Abstract：
:Identification of CDH infant populations at high risk for mortality postnatally may help to develop targeted care strategies, guide discussions surrounding palliation and contribute to standardizing reporting and benchmarking, so that care strategies at different centers can be compared. Clinical prediction rules are evidence-based tools that combine multiple predictors to estimate the probability that a particular outcome in an individual patient will occur. In CDH, a suitable clinical prediction rule can stratify high- and low-risk populations and provide the ability to tailor management strategies based on severity. The ideal prediction tool for infants born with CDH would be validated in a large population, generalizable, easily applied in a clinical setting and would clearly discriminate patients at the highest and lowest risk of death. To date, 4 postnatal major clinical prediction rules have been published and validated in the North American CDH population. These models contain variables such as birth weight, Apgar score, blood gases, as well as measures of pulmonary hypertension, and associated anomalies. In an era of standardized care plans and population-based strategies, the appropriate selection and application of a generalizable tool to provide an opportunity for benchmarking, policy creation, and centralizing the care of high-risk populations. A well-designed clinical prediction tool remains the most practical and expedient way to achieve these goals.
journal_name
Semin Pediatr Surgjournal_title
Seminars in pediatric surgeryauthors
Daodu O,Brindle MEdoi
10.1053/j.sempedsurg.2017.04.010subject
Has Abstractpub_date
2017-06-01 00:00:00pages
136-139issue
3eissn
1055-8586issn
1532-9453pii
S1055-8586(17)30049-5journal_volume
26pub_type
杂志文章,评审abstract：:The incidence and prevalence of childhood-onset inflammatory bowel diseases (IBD), including subtypes Crohn's disease and ulcerative colitis, have risen dramatically in recent years, and have emerged globally as important pediatric chronic diseases. Therefore, health care providers are more frequently encountering ver...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2017.10.010
更新日期：2017-12-01 00:00:00
abstract：:Neuroblastoma is a heterogenous disease, with solid tumors arising in the adrenal gland or paraspinal regions in young children. Neuroblastoma is unique, with varied presentation and prognosis based on primary location and tumor stage. Tumor behavior and response to treatment ranges from spontaneous regression to diss...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sempedsurg.2019.150859
更新日期：2019-12-01 00:00:00
abstract：:Understanding the complex multisystem dysfunction in the infant with a congenital hernia of the posterolateral diaphragm is still evolving and has changed radically during the last decade. The reduction in lung mass, in conjunction with surfactant deficiency and diminished compliance, leads to initial deficiencies in ...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：
更新日期：1996-11-01 00:00:00
abstract：:Hypertrophic pyloric stenosis (HPS) is a common condition affecting infants that presents with progressive projectile nonbilious vomiting. The pyloric portion of the stomach becomes abnormally thickened and manifests as gastric outlet obstruction. The cause is unknown. Pyloromyotomy remains the standard of treatment a...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2006.10.004
更新日期：2007-02-01 00:00:00
abstract：:There are many clinical situations of concern that may be unique to pediatric anesthesiologists. The author discusses four of the more common presentations: asthma, cystic fibrosis, anterior mediastinal masses, and latex allergy. Many such issues can be resolved before surgery by consultation with members of the opera...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章
doi：10.1016/s1055-8586(99)70009-0
更新日期：1999-02-01 00:00:00
abstract：:This article discusses how to investigate various surgical causes of vomiting. Particular emphasis is placed on plain radiographic, ultrasound, and contrast study findings. The article touches upon nineteen different diseases, and encompasses diseases found in neonates to adolescents. ...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2003.08.002
更新日期：2003-11-01 00:00:00
abstract：:Increased portal pressure is the product of both increased resistance to splanchnic flow through the liver and increased blood flow in the portal circuit. Although portal hypertension in children is less common than in adults, the important clinical end results are the same, ie, esophageal variceal hemorrhage, ascites...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：
更新日期：1992-05-01 00:00:00
abstract：:The management of conjoined twins falls into three distinct groups-non-operative, emergency separation and elective separation. Planning meetings involving all the personnel who will be required during the operation are held. The radiological findings are presented and the anaesthetic, nursing and intensive care requi...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章
