Abstract:
:This study was conducted to assess the effect of melatonin on the structure of testis and spermatogenesis dynamics in neonate vitrified testis grafts. Neonate vitrified testes, candidates for transplantation heterotopically to experiment or control groups, were warmed in thawing media which had or did not have a supplement of 100 μM melatonin, respectively. Following transplantation, melatonin (20 mg/ /kg/day) or saline solution was intraperitoneally injected into the treated and the non-treated groups, respectively. The initiating spermatogenesis, spermatogonia survival, and structure of tissue in the testis graft were examined. Cell apoptosis (TUNEL assay) and proliferation (Brdu assay) in germ cells were determined. Histological studies revealed the dynamic of the spermatogenesis process in the vitrified testis graft. However, dilation of the lumen accompanied by a disorganised epithelium in the non-treated group was higher than in the treated group. Furthermore, the proportion of apoptotic germ cells together with a reduced proportion of proliferated germ cells was higher in the non-treated group than in the treated group. Overall, the number of seminiferous tubules in the testes grafts of both groups remained steady. However, the non-treated testes grafts contained more damaged seminiferous tubules than the treated ones. The thickness of the seminiferous tubules was greater in the melatonin treated group than in the non-treated group. In fact, the thickness of germinal epithelium was significantly higher in the treated group than in the non-treated group. The study may show a positive effect from melatonin resulting in more grafts restoring puberty. Furthermore, the associated increase in the healthy number of seminiferous tubules suggests that melatonin may have a preventative ischaemia/antioxidant role and in fact may be useful to initiate the spermatogenesis process.
journal_name
Folia Morphol (Warsz)journal_title
Folia morphologicaauthors
Hemadi M,Zargar M,Sobhani A,Sobhani Asubject
Has Abstractpub_date
2011-05-01 00:00:00pages
95-102issue
2eissn
0015-5659issn
1644-3284journal_volume
70pub_type
杂志文章abstract::The aim of the study was to evaluate the physiological developmental changes of male rats' lumbar vertebrae during the first 22 days after birth. Morphology and mineralisation of lumbar vertebrae were evaluated using double-staining and digital radiography system, which allowed vertebral width and optical density to b...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2015.0068
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Leopardus geoffroyi is a Neotropical wild felid with wide distribution in the south of the South American continent. The objective was to investigate the skeletopy of the intumescentia lumbalis (IL) and conus medullaris (CM) from 11 specimens of L. geoffroyi collected dead on highways. MATERIALS AND METHODS...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2019.0061
更新日期:2020-01-01 00:00:00
abstract::Cyclo-oxygenase (COX), which catalyses the conversion of arachidonic acid to prostaglandin endoperoxide and prostanoids, is widely expressed in mammalian organs. The aim of the study was to evaluate the immunoexpression of the constitutive and inducible cyclo-oxygenase isoforms (COX-1 and COX-2 respectively) in the oe...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:The vertebral artery originates from the subclavian artery and is divided into four segments. The aim of this study is to investigate the anatomical variations in the course and branches of the vertebral artery. M: ATERIALS AND METHODS: : A research was performed via Pubmed database, using the terms; "variat...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2020.0022
更新日期:2020-02-19 00:00:00
abstract:BACKGROUND:The hippocampal formation (HF) is one of the most important parts of the brain in the magnetic resonance imaging (MRI) volumetric analysis in various domains, but not completely from all aspects, including the handedness. The aim of our study was to evaluate the possible differences in the volume of the righ...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.2015.0102
更新日期:2015-01-01 00:00:00
abstract::This paper describes a rare case of genetically determined dentin dysplasia type Iin 26-year-old male patient. The paper highlights anatomical and radiologicalaspects of dental abnormalities and emphasizes the significance of the educationof both general practitioners and paediatricians as regards referring patients w...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2019.0012
更新日期:2019-01-01 00:00:00
abstract::Investigations were carried out on 43 serially sectioned human embryos of developmental stages 18 to 23. The homogeneous interzone of the future knee joint is observed in embryos at stage 18. During stage 19 this interzone is differentiated into dense, intensively stained, peripheral parts, which are the primordia of ...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::The number of arteries providing blood supply for the thyroid gland as well as the origin of the superior thyroid and inferior thyroid arteries were examined in 132 fetuses from single pregnancies and in 144 fetuses from twin pregnancies, aging 4 to 9 months. Most frequently (81% cases) four thyroid arteries were obse...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::The aim of the paper is to present the most important neuroanatomical and neurophysiological studies concerning the phenomenon of sound localisation in space by people. The author analysed the available literature concerning this topic. The article presents different theories explaining the phenomenon of sound localis...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.2015.0002
更新日期:2015-01-01 00:00:00
abstract::The aim of the paper is computer transformation of the transversal research results of male (214) and female (178) genital internal organs (examined in 4 months's intervals) in a way enabling longitudinal evaluation. ...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Pain accompanies most of illnesses. Pain results in from activation of a specific sensory system and is not direct result of an illness. Pain system may be activated early in the fetal development before its projections will penetrate the frontal cortex. Therefore, painful experience may induce some physiological cons...
