Expression of neuronal src mRNA as a favorable marker and inverse correlation to N-myc gene amplification in human neuroblastomas.

abstract：:APC10.1 is a new intestinal cell line derived from ApcMin/+ mice that retains both the heterozygous Apc genotype and a nonactivated Wnt signaling pathway and displays an early neoplastic phenotype. Although tumorigenic both in immunodepressed and in immunocompetent syngeneic mice, it requires a high cell dose and a lo...

journal_title：International journal of cancer

authors： De Giovanni C,Landuzzi L,Nicoletti G,Astolfi A,Croci S,Micaroni M,Nanni P,Lollini PL

更新日期：2004-03-20 00:00:00

abstract：:The aim of this study was to construct bispecific F(ab')2 [anti-CD3 x anti-BCL1 idiotype (Id)] Abs (BsAbs) which would enable lymphokine-activated killer (LAK) T cells to kill Id+ mouse BCL1 lymphoma cells, and to determine the mechanism(s) underlying cell death. Using 4-day activated LAK T cells from either perforin-...

journal_title：International journal of cancer

authors： Armstrong JM,Vitetta ES

更新日期：1996-12-11 00:00:00

abstract：:Using comparative genomic hybridisation, we investigated chromosomal imbalances in 28 cases of thymic epithelial neoplasms including type A, B2, B3, the A component of type AB and different subtypes of type C thymoma. To identify different patterns of chromosomal aberrations associated with the biological behaviour an...

journal_title：International journal of cancer

authors： Penzel R,Hoegel J,Schmitz W,Blaeker H,Morresi-Hauf A,Aulmann S,Hecker E,Mechtersheimer G,Otto HF,Rieker RJ

更新日期：2003-07-01 00:00:00

abstract：:The major obstacle for the treatment of gastric cancer is recurrence and metastasis; yet, its molecular mechanism is largely unknown. 2-methoxyestradiol (2-ME), a metabolite of the estradiol-17beta, has recently been demonstrated to have multifactorial effects against tumor proliferation and angiogenesis; how these ef...

journal_title：International journal of cancer

authors： Lin HL,Yang MH,Wu CW,Chen PM,Yang YP,Chu YR,Kao CL,Ku HH,Lo JF,Liou JP,Chi CW,Chiou SH

更新日期：2007-12-01 00:00:00

abstract：:The transcription factor OTX2 has been implicated as an oncogene in medulloblastoma, which is the most common malignant brain tumor in children. It is highly expressed in most medulloblastomas and amplified in a subset of them. To study the role OTX2 has in medulloblastoma we investigated the downstream pathway of OTX...

journal_title：International journal of cancer

authors： Bunt J,Hasselt NE,Zwijnenburg DA,Hamdi M,Koster J,Versteeg R,Kool M

更新日期：2012-07-15 00:00:00

abstract：:Messenger RNA differential display was used to study liver-gene expression in paired tumor and non-tumor tissues from hepatocellular carcinoma (HCC) patients. mRNA differential display and Northern-blot analyses showed that a 0.8-kb cDNA fragment was diminished or absent from the tumorous tissues of 7 HCC patients. Th...

journal_title：International journal of cancer

authors： Chen YM,Shiu JY,Tzeng SJ,Shih LS,Chen YJ,Lui WY,Chen PH

更新日期：1998-03-02 00:00:00

abstract：:Polyclonal and monoclonal antibodies were used to characterize human milk fat globule (HMFG) membrane antigens, using gel filtration, ion exchange chromatography and western blotting. Although originally generated against HMFG, monoclonal antibodies also reacted with skim milk. In western blotting, several antigen mol...

journal_title：International journal of cancer

authors： Ashorn P,Krohn K

更新日期：1985-02-15 00:00:00

abstract：:Dimethylbenzanthracene (DMBA)-induced rat mammary tumors were analyzed for the structure and expression of the oncogenes c-Ha-ras and neu and the effects of anti-estrogen treatment. Tumor samples were divided into 3 groups, the first consisting of untreated tumors, the second of anti-estrogen (toremifene)-treated unre...

