A technique for the preparation of Tc-99m red blood cells for evaluation of gastrointestinal hemorrhage.

Abstract:

:Tc-99m labeled red blood cell (RBC) preparations are gaining wide acceptance in the diagnosis and localization of gastrointestinal bleeding. A major requirement of the radiopharmaceutical is that the percentage of Tc-99m attached to red cells in the injected dose must be extremely high, since free pertechnetate is secreted into the gastrointestinal tract and may obscure a bleeding site. We have developed a combined in vivo/in vitro labeling procedure which is simple and rapid, and which enables the administration of substantial amounts of RBC-bound Tc-99m and minimizes the amount of unbound technetium present. The technique is readily utilizable in any nuclear medicine clinic and requires no investigative pharmaceuticals.

journal_name

Clin Nucl Med

authors

Benedetto AR,Nusynowitz ML

doi

10.1097/00003072-198304000-00004

subject

Has Abstract

pub_date

1983-04-01 00:00:00

pages

160-2

issue

4

eissn

0363-9762

issn

1536-0229

journal_volume

8

pub_type

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