Abstract:
PURPOSE:This study aimed to investigate the correlation between multiple early gastric cancer (MEGC) and multiple primary malignancies during the follow-up of patients with gastrectomy. MATERIALS AND METHODS:The number of primary tumors detected in other organs after gastrectomy for early gastric cancer (EGC) has been increasing because of improved survival and surveillance programs. A total of 3,129 patients underwent radical gastrectomy for treatment of EGC at Samsung Medical Center from January 2000 to December 2005. Of these, 3,057 patients were selected and their medical records were retrospectively analyzed. RESULTS:Among the 3,057 patients, 148 (4.8%) had MEGC, 84.5% were male, 57.4% were over 60 years old, 42.6% had a macroscopic type EGC IIb main lesion, and 68.9% had well-differentiated tumors with a significantly high incidence of MEGC. There were no differences between patients with solitary early gastric cancer (SEGC) and those with MEGC with regard to overall survival or recurrence-free survival, but MEGC was an independent risk factor for metachronous primary malignancies in other organs (P=0.004, hazard ratio [HR]=2.444). CONCLUSIONS:MEGC is not a risk factor for poor prognosis after curative gastrectomy, but it is a risk factor for metachronous primary malignancies in other organs during postoperative follow-up; therefore, careful surveillance is needed.
journal_name
J Gastric Cancerjournal_title
Journal of gastric cancerauthors
Kim DH,Kim SM,Choi MG,Sohn TS,Bae JM,Kim Sdoi
10.5230/jgc.2017.17.e19subject
Has Abstractpub_date
2017-06-01 00:00:00pages
154-161issue
2eissn
2093-582Xissn
2093-5641journal_volume
17pub_type
杂志文章abstract:Purpose:We previously found that the histone methyltransferase suppressor of variegation, enhancer of zeste, trithorax and myeloid-nervy-deformed epidermal autoregulatory factor-1 domain-containing protein 3 (SMYD3) is a potential independent predictive factor or prognostic factor for overall survival in gastric cancer...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2017.17.e33
更新日期:2017-12-01 00:00:00
abstract::As the incidence of early gastric cancer increases, laparoscopic surgery has become one of the treatments of choice for gastric cancer. With the increase of laparoscopic surgery, the chance of discovering aberrant anatomy during the operation also increases. We present a case of laparoscopic total gastrectomy in gastr...
journal_title:Journal of gastric cancer
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doi:10.5230/jgc.2013.13.3.188
更新日期:2013-09-01 00:00:00
abstract:PURPOSE:Despite the compelling scientific and clinical data supporting the use of early oral nutrition after major gastrointestinal surgery, traditional bowel rest and intravenous nutrition for several postoperative days is still being used widely after gastric cancer surgery. MATERIALS AND METHODS:A phase II study wa...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2011.11.2.101
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:Information regarding antimicrobial prophylaxis (AMP) for gastric cancer surgery is limited. The present study investigated the efficacy of single-dose AMP for the prevention of surgical site infection (SSI) in patients undergoing gastrectomy for gastric carcinoma. MATERIALS AND METHODS:Between 2011 and 2013, ...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2014.14.3.156
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:To determine the diagnostic utility of a frozen section biopsy in patients undergoing endoscopic submucosal dissection (ESD) for early gastric neoplasms with obscure margins even with chromoendoscopy using acetic acid and indigo carmine (AI chromoendoscopy). MATERIALS AND METHODS:The lateral spread of early ga...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2011.11.3.155
更新日期:2011-09-01 00:00:00
abstract::We present a rare case of a gastric mixed adenoneuroendocrine tumor and review the related English literature. A 77-year-old Caucasian woman was admitted to our department with nausea, anorexia, weight loss, and anemia. Esophagogastroduodenoscopy showed a large (>7 cm) ulcerative mass in the greater curvature of the s...
