Abstract:
:POEMS syndrome, a paraneoplastic disorder, caused by plasma cell dyscrasia, is characterized by polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes. Calciphylaxis is a vasculopathy of subcutaneous arteries with calcification and skin ulceration, most commonly associated with end-stage renal disease. Calciphylaxis occurring in patients with POEMS syndrome is very rare; only 8 cases have been reported to date. We report the 9th case. A middle-aged woman with chronic inflammatory demyelinating polyneuropathy and monoclonal plasma cell proliferative disorder with IgA gammopathy presented with a 3-month history of multiple painful violaceous plaques with gangrenous necrosis and ulceration on the abdomen and extremities. The skin lesions worsened after surgical debridement and fasciotomy but improved with weekly intravenous bortezomib combined with thalidomide and dexamethasone for POEMS syndrome. The present case illustrates that effective control of the disease activity of POEMS syndrome may improve the surgical outcome of extensive skin necrosis in POEMS syndrome-associated calciphylaxis.
journal_name
Indian J Dermatoljournal_title
Indian journal of dermatologyauthors
Liu CH,Chen YC,Chen TY,Huang HW,Lee JYdoi
10.4103/ijd.IJD_492_18subject
Has Abstractpub_date
2020-11-01 00:00:00pages
516-518issue
6eissn
0019-5154issn
1998-3611pii
IJD-65-516journal_volume
65pub_type
abstract::Sturge-Weber syndrome is a rare sporadic condition of mesodermal phakomatosis, characterized by purple-colored flat cutaneous cranial (face) hemangiomas (most commonly along the trigeminal nerve), glaucoma and vascular lesions in the ipsilateral brain and meninges. Klippel-Trenaunay syndrome is also an uncommon mesode...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.91848
更新日期:2011-11-01 00:00:00
abstract::Acrokeratosis verruciformis of Hopf (AKV) is a rare genodermatosis presenting as multiple plane wart-like lesions symmetrically distributed on dorsum of hands and feet. Its pathogenesis is unknown. A case of 24 years old female is described with multiple hyperpigmented, hyperkeratotic papules on the left side of body ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.117324
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Existing remedies for controlling pseudofolliculitis barbae (PFB) are sometimes helpful; however the positive effects are often short lived. The only definitive cure for PFB is permanent removal of the hair follicle. AIMS:Our aim was to compare the efficacy of the Alexandrite laser with the intense pulsed l...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.57615
更新日期:2009-01-01 00:00:00
abstract::Since propranolol was accidentally discovered to induce involution of hemangiomas, it is being used by many clinicians with a favourable response. We present our experience with use of propranolol and report three infants with hemangiomas who were treated with propranolol. First infant had a marked involution of the l...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.94281
更新日期:2012-03-01 00:00:00
abstract::Pheohyphomycosis is a rare heterogeneous group of mycotic infections caused by dematiaceous (phaeoid) fungi affecting the skin, subcutaneous tissue, and central nervous system. Herein, we report a case of 29-year-old man with innocuous pustule over the right index finger. Examination revealed a subcutaneous swelling w...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.108083
更新日期:2013-03-01 00:00:00
abstract::Eruptive syringoma is a very rare variant of syringoma. It is a benign adnexal tumor of the intraepidermal portion of eccrine sweat ducts. Here we report a 32-year-old female presented with classical asymptomatic eruptive syringomas involving her face and extremities. ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.152586
更新日期:2015-03-01 00:00:00
abstract:INTRODUCTION:Familial glucocorticoid deficiency (FGD) is a rare autosomal recessive potentially life-threatening condition, characterized by glucocorticoid deficiency, preserved aldosterone/renin secretion, and secondary rise in plasma adrenocorticotropic hormone level. This occurs due to either mutation in adrenocorti...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_716_16
更新日期:2017-03-01 00:00:00
abstract::A 50-year-old woman had suffered from chronic pruritic plaque located on right retroauricular area for around 16 years, which was diagnosed as lichen simplex chronicus. Seventeen years ago, patient had multiple scalded areas distributed throughout the body and underwent autologous skin flap transplantation for the rig...
