Abstract:
:We investigated the effect of RET c.2307T>G polymorphism on the outcomes of posterior sagittal neurectomy for Hirschsprung disease (PSNHD) procedure in Indonesia. Hirschsprung disease (HSCR) is a neurocristopathy characterized by absence of enteric ganglia along variable lengths of the intestine in neonates. The RET c.2307T>G polymorphism has been shown to be associated with HSCR. Many surgical techniques with some advantage and disadvantage were established for HSCR. We have conducted PSNHD in short-segment HSCR patients.Thirty-one nonsyndromic HSCR patients underwent PSNHD. The polymorphism was determined using PCR-RFLP in genomic DNA. The rate of enterocolitis and constipation outcomes following PSNHD were 6 (19%) and 4 (13%) patients, respectively. The RET c.2307T>G polymorphism did not influence either enterocolitis or constipation outcome following PSNHD at P value of 0.07 (OR = 0.28; 95% CI = 0.08-1.05) and 0.67 (OR = 0.58; 95% CI = 0.12-2.76), respectively. Our study suggested that RET c.2307T>G polymorphism may not affect outcomes of PSNHD procedure in Indonesia. Furthermore, a multicenter study with a larger sample size is necessary to clarify this result.
journal_name
Int Surgjournal_title
International surgeryauthors
Rochadi,Haryana SM,Sadewa AH,Gunadidoi
10.9738/INTSURG-D-14-00082.1subject
Has Abstractpub_date
2014-11-01 00:00:00pages
802-6issue
6eissn
0020-8868issn
2520-2456journal_volume
99pub_type
杂志文章abstract::Expanded polytetrafluoroethylene (Gore Tex) grafts were used for the replacement of the superior or inferior vena cava in dogs. When examined 2 weeks to 18 months after the replacement, the overall patency rate was 82%. If neither deformation nor narrowing of the graft on examination by cavagram had occurred within 14...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1981-07-01 00:00:00
abstract::The history of inguinal herniorrhaphy certainly presents some peculiar aspects. Until the 18th century this disease was studied with interest and found a place in the books of several important authors, but in practice it was treated by empiricists and barbers. We must recognize however that some of their surgical met...
journal_title:International surgery
pub_type: 历史文章,杂志文章
doi:
更新日期:1986-07-01 00:00:00
abstract::Results obtained with temporary ileal cecostomy in 23 patients are reported. Particular attention is given to the incidence of anastomotic leakage, morbidity, mortality, hospitalization and nursing. The results achieved were successful and, although the series presented is small, the authors suggest that this techniqu...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1982-10-01 00:00:00
abstract::In a group of 82 women with congenital or acquired uterine malformation (such as intrauterine adhesions or uterus myomatosus), cerclage was successfully performed according to the McDonald method. The percentage of term deliveries increased from 29.8% to 69.2% and the percentage of spontaneous abortions decreased from...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1977-04-01 00:00:00
abstract::Three-hundred and forty-five cases of perforated duodenal ulcer were managed by suture plication alone. Perforated acute ulcers have a better ultimate outlook in terms of mortality and morbidity as compared with perforated chronic ulcers, which have a higher incidence of reperforation and reoperation. It is suggested ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1982-10-01 00:00:00
abstract:BACKGROUND:Hydatid disease of the liver remains an important and challenging problem in rural areas. Although, surgery is considered the treatment of choice for hydatid disease of the liver, percutaneous drainage is an alternative treatment method for selected cases. The purpose of this study was to evaluate the result...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::To test whether serotonin release from the argentaffin cells of the intestinal tract can elicit peptic ulcer, rats were given intraduodenal infusions of N/10 and N/20 hydrochloric acid. Serotonin measured in the portal venous blood of rats which had had an intraduodenal infusion of N/20 HCl for five minutes was signif...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1976-06-01 00:00:00
abstract::No topic in the field of vascular surgery evokes more controversy than the management of the patient with asymptomatic carotid artery stenosis. The fact remains, however, that patients can and do develop stroke without any antecedent TIA, and there is no definite and predictable way to identify the stroke-prone group....
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1984-07-01 00:00:00
abstract::Laparoscopic surgery for malignant diseases is associated with a risk for port site recurrence (PSR), and this problem remains to be resolved. This study was performed to evaluate the role that Seprafilm and Interseed (TC7) play in the prevention of PSR, using a nude mouse model of PSR. Nude mice with 2-mm port sites ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2004-10-01 00:00:00
abstract::Hemobilia is the process of bleeding into the biliary tree and is an unusual cause of upper gastrointestinal hemorrhage. When this event results from a cystic artery pseudoaneurysm, it is a particularly rare phenomenon; fewer than 20 cases are described in the literature. Alongside the literature review, we report a c...
