Abstract：
Purpose:Patients with gastric cancer who receive neoadjuvant therapy are staged before treatment (cStage) and after treatment (ypStage). We aimed to compare the prognostic reliability of cStage and ypStage, alone and in combination. Materials and Methods:Data for all patients who received neoadjuvant therapy followed by surgery for gastric adenocarcinoma from 2004 to 2015 were extracted from the National Cancer Database. Kaplan-Meier (KM)curves were used to model overall survival based on cStage alone, ypStage alone, cStage stratified by ypStage, and ypStage stratified by cStage. P-values were generated to summarize the differences in KM curves. The discriminatory power of survival prediction was examined using Harrell's C-statistics. Results:We included 8,977 patients in the analysis. As expected, increasing cStage and ypStage were associated with worse survival. The discriminatory prognostic power provided by cStage was poor (C-statistic 0.548), while that provided by ypStage was moderate (C-statistic 0.634). Within each cStage, the addition of ypStage information significantly altered the prognosis (P<0.0001 within cStages I-IV). However, for each ypStage, the addition of cStage information generally did not alter the prognosis (P=0.2874, 0.027, 0.061, 0.049, and 0.007 within ypStages 0-IV, respectively). The discriminatory prognostic power provided by the combination of cStage and ypStage was similar to that of ypStage alone (C-statistic 0.636 vs. 0.634). Conclusions:The cStage is unreliable for prognosis, and ypStage is moderately reliable. Combining cStage and ypStage does not improve the discriminatory prognostic power provided by ypStage alone. A ypStage-based prognosis is minimally affected by the initial cStage.
journal_name
J Gastric Cancerjournal_title
Journal of gastric cancerauthors
Kim G,Friedmann P,Solsky I,Muscarella P,McAuliffe J,In Hdoi
10.5230/jgc.2020.20.e41subject
Has Abstractpub_date
2020-12-01 00:00:00pages
385-394issue
4eissn
2093-582Xissn
2093-5641journal_volume
20pub_type
杂志文章abstract：:Gastric volvulus is an uncommon clinical entity. There are three types of gastric volvulus; organoaxial, mesenteroaxial and combined type. This condition can lead to a closed-loop obstruction or strangulation. Traditional surgical therapy for gastric volvulus is based on an open approach. Here we report a successful c...
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journal_title：Journal of gastric cancer
pub_type： 杂志文章,评审
doi：10.5230/jgc.2016.16.2.63
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abstract：PURPOSE:Reoperations after gastrectomy for gastric cancer are performed for many types of complications. Unexpected reoperations may cause mental, physical, and financial problems for patients. The aim of the present study was to evaluate the causes of reoperations and to develop a strategic decision-making process for...
journal_title：Journal of gastric cancer
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doi：10.5230/jgc.2013.13.4.242
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abstract：PURPOSE:Bone metastasis from stomach cancer occurs only rarely and it is known to have a very poor prognosis. This study examined the clinical characteristics and prognosis of patients who were diagnosed with stomach cancer and bone metastasis. MATERIALS AND METHODS:The subjects were 19 patients who were diagnosed wit...
journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2011.11.1.38
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abstract：PURPOSE:This study aimed to investigate the correlation between multiple early gastric cancer (MEGC) and multiple primary malignancies during the follow-up of patients with gastrectomy. MATERIALS AND METHODS:The number of primary tumors detected in other organs after gastrectomy for early gastric cancer (EGC) has been...
journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2017.17.e19
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journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2010.10.4.226
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abstract：PURPOSE:Despite the compelling scientific and clinical data supporting the use of early oral nutrition after major gastrointestinal surgery, traditional bowel rest and intravenous nutrition for several postoperative days is still being used widely after gastric cancer surgery. MATERIALS AND METHODS:A phase II study wa...