journal_title：International journal of cancer

authors： Vuorio T,Wärri A,Sandberg M,Alitalo K,Vuorio E

更新日期：1988-11-15 00:00:00

abstract：:DU-PAN-2 is a high-molecular-weight glycoprotein defined by a murine monoclonal antibody (MAb) against a pancreatic ductal adenocarcinoma cell line. In order to evaluate the usefulness of this antigen as a tumor marker, we determined the serum level of the antigen by competitive inhibition radioimmunoassay in sera fro...

journal_title：International journal of cancer

authors： Sawabu N,Toya D,Takemori Y,Hattori N,Fukui M

更新日期：1986-05-15 00:00:00

abstract：:Using a recently developed autochthonous mouse model of squamous cell carcinoma (SCC), a combination therapy targeting polyamine metabolism was evaluated. The therapy combined 2-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase (ODC), and MQT 1426, a polyamine transport inhibitor. In 1 trial last...

journal_title：International journal of cancer

authors： Chen Y,Weeks RS,Burns MR,Boorman DW,Klein-Szanto A,O'Brien TG

更新日期：2006-05-01 00:00:00

abstract：:A gene product (p42) of the long open reading frame, now termed tax, of the viral genome of human T-cell leukemia virus type I (HTLV-I) may be related to the transformation of T cells in adult T-cell leukemia-lymphoma (ATLL). To evaluate its association with the disease, we compared the prevalence of antibody to p42 i...

journal_title：International journal of cancer

authors： Yokota T,Cho MJ,Tachibana N,McLane MF,Takatsuki K,Lee TH,Mueller N,Essex M

更新日期：1989-06-15 00:00:00

abstract：:We assessed prospectively whether residual cervical intraepithelial neoplasia (CIN) after treatment for high-grade CIN can be predicted by genotype-specific high-risk HPV (HR-HPV) detection in follow-up cervical scrapes. A broad spectrum, highly sensitive SPF(10)-LiPA-PCR HPV detection technique was used on cervical s...

journal_title：International journal of cancer

authors： Bekkers RL,Melchers WJ,Bakkers JM,Hanselaar AG,Quint WG,Boonstra H,Massuger LF

更新日期：2002-11-10 00:00:00

abstract：:Epidemiologic evidence on the association of antioxidant intake and prostate cancer incidence is inconsistent. Total antioxidant intake and prostate cancer incidence have not previously been examined. Using the ferric-reducing antioxidant potential (FRAP) assay, the total antioxidant content (TAC) of diet and suppleme...

journal_title：International journal of cancer

authors： Russnes KM,Wilson KM,Epstein MM,Kasperzyk JL,Stampfer MJ,Kenfield SA,Smeland S,Blomhoff R,Giovannucci EL,Willett WC,Mucci LA

更新日期：2014-03-01 00:00:00

abstract：:In 584 consecutive patients with no previous history of cancer or polypectomy, 769 adenomas were excised endoscopically and classified retrospectively according to the following parameters: macroscopic growth pattern, size, histological type, grade of dysplasia, anatomical site, presence of adenocarcinoma (ADK), numbe...

journal_title：International journal of cancer

authors： Gatteschi B,Costantini M,Bruzzi P,Merlo F,Torcoli R,Nicolo G

更新日期：1991-10-21 00:00:00

abstract：:Nitric oxide may serve as one cofactor for human papillomavirus (HPV)-induced development of cervical cancer. Therefore, we first assessed the levels of cervical fluid nitric oxide metabolite (NOx) in 283 women with and without high-risk (hr) HPV. The NOx level in women with hr HPV (48.4 μmol/L [95% CI: 39.4-56.6], n ...