journal_title:International surgery
pub_type: 杂志文章,评审
doi:10.9738/CC52.1
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Laparoscopic herniorrhaphy (LH) shares the same repair principle as open preperitoneal prosthetic herniorrhaphy (PPH). Theoretically, the recurrence rate of LH for recurrent inguinal hernia will match the low recurrence rate of PPH (1.2-3%). METHODS:One-hundred forty-five cases of recurrent inguinal hernia ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1998-04-01 00:00:00
abstract::The authors describe the present surgical procedure for duodenal ulcer; this consists of vagotomy in association with resection of the antral mucosa, and sliding the fundus mucosa to cover the naked surface. The gastroduodenal junction is sewn as an enlarged Weimberg pyloroplasty. A series of 20 patients were operated...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Regarding the complications of peptic ulcer, a perforation remains the most important fatal complication. The aim of our retrospective study was to determine relations between postoperative morbidity and comorbid disease or perioperative risk factors in perforated peptic ulcer. In total, 239 patients who underwent eme...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/INTSURG-D-14-00187.1
更新日期:2015-05-01 00:00:00
abstract::Primary carcinoma of the male urethra accounts for less than 1% of malignancies in men. Mucinous adenocarcinoma of the urethra is extremely rare, and its biologic behavior is poorly understood. We present herein a rare case of mucinous urethral adenocarcinoma in a male patient with longstanding ulcerative colitis and ...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/INTSURG-D-13-00073.1
更新日期:2014-09-01 00:00:00
abstract::Crohn disease is a chronic, transmural, inflammatory disease of the gastrointestinal tract with unknown etiology. It can affect any part of the gastrointestinal tract and may cause fistula, stricture, or abscess formation with disease progression. The preoperative diagnosis and definite management of this rare complic...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/INTSURG-D-13-00038.1
更新日期:2014-03-01 00:00:00
abstract::Charnley's compression clamps have hastened the union of cancellous bones but not much success has been obtained in the slender shafts of cortical bones. The principles of biophysics show that a fracture site under compression acts as a hinge joint. If friction is increased in such "joints" along indicated axes, immob...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::To inhibit local recurrence of rectal cancer, it is very important to ensure that there is a sufficient circumferential resection margin. We evaluated pathology studies of combined radical resection of seminal vesicles in the treatment of rectal cancer. We analyzed data from 7 cases of combined radical resection of th...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/1362.1
更新日期:2011-01-01 00:00:00
abstract::Thirty four patients with funnel chest were operated on using the Zimmer plate and/or U shaped rod. There were no recurrences of the chest deformity and 78.6% were satisfied with the result. The low % VC significantly improved after the operation. Five cases had one of the following complications, massive bleeding fro...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract::Fracture of the penis is a rare injury, only 135 patients having been reported by 1985. Our recent experience with six patients who underwent emergency surgery, has been documented. The results of treatment were excellent with complete recovery of function. The study recommends operative management as the treatment of...
journal_title:International surgery
pub_type: 杂志文章,评审
doi:
更新日期:1988-01-01 00:00:00
abstract::Catheter-related nosocomial urinary tract infection in postoperative orthopedic and trauma patients was studied prospectively using nitrofuroxone-impregnated urinary catheters (study group) and regular silicone-coated Foley catheters. Fifty adults in each group were randomly assigned. In Group A, antibiotic-impregnate...
journal_title:International surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-07-01 00:00:00
abstract::Fifteen patients with 16 histologically verified heterotopic pancreas lesions were encountered at our department during a period of 22 years. The incidence was 0.25% of the findings of all abdominal operations during the same period. Heterotopic pancreas caused symptoms in 5 patients. All the remaining 10 patients wer...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Duodenoscopic sphincterotomy (DS) is a well established treatment for common bile duct (CBD) stones in post-cholecystectomy patients, but not in patients with gallbladder in situ. The main argument against the procedure in the latter set of patients has been that by performing it, one is leaving behind the diseased ga...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract::This preliminary study included five patients with a history of haematemesis resulting from rupture of oesophageal varices complicating schistosomal hepatic fibrosis. Simultaneous measurements were taken of the endoscopic variceal pressure (EVP) and the free portal pressure (FPP) obtained by the cannulation of a mesen...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1987-07-01 00:00:00
abstract::Seventy-seven colostomies were performed in 74 patients: 35 for high anorectal agenesis, 34 for Hirschsprung's disease, 2 for necrotizing enterocolitis, 2 for small left colon syndrome, and 1 for volvulus neonatorum with perforation. There were 55 boys and 19 girls with a mean age of 0.8 years. The different types of ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract::The indications, results and evaluation methods of lumbar sympathectomy are very controversial. The authors present their experience and results with phenol lumbar sympathectomy (PLS). PLS (Reid's technique) was carried out in 25 patients with severe peripheral arterial disease. Sympathetic tone abolition was achieved...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1983-04-01 00:00:00
abstract::Temporary closure of the abdomen with a synthetic mesh and multiple planned relaparotomies are the essentials of the modern strategy for treating severe intra-abdominal sepsis or pancreatic necrosis. One of the complications associated with mesh closure of the abdomen is facial necrosis at the wound edges leading to e...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::The purpose of this study is to introduce and evaluate a new technique of repairing bile ducts by the tubular gastric wall with a vascularized pedicle. Both the end-to-end bile duct repair and Roux-en-Y hepatoenterostomy have limitations in the treatment of benign bile duct strictures after cholecystectomy. There are ...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/INTSURG-D-14-00260.1
更新日期:2015-06-01 00:00:00
abstract::A follow-up examination was performed on 15 patients who had undergone esophagogastric resection or total gastrectomy for cancer an average of ten years earlier. Endoscopy was done in each case. None of the patients who had the esophagogastrostomy high in the esophagus had esophagitis. The diameter of the esophagogast...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1977-06-01 00:00:00
abstract::99mTc-MIBI-guided detection of abnormal parathyroid glands in primary hyperparathyroidism (1-HPT) has become a popular and effective technique, but its efficacy for detecting the ectopic glands of secondary hyperparathyroidism (2-HPT) is still controversial. Of the 2-HPT cases from 2000 to 2004, 14 ectopic parathyroid...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2009-04-01 00:00:00
abstract::Cutaneous metastasis from primary visceral malignancy is a relatively uncommon clinical entity, with a reported incidence ranging from 0.22% to 10% among various series. However, the presence of cutaneous metastasis as the first sign of a clinically silent visceral cancer is exceedingly rare. We describe here a case o...
journal_title:International surgery
pub_type: 杂志文章,评审
doi:10.9738/INTSURG-D-13-00070.1
更新日期:2014-07-01 00:00:00