Abstract:
:A popular criterion of cell-cell communication in tissue cultures is dye coupling: the ability of the injected fluorescent dye of low molecular weight to be transferred from one cell to another. We report about a new factor which induces cell-to-cell dye coupling in previously uncoupled epithelial sheets. Paradoxically it is the standard fluorescent microscopy itself (that is, blue light of 320- to 480-nm wavelength) which induces rapid morphological alterations of cell culture followed by the transfer of fluorescent dye from one cell to another. Thus monitoring cell-cell dye coupling by fluorescent microscopy may itself induce the dye coupling in previously uncoupled epithelial cells.
journal_name
Exp Cell Resjournal_title
Experimental cell researchauthors
Sharovskaja YuYu,Chailakhjan LM,Margolis LBdoi
10.1016/0014-4827(88)90204-2subject
Has Abstractpub_date
1988-04-01 00:00:00pages
404-8issue
2eissn
0014-4827issn
1090-2422journal_volume
175pub_type
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