Effects of sex hormone binding globulin capacity and pregnancy zone protein of treatment with combinations of ethinyl-oestradiol and norethisterone.

abstract：PURPOSE:The aim of this study was to investigate the putative changes in serum angiotensinase activities (aminopeptidase N, APN; aminopeptidase B, APB; aminopeptidase A, APA; aspartyl aminopeptidase, ASAP) involved in the renin-angiotensin system (RAS) in women with breast cancer treated or not with a neoadjuvant thera...

journal_title：Maturitas

authors： Ramírez-Expósito MJ,Carrera-González Mdel P,Mayas MD,Dueñas B,Martínez-Ferrol J,Martínez-Martos JM

更新日期：2012-05-01 00:00:00

abstract：:Although age is the most crucial predictor of a woman's reproductive capacity, it is assumed that there is still a risk of pregnancy in menopause transition, as occasional spontaneous ovulation is possible. Moreover, age alone is not sufficient to contraindicate the use of any contraceptive method, whether hormonal or...

journal_title：Maturitas

authors： Mendoza N,Sanchez-Borrego R

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study is to determine if the depression in perimenopausal women is symptomatologically different than depression in premenopausal women, and if these depressive women are under more risk for depression when factors like premenstrual dysphoric syndrome, socio-economical status, vasomotor sympt...

journal_title：Maturitas

authors： Oztürk O,Eraslan D,Mete HE,Ozşener S

更新日期：2006-09-20 00:00:00

abstract：OBJECTIVE:To re-examine the minimal effective dose of conjugated estrogen (CEE)-progestin hormone replacement on postmenopausal bone loss. DESIGN:A 2-year, prospective, open label, randomized study. SETTING:Department of Obstetrics and Gynecology of a university hospital. PARTICIPANTS:Fifty-two postmenopausal or oop...

journal_title：Maturitas

authors： Mizunuma H,Okano H,Soda M,Kagami I,Miyamoto S,Tokizawa T,Honjo S,Ibuki Y

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:New regimens and routes of administration of hormonal replacement therapy (HRT) in climateric women are becoming available. Since there is no information on the neuroendocrine effects of sequential combined treatment with 17 beta-estradiol and a progestin, the present study evaluated the neuroendocrine, clini...

journal_title：Maturitas

authors： Stomati M,Bersi C,Rubino S,Palumbo M,Comitini G,Genazzani AD,Santuz M,Petraglia F,Genazzani AR

更新日期：1997-12-15 00:00:00

abstract：:Fifty-six premenopausal women were drawn from a cross-sectional survey of 850 women living in South-East England. They were recontacted 3 years later when 36 met the criterion of being naturally peri- or postmenopausal. Somatic, vasomotor and emotional symptoms, as well as general health, use of medical services and b...

journal_title：Maturitas

authors： Hunter M

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Participation in regular physical activity is among the most promising and cost effective strategies to reduce physical and cognitive decline and premature death. However, confusion remains about the amount, frequency, and duration of physical activity that is likely to provide maximum benefit as well as the...

journal_title：Maturitas

authors： Anderson D,Seib C,Rasmussen L

更新日期：2014-09-01 00:00:00

abstract：:The synthetic progestins used so far for contraception and menopausal hormone therapy are derived either from testosterone (19-nortestosterone derivatives) or from progesterone (17-OH progesterone derivatives and 19-norprogesterone derivatives). Among the 19-nortestosterone derivatives, the estrane group include noret...

journal_title：Maturitas

authors： Sitruk-Ware R

更新日期：2004-04-15 00:00:00

abstract：OBJECTIVES:Menopausal status is a common covariate in epidemiologic studies. Still, there are no standard definitions for menopausal status using observational data. This study assesses distinctions between menopausal status definitions using commonly collected epidemiologic data, and explores their impact on study out...

journal_title：Maturitas

authors： Phipps AI,Ichikawa L,Bowles EJ,Carney PA,Kerlikowske K,Miglioretti DL,Buist DS

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVES:It is still controversial whether hormone replacement therapy (HRT) can affect the onset of uterine myomas or their growth in postmenopause. It is likely that some therapeutic schedules can influence the myometrial growth differently, due to a more potent stimulation of the uterine receptors. The aim of the ...

