Abstract:
:In two out of three cases of idiopathic fibrosis of the mediastinum there was also retroperitoneal fibrosis, and in one of them extensive fibrosis of the lungs. One of these, a fit middle-aged man, died suddenly with severe coronary artery stenosis due to fibrosis. The third case was that of a young man with a solitary fibrous mass around the right lower lobe bronchus mimicking a malignant tumour and producing bronchial stenosis. Of the various hypotheses about the aetiology and pathogenesis of the fibrous proliferation, that of an autoimmune process seemed the most likely in these cases.
journal_name
J Clin Patholjournal_title
Journal of clinical pathologyauthors
Light AMdoi
10.1136/jcp.31.1.78subject
Has Abstractpub_date
1978-01-01 00:00:00pages
78-88issue
1eissn
0021-9746issn
1472-4146journal_volume
31pub_type
杂志文章abstract::Of the first 250 heart and 35 heart and lung transplant recipients at Papworth Hospital, Cambridge, who survived for more than one month after transplantation, 217 heart and 33 heart and lung patients were investigated serologically for evidence of Toxoplasma gondii infection. Six patients acquired primary T gondii in...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.42.2.194
更新日期:1989-02-01 00:00:00
abstract:AIMS:The aim of this study was to evaluate the mismatch repair gene expression and their correlation with NF-kB in patients with oral squamous cell carcinoma (SCC). METHODS:Total RNA was isolated from 28 biopsy samples. A control group was composed of 20 volunteers. Differential expression of hMSH2, hMSH6 and NF-kB ge...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jclinpath-2019-206161
更新日期:2020-05-01 00:00:00
abstract::Serum C reactive protein concentrations measured by a laboratory based assay were compared with the semiquantitative results obtained with a visual agglutination method (Well-cotest, CRP kit). Using this agglutination kit, diluting serum 1/10 and 1/20 gave C reactive protein results which could be of more clinical val...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.38.4.464
更新日期:1985-04-01 00:00:00
abstract::Four cases of human infection with Achromobacter anitratus, one of which was fatal, are described. They all occurred at one hospital within a period of two months. The bacteriology, antibiotic sensitivity, and pathogenicity of the organisms are discussed. One of the strains was found to differ from the other three. ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.14.6.670
更新日期:1961-11-01 00:00:00
abstract::It was shown that, on average, the titres of the sera obtained by both the anti-complement immunofluorescence (ACIF) and indirect immunofluorescence for viral late antigens (IFA-LA) procedures were approximately eight times higher than those obtained by complement fixation. There was no significant difference between ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.31.9.827
更新日期:1978-09-01 00:00:00
abstract::The material from a case of Tietze's disease has been examined histologically. A review of the literature on the pathology of this lesion correlated with the findings from this case indicates that there is a pathological lesion in the costal cartilage in this disease. This consists of an increased vascularity and dege...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.27.12.960
更新日期:1974-12-01 00:00:00
abstract:AIMS:To evaluate the efficacy of biochemical parameters in different fluids in the diagnosis of myocardial infarction of different causes, analysed after death. METHODS:The myoglobin concentration and total creatine kinase (CK) and creatine kinase MB isoenzyme (CK-MB) activities were measured in serum, pericardial flu...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.48.2.124
更新日期:1995-02-01 00:00:00
abstract::A case of bilateral gonadoblastoma/dysgerminoma in a 46 XY phenotypical female is presented. Increased circulating beta human chorionic gonadotropin (beta-HCG) and testosterone together with a decreased concentration of follicle stimulating hormone (FSH) reflected the activities of these tumours. The patient is alive ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.35.4.420
更新日期:1982-04-01 00:00:00
abstract::Candida spp are the fourth most common group of nosocomial pathogens isolated from patients on medical, surgical, and intensive care wards. Polymicrobial candidaemia has rarely been described. The diagnosis of candidaemia from peripheral blood smears has not been widely reported. This report describes the case of a yo...
journal_title:Journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1136/jcp.2003.9340
更新日期:2004-02-01 00:00:00
abstract::A patient is described in whom a campylobacter enteritis closely resembled ulcerative colitis on clinical, sigmoidoscopic, and histological grounds. Selective stool culture techniques may be necessary to differentiate campylobacter colitis from ulcerative colitis proper. ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.32.10.986
更新日期:1979-10-01 00:00:00
abstract::Current techniques for lymphocyte transformation are evaluated and criticised. A simple technique, designed to meet these criticisms, is described in detail, with particular reference to lymphocyte separation and scoring methods. ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.21.2.175
更新日期:1968-03-01 00:00:00
abstract::Surface immunoglobulins (Ig) of normal and malignant lymphoid cells were detected on prefixed, smeared (method A) and live (method B) cell suspensions; the results were compared with regard to staining patterns, specificity and sensitivity. In both methods surface Ig were detected by a direct immunoperoxidase procedur...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.35.2.139
更新日期:1982-02-01 00:00:00
abstract::This paper describes the modification of a commercially available rapid slide screening test(1) for anti-streptolysin O to give quantitative results. The modified technique is compared with the long-established haemolytic technique of Rantz and Randall (1945). The quantitative results for both techniques are shown to ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.25.6.543
更新日期:1972-06-01 00:00:00
abstract::In cases of adult T cell leukaemia neoplastic T cell infiltration in the skin was accompanied by an increase in Langerhans cells. This is in keeping with the view that Langerhans cells may induce antigen-specific and allogenic T cell activation. ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.36.3.307
更新日期:1983-03-01 00:00:00
abstract::This report describes two cases of Osler's triad of pneumonia, meningitis, and endocarditis, as a result of Streptococcus pneumoniae infection, also called Austrian's syndrome. In the first patient, a 51 year old non-alcoholic man, the aortic valve was affected and needed to be replaced in an emergency operation. The ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1136/jcp.56.11.879
更新日期:2003-11-01 00:00:00
abstract:AIMS:To determine the possible histogenesis of the intracranial variant of olfactory neuroblastoma. METHODS:Four specimens from three cases of intracranial olfactory neuroblastoma were studied by light microscopy and immuno-histochemistry, and electron microscopy in two cases. RESULTS:Light microscopical examination ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.45.4.299
更新日期:1992-04-01 00:00:00
abstract:BACKGROUND:Kaposi's sarcoma is considered to be an angioproliferative disease associated with a novel herpesvirus (KSHV/HHV8), but the precise pathophysiology of the lesion remains unclear. The study of clonality in Kaposi's sarcoma using X linked DNA polymorphism has been difficult so far, because of a very strong pre...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.50.8.664
更新日期:1997-08-01 00:00:00
abstract:AIMS:To describe the prostatic adenectomy specimens of six patients with symptomatic benign prostatic hyperplasia (BPH) who failed to respond to long term treatment with a 5-alpha-reductase inhibitor, finasteride. METHODS:Histological sections from six cases of BPH who had been treated with finasteride were investigat...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.49.4.324
更新日期:1996-04-01 00:00:00
abstract::Two groups of women with non-specific genital infection were treated for two weeks with tetracycline 250 mg six-hourly and minocycline 100 mg twice daily respectively. Cultures for yeasts were performed before treatment and at the end of the first and second weeks. Before treatment yeasts, mostly Candida albicans, wer...
