Abstract:
Background:Recently, SARS-CoV-2 virus with the D614G mutation has become a public concern due to rapid dissemination of this variant across many countries. Our study aims were (1) to report full-length genome sequences of SARS-CoV-2 collected from four COVID-19 patients in the Special Region of Yogyakarta and Central Java provinces, Indonesia; (2) to compare the clade distribution of full-length genome sequences from Indonesia (n = 60) from March to September 2020 and (3) to perform phylogenetic analysis of SARS-CoV-2 complete genomes from different countries, including Indonesia. Methods:Whole genome sequencing (WGS) was performed using next-generation sequencing (NGS) applied in the Illumina MiSeq instrument. Full-length virus genomes were annotated using the reference genome of hCoV-19/Wuhan/Hu-1/2019 (NC_045512.2) and then visualized in UGENE v. 1.30. For phylogenetic analysis, a dataset of 88 available SARS-CoV-2 complete genomes from different countries, including Indonesia, was retrieved from GISAID. Results:All patients were hospitalized with various severities of COVID-19. Phylogenetic analysis revealed that one and three virus samples belong to clade L and GH. These three clade GH virus samples (EPI_ISL_525492, EPI_ISL_516800 and EPI_ISL_516829) were not only located in a cluster with SARS-CoV-2 genomes from Asia but also those from Europe, whereas the clade L virus sample (EPI_ISL_516806) was located amongst SARS-CoV-2 genomes from Asia. Using full-length sequences available in the GISAID EpiCoV Database, 39 of 60 SARS-CoV-2 (65%) from Indonesia harbor the D614G mutation. Conclusion:These findings indicate that SARS-CoV-2 with the D614G mutation appears to become the major circulating virus in Indonesia, concurrent with the COVID-19 situation worldwide.
journal_name
PeerJjournal_title
PeerJauthors
Gunadi,Wibawa H,Marcellus,Hakim MS,Daniwijaya EW,Rizki LP,Supriyati E,Nugrahaningsih DAA,Afiahayati,Siswanto,Iskandar K,Anggorowati N,Kalim AS,Puspitarani DA,Athollah K,Arguni E,Nuryastuti T,Wibawa Tdoi
10.7717/peerj.10575subject
Has Abstractpub_date
2020-12-21 00:00:00pages
e10575issn
2167-8359pii
10575journal_volume
8pub_type
杂志文章相关文献
PeerJ文献大全abstract:Background:Hair follicles in cashmere goats are divided into primary and secondary hair follicles (HFs). HF development, which determines the morphological structure, is regulated by a large number of vital genes; however, the key functional genes and their interaction networks are still unclear. Although the vitamin D...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7230
更新日期:2019-07-03 00:00:00
abstract::In recent years, a massive mortality event has killed millions of sea stars, of many different species, along the Pacific coast of North America. This disease event, known as 'sea star wasting disease' (SSWD), is linked to viral infection. In one affected sea star (Pisaster ochraceus), previous work had identified tha...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1876
更新日期:2016-03-29 00:00:00
abstract::Phlorotannins are primary and/or secondary metabolites found exclusively in brown seaweeds, but their geographic distribution and abundance dynamic are not very well understood. In this study we evaluated the phlorotannin concentrations among and within-species of brown seaweeds in a broad latitudinal context (range o...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7379
更新日期:2019-08-14 00:00:00
abstract::A new species of the genus Mesacanthion Filipjev, 1927 was discovered during a survey of natural beaches of Jeju Island in South Korea. The new species Mesacanthion jejuensissp. nov. shares general morphology of the genus such as the outer labial and cephalic setae being situated at the middle of cephalic capsule, wel...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8023
更新日期:2019-11-18 00:00:00
abstract::Bcl-2 (B-cell lymphoma 2) protein is localized in the outer membrane of mitochondria, where it plays an important role in promoting cellular survival and inhibiting the actions of pro-apoptotic proteins. PRDM10 is a member of the PR/SET family of epigenetic regulators and may play a role in development and cell differ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6941
更新日期:2019-05-15 00:00:00
abstract::Herein, we identified the tomato SlMYB102 gene as a MYB family transcription factor of the R2R3-MYB subfamily. We additionally determined that the SlMYB102 promoter region contains photoresponsive, abiotic stress-responsive, and hormone-responsive regulatory elements, and we detected higher SlMYB102 expression in the ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.10059
更新日期:2020-10-07 00:00:00
abstract::The spatial learning skills of high and low stress juvenile mulloway (Argyrosomus japonicus) were tested in a dichotomous choice apparatus. Groups of fish were formed based on background blood cortisol levels and required to learn the location of a food reward hidden in one of two compartments. Low stress fish charact...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3445