journal_title：Maturitas

authors： Polatti F,Viazzo F,Colleoni R,Nappi RE

更新日期：2000-11-30 00:00:00

abstract：BACKGROUND:Leydig cell tumours of the ovary are very rare benign neoplasms, frequently associated with symptoms of virilisation, in postmenopausal patients. Only four cases of bilateral Leydig tumours have been reported in the literature. CASE REPORT:We report an additional case of bilateral presentation. A 77-year-ol...

journal_title：Maturitas

authors： Sanz OA,Martinez PR,Guarch RT,Goñi MJ,Alcazar JL

更新日期：2007-06-20 00:00:00

abstract：PURPOSE:Traditionally, general practitioners (GPs) are not involved in cancer-related treatment decisions, despite their often long relationship with patients, and their unique position to explore patients' values, especially with older patients. Therefore, we designed a randomised controlled trial to study the effect,...

journal_title：Maturitas

authors： Stegmann ME,Schuling J,Hiltermann TJ,Reyners AK,Burger H,Berger MY,Berendsen AJ

更新日期：2017-02-01 00:00:00

abstract：:The incidence of breast cancer has continued to decrease each year at Wilford Hall United States Air Force Medical Center with the ever-increasing use of combined progestogen-oestrogen replacement therapy over the past 12 yr. By 1983, the overall incidence of breast cancer had fallen to 53.9:100 000. The lowest rate f...

journal_title：Maturitas

authors： Gambrell RD Jr

更新日期：1986-07-01 00:00:00

abstract：OBJECTIVES:Association studies between estrogen receptor alpha (ERalpha) gene polymorphisms and bone mineral density (BMD) have yielded inconsistent results. In the present study we evaluated the influence of XbaI and PvuII ERalpha gene polymorphisms on BMD, biochemical markers, rates of bone loss and the response to e...

journal_title：Maturitas

authors： Rapuri PB,Gallagher JC,Knezetic JA,Haynatzka V

更新日期：2006-03-20 00:00:00

abstract：OBJECTIVES:To describe the characteristics, metabolic control and health-related quality of life (HRQL) of type 2 diabetes mellitus (T2DM) geriatric patients. STUDY DESIGN:Cross-sectional descriptive study of consecutive patients attended at a geriatric outpatient clinic in a tertiary hospital over three months. Socio...

journal_title：Maturitas

authors： Rodríguez-Pascual C,Rodriguez-Justo S,García-Villar E,Narro-Vidal M,Torrente-Carballido M,Paredes-Galan E

更新日期：2011-08-01 00:00:00

abstract：:Forty-five healthy postmenopausal women participated in a study designed to examine the effects on bone and mineral metabolism of SHD 386L, a new hormone replacement therapy (HRT) regime. This oral preparation delivers 2 mg estradiol valerate daily and 75 micrograms of levonorgestrel from days 17-28 inclusive of a 28-...

journal_title：Maturitas

authors： Purdie DW,Hay AW,Everett M

更新日期：1992-03-01 00:00:00

abstract：:Epidemiological studies have shown that cigarette smoking is associated with an increased risk of midlife hot flashes; however, the effect of quitting smoking on this risk is unclear. The purpose of this study was to examine the effect of quitting smoking on hot flashes using data from 761 women aged 45 to 54 years of...

journal_title：Maturitas

authors： Smith RL,Flaws JA,Gallicchio L

更新日期：2015-09-01 00:00:00

abstract：:It is hypothesized that chronic systemic inflammation contributes to the age-related decline in cardiovascular function. The aim of the present study was to combine an assessment of the relationship between the serum level of C-reactive protein (CRP) and systolic and diastolic blood pressure in 108 elderly women (65 a...

journal_title：Maturitas

authors： Hosford-Donovan A,Nilsson A,Wåhlin-Larsson B,Kadi F

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:This paper aims to report the methodology of a study of a cohort of middle-aged women in Taiwan, their age at menopause, and related factors and prevalence of menopausal symptoms, and to examine the relationships between symptoms and sociodemographic variables. METHODS:An epidemiological study of neuropsych...

journal_title：Maturitas

authors： Fuh JL,Wang SJ,Lu SR,Juang KD,Chiu LM

更新日期：2001-08-25 00:00:00

abstract：:Stroke represents one of the most important menaces to public health. A number of modifiable and non-modifiable risk factors have been identified and studied in detail; among those, obesity, the new world epidemic, seems to be one of the most important in terms of prevention. The discovery of the secretory role of the...

