Abstract:
:Two hundred and seven patients aged from 37 to 65 years with noninflammatory breast cancer treated by surgery without radiation were studied over a ten year period with a view to forecasting the prognosis on the basis of the immune status and treatment. The immunocompetence or immune status was studied in 121 patients by in vitro and in vivo pre and post-surgical skin tests. The immunostimulation or restoration of the immune status was conducted by the P 40 immunomodulator from the Pasteur Institute: in an experimental study whose results are based on modified Huggins model and take in to account the survival rate and the evaluation of tumor growth; in a subgroup of 86 patients, demonstrating that immunostimulation is effective in low-scores, improves tolerance to chemotherapy and increases the six year survival rate in high risk low-score patients. The results are encouraging enough to propose improving the survival rate in a prospective clinical study of early breast cancer treated by local and regional means using a protocol incorporating an immunostimulation based on the existing immunocompetence with interferon-induced reconversion of the target cells in the hope of specific stimulation.
journal_name
Int Surgjournal_title
International surgeryauthors
Reynier J,Bazin JC,Bizzini B,Villet R,Chany C,Leandri Ssubject
Has Abstractpub_date
1988-01-01 00:00:00pages
10-5issue
1eissn
0020-8868issn
2520-2456journal_volume
73pub_type
杂志文章abstract::Totally implantable access ports (TIAPs) are generally used in oncology. Few studies have addressed complications associated with the insertion site. A total of 233 consecutive oncology patients were enrolled to receive TIAP inserts via internal jugular vein (IJV) or subclavian vein (SV). Data on clinicopathologic par...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/INTSURG-D-13-00185.1
更新日期:2014-03-01 00:00:00
abstract::A case of carcinoid syndrome in a patient receiving treatment for a malignant non-B-cell tumor of the pancreas is presented, and a survival of >14 years is noted. The probable cause is discussed. The literature is reviewed. It was found that such a presentation is rare, and long-term survival in these cases exceedingl...
journal_title:International surgery
pub_type: 杂志文章,评审
doi:
更新日期:2009-01-01 00:00:00
abstract::The purpose of this study is to introduce and evaluate a new technique of repairing bile ducts by the tubular gastric wall with a vascularized pedicle. Both the end-to-end bile duct repair and Roux-en-Y hepatoenterostomy have limitations in the treatment of benign bile duct strictures after cholecystectomy. There are ...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/INTSURG-D-14-00260.1
更新日期:2015-06-01 00:00:00
abstract::This is a 1 year study on the use of a culdoscopic sterilization technique on 250 patients aged 25 or more with at least 4 children and at least 6 weeks Postpartum. Clinical examination was made to exclude tumors, infections, or endometriosis. The laparoscope was used for transvaginal female sterilization employing ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract::This preliminary study included five patients with a history of haematemesis resulting from rupture of oesophageal varices complicating schistosomal hepatic fibrosis. Simultaneous measurements were taken of the endoscopic variceal pressure (EVP) and the free portal pressure (FPP) obtained by the cannulation of a mesen...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1987-07-01 00:00:00
abstract::We made clinical trials of en bloc extended radical mastectomy (EXT) of a new type in 118 patients from 1980 through 1985. A variety of conventional radical mastectomies (RDL) were also performed in 105 patients from 1973 through 1985. A multivariate analysis was performed of the results to compare EXT and RDL. The re...
journal_title:International surgery
pub_type: 临床试验,杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Experimentally produced angulatory deformities of rat tibia with and without physeal injury were observed at two to three-week intervals for an eight-week period by x-ray studies, in order to estimate the spontaneous correctability of tibial deformity in growing rats. The results obtained were as follows: 1) In the re...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1980-07-01 00:00:00
abstract::Many patients die each year lacking only a functional small bowel to survive. The minimum amount of small intestinal absorptive surface required to sustain life varies from patient to patient. Prolonged survival with oral alimentation alone has been reported in a few patients with an intact duodenum and as little as 1...
journal_title:International surgery
pub_type: 杂志文章,评审
doi:
更新日期:1999-10-01 00:00:00
abstract::This is a review of ectopic localizations of the parathyroid gland in one case. A hard mobile mass (2 x 2.5 cm) was detected on the right side of the neck of a patient who had previously been given a diagnosis of hyperparathyroidism. Computed tomography showed an adenoma (25 x 35 mm) in the paratracheal region on the ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::The activities of cathepsin B, D and G, and their distribution in the walls of normal aorta and those of aneurysms of abdominal aorta were studied. The immunohistochemical reaction for these cathepsins was positive in the aneurysm wall both in the cells and in the extracellular matrix. It was more apparent than in nor...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract::Benign tracheal stenosis is responsible for considerable morbidity, and it is difficult to treat. Our objective is to present the results of surgical treatment. This was a retrospective chart review from the tertiary care center on Head and Neck Surgery in Hospital Ana Costa. We performed a retrospective review of 19 ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2008-11-01 00:00:00
abstract::The spleen in newborns, infants, and children is rarely involved in a variety of pathological processes. These processes may involve an isolated splenic disease or may be a part of a systemic illness. Renal vein thrombosis in infants of diabetic mothers has been reported. We report a case of a newborn with intestinal ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2002-07-01 00:00:00
abstract::Multiple primary malignant neoplasm is the occurrence of a second primary malignancy in the same patient within 6 months of the detection of first primary (synchronous), or 6 months or more after primary detection (metachronous). Multiple primary malignant neoplasms are not very frequently encountered in clinical prac...