更新日期:2017-06-08 00:00:00
abstract::Background. Physical, visual, chemical, and auditory cues signalling fighting ability have independently evolved in many animal taxa as a means to resolve conflicts without escalating to physical aggression. Facial width-to-height ratio (fWHR, i.e., the relative width to height of the face) has been associated with do...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1775
更新日期:2016-03-21 00:00:00
abstract::Histone deacetylases (HDACs) are key epigenetic factors in regulating chromatin structure and gene expression in multiple aspects of plant growth, development, and response to abiotic or biotic stresses. Many studies on systematic analysis and molecular function of HDACs in Arabidopsis and rice have been conducted. Ho...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8539
更新日期:2020-02-12 00:00:00
abstract:Background:Endometriosis (EMs) is a non-malignant gynecological disease, whose pathogenesis remains to be clarified. Recent studies have found that hypoxia induces epithelial-mesenchymal transition (EMT) as well as epigenetic modification in EMs. However, the relationship between EMT and demethylation modification unde...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9950
更新日期:2020-09-15 00:00:00
abstract::Healthy, older adults are widely reported to experience cognitive decline, including impairments in inhibitory control. However, this general proposition has recently come under scrutiny because ageing effects are highly variable between individuals, are task dependent, and are sometimes not distinguished from general...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8401
更新日期:2020-01-09 00:00:00
abstract:BACKGROUND:Mycobacterium avium subsp. hominissuis (MAH) is an emerging opportunistic human pathogen. It can cause pulmonary infections, lymphadenitis and disseminated infections in immuno-compromised patients. In addition, MAH is widespread in the environment, since it has been isolated from water, soil or dust. In rec...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.2833
更新日期:2017-01-03 00:00:00
abstract::Rao's quadratic diversity index is one of the most widely applied diversity indices in functional and phylogenetic ecology. The standard way of computing Rao's quadratic diversity index for an ecological assemblage with a group of species with varying abundances is to sum the functional or phylogenetic distances betwe...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5211
更新日期:2018-07-06 00:00:00
abstract::Marine sponges host complex microbial consortia that vary in their abundance, diversity and stability amongst host species. While our understanding of sponge-microbe interactions has dramatically increased over the past decade, little is known about how sponges and their microbial symbionts interact with viruses, the ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5625
更新日期:2018-10-17 00:00:00
abstract::We provided chimpanzees (Pan troglodytes) with the ability to improve the quality of food rewards they received in a dyadic test of inequity. We were interested to see if this provision influenced their responses and, if so, whether it was mediated by a social partner's outcomes. We tested eight dyads using an exchang...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.165
更新日期:2013-09-17 00:00:00
abstract::The objectives of this experiment were to determine the effects of graded dietary lead (Pb) concentrations on body weight and Pb concentrations in blood, hair, soft tissues, and urine from pigs and to generate equations for estimating daily Pb intake. Sixteen barrows with initial body weight 36.3 kg (standard deviatio...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3936
更新日期:2017-11-01 00:00:00
abstract::Allium tenuissimum L. is a widely distributed perennial herbaceous species in temperate and desert steppes. Relative to other wild Allium species, it produces unique sweet flavors, more biomass in arid and cold environments, and has generated greater interest for crop production. Successful crop establishment, however...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8866
更新日期:2020-04-07 00:00:00
abstract::Genome sequencing is rapidly being adopted in reference labs and hospitals for bacterial outbreak investigation and diagnostics where time is critical. Seven gene multi-locus sequence typing is a standard tool for broadly classifying samples into sequence types (STs), allowing, in many cases, to rule a sample out of a...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5233
更新日期:2018-07-31 00:00:00