journal_title：International journal of cancer

authors： Rahkola P,Väisänen-Tommiska M,Tuomikoski P,Ylikorkala O,Mikkola TS

更新日期：2011-06-15 00:00:00

abstract：:Human lymphoblastoid interferon inhibited the growth in vitro of fibroblasts and epithelial cells from normal, hyperplastic and neoplastic human breast tissue. At an interferon concentration of 10(3) inter-national units (IU) per ml, the inhibitory effects on monolayer growth were completely reversible but the growth ...

journal_title：International journal of cancer

authors： Balkwill F,Watling D,Taylor-Papadimitriou J

更新日期：1978-09-15 00:00:00

abstract：:The effects of combined administration of bombesin (40 micrograms/kg body weight) and the ornithine decarboxylase (ODC) inhibitor, 1,3-diaminopropane (DAP), on the development of large and small intestinal tumors and the incidence of their metastasis to the peritoneum induced by azoxymethane (AOM, 7.4 mg/kg body weigh...

journal_title：International journal of cancer

authors： Iishi H,Tatsuta M,Baba M,Uehara H,Nakaizumi A

更新日期：1994-08-15 00:00:00

abstract：:Protein inhibitor of activated signal transducer and activator of transcription 3 (STAT3) (PIAS3) is an endogenous inhibitor of STAT3 that negatively regulates STAT3 transcriptional activity and cell growth and demonstrates limited expression in the majority of human squamous cell carcinomas of the lung. In this study...

journal_title：International journal of cancer

authors： Dabir S,Kluge A,McColl K,Liu Y,Lam M,Halmos B,Wildey G,Dowlati A

更新日期：2014-03-01 00:00:00

abstract：:Ether-linked glycerophospholipids (ether lipids, EL) are selectively toxic and anti-proliferative agents against cancer cells in vitro. The reason for such selectivity is not completely clear. Their mechanism of action is mediated through an interaction with the plasma membrane and the membrane lipid composition may m...

journal_title：International journal of cancer

authors： Diomede L,Piovani B,Modest EJ,Noseda A,Salmona M

更新日期：1991-09-30 00:00:00

abstract：:It is considered that fruit and vegetable (F&V) protect against oesophagus and gastric cancer (GC). However, 2 recent meta-analyses suggest that the strength of association on GC seems to be weaker for vegetables than for fruit and weaker in cohort than in case-control studies. No evidence exists from cohort studies a...

journal_title：International journal of cancer

authors： González CA,Pera G,Agudo A,Bueno-de-Mesquita HB,Ceroti M,Boeing H,Schulz M,Del Giudice G,Plebani M,Carneiro F,Berrino F,Sacerdote C,Tumino R,Panico S,Berglund G,Simán H,Hallmans G,Stenling R,Martinez C,Dorronsoro M

更新日期：2006-05-15 00:00:00

abstract：:Meningioma, the most frequent tumor in the central nervous system, has few recognized risk factors. We explored the role of allergies in a population-based case-control consortium study of meningioma in five geographic areas. We also studied serum levels of a marker of atopic allergy (IgE) in a subset of study partici...

journal_title：International journal of cancer

authors： Wiemels JL,Wrensch M,Sison JD,Zhou M,Bondy M,Calvocoressi L,Black PM,Yu H,Schildkraut JM,Claus EB

更新日期：2011-10-15 00:00:00

abstract：:Elevated plasma lipoprotein(a) has been associated with an increased risk of cardiovascular disease. We report a significant elevation of total plasma apolipoprotein(a) levels in cancer patients compared with hospitalized control patients and normal healthy blood donors. Of the cancer patients studied, 48% had levels ...

journal_title：International journal of cancer

authors： Wright LC,Sullivan DR,Muller M,Dyne M,Tattersall MH,Mountford CE

更新日期：1989-02-15 00:00:00

abstract：:The European Study Group for Pancreatic Cancer (ESPAC-1) study is the largest study of adjuvant treatment for pancreatic ductal adenocarcinoma to date and confirmed a survival advantage for adjuvant chemotherapy but not for chemoradiation. The importance of parallel evaluation of survival and quality of life (QoL) has...

journal_title：International journal of cancer

authors： Carter R,Stocken DD,Ghaneh P,Bramhall SR,Olah A,Kelemen D,Bassi C,Friess H,Dervenis C,Spry N,Büchler MW,Neoptolemos JP,European Study Group for Pancreatic Cancer (ESPAC).

