooth pursuit are distinct ocular motor systems. Visual cancellation of the VOR also begins prior to smooth pursuit initiation and becomes more effective after the latency of smooth pursuit.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Johnston JL,Sharpe JAdoi
10.1007/BF00239596subject
Has Abstractpub_date
1994-01-01 00:00:00pages
302-8issue
2eissn
0014-4819issn
1432-1106journal_volume
99pub_type
临床试验,杂志文章abstract::We investigated the association between the degree of lesion overlap with the corticospinal tract and walking performance before and after 4-weeks of partial body weight support (PBWS) treadmill training in 18 individuals (ten male, eight female) with a mean age 59 +/- 13 years (mean +/- SD), range 32-74 years, who we...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-007-1237-0
更新日期:2008-03-01 00:00:00
abstract::Lengthening and shortening contractions are the fundamental patterns of muscle activation underlying various movements. It is still unknown whether or not there is a muscle-specific difference in such a fundamental pattern of muscle activation. The purpose of this study was, therefore, to investigate whether or not th...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0743-9
更新日期:2007-04-01 00:00:00
abstract::Empathy, i.e., the ability to perceive and share another person's affective state, is associated with activity in a complex neural network, including the anterior insula, the anterior and mid-cingulate cortex, and the lateral prefrontal cortex. Here, we were interested in the question how facial emotions influence the...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4731-4
更新日期:2016-11-01 00:00:00
abstract::The flow of information in the sensorimotor cortex may determine how somatic information modulates motor cortex neuronal activity during voluntary movement. Electrophysiological recordings and neuroanatomical tracing techniques were used to study the connections between the primary somatosensory cortex (SI) and the vi...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229854
更新日期:1995-01-01 00:00:00
abstract::Previous studies have proposed that selecting which hand to use for a reaching task appears to be modulated by a factor described as "task difficulty," defined by either the requirement for spatial precision or movement sequences. However, we previously reported that analysis of the movement costs associated with even...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5423-z
更新日期:2019-02-01 00:00:00
abstract::Inhibitory control plays an important role in goal-directed behavior. Although substantial inter-individual variability exists in the behavioral performance of response inhibition, the corresponding modulating neurochemical and neurophysiological mechanisms remain unclear. Thus, the present study aimed to explore the ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-017-5101-6
更新日期:2017-12-01 00:00:00
abstract::Efferents originating from the rat medial prefrontal cortex and projecting to diencephalic and mesencephalic structures were analyzed electrophysiologically. The antidromic activation technique was used in order to identify cortical neurons which innervate the medio-dorsal nucleus of the thalamus (MD), lateral habenul...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239191
更新日期:1983-01-01 00:00:00
abstract::This review summarizes anatomical and electrophysiological observations related to corticovestibular interactions as a step toward understanding their possible functions. Vestibular information is represented in at least three distinct regions of the cerebral cortex in cats and monkeys: the parietal and somatosensory ...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/pl00005786
更新日期:1997-10-01 00:00:00
abstract::We have previously shown that sinusoidal galvanic vestibular stimulation (sGVS), delivered bilaterally at 0.2-2.0 Hz, evokes a potent entrainment of sympathetic outflow to muscle and skin. Most recently, we showed that stimulation at 0.08-0.18 Hz generates two bursts of modulation of muscle sympathetic nerve activity ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3090-z
更新日期:2012-06-01 00:00:00
abstract::We applied vibration at various rates to the biceps tendon of a passive, restrained arm in normal human subjects and measured its effect on the perception of forearm position and the perception of forearm velocity. The disturbances of limb position perception and limb velocity perception depended on the vibration rate...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00269450
更新日期:1987-01-01 00:00:00
abstract::We studied 12 patients with Parkinson's disease (PD): 6 with postural instability (Hoehn and Yahr Stage 3) and 6 without (Stage 2 or 2.5), using a quantitative test based on the clinical pull test. Their findings were compared with those for 12 healthy controls. The patients on their usual medications were pulled eith...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-019-05553-8
更新日期:2019-07-01 00:00:00
abstract::This investigation was designed to study the effects of post-activation depression in different spinal pathways fed by group I afferents available to investigation in human subjects. It was precipitated by a recent investigation in the cat showing that-contrary to the general assumption-post-activation depression is n...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-2360-4
更新日期:2005-10-01 00:00:00
abstract::Three patients with cerebellar limb ataxia and three age-matched controls performed arm-pointing movements towards a visual stimulus during an experimental procedure using a double-step paradigm in a three-dimensional space. Four types of trajectories were defined: P1, single-step pointing movement towards the visual ...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s002210050361
更新日期:1998-04-01 00:00:00
abstract::Early blindness in humans and experimental visual deprivation in animal models are known to induce compensatory somatosensory and/or auditory activation of the visual cortex. An abnormal hydrocephalic cat with extreme malformation of the visual system, born in our breeding colony, rendered a good model system for inve...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002219900295
更新日期:2000-03-01 00:00:00
abstract::Changing direction during walking is a common task humans encounter every day. This destabilizing event requires the central nervous system (CNS) to quickly produce an appropriate response, maintain stability, and propel the body in the intended direction. Previous research has demonstrated that 'individuals with mult...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-3873-5
