Treating pediatric colorectal patients in low and middle income settings: Creative adaptation to the resources available.

Abstract:

:Colorectal disease profiles for children in low- and middle-income settings (LMIC) are characterized by late presentation, increased complications and limited follow-up in many cases. There is a high prevalence of infectious conditions causing secondary colorectal disease such as Mycobacterium Tuberculosis(TB), Human Immunodeficiency Virus(HIV) and Human Papilloma Virus(HPV), which also impact the management of other primary colorectal conditions, such as wound-healing and intestinal anastomosis. Perineal trauma from sexual assault, motor vehicle or pedestrian accidents, burns, and traditional enemas are commonly encountered and may require adaptation of principles used in treatment of congenital anomalies such as Hirschsprung's disease and Anorectal Malformations for reconstruction. Endemic conditions in certain LMIC require further research to delineate underlying causes and optimize management, such as "African" degenerative visceral leiomyopathy, congenital pouch colon in the Indian subcontinent, and congenital H-type rectal fistulae prevalent in Asia. These unique disease profiles require creative adaptations of resources within poor healthcare infrastructure settings. These special challenges and pitfalls in colorectal care and complications of adverse socioeconomic conditions, are discussed.

journal_name

Semin Pediatr Surg

authors

Brisighelli G,Etwire V,Lawal T,Arnold M,Westgarth-Taylor C

doi

10.1016/j.sempedsurg.2020.150989

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

150989

issue

6

eissn

1055-8586

issn

1532-9453

pii

S1055-8586(20)30109-8

journal_volume

29

pub_type

杂志文章
  • Gene transfer to the tracheobronchial tree: implications for fetal gene therapy for cystic fibrosis.

    abstract::Gene transfer to the tracheobronchial tree has been an active area of investigation since the discovery of the genetic defect in the cystic fibrosis transmembrane conductance regulator over two decades ago. Cystic fibrosis (CF) is the most common lethal monogeneic disorder for which there is no cure short of lung tran...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2003.09.007

    authors: Keswani SG,Crombleholme TM

    更新日期:2004-02-01 00:00:00

  • Blunt cerebrovascular injury in children.

    abstract::Blunt cerebrovascular injury in children is an uncommon occurrence that if missed and left untreated can result in devastating long-term neurologic consequences. Diagnosis can be readily obtained by a computed tomographic angiogram of the head and neck. If confirmed, treatment with antithrombotic therapy dramatically ...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2017.01.003

    authors: Fenton SJ,Bollo RJ

    更新日期:2017-02-01 00:00:00

  • Respiratory failure and extracorporeal membrane oxygenation.

    abstract::Conventional treatment of respiratory failure involves positive pressure ventilation with high concentrations of inspired oxygen. If adequate gas exchange still cannot be achieved extracorporeal membrane oxygenation (ECMO) may be an option. The general indication for ECMO for respiratory insufficiency is a reversible ...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2007.10.006

    authors: Frenckner B,Radell P

    更新日期:2008-02-01 00:00:00

  • New tools in the treatment of motility disorders in children.

    abstract::Gastrointestinal motility disorders can develop in neurologically impaired children and those with congenital malformations of the gut. It is characterized by moderate to severe abdominal pain, vomiting, and failure to thrive. Antral dysmotility after fundoplication and increased sympathetic over activity are 2 factor...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2009.07.009

    authors: Carachi R,Currie JM,Steven M

    更新日期:2009-11-01 00:00:00

  • Ethics in the management of conjoined twins.

    abstract::In dealing with conjoined twins, we have adopted a pragmatic approach in balancing what is possible, parental wishes and the likely outcome for the children. We believe that separation where feasible should be undertaken but appreciate that a few parents may wish their children to remain joined. The advice that we giv...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章

    doi:10.1053/j.sempedsurg.2015.06.008

    authors: Spitz L

    更新日期:2015-10-01 00:00:00

  • Recent innovations in the management of fecal incontinence.

    abstract::The importance of having a reproducible scoring system to objectively assess the severity of fecal incontinence and its response to treatment is stressed, and a number of methods are described. The approach to conservative treatment and investigation is outlined. Recent advances in the surgical management of fecal inc...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/spsu.2002.31806

    authors: Darakhshan AA,Williams NS

    更新日期:2002-05-01 00:00:00

  • Acute abdomen. Special considerations for the neurologically and immunologically impaired child.

    abstract::The neurologically or immunologically impaired child suspected of having an acute abdomen presents a formidable challenge. However, a thorough understanding of the underlying pathophysiology of the disease on the normal host response to an intraabdominal disease permits early recognition and initiation of treatment. C...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章

    doi:

    authors: Bensard DD,Haase GM

    更新日期:1997-05-01 00:00:00

  • Nephron-sparing surgery in children with primary renal tumor: indications and results.

    abstract::Nephron-sparing surgery (NSS) is the treatment of choice for children with bilateral Wilms' tumor (WT), or with WT on a single kidney, or with WT and a disease of the contralateral kidney, or with benign kidney tumor. NSS is a reasonable alternative to nephrectomy in children at risk of metachronous WT, including chil...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2005.11.002

    authors: Cozzi DA,Zani A

    更新日期:2006-02-01 00:00:00

  • Predicting outcomes in congenital diaphragmatic hernia.