journal_title：Maturitas

authors： Savopoulos C,Michalakis K,Apostolopoulou M,Miras A,Hatzitolios A

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVES:To better define the longitudinal changes in renal function, to examine the associated risk factors, and to investigate whether there is an independent association of decline in renal function with presence of carotid plaque in a middle-aged and elderly healthy population. METHODS:245 healthy individuals (9...

journal_title：Maturitas

authors： Jiang S,Sun X,Gu H,Chen Y,Xi C,Qiao X,Chen X

更新日期：2012-11-01 00:00:00

abstract：:A prospective study was conducted amongst Hong Kong Chinese women to determine the incidence of acute menopausal symptoms following surgical menopause. Cases where a laparotomy was performed for other indications were used as controls. Hot flushes and sweating developed in 8/33 (24.2%) and 6/33 (18.2%), respectively, ...

journal_title：Maturitas

authors： Haines CJ,Chung TK,Leung DH

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:With the significant improvement of the cure rate and survival rate of cancer patients, the survivors face quality-of-life problems, such as a significant decline in reproductive system development, ovarian reserves and function, and even fertility loss and early menopause. These problems are often highly as...

journal_title：Maturitas

authors： Zhang J,Ma X,Li Y,Liu R,Li Y,Zhang P,Ren W,Cui P,Wang B,Zhang M,Jin Y,Li X,Wang S

更新日期：2020-07-01 00:00:00

abstract：:Estrogen is a well-known mitogen in human breast epithelium but the action of progestogen is complex and incompletely understood. During the last years, accumulating data from animal, clinical and observational studies suggest a proliferative effect in breast tissue when progestogen is added to estrogen. Findings in s...

journal_title：Maturitas

authors： Söderqvist G,von Schoultz B

更新日期：2004-09-24 00:00:00

abstract：OBJECTIVES:Vaginal atrophy (VA) is a chronic medical condition. It is managed unsatisfactorily, despite its high prevalence and negative impact on female quality of life. In order to meet their needs, it would be useful to know what women perceive to be the most bothersome symptom (MBS) of VA. STUDY DESIGN:Cross-secti...

journal_title：Maturitas

authors： Palma F,Xholli A,Cagnacci A,as the writing group of the AGATA study.

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:Strategies in case of high risk of breast cancer in BRCA1/2 mutation carriers are either intensive breast cancer screening or risk-reducing mastectomy (RRM). Both options have a high physical and psychosexual impact. The aim of this study is to investigate who chooses when to undergo RRM. METHODS:BRCA1/2 ...

journal_title：Maturitas

authors： van Driel CM,Eltahir Y,de Vries J,Jaspers JP,Oosterwijk JC,Mourits MJ,de Bock GH

更新日期：2014-02-01 00:00:00

abstract：:It is widely recognised that women's sexuality can be particularly complex after breast cancer, with sexual changes often becoming the most problematic aspect of a woman's life. The impact of such changes can last for many years after successful treatment, and can be associated with serious physical and emotional side...

journal_title：Maturitas

authors： Gilbert E,Ussher JM,Perz J

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVES:This paper examines the evidence supporting testosterone replacement in aging males. Confounding factors contributing to low testosterone levels and challenges to diagnosis of the andropause will also be considered. METHODS:A thorough review using an integrative approach citing published literature and the ...

journal_title：Maturitas

authors： Tan RS,Culberson JW

更新日期：2003-05-30 00:00:00

abstract：OBJECTIVE:Social support interventions for caregivers of persons with dementia (PwD) are important because informal carers often rely on their social networks for support. This systematic review synthesises findings from research on social support interventions, and examines their methodological quality and effectivene...

journal_title：Maturitas

authors： Dam AE,de Vugt ME,Klinkenberg IP,Verhey FR,van Boxtel MP

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:To review some aspects in the recent literature related to the effects of postmenopausal estrogen and progestin use on major plasma lipoprotein risk factors for coronary heart disease (CHD). METHODS:Collection of relevant information from medical journals, and by the use of Medline and Current Contents. RE...

journal_title：Maturitas

authors： Tikkanen MJ

更新日期：1996-05-01 00:00:00