Anatomical variations and morphometric properties of the circulus arteriosus cerebri in a cadaveric Malawian population.

Abstract:

BACKGROUND:Knowledge of the anatomy of the circulus arteriosus cerebri (CAC) is important in understanding its role as an arterial anastomotic structure involved in collateral perfusion and equalization of pressure, and may explain observed variations in neurovascular disease prevalences across populations. This study was aimed at understanding the anatomical configuration and morphometric properties of the CAC in Malawian population. MATERIALS AND METHODS:Brains were collected from 24 recently-deceased black Malawian human cadavers during medico-legal autopsies. Photographs of the CACs were taken using a camera placed at a 30 cm height from the base of the brain. Whole-circle properties and segmental vessel parameters were analyzed using the OSIRIS computer program, paying attention to completeness, typicality, symmetry, and segmental vessel diameters and lengths. RESULTS:69.57 % of the CACs exhibited the complete-circle configuration. Of these, 37.5 % were typical, representing an overall typicality prevalence of 26.09 %. Vessel asymmetry was observed in 30.43 % of cases. There were 7 cases of vessel aplasia and 12 cases of vessel hypoplasia. The posterior communicating artery (PcoA) was the most variable (with 12 variations), widest (7.67 mm) and longest (27.7 mm) vessel while the anterior communicating artery (AcoA) was the shortest (0.78mm). Both the AcoA and the PcoA were the narrowest vessels (0.67 mm) in this study. CAC variations in Malawian populations appeared to be similar to those observed in diverse populations. CONCLUSIONS:Anatomical variations of the circulus arteriosus cerebri exist in Malawian population and should be taken into consideration in clinical practice.

journal_name

Folia Morphol (Warsz)

journal_title

Folia morphologica

authors

Nyasa C,Mwakikunga A,Tembo LH,Dzamalala C,Ihunwo AO

doi

10.5603/FM.a2020.0142

subject

Has Abstract

pub_date

2020-12-17 00:00:00

eissn

0015-5659

issn

1644-3284

pii

VM/OJS/J/71499

pub_type

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