    abstract::Identification of CDH infant populations at high risk for mortality postnatally may help to develop targeted care strategies, guide discussions surrounding palliation and contribute to standardizing reporting and benchmarking, so that care strategies at different centers can be compared. Clinical prediction rules are ...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2017.04.010

    authors: Daodu O,Brindle ME

    更新日期:2017-06-01 00:00:00

  • The multi-disciplinary approach to adolescent bariatric surgery.

    abstract::The multi-disciplinary team is essential for the success of an adolescent bariatric surgical program. This article will describe the components of the team and their roles. Essential members include a pediatrician or pediatric subspecialist with an interest and expertise in adolescent obesity, a pediatric surgeon with...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2013.10.012

    authors: Wulkan ML,Walsh SM

    更新日期:2014-02-01 00:00:00

  • Jejunum for bridging long-gap esophageal atresia.

    abstract:OBJECTIVE:Exploring pros and cons of bridging long-gap esophageal atresia with an orthotopic jejunal pedicle graft. Retrospective series of 19 patients. METHODS:From 1988 through 2005, 19 patients with long-gap esophageal atresia received a jejunal graft. Median age at reconstruction was 76 days. The technique involve...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章

    doi:10.1053/j.sempedsurg.2008.10.007

    authors: Bax KM

    更新日期:2009-02-01 00:00:00

  • Current surgical management of Crohn's disease in childhood.

    abstract::Crohn's disease is a chronic transmural inflammatory disease that may involve any portion of the gastrointestinal tract. It is being reported with increasing frequency in children of all ages. The diagnosis of Crohn's disease in children is dependent on the clinical, radiological, endoscopic, and pathological material...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:

    authors: Telander RL,Schmeling DJ

    更新日期:1994-02-01 00:00:00

  • Blunt injury to solid abdominal organs.

    abstract::Injuries to the solid abdominal viscera (spleen, liver, kidney, pancreas) are common in children sustaining trauma by blunt mechanisms. Success with nonoperative management of these injuries has led to recent extensions of this approach to the management of higher-grade more complicated injuries typically treated oper...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2004.01.006

    authors: Keller MS

    更新日期:2004-05-01 00:00:00

  • The Swiss cheese model of adverse event occurrence--Closing the holes.

    abstract::Traditional surgical attitude regarding error and complications has focused on individual failings. Human factors research has brought new and significant insights into the occurrence of error in healthcare, helping us identify systemic problems that injure patients while enhancing individual accountability and teamwo...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章

    doi:10.1053/j.sempedsurg.2015.08.003

    authors: Stein JE,Heiss K

    更新日期:2015-12-01 00:00:00

  • Fetal surgery for spina bifida: past, present, future.

    abstract::Open spina bifida or myelomeningocele (MMC) is a common birth defect that is associated with significant lifelong morbidity. Little progress has been made in the postnatal surgical management of the child with spina bifida. Postnatal surgery is aimed at covering the exposed spinal cord, preventing infection, and treat...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2012.10.003

    authors: Adzick NS

    更新日期:2013-02-01 00:00:00

  • Classification of anorectal malformations--initial approach, diagnostic tests, and colostomy.

    abstract::The optimal surgical care of patients with imperforate anus begins with appropriate decision making in the critical newborn period. In most cases the decision to create a colostomy should be delayed until the infant is 18 to 24 hours old. Except in cases of a rectoperineal fistula, most neonates are best treated with ...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:

    authors: Shaul DB,Harrison EA

    更新日期:1997-11-01 00:00:00

  • Pediatric hepatic vascular tumors.

    abstract::Vascular liver tumors in the pediatric population can present a diagnostic dilemma. The most common hepatic vascular tumors are hepatic hemangiomas; however the differential diagnosis can also include other benign lesions and malignant masses. Management is unique to the type and nature of the specific lesion. Thus, c...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.sempedsurg.2020.150970

    authors: McGuire A,Fernandez-Pineda I,Fishman SJ,Dickie BH

    更新日期:2020-10-01 00:00:00

  • Managing radiation risk in the evaluation of the pediatric trauma patient.

    abstract::Pediatric trauma is usually a nonoperative experience for the pediatric general surgeon. The pediatric trauma surgeon resuscitates the child and then evaluates and triages the identified injuries. A common diagnostic tool is the computed tomography (CT) scan. Most children who require evaluation for significant trauma...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2010.06.004

    authors: Scaife ER,Rollins MD

    更新日期:2010-11-01 00:00:00

  • The pediatric surgeon and palliative care.

    abstract::Palliative care is now a core component of pediatric care for children and families who are confronting serious illness with a low likelihood of survival. Pediatric surgeons, in partnership with pediatric palliative care teams, can play a pivotal role in assuring that these patients receive the highest possible qualit...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2013.05.004

    authors: Feudtner C,Blinman TA

    更新日期:2013-08-01 00:00:00

  • Insights into medical management of pediatric intestinal failure.

