Abstract：
:Angiotensin II is a prothrombotic vasoconstrictor. This study proves that many hypertensives are hypercoagulable and at risk for myocardial infarction. The modified recalcification time (MRT) test, used to assess hypercoagulability, incorporates the role of tissue factor in coagulation by activating the monocyte with endotoxin to release latent tissue factor. Aliquots of citrated blood obtained from hypertensives and normotensive controls were placed in two groups of vials, one with saline (group S) and one with endotoxin (group E). All vials were incubated at 37 degrees C for 2 hours, citrate neutralized with calcium chloride, and the MRT (in minutes) for group S (MRT S) and for group E (MRT E) was determined. Mean MRT S values +/- standard deviation (SD) for hypertensives (n = 25) and for controls (n = 27) were 6.4 +/- 1.2 and 6.8 +/- 1.2, respectively. The MRT E values were 4.3 +/- 1.2 and 5.7 +/- 0.9 for the hypertensives and controls, respectively. The MRT E, not the MRT S, was significant. Hypertensives had MRT E values < 4.5 minutes, and by our established criteria, were hypercoagulable. We conclude that because hypercoagulability is a risk factor for thrombosis, hypertensives with short MRT E values may be at increased risk for myocardial or other thrombotic events.
journal_name
J Natl Med Assocjournal_title
Journal of the National Medical Associationauthors
Miller MA,Spillert CR,Ponnudurai R,Bonthu S,Lazaro EJsubject
Has Abstractpub_date
1995-01-01 00:00:00pages
71-2issue
1eissn
0027-9684issn
1943-4693journal_volume
87pub_type
杂志文章abstract：:Attributes of age, tobacco use, and alcohol consumption were studied in order to elucidate their roles in the increased risks of blacks for selected neoplasms. Black cancer patients with and without liver cirrhosis were compared by cancer sites, age, tobacco usage, and alcohol consumption. Subsequently, non-cirrhotic ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1978-08-01 00:00:00
abstract：:This survey assessed the reported frequency of breast self-examination (BSE): the knowledge of the technique and attitudes regarding the self-exam of 180 black women. Most respondents indicated having practiced the exam during the previous year, and 50% reported practicing it monthly or more often. Less than half of t...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：BACKGROUND:Although several studies have outlined the need for and benefits of diversity in academia, the number of underrepresented minority (URM) faculty in academic health centers remains low, and minority faculty are primarily concentrated at the rank of assistant professor. In order to increase the diversity of th...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-09-01 00:00:00
abstract：:Posttraumatic stress disorder (PTSD) has previously been associated with increased risk for a variety of chronic medical conditions and it is often underdiagnosed in minority civilian populations. The current study examined the effects of resilience on the likelihood of having a diagnosis of PTSD in an inner-city samp...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)30381-3
更新日期：2011-07-01 00:00:00
abstract：INTRODUCTION:This book review analyzes the complex and profound impact active religious participation has on relationships and family outcomes among African Americans and Latinos. In Soul Mates, Wilcox and Wolfinger discuss the legacy of slavery and Jim Crow laws and the resulting devastating effects on African America...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：10.1016/j.jnma.2016.08.007
更新日期：2016-01-01 00:00:00
abstract：:The three leukotriene (LT) modifiers approved for use in the United States, zileuton, zafirlukast, and montelukast, are the first new class of therapeutic agents to be introduced in 20 years for the treatment of asthma. These agents are referred to as leukotriene modifiers and have clearly demonstrated the ability to ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章,评审
doi：
更新日期：1999-08-01 00:00:00
abstract：:The following is a review of the literature concerning hidradenitis suppurativa with emphasis on aspects of this disease which suggest that it may be a result of altered host-defense mechanisms.Deep fistula formation, anemia, and the development of carcinoma are complications seen only in disease affecting the periana...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1978-05-01 00:00:00
abstract：:Multiple Myeloma (MM) is a neoplastic disorder derived from the malignant proliferation of monoclonal plasma cells. It is characterized by the overproduction of immunoglobulins (Ig). We report a rare case in which bulbar palsy was the initial manifestation of IgG-MM. A 66-year-old woman initially presented with progre...