abstract::Staurozoan classification is highly subjective, based on phylogeny-free inferences, and suborders, families, and genera are commonly defined by homoplasies. Additionally, many characters used in the taxonomy of the group have ontogenetic and intraspecific variation, and demand new and consistent assessments to establi...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1951
更新日期:2016-05-05 00:00:00
abstract::Female adders (Vipera berus) are "capital breeders" that exhibit delayed maturity and intermittent reproductive frequency. We studied the attainment of sexual maturity, the initiation of annual breeding in mature females, the energy and mortality costs associated with breeding, the length of the reproductive cycle and...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6912
更新日期:2019-05-09 00:00:00
abstract::The reliability of finite element analysis (FEA) in biomechanical investigations depends upon understanding the influence of model assumptions. In producing finite element models, surface mesh resolution is influenced by the resolution of input geometry, and influences the resolution of the ensuing solid mesh used for...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.988
更新日期:2015-06-02 00:00:00
abstract::Rhizoctonia solani causes the disease peanut sheath blight, involving symptoms of maceration and necrosis of infected tissue, mainly caused by cell-wall-degrading enzymes (CWDEs). This study investigated the production of CWDEs including polygalacturonase (PG), polymethyl-galacturonase (PMG), cellulase (Cx) and β-gluc...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5580
更新日期:2018-09-05 00:00:00
abstract::Circular RNA (circRNA) is an endogenous noncoding RNA with a covalently closed cyclic structure. Based on their components, circRNAs are divided into exonic circRNAs, intronic circRNAs, and exon-intron circRNAs. CircRNAs have well-conserved sequences and often have high stability due to their resistance to exonuclease...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5503
更新日期:2018-08-24 00:00:00
abstract::Understanding the physiological tolerances of ectotherms, such as thermal limits, is important in predicting biotic responses to climate change. However, it is even more important to examine these impacts alongside those from other landscape changes: such as the reduction of native vegetation cover, landscape fragment...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6252
更新日期:2019-01-10 00:00:00
abstract::Percent of body fat and physiological stress are important correlates to wildlife demographics. We studied winter percent of body fat and physiological stress levels for a declining elk (Cervus canadensis nelsoni) population in South Dakota, 2011-2013. We obtained percent of winter body fat, pregnancy status, lactatio...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7185
更新日期:2019-06-27 00:00:00
abstract::Irruptions of small consumer populations, driven by pulsed resources, can lead to adverse effects including the decline of indigenous species or increased disease spread. Broad-scale pest management to combat such effects benefits from forecasting of irruptions and an assessment of the optimal control conditions for m...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6146
更新日期:2018-12-20 00:00:00
abstract:Background:Banteng (Bos javanicus d'Alton 1823) are an endangered species, highly sensitive to habitat structure and quality. In many areas, banteng were extinct and needed to be reintroduced to restore their population. Thus, understanding the responses of body condition of reintroduced banteng to their habitat was im...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9041
更新日期:2020-04-23 00:00:00
abstract::White-handed gibbons produce loud and acoustically complex songs when interacting with their neighbours or when encountering predators. In both contexts, songs are assembled from a small number of units although their composition differs in context-specific ways. Here, we investigated whether wild gibbons could infer ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9477
更新日期:2020-08-03 00:00:00
abstract::The Hydroporus memnonius species group includes both widespread and range restricted diving beetle taxa in the western Palaearctic, some of which have been divided into a number of geographical subspecies. Of these, Hydroporus necopinatus is distributed in the far west of Europe, from central Spain to southern Britain...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3076
更新日期:2017-03-09 00:00:00
abstract::The MYB transcription factor family is one of the largest gene families playing regulatory roles in plant growth and development. The MYB family has been studied in a variety of plant species but has not been reported in Taxus chinensis. Here we identified 72 putative R2R3-MYB genes in T. chinensis using a comprehensi...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8473
更新日期:2020-02-17 00:00:00