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The organization of astrocytes in organotypic mouse spinal cord culture: an electron microscope study.

Abstract：

:The organization of astrocytes in myelinated culture of mouse spinal cord tissue was analysed ultrastructurally and compared with the pattern in vivo. Astrocyte cell bodies and their processes, connected by punctate adhesions and gap junctions, formed a continuous layer around the entire explant. Throughout the parenchyma, thin astrocytic processes penetrated the neuropil, separated neurons, and invested some synaptic complexes. Others formed flattened sheets and contacted directly with the basal surface of ependymal cells. In the absence of mesenchymal elements, astrocytes in vitro occasionally possessed fragments of basal lamina on the surface of the explant and around minute intercellular spaces. Except for an incomplete basal lamina, these findings indicate that astrocytes in vitro are organized in a manner essentially identical to the situation in vivo.

journal_name

Neuropathol Appl Neurobiol

journal_title

Neuropathology and applied neurobiology

authors

Kusaka H,Hirano A,Bornstein MB,Raine CS

doi

10.1111/j.1365-2990.1984.tb00390.x

subject

Has Abstract

pub_date

1984-11-01 00:00:00

pages

411-22

issue

6

eissn

0305-1846

issn

1365-2990

journal_volume

10

pub_type

杂志文章

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