当前位置： SCI文献检索 > NEUROSURGERY期刊下所有文献 > Morbidity and mortality from surgical treatment of unruptured cerebral aneurysms at Research Institute for Brain and Blood Vessels-Akita.

Morbidity and mortality from surgical treatment of unruptured cerebral aneurysms at Research Institute for Brain and Blood Vessels-Akita.

Abstract：

OBJECTIVE:Although the necessity of craniotomy for an unruptured cerebral aneurysm (UCA) is controversial, surgery is warranted if surgical risks are less than the risks of natural history. In this study, we investigated the need for craniotomy for UCAs on the basis of surgical risk. METHODS:History of cerebrovascular disorders, aneurysm site and size, surgical complications, and clinical outcome were investigated in 368 patients (134 men, 234 women; ages 31-79 yr) who underwent craniotomy for treatment of UCA at our institute between 1993 and 2000. RESULTS:We investigated 549 aneurysms. The mean size was 6.0 mm. Sites affected were the anterior cerebral artery (101 aneurysms), internal carotid artery (224 aneurysms), middle cerebral artery (201 aneurysms), and vertebrobasilar artery (23 aneurysms). The most common previous cerebrovascular disorders were subarachnoid hemorrhage (58 patients, 15.8%) and cerebral infarction (41 patients, 11.1%). Eight patients experienced permanent neurological deficits, for a total morbidity of 2.2%. One patient died, for a total mortality of 0.3%. For UCAs less than 10 mm in size, the morbidity was 0.6% and the mortality was 0%. For UCAs greater than 10 mm in size, the morbidity was 6.1% and the mortality was 1.2%. For UCAs in the anterior cerebral artery or middle cerebral artery, the morbidity was 0.3%. Temporary deficits were more frequently observed in patients older than 70 years of age than in patients 70 years of age or less. CONCLUSION:Surgical treatment is a viable alternative for patients 70 years of age or less with UCAs less than 10 mm in size or UCAs located in the anterior cerebral artery or middle cerebral artery, because the surgical risk of treating such UCAs is sufficiently lower than the annual rupture rate of UCAs (2.3%) and the mental stress suffered by patients with untreated UCAs.

journal_name

Neurosurgery

journal_title

Neurosurgery

authors

Moroi J,Hadeishi H,Suzuki A,Yasui N

doi

10.1227/01.neu.0000148897.28828.85

keywords:

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

224-31; discussion 224-31

issue

eissn

0148-396X

issn

1524-4040

journal_volume

pub_type

杂志文章

在线工具

Morbidity and mortality from surgical treatment of unruptured cerebral aneurysms at Research Institute for Brain and Blood Vessels-Akita.