Abstract:
PURPOSE:To develop a non-obese diabetic rat model for sleeve gastrectomy with modified jejunoileal bypass (SG/MJIB) and to investigate its effectiveness and safety for inducing diabetic control. MATERIALS AND METHODS:Thirty-five 13-week-old male Goto-Kakizaki rats were randomly assigned to the pair-fed to sham-operated SG/MJIB (PFSO-SG/MJIB), SG/MJIB, PFSO-SG, SG, and control groups. The experimental period was 16 weeks post-operatively. Body weight; food intake; glycemic control outcomes; and ghrelin, glucagon-like peptide 1 (GLP-1), glucose-dependent insulinotropic peptide (GIP), and insulin levels were measured. RESULTS:The operated and PFSO groups showed significant weight loss 4 weeks post-operatively compared to the control. The SG/MJIB and SG groups exhibited a significant improvement in oral glucose tolerance and insulin tolerance compared to the PFSO and control groups. The improved effects in the SG/MJIB group were better than those in the SG group. The SG/MJIB and SG groups showed decreased fasting ghrelin levels and increased levels of GLP-1 secretion 2 and 16 weeks post-operatively. Compared to the SG group, only the SG/MJIB group showed higher glucose-stimulated GLP-1 levels and significantly improved insulin secretion. CONCLUSION:SG/MJIB may be an effective, steady hypoglycemic surgical model, showing better diabetic control than SG. The hindgut may play a direct role in ameliorating glucose homeostasis.
journal_name
Int Surgjournal_title
International surgeryauthors
Zhu Z,Yang X,Wang Z,Zhao Y,Yu M,Fan Hdoi
10.9738/INTSURG-D-15-00162.1subject
Has Abstractpub_date
2015-07-16 00:00:00eissn
0020-8868issn
2520-2456pub_type
杂志文章abstract::Salivary gland neoplasms represent the most complex and diverse group of tumors encountered by the head and neck oncologist. Their diagnosis and management is complicated by their relative infrequency. The significance of the study was to analyze the different types of salivary gland tumors, the modalities of treatmen...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract::The aim of the earliest possible diagnosis of breast carcinoma achieved through the integration of clinical, mammographic, sonographic and cytologic data has determined an increased detection of breast lesions and a greater accuracy in their description. Nevertheless, the nature of some of these lesions cannot be well...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract::Fifty-one cases of elbow ankylosis treated with fascial arthroplasty were studied. Forty-two cases (85.4%) of elbow ankylosis were due to injuries; chronic dislocation (24), traumatic myositis ossificans (14) and gunshot wounds (4). Eight were due to infection and one to congenital humero-radial synostosis. Seventy-si...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::We aimed to investigate whether tolerogenic dendritic cells (DCs) were induced in the tolerant recipients with the blockade of CD40-CD40L costimulation. Mouse heterotopic heart transplantation was performed. DCs were sorted from rejected and tolerant recipients using magnetic-activated cell sorting. Their expression o...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2010-04-01 00:00:00
abstract::A proper preoperative staging of rectal tumors is important for correct treatment planning. We included in our study 23 patients with rectal carcinoma in order to evaluate the diagnostic accuracy of endorectal MRI. This technique enabled us to show neoplasms as a hyperintense lesion as compared to the muscolaris. To b...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::Regarding the complications of peptic ulcer, a perforation remains the most important fatal complication. The aim of our retrospective study was to determine relations between postoperative morbidity and comorbid disease or perioperative risk factors in perforated peptic ulcer. In total, 239 patients who underwent eme...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/INTSURG-D-14-00187.1
更新日期:2015-05-01 00:00:00
abstract::Video-assisted thoracoscopic surgery (VATS) has emerged as a minimally invasive therapy of bronchogenic carcinoma, when the diseases occur in patients unable to tolerate open thoracotomy who are 80 years old or older. We report on an 80-year-old man with poor pulmonary function and an 83-year-old man, who were treated...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract::The authors present their experience with 39 cases of pre and postoperative percutaneous transhepatic cholangioscopy (PTCS), listing the indications and advantages of this new tool for the study of the biliary tract and the therapy of several pathological conditions that would otherwise be untreatable. ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1983-10-01 00:00:00
abstract::Radiofrequency ablation of the liver for primary and metastatic disease is used for patients who are not candidates for resection or in conjunction with resection. The technique is simple, and the morbidity rate is low. A case of intrahepatic pseudoaneurysm after radiofrequency ablation of a centrally located hepatoce...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2008-11-01 00:00:00
abstract::A retrospective study of 46 patients who received bupivacaine local injections after hemorrhoidectomy were compared to a matching group of 46 patients of similar age and sex distribution who underwent the same operation. Pain medications requirement on the same day of operation and on subsequent days were measured and...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::A case of acute mesenteric ischemia and massive intestinal infarction secondary to bilateral lumbar sympathectomy and without any other apparent precipitating factors is presented. Its characteristics and findings significantly agree with those described as part of the mesenteric arterial steal syndrome. Although this...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1979-05-01 00:00:00
abstract::The results of a European survey on pneumatic dilatation in the treatment of achalasia have been compiled from a questionnaire completed by 18 different surgical teams. The total number of patients investigated was 2,161. Surgical treatment was prescribed by 94% of teams, whereas pneumatic dilatation was only prescrib...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::To fit for internal fixation of unstable fractures of various parts of the curved pelvis, plates of different shapes and sizes were devised. The plates were used in 18 clinical cases. The late complications such as leg length inequality, pelvic obliquity and low back pain were effectively avoided. ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The authors report their experience of the surgical treatment of varicocele. After having performed modified Palomo's method for many years, recent pathogenetic data have induced them to adopt a microsurgical technique. This technique involves vascular anastomoses which allow drainage of the testicular blood into an a...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1989-10-01 00:00:00
