Abstract：
:The aims of regional therapy are to increase the exposure of regional confined cancers to drugs and to decrease their systemic levels. Two main approaches are available: intra-vascular and intra-lymphatic (I.L.) therapy. The former is comprised of different methods of delivering chemo-radio therapeutic agents directly to the tumor, i.e. intra-arterial infusion (I.A.I.), isolation perfusion (I.P.), tourniquet infusion (T.I.), trans-catheter embolization (T.C.E.) and intra-portal infusion (I.P.I.). The main aim of the latter is the prevention or cure of lymphatic metastases. So far none of the reported methods have been universally accepted. Pharmacokinetic studies have recently made I.A.I. a more rational method: the increase in regional exposure achieved is a direct function of the total body clearance of a drug and an inverse function of the regional arterial blood flow. I.A.I. is most effective in the treatment of hepatic metastases from carcinoid and colo-rectal cancer. I.P. gives objective response in 50% of recurrent melanomas. T.I., T.C.E., I.P.I. and I.L. therapy are still experimental methods. However, the future for regional therapy appears exciting, since pharmacological and technological developments seem to have greatly improved its potential effectiveness as a cancer treatment.
journal_name
Int Surgjournal_title
International surgeryauthors
Rossi CR,Nitti D,Favretti F,Lise Msubject
Has Abstractpub_date
1986-01-01 00:00:00pages
42-7issue
1eissn
0020-8868issn
2520-2456journal_volume
71pub_type
杂志文章,评审abstract：:Between 1965 and 1979, 934 patients underwent 1,057 operations for extracranial carotid stenosis at this institute, and over a recent 30-month period 463 patients underwent 511 operations of this type. This number is equal to the total of operations performed during the years 1965-1976. The increase in the frequency o...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1981-07-01 00:00:00
abstract：:En bloc resection of the esophagus was attempted by right thoracotomy, laparotomy, and left cervicotomy in 82 patients suffering from an esophageal cancer. Tumors were classified by the depth of wall penetration and node involvement: 21 tumors penetrated at the most into but not through the muscle (W1), and 61 invaded...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:Expanded polytetrafluoroethylene (Gore Tex) grafts were used for the replacement of the superior or inferior vena cava in dogs. When examined 2 weeks to 18 months after the replacement, the overall patency rate was 82%. If neither deformation nor narrowing of the graft on examination by cavagram had occurred within 14...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1981-07-01 00:00:00
abstract：:The use of imaging techniques and their increasing sensitivity have resulted in increased detection of incidentalomas of the endocrine organs. The aim of our study was to review the currently used evaluation schemes and the outcomes of surgical and conservative management of adrenal incidentalomas at an Indian center....
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
abstract：:A totally implantable system was used for prolonged intravenous treatment in patients whose peripheral veins could no longer be punctured. Our experience showed this device, which was used for short periods in 20 patients, to be an effective solution to the problem of permanent venous access. ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1985-07-01 00:00:00
abstract：:For a better quality of life in rectal cancer patients, high dose radiotherapy following abdominoperineal resection of the rectum with a pelvic partition is another surgical option replacing extended abdominoperineal resection. In addition to pelvic partition with polyglycolic acid mesh, the tissue expander was insert...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:The prognostic value of intra-operative peritoneal lavage cytology and chemotherapy was evaluated retrospectively. METHOD:Lavage cytology was performed in 257 patients. Prognosis was investigated in 85 of pT3 and pT4 patients with radical gastrectomy. Intra-operative chemotherapy was selected according to t...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1999-07-01 00:00:00
abstract：:We retrospectively evaluated rectal cancer surgery cases in which resection had been performed for invasion of other organs in terms of pathologic findings from the viewpoint of sex differences. We enrolled 61 consecutive patients with rectal cancer who had undergone curative surgery with resection of invaded adjacent...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-13-00027.1
更新日期：2013-07-01 00:00:00
abstract：:A retrospective analysis of 88 ovarian tumours diagnosed over five years (1980-1984) in multi-racial Singaporean Oriental women revealed 70 (79%) epithelial tumours (ET), 17 (8%) sex cordstromal (SCS), six (7%) germ cell (GCT) and five (6%) secondary (metastatic) (SEC) cancers. The racial proportions and histological ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:Fecoflowmetry (FFM) has been introduced to simulate natural anorectal evacuation. So far, few reports have described the effect of the herbal medicine Daikenchuto (DKT) on impaired anorectal motor function. The aim of this pilot study was to assess anorectal motor function by FFM in postoperatively impaired patients w...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2010-10-01 00:00:00
abstract：:The diagnosis and management of ovarian hemorrhage complicating anticoagulant therapy is discussed and a case presented. The patient, who had undergone mitral valve replacement and was receiving chronic anticoagulation treatment, was admitted with signs of intraperitoneal bleeding from a ruptured ovarian hematoma. Thi...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1982-10-01 00:00:00
abstract：:Cystosarcoma phyllodes is a rare breast lesion representing between 0.5 and 2.5 percent of all breast tumors. Its microscopic and clinical features are impressive. When first described by J. Mueller in 1838, the lesion was thought to be a benign neoplasm without metastatic potential. Nevertheless, more recent reports ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：:14 cases of silent perforation of the uterus by the Lippes loop are presented. Loop perforations are usually asymptomatic and can be treated conservatively. If complications occur, they require surgical intervention with posterior colpotomy being the procedure of choice if the loop is in the pelvic cavity. Laparoto...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1973-05-01 00:00:00