journal_title:Journal of clinical pathology
pub_type: 临床试验,杂志文章
doi:10.1136/jcp.28.5.403
更新日期:1975-05-01 00:00:00
abstract::In two cases of infected total hip replacements, Peptococcus magnus was isolated in pure culture from the implant when it was removed. Fluorescent antibody and ELISA studies have shown that both patients developed an antibody response to this anaerobic coccus soon after the replacement operation. These results suggest...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.32.1.61
更新日期:1979-01-01 00:00:00
abstract::Angiogenesis plays a crucial role in melanoma metastasis and progression. In recent years, numerous studies have investigated the prognostic and clinical significance of this phenomenon, and the development of molecular techniques has enabled us to achieve a better understanding of angiogenesis in melanoma. Herein, we...
journal_title:Journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1136/jclinpath-2015-203482
更新日期:2016-06-01 00:00:00
abstract::In order to classify the underlying disorder in four patients with biopsy-proven amyloidosis without overt monoclonal gammopathy, the cytoplasmic immunoglobulin (Ig) distribution of bone marrow plasma cells was evaluated using direct immunofluorescence microscopy. This procedure revealed the presence of a monoclonal p...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.35.3.285
更新日期:1982-03-01 00:00:00
abstract::Two cancer-associated proteins, carcinoembryonic antigen (CEA) and pregnancy-associated alpha2 glycoprotein (PAG), together with 13 normal serum proteins were measured in the serum and effusion fluid of patients with ascites and pleural effusions. The results indicate that CEA measurement in effusion fluid is more eff...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.30.6.537
更新日期:1977-06-01 00:00:00
abstract:INTRODUCTION/METHODS:After the recognition of contaminating algae on histopathological sections stained by periodic acid Schiff (PAS) and Grocott methods, a detailed audit was undertaken to assess the extent of contamination and its possible source. RESULTS:The contaminating organism was a member of the staurastrum ge...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.2005.026187
更新日期:2005-10-01 00:00:00
abstract::The effect of temperature, time of storage, and presence of air bubbles in specimens for blood gas analysis was studied. The results show that air bubbles in a 10% proportion are undesirable because of significant elevation in the PO2, and the storage of anaerobic blood samples at room temperature (25 degrees C) is ac...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.33.9.864
更新日期:1980-09-01 00:00:00
abstract:AIMS:To investigate a potential diagnostic use of alpha fetoprotein (alpha FP) isoform analysis by lectin affinity electrophoresis to distinguish between endodermal sinus tumours arising in the vagina in infants from those at other sites. METHODS:alpha FP in the serum of a patient with a vaginal endodermal sinus tumou...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.50.10.856
更新日期:1997-10-01 00:00:00
abstract::Forty six lymph nodes were examined with the indirect immunoperoxidase technique for the distribution of fibronectin and laminin. Fibronectin was present in the framework of the tissue and the basal lamina of blood vessels, giving a clear outline of nodal architecture. Intracellular fibronectin was observed in cases o...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.38.8.849
更新日期:1985-08-01 00:00:00
abstract::This report describes a patient with a gastric biopsy specimen showing histomorphological and immunohistochemical appearances indistinguishable from those usually present in lymphocytic gastritis, a rare condition of unknown aetiology with a distinctive phenotype. The patient had a history of a biopsy confirmed T cell...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.2004.017350
更新日期:2004-11-01 00:00:00
abstract::A rapidly fatal case of enteritis necroticans in a 24 year old man with diabetes was caused by Clostridium perfringens type C. The role of beta toxin in the disease is discussed. This type has not been previously described as a causative agent in necrotising bowel disease of man outside endemic areas. ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.37.8.942
更新日期:1984-08-01 00:00:00
abstract:OBJECTIVE:Acute B lymphoblastic leukaemia (B-ALL) is the most common type of childhood malignancy worldwide but little is known of its origin. Recently, many studies showed both a high incidence of Epstein-Barr virus (EBV) infection and high levels of CD4+CD25+Foxp3+(Treg cells) in children with B-ALL. In our study, we...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jclinpath-2016-203803
更新日期:2017-02-01 00:00:00