In vivo aromatization of [3H]testosterone in high and low mating lines of Japanese quail.

Abstract:

:Japanese quail selected bidirectionally for adult mating frequency were utilized to study in vivo aromatization of testosterone (T) in relation to masculine copulatory behavior. Functionally castrated high (HM) and low mating (LM) line quail were injected with 75 microCi of [3H]T. One hour after the injection, all radioactivity recovered in telencephalic-diencephalic brain tissue was in the form of T, dihydrotestosterone (DHT), or estradiol (E2). Neither the total 3H nor the [3H]T metabolite radioactivity differed between the two genetic lines. Of all [3H]T metabolic radioactivity, [3H]E2 represented 45 +/- 6 % in the HM line and 46 +/- 6% in the LM line, indicating that the line difference in mating frequency was not due to a corresponding difference in aromatase activity. Inasmuch as both the HM and LM line birds actively converted T to E2, these results implicate a neural mechanism involving E2-receptor interactions as the cause of the behavioral differences between the HM and LM lines.

journal_name

Horm Behav

journal_title

Hormones and behavior

authors

Cohen-Parsons M,Van Krey HP,Siegel PB

doi

10.1016/0018-506x(83)90031-4

subject

Has Abstract

pub_date

1983-09-01 00:00:00

pages

316-23

issue

3

eissn

0018-506X

issn

1095-6867

pii

0018-506X(83)90031-4

journal_volume

17

pub_type

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