Behavioural effects of PK 8165 that are not mediated by benzodiazepine binding sites.

abstract：:This study investigated the effects of mobile-phone-type radiation on the cerebral activity of seizure-prone animals. When rats transformed into an experimental model of seizure-proneness by acute subconvulsive doses of picrotoxin were exposed to 2 h GSM-modulated 900 MHz radiation at an intensity similar to that emit...

journal_title：Neuroscience letters

authors： López-Martín E,Relova-Quinteiro JL,Gallego-Gómez R,Peleteiro-Fernández M,Jorge-Barreiro FJ,Ares-Pena FJ

更新日期：2006-05-01 00:00:00

abstract：:It is well known that the CaVα2δ auxiliary subunit regulates the density of high voltage-activated Ca2+ channels in the plasma membrane and that alterations in their functional expression might have implications in the pathophysiology of diverse human diseases such as neuropathic pain. However, little is known concern...

journal_title：Neuroscience letters

authors： González-Ramírez R,Martínez-Hernández E,Sandoval A,Gómez-Mora K,Felix R

更新日期：2018-04-23 00:00:00

abstract：:Cyclosporine A (CsA) is the major immunosuppressive drug used for organ and neural transplantation and the therapy of selected autoimmune diseases. We investigated the effect of CsA on the activity of acetylcholinesterase (AChE) in the frontal cortex, hippocampus, septum, and basal ganglia. AChE was determined spectro...

journal_title：Neuroscience letters

authors： Herink J,Krejcová G,Bajgar J,Svoboda Z,Kvĕtina J,Zivnú P,Palicka V

更新日期：2003-03-27 00:00:00

abstract：:The nucleus raphe magnus belongs to the thermoafferent system. Following iontophoretic choleratoxin b injections in its rostral part, a substantial to large number of anterogradely labeled varicose fibres were observed in the medial and lateral preoptic areas, the bed nucleus, the substantia innominata, the ventral pa...

journal_title：Neuroscience letters

authors： Hermann DM,Luppi PH,Peyron C,Hinckel P,Jouvet M

更新日期：1996-10-04 00:00:00

abstract：:The neurotransmitter gamma-aminobuteric acid (GABA) is believed to have a controlling action on spinal locomotor networks. In spasticity, spinal locomotor networks are thought to play a role. A well known drug in the treatment of spasticity is the GABA(B) agonist Baclofen. We report an inhibitory effect of Baclofen on...

journal_title：Neuroscience letters

authors： de Louw AJ,de Vente J,Steinbusch HP,Steinbusch HW,Troost J,Vles JS

更新日期：2002-03-15 00:00:00

abstract：:Although metabolic syndrome (MS) is recognized as a risk factor for ischemic stroke, little is known about genetic variants that confer susceptibility to ischemic stroke among individuals with or without MS. This study was completed to investigate whether the methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorp...

journal_title：Neuroscience letters

authors： Kim OJ,Hong SH,Jeon YJ,Oh SH,Kim HS,Park YS,Kim EJ,Kim NK

更新日期：2013-01-15 00:00:00

abstract：:The role of dopamine (DA) in the rat locus coeruleus (LC) was investigated by determining the levels of 3,4-dihydroxyphenylacetic acid (DOPAC), DA and noradrenaline (NA) in the LC after pharmacological treatments by pargyline, haloperidol, 6-hydroxydopamine (6-OHDA) and desmethylimipramine (DMI). The DA, DOPAC and NA ...

journal_title：Neuroscience letters

authors： Milon H,McRae-Degueurce A

更新日期：1982-06-30 00:00:00

abstract：:Nor-binaltorphimine (nor-BNI) is kappa opioid receptor (KOR) antagonist with the extremely long duration in mice analgesic assay, in vivo. For the evaluation of long-lasting effect of nor-BNI, brain content and serum concentration of nor-BNI were quantified in comparison with those of naloxone (a short-acting non-spec...

journal_title：Neuroscience letters

authors： Kishioka S,Kiguchi N,Kobayashi Y,Yamamoto C,Saika F,Wakida N,Ko MC,Woods JH

更新日期：2013-09-27 00:00:00

abstract：:The kinetics of the association and dissociation of the tritium-labeled selective and potent dopamine transporter inhibitor N-(3-iodoprop-2E-enyl)-2beta-carbo-[3H]methoxy-3beta-(4'-methylphenyl)nortropane ([3H]PE2I) with the transporter of mouse striatal membranes was studied. The analysis revealed that the specific b...

journal_title：Neuroscience letters

authors： Stepanov V,Järv J

更新日期：2006-12-27 00:00:00

abstract：:Disturbed motor control of the fingers, as revealed by the response to unexpected loading of an object held in a precision grip, or to finger perturbation during isometric holding, has been studied in patients with Huntington's disease (HD) and in normal subjects. In normal subjects unexpected loading elicited a refle...