journal_title:Journal of gastric cancer
pub_type:
doi:10.5230/jgc.2014.14.1.63
更新日期:2014-03-01 00:00:00
abstract:Purpose:Enhanced recovery after surgery (ERAS) protocols for gastric cancer patients have shown improved outcomes in Asia. However, data on gastric cancer ERAS (GC-ERAS) programs in the United States are sparse. The purpose of this study was to compare perioperative outcomes before and after implementation of an GC-ERA...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2018.18.e24
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:Gastric cancer has a high incidence and mortality rate in Korea. Despite a growing older population and an increase in the number of older patients with gastric cancer, the older patients are not willing to undergo surgery due to their operative risks. Hence, to determine the clinical characteristics and outcom...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2011.11.4.200
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the reliability and the clinical applicability of the adenosine-triphosphate-based chemotherapy response assay (ATP-CRA) as a method of determining in vitro chemosensitivity in patients with gastric cancer. MATERIALS AND METHODS:A total of 243 gastric cancer tissue ...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2010.10.4.155
更新日期:2010-12-01 00:00:00
abstract::Surgery is still considered to be the mainstay for the treatment of localized gastric cancer with negative margins (R0-resection) and an adequate lymph-node-dissection (D2-lymphadenectomy). Unfortunately, most cases of gastric cancer are only diagnosed at an advanced stage due to frequent recurrences after primary res...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2013.13.2.73
更新日期:2013-06-01 00:00:00
abstract::Pylorus-preserving gastrectomy (PPG) is a function-preserving surgery for the treatment of early gastric cancer (EGC), aiming to decrease the complication rate and improve postoperative quality of life. According to the Japanese gastric cancer treatment guidelines, PPG can be performed for cT1N0M0 gastric cancer locat...
journal_title:Journal of gastric cancer
pub_type: 杂志文章,评审
doi:10.5230/jgc.2016.16.2.63
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:Perioperative chemotherapy improves survival outcomes in locally advanced (LA) gastric cancer. MATERIALS AND METHODS:We retrospectively analyzed patients with LA gastric cancer who were offered perioperative chemotherapy consisting of epirubicin, oxaliplatin, and capecitabine (EOX) from May 2013 to December 20...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2017.17.e3
更新日期:2017-03-01 00:00:00
abstract::[This corrects the article on p. 176 in vol. 20, PMID: 32596001.]. ...
journal_title:Journal of gastric cancer
pub_type: 已发布勘误
doi:10.5230/jgc.2020.20.e31
更新日期:2020-09-01 00:00:00
abstract::Surgeons occasionally encounter a patient with a gastric cancer invading an adjacent organ, such as the pancreas, liver, or transverse colon. Although there is no established guideline for treatment of invasive gastric cancer, combined resection with radical gastrectomy is conventionally performed for curative purpose...
journal_title:Journal of gastric cancer
pub_type:
doi:10.5230/jgc.2015.15.3.214
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:Before expanding our indications for laparoscopic gastrectomy to advanced gastric cancer and adopting reduced port laparoscopic gastrectomy, we analyzed and audited the outcomes of laparoscopy-assisted distal gastrectomy (LADG) for adenocarcinoma; this was done during the adoptive period at our institution thro...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2015.15.1.29
更新日期:2015-03-01 00:00:00
abstract::Few surgeons have adopted pancreaticoduodenectomy (PD) for the treatment of advanced gastric cancer (AGC) invading the pancreas or duodenum because it remains controversial whether its prognostic benefits outweigh the high morbidity rates in such advanced cases. However, recent technical advances have revived diverse ...
journal_title:Journal of gastric cancer
pub_type:
doi:10.5230/jgc.2019.19.e24
更新日期:2019-12-01 00:00:00
abstract:Purpose:Although standard radical gastrectomy is recommended after noncurative resection of endoscopic submucosal dissection (ESD) for early gastric cancer in most cases, residual tumor and lymph node metastasis have not been identified after surgery. The aim of this study is to evaluate the feasibility of sentinel nod...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2019.19.e12
更新日期:2019-06-01 00:00:00
abstract::Mixed neuroendocrine-nonneuroendocrine neoplasms (MiNENs) are a group of rare tumors previously known as mixed adenoneuroendocrine carcinomas (MANECs). The neuroendocrine component is high-grade and may consist of small-cell carcinoma or large-cell neuroendocrine carcinoma. The nonneuroendocrine component may consist ...
journal_title:Journal of gastric cancer
pub_type:
doi:10.5230/jgc.2018.18.e16
更新日期:2018-06-01 00:00:00
abstract::Epstein-Barr virus-associated gastric carcinoma (EBVaGC) is one of the four subtypes of gastric carcinoma (GC), as defined by the novel classification recently proposed by The Cancer Genome Atlas. EBVaGC has several clinicopathological features such as longer survival and higher frequency of lymphoepithelioma-like car...