abstract::Expanded polytetrafluoroethylene (Gore Tex) grafts were used for the replacement of the superior or inferior vena cava in dogs. When examined 2 weeks to 18 months after the replacement, the overall patency rate was 82%. If neither deformation nor narrowing of the graft on examination by cavagram had occurred within 14...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1981-07-01 00:00:00
abstract::A 57-year-old woman without any past medical history underwent abdominoperineal resection for rectal cancer in our department. On postoperative day 15, the patient complained of sudden abdominal pain, and high fever was noted in addition to the appearance of erythema around the stoma. The diagnosis of phlegmon was mad...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/INTSURG-D-13-00206.1
更新日期:2015-01-01 00:00:00
abstract::Endometriosis is an ectopic occurrence of tissue morphologically and functionally resembling endometrial tissue in regions outside the uterine cavity. Although scar endometriosis after surgery has been shown to be most common among all the extrapelvic forms of endometriosis, endometriosis after bladder exstrophy surge...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/INTSURG-D-12-00011.1
更新日期:2013-04-01 00:00:00
abstract::A 53-year-old man with multiple liver metastasis of esophageal cancer underwent four courses of chemotherapy. After four courses of chemotherapy, positron emission tomography showed progressive disease. Because it was difficult to control the cancer only by chemotherapy, we performed proton beam therapy (PBT) combined...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/INTSURG-D-13-00188.1
更新日期:2015-01-01 00:00:00
abstract::Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma in late adult life. It occurs most frequently in the extremities (70%), followed by the retroperitoneum (16%). The occurrence of MFH in the spermatic cord is extremely rare (approximately 50 cases in the literature). We are reporting one case ...
journal_title:International surgery
pub_type: 杂志文章,评审
doi:
更新日期:2009-07-01 00:00:00
abstract::Forty-one symptom-free women treated by operative and irradiation therapy for gynecological cancer 24-108 months previously were examined by small bowel barium meal, large bowel barium enema, intravenous urography and renography in order to determine whether there were any silent complications present after the therap...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1981-07-01 00:00:00
abstract::En bloc resection of the esophagus was attempted by right thoracotomy, laparotomy, and left cervicotomy in 82 patients suffering from an esophageal cancer. Tumors were classified by the depth of wall penetration and node involvement: 21 tumors penetrated at the most into but not through the muscle (W1), and 61 invaded...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::Fifteen orthotopic liver transplants were performed from 23 April 1986 to June 1987 in 14 patients (age range 3-56 years). In 12 transplants, extracorporeal bypass was used. The installation was effected by suprahepatic and infrahepatic cava-caval and portaportal anastomoses. Arterial anastomosis was realized after re...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1991-04-01 00:00:00
abstract::Mechanical trauma, thermal injury, tissue ischemia during the operation, postoperative infections, and foreign body reactions are important factors for adhesion formation. Bleeding and bile leakage after liver resections can also cause intra-abdominal adhesions. We aimed to evaluate the intra-abdominal adhesions after...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Pathological and clinical characteristics of thyroid carcinoma are reported. In 379 routine consecutive autopsies in which carcinoma was not suspected, serial sections of thyroid gland were histologically examined. Latent thyroid carcinoma was detected in 15.7% of the glands. Papillary adenocarcinoma comprised 76.3%, ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1976-10-01 00:00:00
abstract::This paper reports a case of ectopic abdominal pregnancy following total hysterectomy and reviews the literature. Pregnancy following total hysterectomy is a rare event. Ectopic pregnancy following supracervical hysterectomy can be explained in view of the remaining patent cervical canal. In cases of total hysterectom...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1983-07-01 00:00:00
abstract::The diagnosis and management of ovarian hemorrhage complicating anticoagulant therapy is discussed and a case presented. The patient, who had undergone mitral valve replacement and was receiving chronic anticoagulation treatment, was admitted with signs of intraperitoneal bleeding from a ruptured ovarian hematoma. Thi...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1982-10-01 00:00:00
abstract:BACKGROUND:The prognostic value of intra-operative peritoneal lavage cytology and chemotherapy was evaluated retrospectively. METHOD:Lavage cytology was performed in 257 patients. Prognosis was investigated in 85 of pT3 and pT4 patients with radical gastrectomy. Intra-operative chemotherapy was selected according to t...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:The infrequency of right-sided colonic diverticulitis prompted this presentation of our experiences, with emphasis on the diagnostic aspects. PATIENTS AND METHODS:Charts and documentation regarding 20 patients who underwent surgery for diverticulitis of the caecum and/or ascending colon over 22 years were revi...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::This series consists of seven patients with hydatid cysts of the pancreas; five females and two males, with an average age of 31 years. In a follow-up extending up to 33 years, about a 50% rate of correct preoperative diagnosis was recorded. The most sensitive and effective diagnostic modalities such as latex agglutin...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract::A 46-year-old man underwent living-donor liver transplantation and splenectomy for primary biliary cirrhosis. On postoperative day 22, cloudiness of ascites increased, and triglyceride concentration in ascites was as high as 1046 mg/dL. With a diagnosis of chylous ascites, total parenteral nutrition was started. Nine ...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/CC118.1
更新日期:2012-10-01 00:00:00