journal_title：Neuroscience letters

authors： Fellows S,Schwarz M,Schaffrath C,Dömges F,Noth J

更新日期：1997-04-25 00:00:00

abstract：:Neural stem cells (NSCs) persist in the mammalian brain throughout life and protect against hypoxia-ischemia injury. NSCs are being increasingly recognized as a novel therapeutic target for various neurological disorders. Previous research indicates that miR-21 attenuates hypoxia-ischemia induced apoptotic death in va...

journal_title：Neuroscience letters

authors： Chen R,Tai Y,Zhang Y,Wang L,Yang Y,Yang N,Ma S,Xue F,Wang J

更新日期：2019-01-18 00:00:00

abstract：:We studied the effects of low-frequency repetitive transcranial magnetic stimulation (rTMS) on seizure susceptibility in rats. rTMS of 1000 pulses at 0.5 Hz led to a prolonged latency for seizure development after an intraperitoneal injection of pentylenetetrazol. The rTMS effectively prevented the development of stat...

journal_title：Neuroscience letters

authors： Akamatsu N,Fueta Y,Endo Y,Matsunaga K,Uozumi T,Tsuji S

更新日期：2001-09-14 00:00:00

abstract：:The main purpose of the present paper was: (1) to study the phase synchronization pattern in the gamma-band while performing the classical Shepard-Metzler task of mental rotation; (2) to investigate the role of musical training; and (3) to study hemispheric differences in the degree of synchronization during mental ro...

journal_title：Neuroscience letters

authors： Bhattacharya J,Petsche H,Feldmann U,Rescher B

更新日期：2001-09-21 00:00:00

abstract：:The synapsin III gene, SYN3, which belongs to the family of synaptic vesicle-associated proteins, has been implicated in the modulation of neurotransmitter release and in synaptogenesis, suggesting a potential role in several neuropsychiatric diseases. The human SYN3 gene is located on chromosome 22q12-13, a candidate...

journal_title：Neuroscience letters

authors： Chen Q,Che R,Wang X,O'Neill FA,Walsh D,Tang W,Shi Y,He L,Kendler KS,Chen X

更新日期：2009-11-20 00:00:00

abstract：:The effects of histamine (HA) on the resting membrane potential and input resistance of rat medial vestibular nucleus (MVN) neurons were investigated using intracellular recording techniques from a submerged brain slice preparation. The exogenous application of HA predominantly produced a concentration-dependent membr...

journal_title：Neuroscience letters

authors： Phelan KD,Nakamura J,Gallagher JP

更新日期：1990-02-16 00:00:00

abstract：:The individual biological activities of many neurotrophic factors and their variants, which are produced by alternative splicing and proteolytic processing, often remain to be characterized. Bacterial protein production combined with protein refolding and purification is a conventional procedure to obtain active neuro...

journal_title：Neuroscience letters

authors： Wang R,Iwakura Y,Araki K,Sotoyama H,Takei N,Nawa H

更新日期：2011-06-22 00:00:00

abstract：:We examined age effects on Movement related potentials (MRPs) in 13 young (mean age = 29.3 years) and 13 old (mean age = 67.2 years) normal adults in right, left and bimanual self-paced button press conditions. Both the groups generated a slowly rising readiness potential (RP) at about 1000 ms, a negative shift (NS') ...

journal_title：Neuroscience letters

authors： Singh J,Knight RT,Woods DL,Beckley DJ,Clayworth C

更新日期：1990-10-30 00:00:00

abstract：:An attempt was made to identify the immunoreactive substance P (SP) released from isolated rat spinal cords using reversed-phase high-performance liquid chromatography (HPLC) combined with radioimmunoassay (RIA) for SP. Soaking the spinal cords of newborn rats in Krebs solution containing 90 mM K+ evoked a release of ...

journal_title：Neuroscience letters

authors： Akagi H,Otsuka M,Yanagisawa M

更新日期：1980-12-01 00:00:00

abstract：:Partial depolarization of primary cerebellar neuronal cultures with K+ evoked the release of aspartate, glutamate, adenosine, serine, taurine, gamma-aminobutyric acid (GABA), alanine and proline. The dihydropyridine calcium channel agonist, BAY K 8644, significantly augmented the K+-induced release of adenosine, aspar...

journal_title：Neuroscience letters

authors： Philibert RA,Dutton GR

更新日期：1989-07-17 00:00:00

abstract：:We studied event-related desynchronization (ERD) of the 8-13 Hz rhythm (mu rhythm) of the primary somatosensory cortex (SI) caused by contra- and ipsilateral median-nerve stimulation. We used whole-head magnetoencephalography (MEG) and wavelet analysis together with our newly developed color-coded single-trial ERD dis...

