The effect of verapamil calcium antagonist on autonomic imbalance in migraine: evaluation by spectral analysis of beat-to-beat heart rate fluctuations.

Abstract:

:Abnormalities in autonomic control have been documented in migraine even during the headache-free interval. It has long been recognized that spectral analysis of heart rate (HR) fluctuations can reflect the autonomic function, especially the sympathetic to parasympathetic balance. This technique is the basis for a quantitative approach to the investigation of migraine applied in the present study. A 24-hour Holter ECG recording was performed for each subject in a group of five migraine patients during the interheadache period. In addition, shorter 5-minute-long recordings of blood flow (BF) and blood pressure (BP) were made in these patients in both supine and standing positions. Short, 256-second subtraces were taken every 30 minutes along the 24-hour ECG signal and were submitted, as well as the BF and BP traces, to A/D conversion and computation of the power spectrum of fluctuations in HR, BF, and BP. Spectral analysis of fluctuations in these hemodynamic parameters was performed in the migraine patients before and during the treatment with verapamil and compared to that of a healthy control group. This procedure enabled us to assess the autonomic function, the sympathetic vs parasympathetic balance, and their response to a change in position, before and during calcium blockade. A characteristic autonomic abnormality is revealed in the group of untreated migraine patients in supine position: enhanced low frequency (LF) fluctuations reflecting increased sympathetic sensitivity during the inter-headache phase. An exaggerated sympathetic response is measured in the migraine patients during the transition from supine to standing position with a concomitant nonsignificant decrease in parasympathetic response.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

Headache

journal_title

Headache

authors

Zigelman M,Appel S,Davidovitch S,Kuritzky A,Zahavi I,Akselrod S

doi

10.1111/j.1526-4610.1994.hed3410569.x

subject

Has Abstract

pub_date

1994-11-01 00:00:00

pages

569-77

issue

10

eissn

0017-8748

issn

1526-4610

journal_volume

34

pub_type

杂志文章

相关文献

HEADACHE文献大全
  • Reappraising the Tolosa-Hunt Syndrome Diagnostic Criteria: A Case Series.

    abstract:INTRODUCTION:Tolosa-Hunt syndrome (THS), a condition characterized by painful ophthalmoplegia and accompanied by cranial nerve palsies, remains as a diagnosis of exclusion. Nevertheless, the 3rd Edition of the International Classification of Headache Disorders (ICHD) has refined its diagnostic criteria to require the d...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13692

    authors: Mullen E,Rutland JW,Green MW,Bederson J,Shrivastava R

    更新日期:2020-01-01 00:00:00

  • Cluster headache with obstructive sleep apnea and periodic limb movements during sleep: a case report.

    abstract::We report the case of a man with episodic cluster headache who suffered from severe obstructive sleep apnea (OSA) as well as periodic limb movements during sleep (PLMS). His attacks of headache occurred primarily during sleep being timely to REM sleep as 90 to 120 minutes interval. OSAs were more frequent and prolonge...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2005.t01-3-05013.x

    authors: Pelin Z,Bozluolcay M

    更新日期:2005-01-01 00:00:00

  • The effect of pregnancy and parity on headache prevalence: the Head-HUNT study.

    abstract:BACKGROUND:In previous studies, pregnancy has been associated with less headache, but the influence of parity on this association is largely unknown. OBJECTIVES:To examine the prevalence of headache and migraine among pregnant women, and explore the relation of headache to parity in a large, population-based study. M...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2009.01438.x

    authors: Aegidius K,Zwart JA,Hagen K,Stovner L

    更新日期:2009-06-01 00:00:00

  • Morbidity and medication preferences of individuals with headache presenting to a community pharmacy.

    abstract:OBJECTIVE:To assess the degree of debilitation and the treatment views of individuals with headache presenting to a community pharmacy. BACKGROUND:Migraine and chronic daily headache are common poorly managed illnesses. Pharmacists recommend an over-the-counter "headache product" to customers more than 53 000 times da...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2004.04016.x

    authors: Wenzel RG,Schommer JC,Marks TG

    更新日期:2004-01-01 00:00:00

  • Migraine Progression: A Systematic Review.

    abstract:BACKGROUND:Migraine is a common and often debilitating neurological disease. It can be divided into episodic and chronic subforms based on the number of monthly headache days. Because only a subset of individuals with episodic migraine (EM) progress to chronic migraine (CM) over any given time period, understanding the...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13459

    authors: Buse DC,Greisman JD,Baigi K,Lipton RB

    更新日期:2019-03-01 00:00:00

  • Urinary 6-sulphatoxymelatonin levels are depressed in chronic migraine and several comorbidities.

