Abstract:
OBJECTIVE:An excruciating headache of instantaneous onset is known as a thunderclap headache. A subarachnoid hemorrhage is the prototypical cause, but other serious disorders may also present with a thunderclap headache, including cerebral venous sinus thrombosis, carotid artery dissection, and pituitary apoplexy. We report a group of patients with thunderclap headaches as the initial manifestation of spontaneous intracranial hypotension caused by a spinal cerebrospinal fluid leak. METHODS:Among 28 patients with spontaneous intracranial hypotension due to a documented spinal cerebrospinal fluid leak, four (14%) initially experienced an excruciating headaches of instantaneous onset. RESULTS:The mean age of the four patients (two men and two women) was 35 years (range, 24-45 yr). Nuchal rigidity was present in the three patients who sought early medical attention, and they underwent emergency computed tomographic scanning, lumbar puncture, and cerebral angiography to rule out an aneurysmal subarachnoid hemorrhage. The delay between the onset of headache and diagnosis of intracranial hypotension ranged from 4 days to 5 weeks. A fourth patient did not seek medical attention until 1 month after the ictus. CONCLUSION:Spontaneous intracranial hypotension should be included in the differential diagnosis of thunderclap headache, even when meningismus is present.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Schievink WI,Wijdicks EF,Meyer FB,Sonntag VKdoi
10.1097/00006123-200103000-00009keywords:
subject
Has Abstractpub_date
2001-03-01 00:00:00pages
513-6; discussion 516-7issue
3eissn
0148-396Xissn
1524-4040journal_volume
48pub_type
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