Abstract：
:It is known that kittens reared in ways that restrict movement while visual stimulation is received exhibit deficits in visually guided behavior. Presumably, the behavioral dysfunction is due to a lack of sensorimotor coordination during visual exposure. The current investigation was undertaken to study this effect both physiologically and behaviorally. Two groups of kittens were normally reared until they were nearly 4 weeks old. They were then placed in a darkroom and exposed daily for 1--2 hours while one eye was occluded. On alternate days, alternate eyes were covered. One group was restrained in a body cast while a given eye was exposed, but the kittens were free to move about while the other eye received visual experience. A second control group was alternately occluded, but freely mobile during all exposures. An additional cat was also unrestrained during daily rearing periods and neither eye was ever occluded. Behavioral tests showed clear deficits when the "passive" eye of the restrained-unrestrained group was used. Deficiencies were found in visually guided paw placing, pursuit eye movements, and jumping behavior to a platform. Responses of single cells were studied in area 17 of the visual cortex. Ocular dominance distributions showed marked reductions in binocularity for alternated occluder cats. The eye that had received exposure while animals were active in the restrained-unrestrained group also tended to predominate but the difference was not statistically significant.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Freeman RDdoi
10.1007/BF00238794subject
Has Abstractpub_date
1978-09-15 00:00:00pages
51-63issue
1eissn
0014-4819issn
1432-1106journal_volume
33pub_type
杂志文章abstract：:This study investigates coordination between hand transport and grasp movement components by examining a hypothesis that the hand location, relative to the object, in which aperture closure is initiated remains relatively constant under a wide range of transport speed. Subjects made reach-to-grasp movements to a dowel...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0423-9
更新日期：2006-09-01 00:00:00
abstract：:The purpose of this study was to investigate the temporal relationship between presaccadic neuronal discharges in the frontal eye fields (FEF) and supplementary eye fields (SEF) and the initiation of saccadic eye movements in macaque. We utilized an analytical technique that could reliably identify periods of neuronal...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00241967
更新日期：1995-01-01 00:00:00
abstract：:The developmental pattern of hippocampal mossy fiber (dentate granule cell axon) innervation to the pyramidal cell layer was examined with anterograde transport methods. Injection of 3H-leucine into the dentate gyrus on PN 1 resulted in labeling of the incipient stratum lucidum extending to, but not beyond, the CA3 re...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00248368
更新日期：1988-01-01 00:00:00
abstract：:Previous research has shown that Parkinson's-disease (PD) patients produce irregular movement paths during a rapid arm pointing task. The aim of this study was to investigate the movement paths of PD patients during a prehensile action to objects requiring different levels of precision. Thus, we sought to determine if...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000468
更新日期：2000-10-01 00:00:00
abstract：:The effects of intravenous doses (200 mug) of LSD on the activity of single neurones in the primary visual cortex have been studied in cats anaesthetized with urethane. Cells were stimulated with a bright bar of light moved over the receptive field, and orientation tuning was assessed quantitatively before and after a...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00234826
更新日期：1977-01-18 00:00:00
abstract：:Is it possible to learn to perform a motor sequence without awareness of the sequence? In two experiments, we presented participants with the most elementary sequence: an alternation between two options. We used a double-step pointing task in which the final position of the target alternated between two quite similar ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4566-z
更新日期：2016-06-01 00:00:00
abstract：:The mechanisms by which the nervous system coordinates multiple muscles for the control of finger movements are not well understood. One possibility is that groups of muscles may be enlisted into synergies by last-order inputs that project across multiple motor nuclei. In this study we investigated the role that tacti...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0643-z
更新日期：2006-10-01 00:00:00
abstract：:A strong assumption shared by major theoretical approaches to cognition posits that the human cognitive system has a limited capacity for information processing. Evidence supporting this claim comes from the dual-task paradigm in which one cognitive system has to process two tasks simultaneously. In this study, we exa...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2703-2
更新日期：2011-06-01 00:00:00
abstract：:We investigated the effect of foot position and foot orientation on asymmetrical body weight loading and the inter- and intra-foot coordination dynamics of standing postures. The participants were instructed to stand with the feet side-by-side and in staggered and tandem positions with the right foot oriented at diffe...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3627-9
更新日期：2013-09-01 00:00:00
abstract：:Volume conduction measurements were carried out the brachial biceps, tibialis anterior and deltoid, in normal human subjects. Attenuation constant K and time constant tau of the muscle tissue transfer function were measured, and the average electrode uptake area calculated for the three muscles. The average number of ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238380
更新日期：1981-01-01 00:00:00
abstract：:Chronic loss of vestibular function modifies the role of neck afferents in human perception of self-motion. We characterized this change by comparing the self-motion perception of patients with chronic vestibular loss (Ps) to that of normal subjects (Ns). Stimuli consisted of sinusoidal horizontal rotations (0.025-0.4...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227147
更新日期：1993-01-01 00:00:00
abstract：:Double-labeling combined with elution-restaining immunofluorescence techniques were used to analyze the extent of coexistence among the peptides cholecystokinin (CCK), peptide histidine-isoleucine (PHI)/vasoactive intestinal polypeptide (VIP), substance P and the catecholamine-synthesizing enzyme tyrosine hydroxylase ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00250598
更新日期：1988-01-01 00:00:00
abstract：:Cells in cat's area 17 respond optimally if elongated contrasts are presented at a certain angle or orientation with respect to the retina, or to the visual field, respectively (Hubel and Wiesel, 1962). The preferred orientation and the range of orientation sensitivity of cells in close proximity to one another have b...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00234062
