Abstract：
:Induction of transplant tolerance is a clinically desirable goal. To provide unbiased insight into transplant tolerance, we analyzed gene expression profiling in peripheral blood mononuclear cells from recipients of living-donor liver transplants (LDLTs) who had retained an immune tolerance with a well-functioning graft for several years using cDNA microarray. The comparative analyses with nontransplanted normal healthy volunteers showed that the majority of reliable detected genes were similar, and 5.6% of the genes in the tested genome (of which 627 up-regulated and 90 down-regulated) were significantly regulated and specific to tolerant LDLT recipients, indicating a significant genetic feature for inducing and maintaining immune tolerance. Moreover, the expression of several selected genes was confirmed by semiquantitative reverse transcriptase-polymerase chain reaction, which correlated to microarray data. Our data indicated that cDNA microarray technology was useful for this application and provided many informative insights into transplant tolerance mechanism.
journal_name
Int Surgjournal_title
International surgeryauthors
Kawasaki M,Iwasaki M,Koshiba T,Fujino M,Hara Y,Kitazawa Y,Kimura H,Uemoto S,Li XK,Tanaka Ksubject
Has Abstractpub_date
2007-09-01 00:00:00pages
276-86issue
5eissn
0020-8868issn
2520-2456journal_volume
92pub_type
杂志文章abstract：:Obstructive jaundice in patients with chronic pancreatitis still constitutes a surgical problem deserving the attention of many specialized centers throughout the world. Out of a series of 149 patients operated upon for chronic pancreatitis, 45 (30.2%) with common duct stricture secondary to pancreatic disease have be...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1984-04-01 00:00:00
abstract：:Of the 365 surgical techniques performed on the aorto-iliac area in 354 patients, 448 extremities were revascularized by means of the insertion of a prosthesis as a by-pass, and 165 by thromboendarterectomy (TEA), either global or ilio-femoral. The patency rate at five years was 83% for prostheses, and 72% for TEAs, s...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1988-10-01 00:00:00
abstract：:A case of cardiac tamponade as the first manifestation of bronchogenic adenocarcinoma is presented. Diagnosis of metastatic pericarditis with effusion was made by echocardiography and cytology of the pericarditis fluid. Because of rapid recurrence of the effusion, a pericardial window was created. This operation was w...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Simultaneous pancreas and kidney transplantation (SPK) is considered an extremely effective and well-established therapeutic option for selected patients with end-stage renal disease (ESRD), secondary to type 1 diabetes. Vascular complications in pancreas transplantation are more common than in any other solid organ t...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2008-07-01 00:00:00
abstract：:Angiomyolipoma, a form of mixed mesenchymal tumor, a not uncommon tumor of the kidney, is rarely found in the liver. We report a case of angiomyolipoma of the liver in a 34-year-old woman, in whom diagnosis was made by computed tomography (CT), magnetic resonance imaging, superior mesenteric and celiac trunk angiograp...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：:The aim of this study was to determine the clinical presentation, morbidity, and mortality and to identify the factors that might affect the outcome of emergency repair in elderly patients. A study of 143 patients (> 65 years old) who underwent emergency surgical repair for incarcerated external hernias during the per...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：:From 1979 to 1987, 1103 thoracotomies were performed in patients with lung cancer: 824 (74.7%) radical resections, 141 (12.7%) palliative resections and 138 (12.5%) exploratory thoracotomies. Among the 965 patients who underwent resection, 539 patients were N0, 190 patients N1 and 236 patients N2. Among patients with ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:The records of 115 patients with stage D-2 prostate cancer treated with bilateral orchiectomy were reviewed to determine the effect of this procedure in previously untreated patients and in patients who had prior hormone therapy. Previously untreated patients survived 22.8 months while those who had prior hormone ther...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Horseshoe kidney is probably the most common renal fusion anomaly. With the continuous donor shortage, transplant surgeons tend to accept donors previously considered unsuitable. We present a successful case of en bloc horseshoe kidney transplant in a single recipient. The literature is reviewed. The use of horseshoe ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2000-07-01 00:00:00
abstract：:The aim of this study is to analyze the risk factors for complications and recurrence in pilonidal sinus disease. The prospective study consisted of 144 patients with pilonidal sinus disease who were operated on at Dicle University Medical Faculty, Department of General Surgery, between February 2008 and December 2010...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/CC86.1
更新日期：2012-07-01 00:00:00
abstract：:The aim of the earliest possible diagnosis of breast carcinoma achieved through the integration of clinical, mammographic, sonographic and cytologic data has determined an increased detection of breast lesions and a greater accuracy in their description. Nevertheless, the nature of some of these lesions cannot be well...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：:Gastroduodenal anastomosis is not routine during reoperation for stomal ulcers after primary Billroth II gastrectomy. It nevertheless is a sure way to prevent an increased peptic potential which is brought about by a duodenal bypass. We have reviewed the published cases and added three more, bringing the total to 47. ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1975-10-01 00:00:00
abstract：:This report illustrates the case of a 79-year-old woman in whom a severe type of rectus sheath hematoma was found during conservative therapy for myocardial infarction. Although establishing a correct diagnosis and initiating conservative therapy is usually considered the most appropriate management of this clinical e...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：:The management of the stenosis of the pancreaticojejunostomy is dictated by the state of the anastomosis and the residual pancreas, endocrine, and exocrine pancreatic function. We report a case of a 23-year-old woman who presented with recurrent attacks of acute pancreatitis. Four years ago, she was diagnosed with pan...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2008-05-01 00:00:00
abstract：:Radiofrequency ablation of the liver for primary and metastatic disease is used for patients who are not candidates for resection or in conjunction with resection. The technique is simple, and the morbidity rate is low. A case of intrahepatic pseudoaneurysm after radiofrequency ablation of a centrally located hepatoce...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2008-11-01 00:00:00
abstract：:The purpose of this study was to investigate prognostic significance of Dopamine and cAMP-Regulated neuronal Phosphoprotein 32 (DARPP-32) expression in primary colorectal cancer. The study material consisted of clinical and histopathological data of 100 patients operated for colorectal cancer between 1994 and 1997. Fo...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-14-00022.1
更新日期：2015-02-01 00:00:00
abstract：:We evaluated in retrospect the applicability of conservative hepatic resection for hepatocellular carcinoma (HCC) of cirrhotic patients. Eighty (14.6%) of 548 patients with HCC underwent liver resection over a period of 10 years in this hospital. They were divided into two groups according to surgical procedures. In g...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：:Catheter-related nosocomial urinary tract infection in postoperative orthopedic and trauma patients was studied prospectively using nitrofuroxone-impregnated urinary catheters (study group) and regular silicone-coated Foley catheters. Fifty adults in each group were randomly assigned. In Group A, antibiotic-impregnate...
