Abstract:
PURPOSE:To establish camera-based methods for estimating Tc-99m mercaptoacetyltriglycine (MAG3) clearance without blood sampling. MATERIALS AND METHODS:The results of renal scintigraphy with Tc-99m MAG3 obtained from 160 patients were analyzed retrospectively. Eight renogram parameters were calculated for each patient based on the area under the renogram (area method) and slope of the renogram (slope method) using different periods for analysis (1-2 and 1-2.5 minutes for the area method; 0.5-1.5 and 0.5-2 minutes for the slope method) and different backgrounds for subtraction (perirenal and subrenal backgrounds). The 8 parameters were then correlated with MAG3 clearance measured by the single-sample methods proposed by Russell et al and Bubeck et al to determine the equation for the conversion of renogram parameters to clearance. RESULTS:All 8 renogram parameters were highly correlated with clearance measured by the single-sample methods, and the obtained equations enabled the estimation of clearance from image data. Selection between the area and slope methods, between different periods for analysis, or between perirenal and subrenal backgrounds did not cause large differences in the estimation. CONCLUSION:The camera-based methods determined in the present study allow the estimation of MAG3 clearance with acceptable accuracy.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Inoue Y,Ohtomo Kdoi
10.1097/RLU.0b013e31821a2a96subject
Has Abstractpub_date
2011-11-01 00:00:00pages
1012-6issue
11eissn
0363-9762issn
1536-0229pii
00003072-201111000-00009journal_volume
36pub_type
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198906000-00005
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journal_title:Clinical nuclear medicine
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journal_title:Clinical nuclear medicine
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journal_title:Clinical nuclear medicine
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章,评审
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更新日期:2013-07-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
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journal_title:Clinical nuclear medicine
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更新日期:1997-07-01 00:00:00
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journal_title:Clinical nuclear medicine
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doi:10.1097/RLU.0000000000002479
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journal_title:Clinical nuclear medicine
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doi:10.1097/RLU.0000000000001847
更新日期:2017-12-01 00:00:00
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journal_title:Clinical nuclear medicine
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更新日期:1999-10-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001821
更新日期:2017-11-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
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journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
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journal_title:Clinical nuclear medicine
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doi:10.1097/00003072-198802000-00001
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journal_title:Clinical nuclear medicine
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doi:10.1097/RLU.0000000000001021
更新日期:2016-03-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
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更新日期:2013-03-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198506000-00004
更新日期:1985-06-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199810000-00004
更新日期:1998-10-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199008000-00020
更新日期:1990-08-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318219ae3f
更新日期:2011-08-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200008000-00002
更新日期:2000-08-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199705000-00006
更新日期:1997-05-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1097/RLU.0b013e3181e9fa5f
更新日期:2010-09-01 00:00:00