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Nucleotide sequence at the binding site for coat protein on RNA of bacteriophage R17.

Abstract：

:The binding of a few molecules [1-6] of RNA bacteriophage coat protein to 1 molecule of RNA represses in vitro translation of the RNA synthetase cistron. Digestion of the complex, R17 coat protein-R17 RNA, by T1 RNase yields an RNA fragment bound to the coat protein. The nucleotide sequence of this fragment (59 residues) reveals that it contains the punctuation signal between the coat protein and RNA synthetase cistrons, suggesting that this is the site on the RNA where the coat protein acts as a translational repressor.

journal_name

Proc Natl Acad Sci U S A

journal_title

Proceedings of the National Academy of Sciences of the United States of America

authors

Bernardi A,Spahr PF

doi

10.1073/pnas.69.10.3033

subject

Has Abstract

pub_date

1972-10-01 00:00:00

pages

3033-7

issue

10

eissn

0027-8424

issn

1091-6490

journal_volume

69

pub_type

杂志文章

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