journal_title:Folia morphologica
pub_type: 杂志文章,评审
doi:
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Despite the fact that numerous reptile species are widely studied by the researchers, information describing the detailed structure of particular organs in many reptiles is missing. MATERIALS AND METHODS:The tongue of the sand lizard (Lacerta agilis) was examined under the light and scanning electron micros...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2018.0064
更新日期:2019-01-01 00:00:00
abstract::The infratemporal fossa is often the site of pathology or surgical intervention. We describe an unusual muscle found during the routine dissection of the right infratemporal fossa. The literature germane to this variable muscle, best described as a variant of the pterygoideus proprius, is reviewed. The clinician may c...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Spinosin, a major component of Samen Ziziphi spinosae, has been shown to modulate sedation and hypnosis; however, the underlying neuronal mechanisms of its stimulatory effects remain unclear. MATERIALS AND METHODS:In the present study, we injected spinosin (15 mg/kg) or saline into mice, which were killed a...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2019.0118
更新日期:2020-01-01 00:00:00
abstract::Although the cephalic vein follows a fairly consistent course, numerous variants have been reported. We found a rare anatomical presentation of the cephalic vein in a 43-year-old Korean male cadaver. The cephalic vein had anastomosed with the basilic vein and brachial vein at the level of the elbow, perforated the pec...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2015.0082
更新日期:2016-01-01 00:00:00
abstract::Ultrastructural response of photoreceptors to 10 days of treatment with reserpine and bromocryptine, and to 10 days of illumination, was studied. Treatment with isoproterenol was also applied in some experiments with continuous illumination. Treatment with bromocryptine and reserpine induced elongation of rod outer se...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The aim of the research was to examine the anatomy of the arterial system in the inguinal region, hip and thigh of Papio anubis. No description of this was found in the available scientific literature, although, at the same time, the baboon is considered to be a good animal model in biomedical research. Macroscopic an...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:The embryological connection between the dorsal and ventral pancreatic regions divides the pancreas into two segments. This anatomical dependence allows segmental pancreatic resection through the embryological fusion plane (EFP). The advantages of limited pancreatic resection are the preservation of the natu...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2019.0121
更新日期:2019-11-21 00:00:00
abstract:BACKGROUND:In this study, we investigated the relationship between the portal vein and hepatic artery variations and the remaining liver volume in living donors in liver transplantation. MATERIALS AND METHODS:In the study, triphasic abdominal CT images of 180 live liver donor candidates were analyzed retrospectively. ...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2020.0080
更新日期:2020-08-04 00:00:00
abstract::There is a paucity of information in the literature regarding the quadrate ligament and the information that does exist is extremely conflicting. We dissected 30 cadavers (60 sides) to determine the morphology and function of this enigmatic ligament. A quadrate ligament (thickening of the elbow joint capsule) was foun...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:It has been previously published that the frontal branch of the middle meningeal artery (MMA) is usually embedded in a bony canal (BC). Although the incidence of the BC was over 70%, this structure is currently omitted both in anatomical nomenclature and in most of the literature. We found the same gap perta...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2019.0098
更新日期:2020-01-01 00:00:00
abstract::Sternal foramina may pose a great hazard during sternal puncture, due to inadvertent cardiac or great vessel injury. They can also be misinterpreted as osteolytic lesions in cross-sectional imaging of the sternum. On the other hand, variant xiphoid morphology such as bifid, duplicated, or trifurcated may be mistaken f...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Tendinopathy of the long head of the biceps brachii tendon (LHBT) is one of the most common, painful conditions of the anterior part of the shoulder and often coexists with rotator cuff tears. Multifactorial aetiopathology of tendi-nopathy is poorly understood; however, several studies indicated that it is s...
journal_title:Folia morphologica
pub_type: 临床试验,杂志文章
doi:10.5603/FM.a2017.0093
更新日期:2018-01-01 00:00:00
abstract::Ultrastructural morphometric analysis of satellite cells of the diaphragm from one and 30-day-old rats was performed. The nuclear and cytoplasmic components of the cells were evaluated. The results obtained indicate that the satellite cells of one-day-old female rats are in a state of low activity. In 30-day-old anima...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Despite intensive research in the anatomical sciences for the last two centuries, some structures of the human body still remain controversial or incompletely described. We describe a new membranous fascial anatomical entity, which we refer to as the iliolumbar membrane (ILM). During the 2004-2005 academic semesters a...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2006-02-01 00:00:00
abstract::Histological studies of the brain, lungs, liver, kidneys, heart, and the spleen were carried out in mice previously infected with 6 pathogenic strains of free-living amoebae of the genus Acanthamoeba. The potential virulence of the strains studied was determined on the basis of re-isolation of the amoebae from the org...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2005-08-01 00:00:00
abstract::In this study an attempt was made to define the ways of the orifice of the superior thyroid gland to the internal jugular vein in human fetuses, basing on corrosion casts of blood vessels. It was found that most frequently, i.e. in 44% of cases, the superior thyroid gland formed bilaterally multi-level anastomoses wit...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Primary heart tumours in the paediatric population are very rare and they range from 0.01% to 0.04%. Most are benign lesions of which about half are rhabdomyomas. Rhabdomyoma tumour diagnosis is associated with a 75-80% risk of tuberous sclerosis complex (TSC). TSC are characterised with numerous changes of hamartoma-...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2017.0119
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The outcome of the autograft therapy for Parkinson's disease including autologous cells from adrenal medulla was disappointing. This could be attributed to the pathological process in Parkinson's disease affecting cells of the adrenal medulla. This study was performed to investigate the histopathological cha...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:10.5603/FM.a2016.0036
更新日期:2017-01-01 00:00:00
abstract::The arterial fibrous rings were investigated in human embryos aged 7 and 8 weeks under light and scanning electron microscopes. In the present study it was shown that the arrangement of collagen and formation of fibres changes rapidly within one week. In the 7(th) week there are no collagen fibres and the netlike fibr...
journal_title:Folia morphologica
pub_type: 杂志文章
doi:
更新日期:2010-08-01 00:00:00