journal_title：Neuroscience letters

authors： Nikouline VV,Linkenkaer-Hansen K,Wikström H,Kesäniemi M,Antonova EV,Ilmoniemi RJ,Huttunen J

更新日期：2000-11-24 00:00:00

abstract：:Nerve growth factor (NGF) protein has been implicated in alterations of cognitive function either following brain damage, selective lesions or aging. Groups of rats were given long-term (48 weeks) oral barbital treatment or tap water and following an extended period of abstinence (14 weeks) were tested for spatial lea...

journal_title：Neuroscience letters

authors： Wahlström G,Archer T,Lärkfors L

更新日期：1992-03-16 00:00:00

abstract：:The formation of the beta pleated configuration of the amyloid peptide fragment 25-35 in aqueous solution, has been studied using thioflavin-T fluorescence as an indicator of such folding. Both phosphate and adenosine triphosphate (ATP) enhance the formation of aggregated beta-sheets. This phosphate-induced aggregatio...

journal_title：Neuroscience letters

authors： Bondy SC,Truong A

更新日期：1999-05-21 00:00:00

abstract：:Retinal progenitor cells (RPCs) are an excellent resource for retinal replacement therapy, because they show enormous potential to differentiate into retinal-specific cell types. While the differentiating influence of serum has long been appreciated, the effects of serum concentration on RPC differentiation into speci...

journal_title：Neuroscience letters

authors： Hu Y,Ji J,Xia J,Zhao P,Fan X,Wang Z,Zhou X,Luo M,Gu P

更新日期：2013-02-08 00:00:00

abstract：:In the rat, unilateral intrastriatal injection of monoclonal antibodies to acetylcholinesterase (AChE) produced ipsilateral disappearance of AChE-positive nerve terminals within striatum and adjacent cortex. No alterations in striatal staining patterns were observed for tyrosine hydroxylase, somatostatin, neuropeptide...

journal_title：Neuroscience letters

authors： Bean AJ,Xu Z,Chai SY,Brimijoin S,Hökfelt T

更新日期：1991-11-25 00:00:00

abstract：:The distribution of neurons expressing beta-endorphin immunoreactivity was explored in the brain of adult jerboa during two distinct periods characterizing its reproductive cycle. A large presence of cell bodies displaying beta-endorphin immunoreactivity occured within different parts of the mediobasal hypothalamus al...

journal_title：Neuroscience letters

authors： El Ouezzani S,Tramu G,Magoul R

更新日期：2005-03-11 00:00:00

abstract：:The actions of huperzine A (HupA), a novel cholinesterase inhibitor, on the sustained potassium current were investigated in acutely dissociated hippocampal neurons of rat. HupA inhibited the current (IC(50) = 856 +/- 1 microM) with voltage-dependency. The effect was insensitive to 3 microM atropine. Tacrine (IC(50) =...

journal_title：Neuroscience letters

authors： Li Y,Hu GY

更新日期：2002-08-30 00:00:00

abstract：:It is known that articulating different syllables is linked to different grasp actions, e.g. [ti] is linked to precision grip, and [kɑ] to power grip. The aim of the present study was to test whether articulating or hearing these syllables would result in an increased activity in the representation of hand muscles inv...

journal_title：Neuroscience letters

authors： Komeilipoor N,Tiainen M,Tiippana K,Vainio M,Vainio L

更新日期：2016-05-04 00:00:00

abstract：:Cocaethylene is an active cocaine metabolite that targets mammalian neural reward pathways and thus contributes to the reinforcing and addictive properties of ethanol and cocaine. Using gas chromatography-mass spectrometry, we find that fruit flies (Drosophila melanogaster) possess a cellular mechanism through which c...

journal_title：Neuroscience letters

authors： Torres G,Horowitz JM

更新日期：1999-03-26 00:00:00

abstract：:Na+, K+-ATPase is one of major membrane proteins that has two subunits, alpha and beta. The alpha subunit has the ATPase activity and the ouabain binding site. Among four isoforms of the alpha subunit, expression of alpha1, alpha2, and alpha3, but not alpha4, is observed in matured rat brain. Ouabain is one of cardiac...

journal_title：Neuroscience letters

authors： Taguchi K,Kumanogoh H,Nakamura S,Maekawa S

更新日期：2007-02-08 00:00:00

abstract：:In 8 subjects the spontaneous termination of sleep was determined after repetitive exposure to either bright or dim light, between 6.00 and 9.00 h, on 3 days preceding sleep assessment. Sleep duration was significantly shorter following bright light than following dim light. During sleep the time course of EEG energy ...

journal_title：Neuroscience letters

authors： Dijk DJ,Visscher CA,Bloem GM,Beersma DG,Daan S

更新日期：1987-01-14 00:00:00