Urinary prostaglandins following frusemide treatment and salt depletion in normal subjects and subjects with diabetic hyporeninaemic hypoaldosteronism.

abstract：OBJECTIVE:Thyroid cancer is the most common malignant endocrine tumour, and its incidence has continuously increased worldwide over the past three decades. We focused on the association of multifocal papillary thyroid carcinoma (PTC) with messenger RNA (mRNA) expression to characterize how molecular and histopathologic...

journal_title：Clinical endocrinology

authors： Pak K,Suh S,Goh TS,Kim SJ,Oh SO,Seok JW,Kim IJ,Kim YH

更新日期：2019-04-01 00:00:00

abstract：:Osmoregulation of vasopressin release and thirst was studied in the mid-follicular and mid-luteal phases of the menstrual cycle of five patients with cyclical oedema defined by peripheral oedema and weight gain (greater than 3.0 kg) manifest in two consecutive luteal phases. Results are compared to those already obtai...

journal_title：Clinical endocrinology

authors： Thompson CJ,Burd JM,Baylis PH

更新日期：1988-06-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between circulating leptin levels, bone mineral content and density in the elderly. DESIGN:A cross-sectional study. PATIENTS:A cohort of 92 men and 171 women, with ages ranging from 68 to 75 years, selected as a healthy and normal functioning group, in the city centre of Verona. ...

journal_title：Clinical endocrinology

authors： Zoico E,Zamboni M,Adami S,Vettor R,Mazzali G,Tosoni P,Bissoli L,Bosello O

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:Low growth hormone (GH) secretion and hypogonadism are common in patients with Prader-Willi syndrome (PWS). In this study we present the effects of GH treatment on body composition and metabolism in adults with PWS. PATIENTS AND MEASUREMENTS:Nineteen patients with clinical PWS were recruited, 13 had PWS geno...

journal_title：Clinical endocrinology

authors： Höybye C,Hilding A,Jacobsson H,Thorén M

更新日期：2003-05-01 00:00:00

abstract：:A 47-year-old woman was evaluated for congenital dwarfism, primary amenorrhoea due to hypogonadotrophic hypogonadism, severe hyperlipidaemia with pancreatitis, and overt diabetes mellitus associated with severe insulin resistance requiring 2.5-3 units of insulin per kilogram body weight. Chromosomal analysis with tryp...

journal_title：Clinical endocrinology

authors： Mantzoros CS,Moses AC

更新日期：1995-08-01 00:00:00

abstract：DESIGN:Prevalence of type 2 diabetes and glucose intolerance increase with age. It has been demonstrated that beta cell function declines at about 1% per year in glucose tolerant Caucasians. However, this relationship is not known to exist in other ethnic groups. SUBJECTS AND MEASUREMENTS:We investigated the relations...

journal_title：Clinical endocrinology

authors： Chiu KC,Martinez DS,Chu A

更新日期：2005-03-01 00:00:00

abstract：:The ultrastructural effects of a Leydig cell tumour of the testis on nontumorous testicular tissue have not yet been reported. Described here are the electron microscopic findings in the nonneoplastic testicular tissue of a patient with a feminizing testicular Leydig cell neoplasm. Serial studies were carried out over...

journal_title：Clinical endocrinology

authors： Sohval AR,Churg J,Suzuki Y,Katz N,Gabrilove JL

更新日期：1977-02-01 00:00:00

abstract：OBJECTIVE:The aim was to study the relationship between growth hormone (GH) and insulin-like growth factor-I (IGF-I) in critically ill patients. DESIGN:Case-control study of critically ill patients admitted to the intensive care unit was carried out. PATIENTS:Six critically ill patients (51-78 years) who required ven...

journal_title：Clinical endocrinology

authors： Ross R,Miell J,Freeman E,Jones J,Matthews D,Preece M,Buchanan C

更新日期：1991-07-01 00:00:00

abstract：INTRODUCTION:Prader-Willi syndrome (PWS) is a genetic disorder caused by the loss of expression of paternally transcribed genes in a highly imprinted region of chromosome 15q11-13. The clinical phenotype has been well characterized, mostly related to hypothalamic dysfunction. Even though central hypothyroidism has been...

journal_title：Clinical endocrinology

authors： Vaiani E,Herzovich V,Chaler E,Chertkoff L,Rivarola MA,Torrado M,Belgorosky A

更新日期：2010-10-01 00:00:00

abstract：:There is evidence that the porcine TSH receptor contains essential disulphide bridge(s) which can be disrupted by dithiothreitol (DTT). The aim of the present study was to determine whether exposure of intact thyroid cells to DTT leads to altered thyroid stimulation. TSH-stimulated iodine organification in cultured po...

journal_title：Clinical endocrinology

authors： Ginsberg J,Rafter DJ,von Westarp C,Murray PG

更新日期：1987-04-01 00:00:00

abstract：:In order to evaluate the possible influence of GABAergic neurotransmission on the arginine vasopressin (AVP) response to osmotic and pressure volumetric stimuli, the GABAergic drug sodium valproate was administered by mouth (200 or 400 mg 16 h, 8 h and just before tests) to eight normal men before osmotic (i.v. infusi...