journal_title：Journal of the National Medical Association
pub_type：
doi：10.1016/j.jnma.2020.12.007
更新日期：2021-01-18 00:00:00
abstract：:Collagenous colitis has been associated with autoimmune diseases. Co-occurence of systemic sclerosis and collagenous colitis is particularly rare. Herein, we described a 65-year-old woman with systemic sclerosis whose diarrhea and abdominal cramping were due to collagenous colitis. We have reviewed the clinical and hi...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-06-01 00:00:00
abstract：INTRODUCTION:Black individuals continue to be underrepresented in clinical trials despite efforts by the National Institutes of Health and the Federal Drug Administration to increase their enrollment. Health care providers play a critical role in the recruitment of patients into clinical trials, as they have establishe...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2018.07.004
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:While African-American women tend to have greater bone mineral density (BMD) than caucasian women, they are still at risk of developing osteoporosis later in life. Clinical decision rules (i.e., algorithms) have been developed to assist clinicians identify women at greatest risk of low BMD. However, such tool...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：BACKGROUND:Diversity and inclusion are terms that have been used widely in a variety of contexts, but these concepts have only been intertwined into the discussion in healthcare in the recent past. It is important to have a healthcare workforce which represents the tapestry of our communities as it relates to race/ethn...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2020.03.014
更新日期：2020-06-01 00:00:00
abstract：:Stenosing tenosynovitis of the first dorsal compartment of the wrist (de Quervain's disease) is a common cause of radial wrist and hand pain and disability. Nonoperative management of the disease has been thought to provide only temporary relief of pain and swelling, while surgical intervention has been viewed as a mo...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1998-08-01 00:00:00
abstract：:Adynamic ileus due to invasion of the myenteric plexus of the small and large intestine was a significant symptom in a patient with a peritoneal mesothelioma. A record of this unusual complication was not found in the medical literature surveyed. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1987-07-01 00:00:00
abstract：:Ischemia and reperfusion in myocardial infarction and stroke are associated with upregulation of leukocyte adhesion molecules, which contributes to tissue injury by facilitating leukocyte adhesion and infiltration in the affected tissues. Surgical repair of the abdominal aortic aneurysm involves clamping and declampin...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2005-02-01 00:00:00
abstract：:Little is known about the adverse consequences of anemia during infancy or maternal anemia during pregnancy on the behavioral development of the infant. The present research investigates one aspect of these relationships. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1986-10-01 00:00:00
abstract：:Meager information exists regarding the morbidity of cancer surgery in obese patients, and it is generally assumed that surgery in the obese patient is attended with increased complications over those found in nonobese patients. A retrospective evaluation was undertaken at the Louisiana State University Medical Center...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1988-04-01 00:00:00
abstract：:Painful palmar and plantar erythema is an uncommon systemic complication of chemotherapy and has been reported in association with methotrexate, cystosine arabinoside, doxorubicin, and 5-fluorouracil. The authors report a case in which the syndrome was precipitated by hepatic artery infusion of 5-FUdR. The previous re...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1987-06-01 00:00:00
abstract：BACKGROUND:Hypertension is associated with left ventricular diastolic function abnormalities. There have been few studies evaluating left ventricular diastolic function in an African populace. MATERIALS AND METHODS:Ninety-eight hypertensives (52 females, 46 males) and 99 normal controls (49 females, 50 males) were rec...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:A Nigerian school boy with the syndrome of multiple jaw cysts, skeletal anomalies, and basal cell nevi is described and discussed. To the authors' knowledge, this is the first report of this syndrome in a black African. ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1980-03-01 00:00:00
abstract：PURPOSE:Older African Americans may be vulnerable to risks due to impaired healthcare access and understudied complementary and alternative medicine (CAM) use and other traditions. We describe CAM use among older African Americans in Baltimore, MD, examining associations among CAM and sociodemographic, health status, h...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)31475-9
更新日期：2008-10-01 00:00:00
abstract：:This article reports a rare case of primary signet-ring cell carcinoma of the bladder with transitional cell and adenocarcinoma variants and metachronous metastases to the penis and lungs. This combination of lesions has not previously been reported. Together, they portend widespread dissemination and an early demise ...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：:There are few reports in the medical literature of treatment of compression of the spinal cord by the use of radiation therapy alone. Laminectomy has been the standard procedure to relieve compression of the spinal cord and should be performed within 48 hours of initial symptoms. In this patient, radiation therapy was...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1979-03-01 00:00:00
abstract：:Racial disparities in quality of health are major issues affecting healthcare delivery. While substantial studies have been done in adults with end-stage renal disease (ESRD), similar studies are lacking in pediatric patients with ESRD. We retrospectively analyzed our transplant database from 1978-2002 to identify rac...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2006-02-01 00:00:00
abstract：OBJECTIVES:To examine the sexually transmitted infection (STI) and HIV testing practices of primary care providers (PCPs) practicing in predominantly Hispanic communities. METHODS:This is a cross-sectional study. PCPs were identified by matching ZIP codes of physician directories with ZIP codes of Los Angeles County a...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：:In a retrospective review of 100 consecutive cases of stab wounds to the chest, 44 patients were successfully treated with tube thoracostomy, 14 patients required thoracotomy, 17 patients with small pneumothoraces were observed, and 25 patients were asymptomatic. The overall mortality was 4%, operative mortality was 7...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1990-02-01 00:00:00
abstract：:Labetalol and hydrochlorothiazide (HCTZ) were compared for their efficacy in controlling hypertension of blacks in a prospective, double-blind study. Sixty-one adult patients with mild to moderate hypertension (standing diastolic blood pressure greater than or equal to 95 mm Hg and less than or equal to 114 mm Hg) wer...
journal_title：Journal of the National Medical Association
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1991-10-01 00:00:00
abstract：BACKGROUND:Black women in Minnesota and beyond have a greater burden of death due to some cancers than their White counterparts. Delayed screening and treatment may explain these disparate statistics. The purpose of this study was to work in collaboration with a local Black faith-based organization to gain an updated u...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/j.jnma.2019.02.006
更新日期：2020-10-01 00:00:00
abstract：:This study was undertaken to clarify the complex relationship between poverty and race with disease-specific mortality. Data from the 1987 National Health Interview Survey and the 1986 National Mortality Followback Survey were used to estimate standardized mortality ratios (SMRs) for various categories (all causes, al...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：BACKGROUND:Although studies have outlined the benefit of diversity in academic medicine, the number of underrepresented minority (URM) faculty remains low. In 1998, University of California, San Diego (UCSD) School of Medicine with the Hispanic Center of Excellence began a formalized proactive faculty development progr...
journal_title：Journal of the National Medical Association
pub_type： 杂志文章
doi：10.1016/s0027-9684(15)31449-8
更新日期：2008-09-01 00:00:00