journal_title：International surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-07-01 00:00:00
abstract：:The application of microsurgical neurolytic techniques in cases of peripheral nerve entrapments offers greater advantages than other techniques, as it allows a better understanding of the neural alterations. In most cases, a longitudinal epineurectomy is necessary to free the fascicles of the epineural fibrosis. Less ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1980-11-01 00:00:00
abstract：:Video-thoracoscopy was used to evaluate and manage patients after thoracic trauma. It was used in 29 patients. Indications included retained hemothorax in 16 patients, empyema in 11, evaluation for the source of thoracic bleeding in 1, and an airleak in 1. The mechanism of injury was blunt trauma in 8 cases, 10 with s...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：:In an attempt to assess the different methods of treatment of tumors of the esophagus we contacted 170 surgeons (in 1975-1976). Seventy-six (45%) answered a questionnaire concerning the surgical management of esophageal tumors, the reasons for non operability and non resectability, the place of radiotherapy, the valid...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1979-03-01 00:00:00
abstract：:It has been reported that avoidance of recurrences after laparoscopic ventral hernia repair (LVHR) depends on using sutures to secure the mesh. We developed a successful sutureless LVHR. The "Double Crown" LVHR using ePTFE mesh (overlap, 23 cm) was done in 140 cases. Tacks were placed 1 cm apart at the edge of the mes...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2005-07-01 00:00:00
abstract：:A 53-year-old man with multiple liver metastasis of esophageal cancer underwent four courses of chemotherapy. After four courses of chemotherapy, positron emission tomography showed progressive disease. Because it was difficult to control the cancer only by chemotherapy, we performed proton beam therapy (PBT) combined...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-13-00188.1
更新日期：2015-01-01 00:00:00
abstract：:We have devised a method of esophageal transection using a suture device. This method interrupts the esophageal varices directly. We have performed this operation in 30 cases with satisfactory results. Blood loss is minimal. The operation is both shorter and simpler than conventional technics. ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1977-08-01 00:00:00
abstract：:Regarding the complications of peptic ulcer, a perforation remains the most important fatal complication. The aim of our retrospective study was to determine relations between postoperative morbidity and comorbid disease or perioperative risk factors in perforated peptic ulcer. In total, 239 patients who underwent eme...
journal_title：International surgery
pub_type： 杂志文章
doi：10.9738/INTSURG-D-14-00187.1
更新日期：2015-05-01 00:00:00
abstract：:We report nine cases of adrenal cysts, treated in our hospital, between 1980 and 1990. The majority of the cases (5/9) were incidental findings on US and CT examinations. We operated on 4/9 cases because of their symptomatology or their size. Four other cases were managed conservatively; one last case was treated by p...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：:The authors describe the present surgical procedure for duodenal ulcer; this consists of vagotomy in association with resection of the antral mucosa, and sliding the fundus mucosa to cover the naked surface. The gastroduodenal junction is sewn as an enlarged Weimberg pyloroplasty. A series of 20 patients were operated...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:We have reported one case of a rare combination of multiple primary malignancies in the stomach, a leiomyosarcoma and an adenocarcinoma in a 72-year-old male. He also had a leiomyoma of the stomach and a cavernous hemangioma of the spleen. Since he has had two malignant and two benign tumors, it would appear that this...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1979-03-01 00:00:00
abstract：:During 1982-90 we changed the surgical treatment of acute necrotizing pancreatitis twice. The operative strategy consisted of early formal resection (n = 13) during 1982-84, early lavational surgery (n = 15) during 1985-87 and late necrosectomy (n = 17) during 1988-90. The mortality rate decreased from 54% to 40% and ...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:The proportion of patients on dialysis with multiple access procedures, failed transplant(s), or no suitable sites for conventional arteriovenous (AV) fistula is increasing. We report on 4 patients at our institution requiring unusual measures to achieve vascular access for dialysis. All 4 patients had temporary femor...
journal_title：International surgery
pub_type： 杂志文章
doi：
更新日期：2009-04-01 00:00:00