journal_title:International surgery
pub_type: 杂志文章,评审
doi:10.9738/INTSURG-D-13-00056.1
更新日期:2014-01-01 00:00:00
abstract::The diagnosis and management of ovarian hemorrhage complicating anticoagulant therapy is discussed and a case presented. The patient, who had undergone mitral valve replacement and was receiving chronic anticoagulation treatment, was admitted with signs of intraperitoneal bleeding from a ruptured ovarian hematoma. Thi...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1982-10-01 00:00:00
abstract:PURPOSE:To develop a non-obese diabetic rat model for sleeve gastrectomy with modified jejunoileal bypass (SG/MJIB) and to investigate its effectiveness and safety for inducing diabetic control. MATERIALS AND METHODS:Thirty-five 13-week-old male Goto-Kakizaki rats were randomly assigned to the pair-fed to sham-operate...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/INTSURG-D-15-00162.1
更新日期:2015-07-16 00:00:00
abstract::Catheter-related nosocomial urinary tract infection in postoperative orthopedic and trauma patients was studied prospectively using nitrofuroxone-impregnated urinary catheters (study group) and regular silicone-coated Foley catheters. Fifty adults in each group were randomly assigned. In Group A, antibiotic-impregnate...
journal_title:International surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-07-01 00:00:00
abstract::The records of 115 patients with stage D-2 prostate cancer treated with bilateral orchiectomy were reviewed to determine the effect of this procedure in previously untreated patients and in patients who had prior hormone therapy. Previously untreated patients survived 22.8 months while those who had prior hormone ther...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::A retrospective analysis of 88 ovarian tumours diagnosed over five years (1980-1984) in multi-racial Singaporean Oriental women revealed 70 (79%) epithelial tumours (ET), 17 (8%) sex cordstromal (SCS), six (7%) germ cell (GCT) and five (6%) secondary (metastatic) (SEC) cancers. The racial proportions and histological ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
abstract::Immediate breast reconstruction with the transverse rectus abdominis musculocutaneous (TRAM) flap after skin-sparing mastectomy is becoming an increasingly performed procedure in patients with ductal carcinoma in situ, early invasive breast cancer, and prophylactic mastectomy. Through a periareolar approach, it is pos...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2001-10-01 00:00:00
abstract::The aim of the earliest possible diagnosis of breast carcinoma achieved through the integration of clinical, mammographic, sonographic and cytologic data has determined an increased detection of breast lesions and a greater accuracy in their description. Nevertheless, the nature of some of these lesions cannot be well...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract::The presence of the umbilical cord in the birth canal either by prolapse or as a funis presentation is a potential obstetrical catastrophe. The contact hysteroscope is a tool which permits rapid and decisive assessment of the position of the cord or of the presenting part. ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::The authors performed a total of 237 endolaser treatments for insufficiency of great and small saphenous veins and assessed 5-year results. It was found that this method, especially if performed with a 1470-nm-wavelength laser combined with instrumental removal of some lateral veins, was very effective. It was delicat...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2010-07-01 00:00:00
abstract::Paragangliomas or chemodectomas are neoplasms that arise from neural crest cells and histologically resemble their adrenal counterpart, the pheochromocytoma. Seventy-one percent of the extra-adrenal paragangliomas are located in the superior or inferior para-aortic area. This tumor usually presents as an abdominal mas...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::From April 1985 to March 1986 there were 48 cases of laser breast operations. Twelve cases of breast cancer were treated by modified radical mastectomy using a CO2 laser. Another twelve cases of breast cancer were treated conventionally using a scalped and electrocautery for the purpose of comparison. Laser surgery of...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1987-10-01 00:00:00
abstract::A case of cardiac tamponade as the first manifestation of bronchogenic adenocarcinoma is presented. Diagnosis of metastatic pericarditis with effusion was made by echocardiography and cytology of the pericarditis fluid. Because of rapid recurrence of the effusion, a pericardial window was created. This operation was w...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::During 1982-90 we changed the surgical treatment of acute necrotizing pancreatitis twice. The operative strategy consisted of early formal resection (n = 13) during 1982-84, early lavational surgery (n = 15) during 1985-87 and late necrosectomy (n = 17) during 1988-90. The mortality rate decreased from 54% to 40% and ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Sixteen cases of acute pyogenic pericarditis have been reviewed. Uncontrollable septic course, episodes of cardiac tamponade and failure of the nonsurgical regimen were the main indications for surgery. Medical management is often ineffective because of the relentless septic course, presence of thick, viscid pus and g...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
abstract::The present study was to evaluate the accuracy of bedside index for severity in acute pancreatitis (BISAP) in predicting the severity and prognoses of acute pancreatitis (AP) in Chinese patients. Clinical data for 497 patients with AP were analyzed retrospectively to compare BISAP with acute physiology and chronic hea...
journal_title:International surgery
pub_type: 杂志文章
doi:10.9738/0020-8868-98.1.6
更新日期:2013-01-01 00:00:00
abstract::The standard surgical approach to multiple polyposis has been a total proctocolectomy and an end ileostomy because of the premalignant nature of the disease. This operation has been successful, but has resulted in a significant amount of psychological trauma due to the presence of an abdominal stoma. For that reason, ...
journal_title:International surgery
pub_type: 杂志文章
doi:
更新日期:1985-10-01 00:00:00
abstract::The effectiveness of low-molecular weight heparin CY 216 in the prophylaxis of fatal pulmonary embolism in patients undergoing general surgery was assessed in a multicentre, double-blind, randomized, clinical trial against placebo. A total of 4,498 patients aged over 40 undergoing general surgery were enrolled in the ...
journal_title:International surgery
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1989-10-01 00:00:00