更新日期:2014-06-01 00:00:00
abstract::The development of the electromyogram (EMG) of tibialis anterior (TA) and medial gastrocnemius (GM) during locomotion was studied in normal rats from the onset of quadruped walking (postnatal day 10, P10) until P42. The objectives were to relate signal properties of the EMG and coordination of muscle activity to funct...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229036
更新日期:1993-01-01 00:00:00
abstract::The praxis system comprises a network of brain regions dedicated to complex skilled movements. Following suggestions of a female advantage on learned movements (Chipman and Hampson in Neuropsychologia 44(12):2315-2329, 2006), we investigated how males and females acquire skilled movements. Subjects viewed and imitated...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2351-y
更新日期:2010-08-01 00:00:00
abstract::Several recent studies have provided support for the view that tactile stimuli/events are remapped into an abstract spatial frame of reference beyond the initial somatotopic representation present in the primary somatosensory cortex. Here, we demonstrate for the first time that the extent to which this remapping of ta...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1510-x
更新日期:2008-11-01 00:00:00
abstract::The importance of the caudal ventrolateral medulla (CVLM) in mediating vagal cardiopulmonary (Bezold-Jarisch reflex) reflex activity was studied in urethane-anaesthetized rats. Unilateral electrolytic lesion of the CVLM markedly attenuated Bezold-Jarisch reflex responses (hypotension and bradycardia) elicited by intra...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00230698
更新日期:1989-01-01 00:00:00
abstract::The luminance detectors in the olivary pretectal nucleus, which are likely candidates mediating the pupillary light reflex, responded to all frequencies of sinusoidally modulated light up to 12-25 Hz. At low frequencies (0.05-4.0 Hz) the luminance detectors responded with modulated firing to different stimulation rate...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237669
更新日期:1985-01-01 00:00:00
abstract::It has recently been suggested that time perception and motor timing are influenced by the presence of biological movements and animacy in the visual scene. Here, we investigated the interactions among timing, speed and animacy in two experiments. In Experiment 1, observers had to press a button in synchrony with the ...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00221-012-3338-7
更新日期:2013-02-01 00:00:00
abstract::Simultaneous recordings of action potentials (APs) of multiple single motor units (MUs) were obtained in brachialis and biceps (caput breve) muscles during sinusoidally modulated isometric contractions of elbow flexor muscles and during sinusoidal flexion/extension movements in the elbow against a preload in the exten...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s002210050205
更新日期:1997-10-01 00:00:00
abstract::Optokinetic circular vection (CV) was investigated in 12 subjects using an optokinetic pattern rotating at 15 degrees /s, 30 degrees /s, or 60 degrees /s, and four viewing conditions: FOL, subjects attentively followed details of pattern; STA, subjects stared at the pattern; SUP, subjects suppressed their optokinetic ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-002-1104-y
更新日期:2002-06-01 00:00:00
abstract::Slow eye movements were observed while the monkey fixated on a subject-stationary, small target light in front of a moving optokinetic drum in an attempt to suppress optokinetic nystagmus (OKN). These slow eye movements of low amplitude were directed opposite to the moving optokinetic stimulus and, hence, were not ide...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248564
更新日期:1987-01-01 00:00:00
abstract::The hypothesis that anticipatory postural adjustments (APAs) may concur in generating the directional preference experienced during limb coupled movements was tested by measuring the electromyographic and mechanic postural actions elicited when moving: (1) one single arm/hand and, (2) both limbs, iso- or antidirection...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1470-1
更新日期:2008-09-01 00:00:00
abstract::Transcranial direct current stimulation (TDCS) is a non-invasive form of brain stimulation applied via a weak electrical current passed between electrodes on the scalp. In recent studies, TDCS has been shown to improve learning when applied to the prefrontal cortex (e.g., Kincses et al. in Neuropsychologia 42:113-117,...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2764-2
更新日期:2011-08-01 00:00:00
abstract::Single cell activity was recorded in area 18 during optokinetic nystagmus (OKN) in awake cats. The search coil technique was used to record the horizontal and vertical eye movements. Cells showing direction specific responses to a moving large area random dot pattern (70%) were tested with different velocities in the ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231138
更新日期:1984-01-01 00:00:00
abstract::Studies of the effects of physical activity on cognition suggest that aerobic fitness can improve cognitive abilities. However, the physiological mechanisms for the cognitive benefit of aerobic fitness are less well understood. We examined the association between aerobic fitness and cerebrovascular function with neuro...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5230-6
更新日期:2018-05-01 00:00:00
abstract::During transient, high-acceleration rotation, performance of the normal vestibulo-ocular reflex (VOR) depends on viewing distance. With near targets, gain (eye velocity/head velocity) enhancement is manifest almost immediately after ocular rotation begins. Later in the response, VOR gain depends on both head rotation ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002219900266
更新日期:2000-02-01 00:00:00
abstract::This study examined the hypothesis that the mirror reflection of one hand's movement directly influences motor output of the other (hidden) hand, during performance of bimanual drawing. A mirror was placed between the two hands during bimanual circle drawing, with one hand and its reflection visible and the other hand...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-1831-3
更新日期:2004-07-01 00:00:00