journal_title:Journal of gastric cancer
pub_type: 杂志文章,评审
doi:10.5230/jgc.2016.16.1.1
更新日期:2016-03-01 00:00:00
abstract:Purpose:For unresectable or initially metastatic gastric cancer, conversion surgery (CVS), after systemic chemotherapy, has received attention as a treatment strategy. This study evaluated the prognostic value of ypTNM stage and the oncologic outcomes in patients receiving CVS. Materials and Methods:A retrospective re...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2020.20.e20
更新日期:2020-09-01 00:00:00
abstract:Purpose:Fibrinogen and platelets have been reported to play important roles in tumorigenesis and cancer progression. The aim of this research was to investigate the combination of functions of fibrinogen, platelets, and mean platelet volume (MPV) in predicting the survival of patients with gastric cancer (GC). Materia...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2018.18.e36
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:Since there are no proven tumor markers that reflect the course of gastric cancer, carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) are commonly used alternatives. However, the degree of progression that corresponds to an increase in these markers, and the values of these markers at differe...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2014.14.2.123
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:Recently, laparoscopy-assisted gastrectomy (LAG) has been widely accepted modality for early gastric cancer in Korea. The indication of LAG may be extended in an experienced institution. In our institution, the first case of laparoscopy-assisted gastrectomy (LAG) for gastric cancer was performed in May 1998. We...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2012.12.1.18
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:The use of 18F-2-deoxy-2-fluoro-D-glucose positron emission tomography-computed tomography as a routine preoperative modality is increasing for gastric cancer despite controversy with its usefulness in preoperative staging. In this study we aimed to determine the usefulness of preoperative positron emission tom...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2012.12.3.179
更新日期:2012-09-01 00:00:00
abstract::Gastric volvulus is an uncommon clinical entity. There are three types of gastric volvulus; organoaxial, mesenteroaxial and combined type. This condition can lead to a closed-loop obstruction or strangulation. Traditional surgical therapy for gastric volvulus is based on an open approach. Here we report a successful c...
journal_title:Journal of gastric cancer
pub_type:
doi:10.5230/jgc.2015.15.2.147
更新日期:2015-06-01 00:00:00
abstract::Alpha-fetoprotein-Producing gastric cancer is associated with poor prognosis because of frequent liver and lymph node metastasis. We present a case with synchronous liver metastasis who survived for 5 years. A 69-year-old man with upper abdominal pain was referred to our hospital. Gastrointestinal endoscopy revealed a...
journal_title:Journal of gastric cancer
pub_type:
doi:10.5230/jgc.2013.13.1.58
更新日期:2013-03-01 00:00:00
abstract:Purpose:The guidelines for pathological evaluation of early gastric cancer (EGC) recommend wider section intervals for surgical specimens (5-7 mm) than those for endoscopically resected specimens (2-3 mm). Studies in surgically resected EGC specimens showed not negligible lymph node metastasis risks in EGCs meeting the...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2020.20.e14
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:Reoperations after gastrectomy for gastric cancer are performed for many types of complications. Unexpected reoperations may cause mental, physical, and financial problems for patients. The aim of the present study was to evaluate the causes of reoperations and to develop a strategic decision-making process for...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2013.13.4.242
更新日期:2013-12-01 00:00:00
abstract::Ewing's sarcoma is a neoplasm of the undifferenciated small round cells, which generally affects the bone and deep soft tissues of children and adolescents. We present a case of gastric Ewing's sarcoma; a 35-year-old female who had no symptoms. While she was at a routine medical checkup, a protruding mass in her gastr...
journal_title:Journal of gastric cancer
pub_type:
doi:10.5230/jgc.2012.12.4.258
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:Bone metastasis from stomach cancer occurs only rarely and it is known to have a very poor prognosis. This study examined the clinical characteristics and prognosis of patients who were diagnosed with stomach cancer and bone metastasis. MATERIALS AND METHODS:The subjects were 19 patients who were diagnosed wit...
journal_title:Journal of gastric cancer
pub_type: 杂志文章
doi:10.5230/jgc.2011.11.1.38
更新日期:2011-03-01 00:00:00