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doi：10.5230/jgc.2011.11.2.101
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abstract：Purpose:Fibrinogen and platelets have been reported to play important roles in tumorigenesis and cancer progression. The aim of this research was to investigate the combination of functions of fibrinogen, platelets, and mean platelet volume (MPV) in predicting the survival of patients with gastric cancer (GC). Materia...
journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2018.18.e36
更新日期：2018-12-01 00:00:00
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journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2018.18.e24
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journal_title：Journal of gastric cancer
pub_type： 杂志文章
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journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2013.13.2.73
更新日期：2013-06-01 00:00:00
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journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2017.17.e33
更新日期：2017-12-01 00:00:00
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journal_title：Journal of gastric cancer
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doi：10.5230/jgc.2014.14.1.63
更新日期：2014-03-01 00:00:00
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journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2014.14.2.123
更新日期：2014-06-01 00:00:00
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journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2012.12.3.179
更新日期：2012-09-01 00:00:00
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journal_title：Journal of gastric cancer
pub_type： 杂志文章,评审
doi：10.5230/jgc.2019.19.e29
更新日期：2019-09-01 00:00:00
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journal_title：Journal of gastric cancer
pub_type：
doi：10.5230/jgc.2012.12.4.258
更新日期：2012-12-01 00:00:00
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journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2015.15.1.29
更新日期：2015-03-01 00:00:00
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journal_title：Journal of gastric cancer
pub_type： 杂志文章,评审
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journal_title：Journal of gastric cancer
pub_type： 杂志文章
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journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2012.12.2.81
更新日期：2012-06-01 00:00:00
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journal_title：Journal of gastric cancer
pub_type： 杂志文章,评审
doi：10.5230/jgc.2016.16.1.1
更新日期：2016-03-01 00:00:00
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pub_type： 杂志文章
doi：10.5230/jgc.2010.10.4.155
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abstract：:Mixed neuroendocrine-nonneuroendocrine neoplasms (MiNENs) are a group of rare tumors previously known as mixed adenoneuroendocrine carcinomas (MANECs). The neuroendocrine component is high-grade and may consist of small-cell carcinoma or large-cell neuroendocrine carcinoma. The nonneuroendocrine component may consist ...
journal_title：Journal of gastric cancer
pub_type：
doi：10.5230/jgc.2018.18.e16
更新日期：2018-06-01 00:00:00
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journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2011.11.3.155
更新日期：2011-09-01 00:00:00
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journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2018.18.e4
更新日期：2018-03-01 00:00:00
abstract：:Few surgeons have adopted pancreaticoduodenectomy (PD) for the treatment of advanced gastric cancer (AGC) invading the pancreas or duodenum because it remains controversial whether its prognostic benefits outweigh the high morbidity rates in such advanced cases. However, recent technical advances have revived diverse ...
journal_title：Journal of gastric cancer
pub_type：
doi：10.5230/jgc.2019.19.e24
更新日期：2019-12-01 00:00:00
abstract：:Prostate cancer is the second most common cause of cancer death in men in the United States. The most common sites of metastasis include the bone, lymph nodes, lung, liver, pleura, and adrenal glands, whereas metastatic prostate cancer involving the gastrointestinal tract has been rarely reported. A 64-year-old Africa...
journal_title：Journal of gastric cancer
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abstract：PURPOSE:Recently, laparoscopy-assisted gastrectomy (LAG) has been widely accepted modality for early gastric cancer in Korea. The indication of LAG may be extended in an experienced institution. In our institution, the first case of laparoscopy-assisted gastrectomy (LAG) for gastric cancer was performed in May 1998. We...
journal_title：Journal of gastric cancer
pub_type： 杂志文章
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更新日期：2012-03-01 00:00:00
abstract：PURPOSE:Gastric cancer has a high incidence and mortality rate in Korea. Despite a growing older population and an increase in the number of older patients with gastric cancer, the older patients are not willing to undergo surgery due to their operative risks. Hence, to determine the clinical characteristics and outcom...
journal_title：Journal of gastric cancer
pub_type： 杂志文章
doi：10.5230/jgc.2011.11.4.200
更新日期：2011-12-01 00:00:00
