Abstract:
:The aim of the present study was to determine to what degree acute exposure to cadmium affects the expression of CGRP, CT, SST and SYN in the C cells of the rat thyroid. Animals from 7 experimental groups received CdCl2 iv. in doses of 3.5, 3, 2.5, 2, 1.5, 1 and 0.5 mg/kg b.w. respectively, while the control animals were given 0.9% NaCl iv. 24 hours after the iv. administration of CdCl2, a correlation was found between a single dose of cadmium and the intensity of the immunocytochemical reactions for CGRP, CT, SST and SYN in C cells of the rat thyroid when compared to the control. The weakest immunocytochemical reactions were noted in C cells of the thyroid of rats from Groups I and II, their intensity gradually increasing in Groups III, IV and V in comparison to the control. The reaction intensity in animals of Groups VI and VII resembled those of the control.
journal_name
Folia Morphol (Warsz)journal_title
Folia morphologicaauthors
Czykier E,Moniuszko-Jakoniuk J,Sawicki Bkeywords:
subject
Has Abstractpub_date
2004-05-01 00:00:00pages
217-19issue
2eissn
0015-5659issn
1644-3284journal_volume
63pub_type
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journal_title:Folia morphologica
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