Abstract:
:In a series of experiments in which the known projections of the septal complex to the hippocampal formation have been transected, we have used both anterograde and retrograde tracing techniques in an attempt to demonstrate a ventral septo-hippocampal pathway. In cases where transections of the fimbria, dorsal fornix and supracallosal stria were complete, injections of the retrograde tracers wheat germ agglutinin-conjugated horseradish peroxidase or Fast blue, resulted in labeled cells in the ipsilateral septal complex, primarily in the nucleus of the diagonal band. The number of cells labeled in these experiments was approximately 5-10% of that seen in experiments in animals with intact dorsal pathways who had received similar injections. The presence of a ventral pathway was confirmed in anterograde labeling experiments in which injections of 3H-amino acids were made into the septal complex. The autoradiographs demonstrated that the projection terminates most heavily in the entorhinal cortex and to a lesser extent in the ventral subicular complex; there may be an additional minor projection to the temporal half of the hippocampus and dentate gyrus. Finally, using double labeling procedures, we were able to demonstrate that at least a portion of the cell population that gives rise to the ventral pathway demonstrates choline acetyltransferase immunoreactivity and is presumably cholinergic.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Milner TA,Amaral DGdoi
10.1007/BF00235290subject
Has Abstractpub_date
1984-01-01 00:00:00pages
579-85issue
3eissn
0014-4819issn
1432-1106journal_volume
55pub_type
杂志文章abstract::In an attempt to identify cholinergic neurons of the brain stem which project to the forebrain, retrograde labeling of neurons in the brain stem was examined by autoradiography following injections of 20 microCi [3H]choline into the thalamus, hypothalamus, basal forebrain and frontal cortex. After injections into the ...
journal_title:Experimental brain research
pub_type: 杂志文章
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journal_title:Experimental brain research
pub_type: 杂志文章
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更新日期:1994-01-01 00:00:00
abstract::Deep brain stimulation of the subthalamic nucleus (STN DBS) significantly improves clinical motor symptoms, as well as intensive aspects of movement like velocity and amplitude in patients with Parkinson's disease (PD). However, the effects of bilateral STN DBS on integrative and coordinative aspects of motor control ...
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journal_title:Experimental brain research
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更新日期:1984-01-01 00:00:00
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abstract::The McGurk effect, which denotes the influence of visual information on audiovisual speech perception, is less frequently observed in individuals with autism spectrum disorder (ASD) compared to those without it; the reason for this remains unclear. Several studies have suggested that facial configuration context might...
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pub_type: 杂志文章
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journal_title:Experimental brain research
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更新日期:2016-11-01 00:00:00
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journal_title:Experimental brain research
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更新日期:1980-01-01 00:00:00
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journal_title:Experimental brain research
pub_type: 杂志文章
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更新日期:2013-04-01 00:00:00
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journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231777
更新日期:1991-01-01 00:00:00
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journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237983
更新日期:1984-01-01 00:00:00
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journal_title:Experimental brain research
pub_type: 杂志文章
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更新日期:1998-09-01 00:00:00
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pub_type: 杂志文章
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journal_title:Experimental brain research
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journal_title:Experimental brain research
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更新日期:2007-09-01 00:00:00
abstract::Under free-viewing conditions, the leftward stimulus features are frequently overestimated (pseudoneglect). This asymmetry could reflect the operation of: (a) spatial attention mechanisms in the right hemisphere (RH) or, (b) stimulus-specific activation. To test these propositions, we attempted to induce a stimulus-sp...
journal_title:Experimental brain research
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更新日期:2006-06-01 00:00:00
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journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050701
更新日期:1999-04-01 00:00:00
abstract::While diverging efficacy and inter-individual response variability have repeatedly been reported for paired-associative stimulation (PAS), approaches to overcome these issues are yet lacking. Hence, the aim of the present study was to determine whether response variability could be reduced through the application of a...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
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更新日期:2019-07-01 00:00:00
abstract::We examined ERP responses during the generation of word associates or mental images in response to concrete and abstract concepts. Of interest were the predictions of dual coding theory (DCT), which proposes that processing lexical concepts depends on functionally independent but interconnected verbal and nonverbal sy...
journal_title:Experimental brain research
pub_type: 杂志文章
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更新日期:2011-07-01 00:00:00
abstract::Pieces of the developing cerebellar anlage were prepared from 13-15 day old rat embryos and transplanted to the cerebellar region of 5-7 and 13-14 day old rat pups. Approximately two months later, sections showed most grafts to consist of both cerebellar cortex, with a typical trilaminar organization, and white matter...
journal_title:Experimental brain research
pub_type: 杂志文章
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更新日期:1984-01-01 00:00:00
abstract::Vigilance is the ability to sustain attention to information for prolonged periods of time, particularly in environments where critical signals may be rare. Recent research in the domain of mind-wandering has suggested that processes associated with mind-wandering may underpin the typical decline in vigilance task per...
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