    abstract::Medical management of children with Intestinal failure continues to evolve. The development of specialized teams focused on the management of these children has made the most significant impact in improving outcomes. Medical management strategies are centered on the provision of adequate fluid electrolytes and calorie...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2018.07.006

    authors: Oliveira SB,Cole CR

    更新日期:2018-08-01 00:00:00

  • New and exciting advances in pediatric colorectal and pelvic reconstructive surgery - 2021 update.

    abstract::Caring for children with colorectal and pelvic reconstructive needs is complex and requires a lifelong commitment from clinicians devoted to the field. There has been a myriad of advances that have improved care and it has become clear that an integrated, multi-disciplinary approach maximizes the goal of improving the...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.sempedsurg.2020.150992

    authors: Levitt MA

    更新日期:2020-12-01 00:00:00

  • Congenital diaphragmatic hernia: an overview.

    abstract::Understanding the complex multisystem dysfunction in the infant with a congenital hernia of the posterolateral diaphragm is still evolving and has changed radically during the last decade. The reduction in lung mass, in conjunction with surfactant deficiency and diminished compliance, leads to initial deficiencies in ...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:

    authors: Greenholz SK

    更新日期:1996-11-01 00:00:00

  • Delayed fistulization from esophageal replacement surgery.

    abstract::We present two patients who developed delayed fistulization following esophageal replacement surgery. The first is a 13-year-old child who, at the age of 3 years, underwent a trans-mediastinal colonic esophageal replacement for a refractory corrosive injury followed by a retrosternal reverse gastric tube after an earl...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章

    doi:10.1053/j.sempedsurg.2009.02.008

    authors: Abdalwahab A,Al Namshan M,Al Rabeeah A,Laberge JM

    更新日期:2009-05-01 00:00:00

  • Risk stratification and outcome determinants in gastroschisis.

    abstract::Selection of outcome determinants and risk stratification are necessary to identify patients at higher risk for morbidity and mortality. This facilitates human and material resource allocation and allows for improved family counseling. While several different factors, including prenatal ultrasonographic bowel features...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2018.08.007

    authors: Wissanji H,Puligandla PS

    更新日期:2018-10-01 00:00:00

  • Necrotizing enterocolitis: Pathophysiology from a historical context.

    abstract::Necrotizing enterocolitis (NEC) continues to afflict approximately 7% of preterm infants born weighing less than 1500g, though recent investigations have provided novel insights into the pathogenesis of this complex disease. The disease has been a major cause of morbidity and mortality in neonatal intensive care units...

    journal_title:Seminars in pediatric surgery

    pub_type: 历史文章,杂志文章,评审

    doi:10.1053/j.sempedsurg.2017.11.003

    authors: Hackam D,Caplan M

    更新日期:2018-02-01 00:00:00

  • Current management of hypertrophic pyloric stenosis.

    abstract::Hypertrophic pyloric stenosis (HPS) is a common condition affecting infants that presents with progressive projectile nonbilious vomiting. The pyloric portion of the stomach becomes abnormally thickened and manifests as gastric outlet obstruction. The cause is unknown. Pyloromyotomy remains the standard of treatment a...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2006.10.004

    authors: Aspelund G,Langer JC

    更新日期:2007-02-01 00:00:00

  • Long term complications and outcomes in omphalocele.

    abstract::After a diagnosis of omphalocele during pregnancy, questions regarding long-term prognosis are of primary importance for parents. It is imperative that their questions are answered with substantiated data to promote confident decisions for their children. They frequently express concerns regarding long-term survival, ...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2019.04.004

    authors: Baerg JE,Munoz AN

    更新日期:2019-04-01 00:00:00

  • Parathyroid conditions in childhood.

    abstract::This review of parathyroid surgery in children will briefly discuss parathyroid gland embryology and anatomy before focusing on the pathophysiology, clinical presentation, and treatment of hyperparathyroidism in children. Hyperparathyroidism (HPT) is the overproduction of PTH and it is rare in children, with an incide...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2014.03.003

    authors: Burke JF,Chen H,Gosain A

    更新日期:2014-04-01 00:00:00

  • Error traps and culture of safety in Hirschsprung disease.

    abstract::Hirschsprung disease affects many children every year around the world. Currently, there is an extensive menu of diagnostic methods, and surgical treatments. This situation compels the physicians to follow the rationale of these interventions. The comprehensive diagnosis and treatment of Hirschsprung disease need sing...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2019.04.013

    authors: De La Torre L,Wehrli LA

    更新日期:2019-06-01 00:00:00

  • Pediatric cardiac transplantation.

    abstract::Pediatric heart transplantation has undergone major changes over the past two decades, marked by a substantial improvement in survival, reduction in posttransplant complications, and enhancement in quality of life for transplant recipients. Actuarial survival has improved substantially in the last decade. Indications ...

    journal_title:Seminars in pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1053/j.sempedsurg.2006.03.011

    authors: Alkhaldi A,Chin C,Bernstein D

    更新日期:2006-08-01 00:00:00