    abstract:OBJECTIVE:To assess urinary 6-sulphatoxymelatonin levels in a large consecutive series of patients with migraine and several comorbidities (chronic fatigue, fibromyalgia, insomnia, anxiety, and depression) as compared with controls. BACKGROUND:Urine analysis is widely used as a measure of melatonin secretion, as it is...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2009.01547.x

    authors: Masruha MR,Lin J,de Souza Vieira DS,Minett TS,Cipolla-Neto J,Zukerman E,Vilanova LC,Peres MF

    更新日期:2010-03-01 00:00:00

  • The Impact of Shift Work on Migraine: A Case Series and Narrative Review.

    abstract:OBJECTIVE:We present a case report of 2 migraine patients engaged in shift work, followed by a narrative review, to assess whether shift work influences headache-related disability and chronification of migraine. BACKGROUND:Numerous modifiable factors can lead to chronification of migraine and to higher headache-relat...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/head.13622

    authors: Sandoe CH,Sasikumar S,Lay C,Lawler V

    更新日期:2019-10-01 00:00:00

  • Ophthalmoplegia with migraine in adults: is it ophthalmoplegic migraine?

    abstract:OBJECTIVE:Ophthalmoplegic migraine (OM) is a rare disorder characterized by recurrent oculomotor nerve palsy in children, following migraine headaches. We report 62 adults, seen consecutively, who developed acute ophthalmoplegia with severe attacks of migraine over a 10-year (1996-2005) period. An overwhelming majority...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2009.01405.x

    authors: Lal V,Sahota P,Singh P,Gupta A,Prabhakar S

    更新日期:2009-06-01 00:00:00

  • Cushing syndrome induced by serial occipital nerve blocks containing corticosteroids.

    abstract::A patient with chronic daily headaches developed overt signs of Cushing syndrome during treatment with serial occipital nerve block injections. Investigation demonstrated an exogenous source of corticosteroids as the cause of the Cushing syndrome in this patient, thus, implicating the corticosteroid component of the o...

    journal_title:Headache

    pub_type: 杂志文章

    doi:

    authors: Lavin PJ,Workman R

    更新日期:2001-10-01 00:00:00

  • Headache and arachnoid cysts.

    abstract::Arachnoid cysts are commonly encountered when neuroimaging is obtained for headaches. Their clinical relevance is not always immediately clear and they may confound medical management. ...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/head.12415

    authors: Cherian J,Viswanathan A,Evans RW

    更新日期:2014-07-01 00:00:00

  • Olanzapine in the treatment of refractory migraine and chronic daily headache.

    abstract:BACKGROUND:Olanzapine, a thienobenzodiazepine, is a new "atypical" antipsychotic drug. Olanzapine's pharmacologic properties suggest it would be effective for headaches, and its propensity for inducing acute extrapyramidal reactions or tardive dyskinesia is relatively low. We thus decided to assess the value of olanzap...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2002.02126.x

    authors: Silberstein SD,Peres MF,Hopkins MM,Shechter AL,Young WB,Rozen TD

    更新日期:2002-06-01 00:00:00

  • Periaqueductal gray matter dysfunction in migraine: cause or the burden of illness?

    abstract:OBJECTIVE:The periaqueductal gray matter (PAG) is at the center of a powerful descending antinociceptive neuronal network. We studied iron homeostasis in the PAG as an indicator of function in patients with episodic migraine (EM) between attacks and patients with chronic daily headache (CDH) during headache. High-resol...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2001.041007629.x

    authors: Welch KM,Nagesh V,Aurora SK,Gelman N

    更新日期:2001-07-01 00:00:00

  • A review of mechanisms of response to pain therapy: why voodoo works.

    abstract::A person's response to pain treatment may be due to factors other than the direct effect of analgesics. Amelioration of pain is often associated with modalities that appear to make no scientific sense. This review outlines the mechanisms of pain amelioration other than that by medication. These mechanisms help to expl...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2002.02155.x

    authors: Solomon S

    更新日期:2002-07-01 00:00:00

  • Migraine mimics.

    abstract::The symptoms of migraine are non-specific and can be present in many other primary and secondary headache disorders, which are reviewed. Even experienced headache specialists may be challenged at times when diagnosing what appears to be first or worst, new type, migraine status, and chronic migraine. ...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.12518

    authors: Evans RW

    更新日期:2015-02-01 00:00:00

  • Evaluation and treatment of migraine in the emergency department: a review.