abstract：:The standard surgical approach to multiple polyposis has been a total proctocolectomy and an end ileostomy because of the premalignant nature of the disease. This operation has been successful, but has resulted in a significant amount of psychological trauma due to the presence of an abdominal stoma. For that reason, ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1985-10-01 00:00:00
abstract：:An 85-year-old woman with no history of abdominal surgery complained of abdominal pain and vomiting and was referred to us with a diagnosis of intestinal obstruction a few days later. Upon admission to our facility, she presented with marked abdominal swelling and prominent kyphosis. Because of the kyphosis, most of t...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-12-00003
更新日期：2013-07-01 00:00:00
abstract：PURPOSE:To present 10 patients who complained of passage of frequent loose stools which was found to be due to sigmoid colon hyperreflexia, a condition that, to our knowledge, has not been described before. PATIENTS AND METHODS:Ten patients (6 women, 4 men, mean age 46.6 years) complaining of frequent loose stools of ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2000-04-01 00:00:00
abstract：:The objective of this study was to assess the diagnostic value of preoperative cytology and galactography in women with nipple discharge using a simple intraductal aspiration method. From May 1997 to February 2002, 172 patients with unilateral, spontaneous nipple discharge without palpable masses underwent intraductal...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2003-04-01 00:00:00
abstract：:In a recent six-year-period, a total of 402 patients underwent parietal cell vagotomy (PCV) for duodenal ulcer. An overall clinical assessment by Visik grading placed 328 (82%) in grade I, 56 (14%) in grade II, 12 (3%) in grade III and 4 (1%) with recurrent ulcer in grade IV. Results of the gastric secretory tests sho...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1981-10-01 00:00:00
abstract：:We investigated the effect of RET c.2307T>G polymorphism on the outcomes of posterior sagittal neurectomy for Hirschsprung disease (PSNHD) procedure in Indonesia. Hirschsprung disease (HSCR) is a neurocristopathy characterized by absence of enteric ganglia along variable lengths of the intestine in neonates. The RET c...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-14-00082.1
更新日期：2014-11-01 00:00:00
abstract：:A case of carcinoid syndrome in a patient receiving treatment for a malignant non-B-cell tumor of the pancreas is presented, and a survival of >14 years is noted. The probable cause is discussed. The literature is reviewed. It was found that such a presentation is rare, and long-term survival in these cases exceedingl...
journal_title：International surgery
pub_type： 杂志文章,评审
doi：
更新日期：2009-01-01 00:00:00
abstract：:For many years, treatment of spontaneous pneumothorax (SP) has been a matter of debate. Since the introduction of videothoracoscopy, videothoracoscopic procedures have replaced thoracotomy as the ultimate procedure for treatment of complicated cases of SP in many institutes. However, the place of (video) thoracoscopy ...
journal_title：International surgery
pub_type： 杂志文章,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：:Fifty-one cases of elbow ankylosis treated with fascial arthroplasty were studied. Forty-two cases (85.4%) of elbow ankylosis were due to injuries; chronic dislocation (24), traumatic myositis ossificans (14) and gunshot wounds (4). Eight were due to infection and one to congenital humero-radial synostosis. Seventy-si...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:Seven cases of symptomatic non-parasitic congenital cysts of the liver are reported. Preoperative correct diagnosis can be established with non-invasive examinations, essentially with echotomography. Laparoscopy can represent a decisive investigation, permitting the direct view of the cysts. Surgical treatment of non-...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1982-10-01 00:00:00
abstract：:We describe the case of a patient with a diaphragmatic hernia associated with radiofrequency ablation for hepatocellular carcinoma who was successfully treated by laparoscopic surgery. A 62-year-old man with a long history of hepatitis C-induced liver cirrhosis was admitted to our institution because of recurrent post...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-14-00025.1
更新日期：2014-07-01 00:00:00
abstract：:The effect on cellular immunity of the administration of the non-specific immunopotentiator BCG and/or a streptococcal agent was studied in 90 non-cancer bearing Wistar rats under different nutritional support. The number of immunocompetent cells and the non-specific function of the immunocompetent cells significantly...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:Primary carcinoma of the male urethra accounts for less than 1% of malignancies in men. Mucinous adenocarcinoma of the urethra is extremely rare, and its biologic behavior is poorly understood. We present herein a rare case of mucinous urethral adenocarcinoma in a male patient with longstanding ulcerative colitis and ...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-13-00073.1
更新日期：2014-09-01 00:00:00
abstract：:Massive lower gastrointestinal hemorrhage originates in the colon in 70% of cases. In half the remaining cases it originates in the small bowel, and in the other half in the duodenum. Currently available diagnostic techniques are: mesenteric angiography, barium contrast meal studies, colonoscopy, and laparotomy. Cause...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1980-03-01 00:00:00
abstract：:Of 144 cases of pancreatoduodenectomy we treated 6 patients (4.2%) with delayed massive bleeding. Massive hemorrhage occurred 14 to 38 days later. Leakage of the pancreatojejunostomy was confirmed in all patients. A "sentinel bleed" was evident in five patients with arterial bleeding. One patient with hemorrhage of th...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：:A 46-year-old man underwent living-donor liver transplantation and splenectomy for primary biliary cirrhosis. On postoperative day 22, cloudiness of ascites increased, and triglyceride concentration in ascites was as high as 1046 mg/dL. With a diagnosis of chylous ascites, total parenteral nutrition was started. Nine ...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/CC118.1
更新日期：2012-10-01 00:00:00
abstract：PURPOSE:To develop a non-obese diabetic rat model for sleeve gastrectomy with modified jejunoileal bypass (SG/MJIB) and to investigate its effectiveness and safety for inducing diabetic control. MATERIALS AND METHODS:Thirty-five 13-week-old male Goto-Kakizaki rats were randomly assigned to the pair-fed to sham-operate...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-15-00162.1
更新日期：2015-07-16 00:00:00