更新日期：2009-06-15 00:00:00

abstract：:BW 5147 lymphoma cells are non-invasive tumor cells which do not generate experimental metastases following i.v. inoculation. In contrast, s.c. and intra-splenic (i.s.) growth of BW cells resulted in widespread colonization of liver and spleen. Cells derived from either s.c. tumors or metastatic lesions did generate m...

journal_title：International journal of cancer

authors： De Baetselier P,Roos E,van Hecke D,Verschaeve L,Brys L,Verschueren H

更新日期：1988-05-15 00:00:00

abstract：:Evidence of the association between chronic inflammation and the risk of colorectal cancer (CRC) and other obesity-related cancers (OBRC) remains inconsistent, possibly due to a paucity of studies examining repeated measures of inflammation. In the Health ABC prospective study of 2,490 adults aged 70-79 years at basel...

journal_title：International journal of cancer

authors： Izano M,Wei EK,Tai C,Swede H,Gregorich S,Harris TB,Klepin H,Satterfield S,Murphy R,Newman AB,Rubin SM,Braithwaite D,Health ABC study.

更新日期：2016-03-01 00:00:00

abstract：:The objective of this study was to assess the utility of a second generation human papillomavirus (HPV) virus-like particle (VLP)-based ELISA as an adjunct to HPV DNA testing to identify women at risk for high-grade cervical intraepithelial neoplasia (CIN). Participants provided blood, cervical samples and interviewer...

journal_title：International journal of cancer

authors： Einstein MH,Studentsov YY,Ho GY,Fazzari M,Marks M,Kadish AS,Goldberg GL,Runowicz CD,Burk RD

更新日期：2007-01-01 00:00:00

abstract：:Condylomata acuminata have been shown to increase the risk of anogenital cancers. However, previous studies have been of limited sample size and/or short follow-up duration, which prevent precise estimates of long-term excess risk, especially for specific cancer sites. We estimated the risk of specific cancers in a la...

journal_title：International journal of cancer

authors： Nordenvall C,Chang ET,Adami HO,Ye W

更新日期：2006-08-15 00:00:00

abstract：:Immunization of mice with 10(6) irradiated LSTRA murine leukemia cells (LX) induced weak immunity to subsequent tumor-cell challenge. Admixture of low doses (1.4-14 micrograms of C. parvum with the LX usually augmented the immunity. Higher doses (1,400-7,000 micrograms) of admixed C. parvum not only failed to augment ...

journal_title：International journal of cancer

authors： Titus MJ,Bartlett GL,Kreider JW

更新日期：1982-06-15 00:00:00

abstract：:In analogy to apoptosis of nucleated cells, erythrocytes may enter eryptosis characterized by cell shrinkage and cell membrane scrambling. Eryptotic erythrocytes are rapidly cleared from circulating blood and may adhere to the vascular wall. Stimulation of eryptosis thus impairs microcirculation and leads to anemia as...

journal_title：International journal of cancer

authors： Lang E,Bissinger R,Qadri SM,Lang F

更新日期：2017-10-15 00:00:00

abstract：:A case-control study of prostate cancer (PC) was undertaken in Athens, Greece. Cases were 320 patients with histologically confirmed incident disease, whereas controls were 246 patients without history or symptomatology of benign prostatic hyperplasia, treated in the same hospitals as the cases for minor diseases or c...

journal_title：International journal of cancer

authors： Hsieh CC,Thanos A,Mitropoulos D,Deliveliotis C,Mantzoros CS,Trichopoulos D

更新日期：1999-03-01 00:00:00