    abstract::Head pain is the fifth most common reason for emergency department (ED) visits. It is second only to focal weakness as the most common reason for neurological consultation in the ED. This manuscript reviews how patients with migraine, the most common primary headache disorder for which patients seek medical treatment,...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/head.12399

    authors: Minen MT,Tanev K,Friedman BW

    更新日期:2014-07-01 00:00:00

  • Clinical, anatomical, and physiologic relationship between sleep and headache.

    abstract::The intimate relationship between sleep and headache has been recognized for centuries, yet the relationship remains clinically and nosologically complex. Headaches associated with nocturnal sleep have often been perceived as either the cause or result of disrupted sleep. An understanding of the anatomy and physiology...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2003.03055.x

    authors: Dodick DW,Eross EJ,Parish JM,Silber M

    更新日期:2003-03-01 00:00:00

  • Prevalence of head trauma in patients with difficult headache: the North Norway Headache Study.

    abstract:OBJECTIVE:To test whether chronic headache (>3 days/week) is more prevalent than episodic headache (<3 days/week) in patients with a previous history of significant head trauma. METHOD:We included 903 consecutive patients referred to a specialist center for headache during a period of 2 years. As the main parameter, w...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2003.03010.x

    authors: Bekkelund SI,Salvesen R

    更新日期:2003-01-01 00:00:00

  • Evaluation of beta-endorphin secretion in patients suffering from episodic cluster headache.

    abstract::In order to obtain data regarding peripheral levels of beta-endorphin in head pain syndromes, we evaluated the plasma beta-endorphin secretory pattern in 12 adult male patients suffering from cluster headache. Blood samples were drawn every 2 hours for a 24-hour period, and in addition at 30-minute intervals for 120 m...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.1996.3610603.x

    authors: Franceschini R,Leandri M,Gianelli MV,Cataldi A,Bruno E,Rolandi E,Barreca T

    更新日期:1996-11-01 00:00:00

  • Intravenous lidocaine in the treatment of refractory headache: a retrospective case series.

    abstract:BACKGROUND:New treatments are needed to treat chronic daily headache (CDH) and chronic cluster headache (CCH). New treatments are needed to treat this population and intravenous (IV) lidocaine is a novel treatment for CDH. OBJECTIVE:The aim of this study was to examine the use of IV lidocaine for refractory CDH patien...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2008.01281.x

    authors: Rosen N,Marmura M,Abbas M,Silberstein S

    更新日期:2009-02-01 00:00:00

  • Assessing cortical excitability in migraine: reliability of magnetic suppression of perceptual accuracy technique over time.

    abstract:OBJECTIVES:To examine test-retest reliability of magnetic suppression of perceptual accuracy (MSPA) prior to its use as a marker of cortical excitability in a trial of migraine prophylactic agents. BACKGROUND:MSPA is a relatively novel avenue of research in headache, providing an opportunity to study cortical responsi...

    journal_title:Headache

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1526-4610.2005.00243.x

    authors: Custers A,Mulleners WM,Chronicle EP

    更新日期:2005-10-01 00:00:00

  • Faster Improvement in Migraine Pain Intensity and Migraine-Related Disability at Early Time Points with AVP-825 (Sumatriptan Nasal Powder Delivery System) versus Oral Sumatriptan: A Comparative Randomized Clinical Trial Across Multiple Attacks from the CO

    abstract:BACKGROUND:Fast relief of migraine pain, associated symptoms, and migraine-related disability are priorities in the acute treatment of migraine. Efforts to improve the pharmacokinetic profiles of acute migraine treatments with the aim of providing faster relief include the development of non-oral routes of administrati...

    journal_title:Headache

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/head.13165

    authors: Lipton RB,McGinley JS,Shulman KJ,Wirth RJ,Buse DC

    更新日期:2017-11-01 00:00:00

  • A practice guide for continuous opioid therapy for refractory daily headache: patient selection, physician requirements, and treatment monitoring.

    abstract:OBJECTIVES:To provide a guide to the use and limitations of continuous opioid therapy (COT, or daily scheduled opioids) for refractory daily headache, based on the best available evidence and expert clinical experience. BACKGROUND:There has been a dramatic increase in opioid administration over the past 25 years, with...

    journal_title:Headache

    pub_type: 杂志文章,实务指引,评审

    doi:10.1111/j.1526-4610.2010.01733.x

    authors: Saper JR,Lake AE 3rd,Bain PA,Stillman MJ,Rothrock JF,Mathew NT,Hamel RL,Moriarty M,Tietjen GE

