Ovarian cancer in Oriental women from Singapore: disease pattern and survival.

Abstract:

:A retrospective analysis of 88 ovarian tumours diagnosed over five years (1980-1984) in multi-racial Singaporean Oriental women revealed 70 (79%) epithelial tumours (ET), 17 (8%) sex cordstromal (SCS), six (7%) germ cell (GCT) and five (6%) secondary (metastatic) (SEC) cancers. The racial proportions and histological types found in the study were very similar to those of all Singaporean women in the population. Of 70 ET, 33 (47%) were stage I, five (7%) stage II, 30 (43%) stage III and two (3%) stage IV. In 97% surgical resection of primary tumour with/without removal of the uterus and opposite ovary was performed, followed by adjuvant chemotherapy in 76% and complete follow-up in 98%. The 5-year actuarial survivals in ET were in stage I 84% (low malignant potential 100% and frank carcinomas 70%), stage II 60%, stage III 29% and 0% in stage IV, whereas of the others none with SCS but four with GCT and all five with SEC died of disease. Though the incidence of ovarian cancer is much lower in Oriental than Caucasian women the proportion of different histological types, stage at presentation and survival from ovarian cancer in Oriental women does not differ from that in Caucasians.

journal_name

Int Surg

journal_title

International surgery

authors

Singh P,Arunachalam I,Singh P,Tan BY,Tock EP,Ratnam SS

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

115-22

issue

2

eissn

0020-8868

issn

2520-2456

journal_volume

75

pub_type

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