更新日期：1975-12-22 00:00:00
abstract：:EMG responses, vertical and A-P shear forces and kinematics of "automatic postural responses" to unexpected translational perturbations in the headward and tailward directions were studied in cats. Muscles acting on the major joints of the forelimbs and hindlimbs were studied. Movement of the animals in response to pe...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238231
更新日期：1983-01-01 00:00:00
abstract：:When the head rotates, vestibulocollic reflexes counteract the rotation by causing contraction of the neck muscles that pull against the imposed motion. With voluntary head rotations, these same muscles contract and assist the movement of the head. The purpose of this study was to determine if an infinite variety of m...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF02259112
更新日期：1992-01-01 00:00:00
abstract：:It is an unresolved question whether the posture of single fingers relative to each other is represented in the brain within an external frame of reference. In two experiments, we investigated postural influences on the processing of tactile stimuli at fingers and hands. Healthy subjects received two simultaneous tact...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2396-y
更新日期：2010-09-01 00:00:00
abstract：:Earlier studies have shown that eye positions, recorded in subjects scanning a distant visual scene with the head in a stable position, have only two degrees of freedom (Listing's law). Due to cyclovergence, this law is modified in near-vision. Two previous quantitative studies have documented that the sign of the tor...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228754
更新日期：1994-01-01 00:00:00
abstract：:We explored whether the synergic control of the hand during multi-finger force production tasks depends on the hand muscles involved. Healthy subjects performed accurate force production tasks and targeted force pulses while pressing against loops positioned at the level of fingertips, middle phalanges, and proximal p...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-018-5231-5
更新日期：2018-05-01 00:00:00
abstract：:This study addressed some of the controversial issues surrounding the anticonvulsant effect of phenytoin, and the predictive validity of the guinea-pig kindling model for the screening of anticonvulsant drugs. Following an intraperitoneal injection of either 50 or 75 mg/kg phenytoin, we analysed plasma concentrations ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210100852
更新日期：2001-10-01 00:00:00
abstract：:Given the number of muscles and joints of the arm, more ways are available to produce an identical hand movement when pointing to a target than are strictly necessary. How the nervous system manages these abundant degrees of freedom was the focus of this study of pointing to targets of low and high indices of difficul...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1357-5
更新日期：2003-04-01 00:00:00
abstract：:Heparin affin regulatory peptide (HARP), also known as pleiotrophin or heparin-binding growth-associated molecule, is a developmentally regulated extracellular matrix protein that induces cell proliferation and promotes neurite outgrowth in vitro as well as pre- and postsynaptic developmental differentiation in vivo. ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000536
更新日期：2000-12-01 00:00:00
abstract：:Using combined psychophysics and event-related potentials (ERPs), we investigated the effect of perceptual learning on face gender discrimination and probe the neural correlates of the learning effect. Human subjects were trained to perform a gender discrimination task with male or female faces. Before and after train...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3396-x
更新日期：2013-04-01 00:00:00
abstract：:The topographical mapping of glial fibrillary acidic protein (GFAP)-immunoreactivity was performed in coronal serial sections of the rat mesencephalon, rhombencephalon and spinal cord. Relative to a background of poor or moderate overall staining of the mesencephalon, the interpeduncular nucleus, substantia nigra and ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230695
更新日期：1989-01-01 00:00:00
abstract：:Extracellular focal synaptic potentials (FSPs) were recorded in forelimb segments of cats in the region where corticospinal volleys (pyramidal stimulation) gave a maximal FSP. No FSP was recorded in this region on stimulation of the medial part of the lateral reticular nucleus (LRN), provided that ventral spinal pathw...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235897
更新日期：1982-01-01 00:00:00
abstract：:Geniculate cell responses to moving bars and moving texture were compared in normal cats and in cats in which the corticofugal feedback was removed by cortical ablation. In experimental animals the response strength and the velocity upper cutoff assessed with a moving bar was reduced compared to control animals. The s...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00608257
更新日期：1990-01-01 00:00:00
abstract：:Discharges of muscle spindle afferents from the soleus muscle were studied in kittens aged 1-21 days and in adult cats. Vibration applied longitudinally to the tendon elicited one impulse for each cycle of vibration over the range 1-200 Hz for the kittens and up to 450 Hz for the adult. Threshold amplitudes were gener...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00406620
更新日期：1988-01-01 00:00:00
abstract：:The memory for the final position of a moving object which suddenly disappears has been found to be displaced forward, in the direction of motion, and downwards, in the direction of gravity. These phenomena were coined, respectively, Representational Momentum and Representational Gravity. Although both these and simil...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4654-0
更新日期：2016-09-01 00:00:00
abstract：:Abstract. Although the contribution of binocular vision to reach-to-grasp movements has been extensively studied, it has been largely ignored in locomotion. The aim of these studies was to explore the role of binocular vision during the approach phase and step over the obstacle and the contribution of head movements t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0948-x
更新日期：2002-02-01 00:00:00
abstract：:As a functional measure of NMDA receptor effectiveness in kitten striate cortex, the uptake of 45Ca by visual cortical slices was measured after 2 minute bath applications of N-methyl-D-aspartate (NMDA). Significant Ca uptake occurred in response to 12.5-100 microM NMDA in slices prepared from visual cortex of normal ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228153
更新日期：1990-01-01 00:00:00
abstract：:The present study examined the dopaminergic innervation of the rat globus pallidus by in vivo microdialysis and immunohistochemistry in more detail. Using tyrosine hydroxylase immunohistochemistry, two classes of dopaminergic fibers were distinguished morphologically in the globus pallidus. Unilateral infusion of 6-hy...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1638-7
更新日期：2004-01-01 00:00:00
