Abstract:
:This is the first report of a series of adults (> 16 years of age) with pineoblastomas who had their entire neuraxis staged at the time of diagnosis. Between 1975 and 1992, seven men and four women with histologically proven pineoblastomas were evaluated at the University of California, San Francisco. The median age at diagnosis was 36 years (range, 17-59 yr). All patients presented with symptomatic hydrocephalus. One patient had a complete surgical resection, eight had subtotal resections, and two had biopsies only. One patient refused any treatment or follow-up review and died 6 months after diagnosis. The five patients with positively staged disease had progression either focally or in the spine 8 to 49 months (median, 10 mo) after initial diagnosis and died 1 to 20 months after recurrence; the median overall survival time from the date of surgery was 30 months. In contrast, all five patients with negatively staged disease were alive without disease progression after a median of 26 months of follow-up. Our retrospective review shows that the extent of disease at diagnosis seems to be an important prognostic factor for pineoblastomas, as is true for medulloblastomas and other primitive neuroectodermal tumors. Initial staging should include examination of the cerebrospinal fluid and magnetic resonance imaging of the spine. Although patients with pineoblastomas are often treated with adjuvant systemic chemotherapy after craniospinal irradiation, the benefits of this approach are unclear.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Chang SM,Lillis-Hearne PK,Larson DA,Wara WM,Bollen AW,Prados MDdoi
10.1227/00006123-199509000-00003subject
Has Abstractpub_date
1995-09-01 00:00:00pages
383-90; discussion 390-1issue
3eissn
0148-396Xissn
1524-4040journal_volume
37pub_type
杂志文章相关文献
NEUROSURGERY文献大全abstract::Magnetic resonance neurography was used to directly image cervical spinal nerves in patients with clinical and radiographic evidence of cervical radiculopathy. A magnetic resonance imaging phased-array coil system was used to obtain high-resolution coronal T1-weighted spin echo, coronal/axial T2-weighted fast spin ech...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199603000-00013
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:Spine stereotactic body radiotherapy (sSBRT) is commonly limited to 1 or 2 vertebral levels given a paucity of efficacy and toxicity data when more than 2 levels are treated. OBJECTIVE:To prove our hypothesis that multilevel sSBRT could provide similar rates of local control (LC) (primary endpoint) and toxi...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyz348
更新日期:2020-02-01 00:00:00
abstract::A case of postoperative tension pneumocephalus of unusual cause after carotid-ophthalmic artery aneurysm clipping is presented. A second craniotomy for decompression and exploration demonstrated a small fistula in the planum sphenoidale, which presumably had been made when the right optic canal was unroofed during the...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/00006123-198811000-00020
更新日期:1988-11-01 00:00:00
abstract::A newly designed cottonoid is fixed to the tip of the suction device by the negative pressure. It is especially useful during microsurgical procedures in areas crowded with neurovascular elements. The advantage of pressure-mounted cottonoids lies in the protection provided to the brain and neurovascular elements durin...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-198212000-00010
更新日期:1982-12-01 00:00:00
abstract::Local steroid injections for symptomatic relief of carpal tunnel syndrome have become common in the evaluation and treatment of this disorder; yet reports of median nerve injection injury from this practice are rare. We present a case of nerve injury from a steroid injection in a 24-year-old man with carpal tunnel syn...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199003000-00021
更新日期:1990-03-01 00:00:00
abstract:BACKGROUND:Although real-time localization of gliomas has improved with intraoperative image guidance systems, these tools are limited by brain shift, surgical cavity deformation, and expense. OBJECTIVE:To propose a novel method to perform near-infrared (NIR) imaging during glioma resections based on preclinical and c...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0000000000001450
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Resection is a critical component in the initial treatment of glioblastoma (GBM). Often GBMs are resected using an intralesional method. Circumferential perilesional resection of GBMs has been described, but with limited data. OBJECTIVE:To conduct an observational retrospective analysis to test whether peri...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyz008
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:The most frequent embryonic communication between the vertebrobasilar and carotid systems is a persistent trigeminal artery (PTA). It has been observed in 0.1 to 0.2% of cerebral angiograms. We found this variation in an anatomic specimen, and after microscopic dissection, we performed an analysis of the c...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199809000-00082
更新日期:1998-09-01 00:00:00
abstract::Although thrombocytopenia occurs in approximately 10% of medical patients who receive heparin, this complication has not been described in neurosurgical patients. We report the clinical course of two patients who in the immediate postoperative period developed heparin-associated thrombocytopenia that resulted in signi...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198607000-00010
更新日期:1986-07-01 00:00:00
abstract::The incidence of intracerebral hematomas after myocardial infarction increases after thrombolysis. As noted in the case described, clots formed after the administration of thrombolytic agents may remain liquid, and this blood can be drained by a catheter. However, in this case, the patient continued to bleed locally. ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199311000-00019
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVE:The statement that intracranial meningiomas are cleavable tumors has to be seriously questioned from a surgical standpoint. The purpose of this study was 1) to analyze the operative reports of a personal series of meningiomas to evaluate the percentages of the tumors that could be dissected by passing in the ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199803000-00007
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:An excruciating headache of instantaneous onset is known as a thunderclap headache. A subarachnoid hemorrhage is the prototypical cause, but other serious disorders may also present with a thunderclap headache, including cerebral venous sinus thrombosis, carotid artery dissection, and pituitary apoplexy. We r...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-200103000-00009
更新日期:2001-03-01 00:00:00
abstract:OBJECTIVE:Although the necessity of craniotomy for an unruptured cerebral aneurysm (UCA) is controversial, surgery is warranted if surgical risks are less than the risks of natural history. In this study, we investigated the need for craniotomy for UCAs on the basis of surgical risk. METHODS:History of cerebrovascular...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000148897.28828.85