journal_title：Clinical endocrinology

authors： Chiodera P,Gnudi A,Volpi R,Marchesi C,Marchesi M,Davoli D,Capretti L,Coiro V

更新日期：1989-04-01 00:00:00

abstract：:Sleep history and pituitary function were studied and sleep polygraphy performed in 11 acromegalic patients before and after pituitary surgery. Excessive daytime sleepiness or habitual snoring or both together, as well as an elevated fasting level of serum GH occurred in all the patients. In five men but in none of th...

journal_title：Clinical endocrinology

authors： Pekkarinen T,Partinen M,Pelkonen R,Iivanainen M

更新日期：1987-12-01 00:00:00

abstract：:A single fasting level of serum prolactin was measured in each of sixty control subjects and eighty-three psychiatric patients of both sexes who had been on neuroleptic therapy for 2-4 weeks (acute treatment) or at least 5 years (chronic treatment) and who were aged either 17-45 or 48-85 years. All groups of patients ...

journal_title：Clinical endocrinology

authors： Rivera JL,Lal S,Ettigi P,Hontela S,Muller HF,Friesen HG

更新日期：1976-05-01 00:00:00

abstract：:The effect of pretreatment with biosynthetic methionyl human GH (hGH) on the GH response to GHRH has been studied in normal subjects. Eight volunteers were given either 4 IU hGH or placebo s.c. 12-hourly for 72 h before a GHRH test, or a single s.c. dose of 4 IU hGH 12 h before a GHRH test. Somatomedin-C (Sm-C) levels...

journal_title：Clinical endocrinology

authors： Ross RJ,Borges F,Grossman A,Smith R,Ngahfoong L,Rees LH,Savage MO,Besser GM

更新日期：1987-01-01 00:00:00

abstract：:We report a patient with unilateral thyroid carcinoma, who developed hyperfunction of the thyroid gland during the metastatic progression of the thyroid carcinoma. Concurrently with this event, TSI increased and it is suggested that the differentiated aggressive metastatic thyroid neoplasm had initiated the autoimmune...

journal_title：Clinical endocrinology

authors： Steffensen FH,Aunsholt NA

更新日期：1994-11-01 00:00:00

abstract：:In a prospective controlled trial we investigated the effect of an induction dose of etomidate (0.26 mg/kg i.v.) on plasma ACTH, progesterone, 17 alpha OH-progesterone, 11-deoxycortisol, cortisol, cortisone, corticosterone, 11-deoxycorticosterone, and aldosterone in seven males undergoing general anaesthesia. Seven ot...

journal_title：Clinical endocrinology

authors： Allolio B,Dörr H,Stuttmann R,Knorr D,Engelhardt D,Winkelmann W

更新日期：1985-03-01 00:00:00

abstract：CONTEXT:Germline mutations in four genes (RET, VHL, SDHB and SDHD) are detected in about 17% of patients with apparently sporadic pheochromocytoma. Thus, genetic screening of all patients with this disease is suggested for a rational diagnostic approach and management. OBJECTIVE:To report the clinical, biochemical and...

journal_title：Clinical endocrinology

authors： D'Elia AV,Grimaldi F,Pizzolitto S,De Maglio G,Bregant E,Passon N,Franzoni A,Verrienti A,Tamburrano G,Durante C,Filetti S,Fogolari F,Russo D,Damante G

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to address the effect of endurance training on monocyte glucocorticoid sensitivity in vitro. METHODS:For this purpose, in vitro dexamethasone inhibition of lipopolysaccharide (LPS)-induced interleukin-6 (IL-6) secretion in cultures of peripheral monocytes was compared in 6 untrained...

journal_title：Clinical endocrinology

authors： Duclos M,Minkhar M,Sarrieau A,Bonnemaison D,Manier G,Mormede P

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:A relationship between the serotoninergic and the opiatergic system in the pathogenesis of head pain is supported by several data. This study was carried out to investigate the neuroendocrine effects of sumatriptan, a specific serotonin agonist used in the treatment of migraine, on hypothalamic-pituitary-adre...

journal_title：Clinical endocrinology

authors： Facchinetti F,Nappi RE,Sances G,Fioroni L,Nappi G,Genazzani AR

更新日期：1994-02-01 00:00:00

abstract：:Sixteen consecutive cases of Cushing's disease were treated by radical transphenoidal hypophysectomy. Surgical removal was not possible in two cases. Of the other 14, there was total clinical and biochemical remission of the disease in 13 and partial remission in one. Some form of replacement therapy has been necessar...