    更新日期:2010-07-01 00:00:00

  • Basilar and middle cerebral artery reactivity in patients with migraine.

    abstract:BACKGROUND:Migraine has been reported as a possible risk factor for ischemic stroke. The mechanisms underlying this association are unknown. OBJECTIVES:To evaluate cerebrovascular reactivity to hypercapnia in the anterior and posterior circulation of patients with migraine, as reduced cerebrovascular reactivity is ass...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2004.04006.x

    authors: Silvestrini M,Baruffaldi R,Bartolini M,Vernieri F,Lanciotti C,Matteis M,Troisi E,Provinciali L

    更新日期:2004-01-01 00:00:00

  • Low dose flunarizine in the prophylaxis of migraine.

    abstract::In a period of one year (1990) we selected 40 patients suffering from migraine. For an open randomized study there were 2 groups of patients: the first were treated with 10mg of flunarizine per day and the second with 3 mg per day. The patients were treated for 4 months consecutively. There were 11 drop outs (27.5%): ...

    journal_title:Headache

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1526-4610.1992.hed3208390.x

    authors: Bassi P,Brunati L,Rapuzzi B,Alberti E,Mangoni A

    更新日期:1992-09-01 00:00:00

  • Prevalence of primary headaches in an urban slum in Enugu South East Nigeria: a door-to-door survey.

    abstract:OBJECTIVE/BACKGROUND:This study aims to determine the prevalence of primary headache disorders using the second edition of international classification of headache disorders among urban slum dwellers. Headache is a common neurological disorder and one of the most common reasons for visiting the neurology clinics in Nig...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.12465

    authors: Ezeala-Adikaibe BA,Onyekonwu C,Okudo G,Onodugo O,Ekenze S,Orjioke C,Chime P,Ezeanosike O,Mbadiwe N,Chikani M,Okwara C,Ulasi I,Ijoma U

    更新日期:2014-11-01 00:00:00

  • Rescue therapy for acute migraine, part 1: triptans, dihydroergotamine, and magnesium.

    abstract:OBJECTIVE:To review and analyze published reports on the acute treatment of migraine headache with triptans, dihydroergotamine (DHE), and magnesium in emergency department, urgent care, and headache clinic settings. METHODS:MEDLINE was searched using the terms "migraine" and "emergency," and "therapy" or "treatment." ...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/j.1526-4610.2011.02062.x

    authors: Kelley NE,Tepper DE

    更新日期:2012-01-01 00:00:00

  • Do Personality Traits Mediate the Relationship Between Childhood Abuse and Migraine? An Exploration of the Relationships in Young Adults Using the Add Health Dataset.

    abstract:BACKGROUND:Personality traits (especially neuroticism) and childhood maltreatment have been independently related to many negative health outcomes later in life, including migraine. Studies have also shown the association between childhood maltreatment and maladaptive personality traits. The mediating role of personali...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13206

    authors: Karmakar M,Elhai JD,Amialchuk AA,Tietjen GE

    更新日期:2018-02-01 00:00:00

  • Repetitive intravenous prochlorperazine treatment of patients with refractory chronic daily headache.

    abstract:OBJECTIVES:To investigate the efficacy and long-term outcome of intravenous prochlorperazine for the treatment of refractory chronic daily headache. BACKGROUND:Unlike dihydroergotamine, the treatment results of intravenous neuroleptics as first-line agents for refractory chronic daily headache have rarely been reporte...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2000.00126.x

    authors: Lu SR,Fuh JL,Juang KD,Wang SJ

    更新日期:2000-10-01 00:00:00

  • Traumatic subarachnoid hemorrhage associated with acupuncture.

    abstract::Subarachnoid hemorrhage as a complication of acupuncture has been reported in only a few cases. We report another case and discuss the implications of subarachnoid hemorrhage following acupuncture. Although acupuncture has traditionally been thought to be relatively safe, physicians should be aware that it may be a ca...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2008.01139.x

    authors: Tsukazaki Y,Inagaki T,Yamanouchi Y,Kawamoto K,Oka N

    更新日期:2008-09-01 00:00:00

  • Headache disability in orofacial pain patients is related to traumatic life events.

    abstract:BACKGROUND:Headache is commonly reported in patients presenting with orofacial pain. It has only recently been demonstrated that headache-related disability is high in orofacial pain patients. Traumatic life events (TLEs) such as sexual abuse, physical abuse, and post-traumatic stress disorder (PTSD) are also common in...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2008.01182.x

    authors: Branch MA

    更新日期:2009-04-01 00:00:00