journal_title:Indian journal of dermatology
pub_type:
doi:10.4103/ijd.IJD_88_19
更新日期:2020-01-01 00:00:00
abstract:CONTEXT:Alopecia areata (AA) is a common form of localized, non-scarring hair loss. The etiopathogenesis of the disease is still unclear, but the role of autoimmunity is strongly suggested. AA is commonly associated with various autoimmune disorders; the most frequent among them is autoimmune thyroid disorders. AIM:To...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.123494
更新日期:2014-01-01 00:00:00
abstract::Basal cell carcinoma is the most common nonmelanoma skin cancer. Its occurrence in the perianal region is very rare. Awareness of its benign behavior in this region, in contrast to the earlier reports, is vital in its management. Local excision seems to provide adequate control. We are herewith reporting an extremely ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.62758
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:The ability of steroids to reduce the histamine wheal was used to assess the efficacy of topical clobetasol propionate with varying dilutions of emollients. AIM:To determine the wheal-suppressing ability of topical clobetasol with varying dilutions of emollient. MATERIALS AND METHODS:It was a double-blinde...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.87146
更新日期:2011-09-01 00:00:00
abstract::We report a 60-year-old man who presented with a 2-year history of painless red raised lesions involving the tongue and scrotum. Histopathology was suggestive of angiokeratoma. Oral angiokeratomas are most commonly found as a component of the generalized systemic disorder in Fabry's disease or fucosidosis. Our patient...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.96207
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Basement membrane (BM) is a thick sheet of extracellular matrix molecules, upon which epithelial cells attach. Various immunohistochemical studies in the past have been carried out but these advanced staining techniques are expensive and not feasible in routine laboratories. Although hematoxylin and eosin (H...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.159626
更新日期:2015-09-01 00:00:00
abstract::Psoriasis is a multi-factorial skin disease with a complex pathogenesis. Various factors which have been suggested to play a key role in the pathogenesis are T cells, antigen presenting cells (APC's), keratinocytes, Langerhans' cells, macrophages, natural killer cells, an array of Th1 type cytokines, certain growth fa...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.48977
更新日期:2009-01-01 00:00:00
abstract::Melasma is a notorious dermatosis, often resistant to treatment. Chemical peeling constitutes an acceptable option of management of melasma (of any type and duration). In this article, as a group of experts from Pigmentary Disorders Society (PDS) in collaboration with South Asian Pigmentary Forum (SPF), we have tried ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_490_17
更新日期:2017-11-01 00:00:00
abstract::Cancer metastases represent the most devastating aspect of malignancy, since the mortality of cancer patients is mainly related to the metastatic behavior of the primary neoplasm. Skin metastases are usually late events in the course of tumor progression. Excluding melanoma, the most common tumor to metastasize to the...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.91838
更新日期:2011-11-01 00:00:00
abstract::Artificially intelligent computer systems are used extensively in medical sciences. Common applications include diagnosing patients, end-to-end drug discovery and development, improving communication between physician and patient, transcribing medical documents, such as prescriptions, and remotely treating patients. W...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_421_20
更新日期:2020-09-01 00:00:00
abstract:Background:Fungi as a source of allergen are still largely neglected in basic research as well as in clinical practice. This study aimed to highlight the impact of fungal allergens in a group of patients suffering from atopic dermatitis (AD). Aims and Objectives:The evaluation of the sensitization to fungi in AD patie...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_493_17
更新日期:2018-09-01 00:00:00
abstract:INTRODUCTION:Cutaneous leishmaniasis (CL) is a parasitic disease which has different clinical forms. The aim of this study is to compare the response to leishmanin skin test (LST) in three forms of CL including plaque type, lupoid type, and sporotrichoid type. MATERIALS AND METHODS:This was a descriptive cross-section...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.110838
更新日期:2013-05-01 00:00:00
abstract:Context:Androgenic alopecia (AGA) is a hereditary androgen-dependent disorder, characterized by gradual conversion of terminal hair into miniaturized hair and defined by various patterns. Common age group affected is between 30 and 50 years. Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors that inc...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_526_16
更新日期:2019-01-01 00:00:00
abstract::Dermatitis neglecta is a condition that results from inadequate frictional cleansing leading to accumulation of corneocytes, sebum and sweat ultimately resulting in hyper-pigmented patch or verrucous plaque. Recognizing this condition avoids unnecessary, aggressive diagnostic and therapeutic procedures. Here we report...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.152525
更新日期:2015-03-01 00:00:00
abstract::Hamartomatous conditions of skin are comprised of variable composition of normal skin elements. They can present as nodular masses. They can be mistaken for neoplastic skin lesions. Folliculosebaceous cystic hamartoma is a rare skin condition seen in adults, commonly on head, neck and face region. Congenital variant i...
journal_title:Indian journal of dermatology
pub_type:
doi:10.4103/ijd.IJD_319_18
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Vitiligo is one of the disorder that has social impact. Both skin and mucous membrane show depigmentation in vitiligo. Depigmentation in oral cavity can be more easily observed and the patient can be given awareness regarding the condition if they are unaware of vitiligo elsewhere in their body and can be gu...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.147844
更新日期:2015-01-01 00:00:00
abstract::Dermatitis artefacta (DA) is a self-inflicted dermatological condition where the underlying motive is to assume a sick role. The act of self-harm is to discharge the inner sense of isolation and emotional distress, which is too great to endure. We, hereby, report five interesting cases of DA with varied presentations,...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.169139
更新日期:2015-11-01 00:00:00
abstract::"Wolf's isotopic response" refers to the occurrence of a new dermatosis at the site of previously healed dermatosis. A number of factors including viral, neural, vascular, and immunologic factors have been implicated in the causation of this peculiar response but none has been proven conclusively. Here, we report a ca...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.131401
更新日期:2014-05-01 00:00:00
abstract:INTRODUCTION:Hand, foot, and mouth disease (HFMD), an enteroviral disease has emerged as a major emerging infection in India. This is caused most commonly by enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) but can also be due to CVA4-10, CVA24, CVB2-5, and echovirus 18 (Echo18). Virological analysis of the cases o...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_381_17
更新日期:2017-09-01 00:00:00
abstract::A case of tuberculosis verrucosa cutis in an unusual site is being reported. The patient had presented with recurrence of a perianal growth which had been excised in the past. A histopathological study done during the recurrence confirmed tuberculosis. The patient's chest X-ray showed pulmonary tuberculosis, though he...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract::Benign epithelioid peripheral nerve sheath tumor, a rare entity is an umbrella term describing benign, neural origin tumors with epithelioid morphology. Clinically indistinguishable from other benign cutaneous lesions, histopathology offers the only source of accurate diagnosis. Morphologic mimics include many benign ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.117354
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Atopy-related illnesses such as atopic dermatitis and asthma are chronic illnesses, and children suffering from such illnesses are subjected to frequent absenteeism from school. Studies have shown that the performance of children with asthma was comparable to their healthy counterparts despite their absentee...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.70665
更新日期:2010-07-01 00:00:00
abstract:Background:Chronic spontaneous urticaria (CSU) is a skin disorder with an important immunologic profile. S100A8, S100A9, and S100A12 are the members of S100 family that have been reported to play important role in autoimmune diseases, but the characteristics of these three S100 members have not been defined in CSU. Ai...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_375_18
更新日期:2019-11-01 00:00:00