journal_title：Clinical endocrinology

authors： Thomas JP,Richards SH

更新日期：1983-11-01 00:00:00

abstract：CONTEXT:Vitamin D-dependent rickets type 1A (VDDR-IA, OMIM 264700) is a rare autosomal recessive disorder and is caused by mutations in the CYP27B1 gene. OBJECTIVES:We aim to investigate CYP27B1 mutation in seven patients from four separate families and characterize the genotype-phenotype correlation. METHODS:The ent...

journal_title：Clinical endocrinology

authors： Durmaz E,Zou M,Al-Rijjal RA,Bircan I,Akçurin S,Meyer B,Shi Y

更新日期：2012-09-01 00:00:00

abstract：:The response of serum calcium, PTH, CT and gastrin to an infusion of secretin (3 CU/kg/h) over a period of 90 min was studied in ten healthy males and two female patients with hypoparathyroidism. In the healthy males serum calcium, after a transient fall, significantly increased at 45 min after the onset of the infusi...

journal_title：Clinical endocrinology

authors： Lo Cascio V,Piubello W,Cominacini L,Vantini I,Galvanini G,Ederle A,Cavallini G,Scuro LA

更新日期：1982-04-01 00:00:00

abstract：:An LHRH test was performed on twenty-eight regularly menstruating females during follicular phase of their cycles. Twenty-four were then given an intramuscular injection of progesterone in oil and retested with LHRH 20 or 44 h later, the remaining four received no pretreatment and acted as controls. The twelve subject...

journal_title：Clinical endocrinology

authors： Shaw RW,Butt WR,London DR

更新日期：1975-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to develop an assay for the measurement of thyroid blocking antibodies (TBAb), based on the ability of patient serum to inhibit TSH stimulated 3H-cAMP production following incubation of FRTL-5 or JPO9 cells with 3H-adenine. The assay was then used to evaluate a child born with neonat...

journal_title：Clinical endocrinology

authors： Michelangeli VP,Poon CW,Arnus EE,Frauman AG,Connelly J,Colman PG

更新日期：1995-01-01 00:00:00

abstract：:In a prospective study of the incidence of thyrotoxicosis sera from 216 thyrotoxic patients in seven English towns were assayed for TSH-receptor antibodies. The incidence of antibody negative thyrotoxicosis correlated closely with the previous prevalence of endemic goitre in the towns (r = 0.9) indicating a high curre...

journal_title：Clinical endocrinology

authors： Phillips DI,Barker DJ,Rees Smith B,Didcote S,Morgan D

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:We recently identified a novel anorexigenic protein, nesfatin-1, which is processed from nesfatin/nucleobindin-2 (NUCB2). However, the clinical importance of this protein has not been determined. OBJECTIVE:To investigate its clinical significance in humans, we have established a new specific enzyme-linked i...

journal_title：Clinical endocrinology

authors： Tsuchiya T,Shimizu H,Yamada M,Osaki A,Oh-I S,Ariyama Y,Takahashi H,Okada S,Hashimoto K,Satoh T,Kojima M,Mori M

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:The Asp727Glu polymorphism in the TSH receptor (TSHR) gene is associated with serum TSH levels. However, the proportion of genetic variation accounted for by this polymorphism is unknown. In this study, we (1) examined the association of the Asp727Glu polymorphism with thyroid size, serum levels of TSH, thyr...

journal_title：Clinical endocrinology

authors： Hansen PS,van der Deure WM,Peeters RP,Iachine I,Fenger M,Sørensen TI,Kyvik KO,Visser TJ,Hegedüs L

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:No single histological or molecular marker is diagnostic for malignant phaeochromocytomas and paragangliomas (PPGLs). This study aimed to establish and evaluate a prognostic nomogram to improve the prediction of metastatic probability in individual PPGL patients. METHODS:Three hundred and 47 consecutive PPGL...

journal_title：Clinical endocrinology

authors： Zhong X,Ye L,Su T,Xie J,Zhou W,Jiang Y,Jiang L,Ning G,Wang W

更新日期：2017-08-01 00:00:00

abstract：:The present study concerns eighteen chronic alcoholics with minimal liver damage. A significant reduction in total serum T4 with an accompanying drop in circulating TBG was observed in these otherwise euthyroid patients. During alcohol withdrawal, we observed a rapid increase in T4 and TBG into the normal range. We su...

journal_title：Clinical endocrinology

authors： Geurts J,Demeester-Mirkine N,Glinoer D,Prigogine T,Fernandez-Deville M,Corvilain J

更新日期：1981-02-01 00:00:00

abstract：:Growth hormone (GH) is widely prescribed for children with short stature across a range of growth disorders. Recombinant human (rh) insulin-like growth factor-1 (rhIGF-1) therapy is approved for severe primary IGF-I deficiency - a state of severe GH resistance. Evidence is increasing for an unacceptably high rate of p...

journal_title：Clinical endocrinology

authors： Bang P,Ahmed SF,Argente J,Backeljauw P,Bettendorf M,Bona G,Coutant R,Rosenfeld RG,Walenkamp MJ,Savage MO

更新日期：2012-08-01 00:00:00