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:To determine the indications for, efficacy of, and safety of depth electrode placement using magnetic resonance imaging (MRI)-guided stereotactic surgery in patients with intractable epilepsy. METHODS:We analyzed retrospectively the results of depth electrode usage in 50 consecutive patients at the Universit...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1097/00006123-199608000-00018
更新日期:1996-08-01 00:00:00
abstract::Having encountered a number of thick-walled or mobile symptomatic intracranial cysts that have resisted stereotactic puncture with standard blunt-ended ventricular catheters, the authors have designed a cyst puncture catheter that has a number of features helpful in overcoming this problem. The catheter and its use ar...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:An intracranial aneurysm is an important acquired cerebrovascular disease that can cause a catastrophic subarachnoid hemorrhage. Despite modern therapy, most patients die or are left disabled as a direct result of a severe initial hemorrhage. The development of more effective treatment strategies depends on u...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199911000-00024
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVE:To compare the effectiveness of the telovelar approach with tonsillar manipulation for approaching the recesses of the fourth ventricle. METHODS:A telovelar approach was performed in 8 injected cadaveric heads. Areas of exposure were measured for the superolateral and lateral recesses. Horizontal angles were...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000348558.35921.4E
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Although the combined petrosal approach has significant advantages for medium to large petroclival lesions, it carries the risk of a few major complications. The cerebrospinal fluid leak rate with this approach has been reported to be as high as 15%. OBJECTIVE:To describe an innovative technique of watertig...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/NEU.0b013e3182356269
更新日期:2012-06-01 00:00:00
abstract::Arterial stenoses and/or occlusions in moyamoya disease are mainly localized intracranially, although some instances of stenotic lesions of the extracranial arteries have been reported in some autopsy cases. We have reviewed the angiograms of 66 patients with moyamoya disease to investigate whether stenotic lesions ar...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199209000-00002
更新日期:1992-09-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:Four rare cases of central nervous system solitary fibrous tumors (C-SoFTs) are described. This tumor has not previously been reported in children or in deep cortical structures. Three of these tumors occurred in the posterior fossa. Only four cases in the posterior fossa have been described pr...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000115675.74366.87
更新日期:2004-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the effect of early optic canal unroofing on visual function in patients with meningiomas of the tuberculum sellae and planum sphenoidale. METHODS:We retrospectively reviewed the clinical records of 20 consecutive patients with tuberculum sellae meningiomas and two patie...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000318169.75095.cb
更新日期:2008-04-01 00:00:00
abstract::Ten patients with giant intradural spinal arteriovenous fistulas (perimedullary Types II and III) were treated with embolization alone (three patients) or in combination with surgery (seven patients). Their ages at the time of treatment ranged from 2 to 40 years, with a mean of 19.5 years. The indications for treatmen...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199312000-00003
更新日期:1993-12-01 00:00:00
abstract::The recently described multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 (MTS1/CDKN2) gene, encoding the cyclin-dependent kinase 4 inhibitor p16, is mutated in a wide variety of tumor cell lines, including gliomas. To investigate the possible role of this gene in the genesis of the central nervous system...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199505000-00013
更新日期:1995-05-01 00:00:00
abstract::The diagnosis of malignant glioma of the optic nerves and chiasm may be difficult because these rare lesions may mimic other suprasellar lesions. We report a case of glioblastoma multiforme of the optic chiasm in which the appearance of the lesion on computed tomographic (CT) scan was consistent with that of craniopha...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198212000-00011
更新日期:1982-12-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:Two patients with vertebrobasilar dolichoectasia sustained massive fatal subarachnoid hemorrhage from rupture of the basilar artery wall. Hemorrhage from this entity is not widely known to occur during its natural history and may be exacerbated by systemic anticoagulation. CLINICAL PRESENTATIO...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199802000-00108
更新日期:1998-02-01 00:00:00
abstract::This retrospective review of pediatric patients with pituitary tumors causing onset of symptoms by 17 years of age was done to define their pathological distribution, clinical presentation, treatment, and prognosis. Eighteen patients were evaluated and treated from 1979 to 1989. Five had Cushing's disease and 13 had p...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199110000-00004
更新日期:1991-10-01 00:00:00
abstract::Intracranial cartilaginous tumors are unusual lesions, of which myxoid chondrosarcoma is the rarest. We describe this tumor arising from the falx in a 28-year-old woman treated at recurrence with a second operation and a radiation implant. The behavior of classic chondrosarcoma and mesenchymal chondrosarcoma is also r...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199208000-00021
更新日期:1992-08-01 00:00:00
abstract:BACKGROUND:Aneurysmal subarachnoid hemorrhage (aSAH) is associated with disproportionally high mortality and long-term neurological sequelae. Management of patients with aSAH has changed markedly over the years, leading to improvements in outcome. OBJECTIVE:To describe trends in aSAH care and outcome in a high-volume ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyaa465
更新日期:2020-12-11 00:00:00
abstract::Visual field abnormalities were studied in a retrospective analysis of 199 patients with epidural hematomas. One hundred three patients had been alert enough at the time of hospital admission to have had their visual fields examined, but in only 27 patients were visual fields documented in the charts. Six of the 27 pa...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198208000-00007
更新日期:1982-08-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:Traditionally, thoracic fractures that require anterior stabilization are treated through an open thoracotomy approach. Thoracoscopic instrumentation avoids many of the complications associated with an open thoracotomy but is technically challenging. We report the first cases of dual-rod intern...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000119229.92157.66
更新日期:2004-05-01 00:00:00