doi：10.1053/j.sempedsurg.2015.06.004
更新日期：2015-10-01 00:00:00
abstract：:Pancreatic islet transplantation is a minimally invasive treatment that has the potential to prevent diabetes after total pancreatectomy for benign disease (islet autotransplantation) and to reverse diabetes in those with type 1 diabetes (islet allotransplantation). In both scenarios, the treatment involves extracting...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2012.05.012
更新日期：2012-08-01 00:00:00
abstract：:Necrotizing enterocolitis (NEC) is the leading cause of death from gastrointestinal causes in premature infants, and its overall survival has not improved in the past three decades. While the precise cause of NEC remains incompletely understood, we and others have shown that a major predisposing factor in the developm...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2013.01.003
更新日期：2013-05-01 00:00:00
abstract：:Survey methodologies enable researchers to obtain information not routinely captured in electronic medical records, including how delivery of surgical care is perceived through the lens of a child, a parent or caregiver, or a surgeon. Here we describe the approach to using surveys to aid pediatric surgery practice. Th...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2018.10.007
更新日期：2018-12-01 00:00:00
abstract：:Congenital obstructive uropathy is a relatively common developmental malformation, and severely affected fetuses die soon after birth from oligohydramnios-induced pulmonary hypoplasia or renal failure. Prenatal ultrasonography can reliably diagnose the specific anatomic defect, and using fetal urine sampling we can de...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：
更新日期：1993-05-01 00:00:00
abstract：:Progressive familial intrahepatic cholestasis (PFIC) and Alagille syndrome (AS) are conditions caused by either an autosomal recessive or an autosomal dominant genetic defect, and they are both characterized by cholestasis, jaundice, and severe debilitating pruritus refractory to medical management. Before the advent ...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.sempedsurg.2020.150946
更新日期：2020-08-01 00:00:00
abstract：:Nephron-sparing surgery (NSS) is the treatment of choice for children with bilateral Wilms' tumor (WT), or with WT on a single kidney, or with WT and a disease of the contralateral kidney, or with benign kidney tumor. NSS is a reasonable alternative to nephrectomy in children at risk of metachronous WT, including chil...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2005.11.002
更新日期：2006-02-01 00:00:00
abstract：:An examination of and recommendations regarding the approval process for medical devices are presented. The typical pathways and hurdles laid out by the Federal Food and Drug Administration (FDA) are discussed, and options for marketing and use of medical devices are addressed. The first step in the regulatory process...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2006.07.009
更新日期：2006-11-01 00:00:00
abstract：:Hirschsprung (HSCR) disease is a relatively common neonatal developmental disorder of the enteric nervous system and is characterized by the absence of ganglion cells in the myenteric and submucosal plexuses of the distal intestine. This results in absent peristalsis in the affected bowel, and the development of a fun...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章
doi：10.1053/j.sempedsurg.2004.10.027
更新日期：2005-02-01 00:00:00
abstract：:For most children, cancer has become a curable disease. With this increased survival, the late effects of the diagnosis of cancer and its therapy have assumed increased importance for these children. Multiple late effects of essentially all organ systems have been described in selected groups of survivors. These may b...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：
更新日期：1993-02-01 00:00:00
abstract：:Disorders of sexual development (DSDs) are relatively rare congenital conditions in which the development of the chromosomal, gonadal, or anatomic sex is atypical. Some conditions may not manifest until puberty or adulthood. The examination and workup of either an infant or an older patient with suspected DSD should b...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2015.01.009
更新日期：2015-04-01 00:00:00
abstract：:The use of laparoscopic and thoracoscopic procedures in children continues to increase. Thus, anesthesiologists are faced with an increasing number of children for whom anesthetic care is required during these procedures. Significant physiological alterations may occur that are related to patient positioning and the i...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：
更新日期：1993-08-01 00:00:00
abstract：:The optimal surgical care of patients with imperforate anus begins with appropriate decision making in the critical newborn period. In most cases the decision to create a colostomy should be delayed until the infant is 18 to 24 hours old. Except in cases of a rectoperineal fistula, most neonates are best treated with ...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：
更新日期：1997-11-01 00:00:00
abstract：:Hemangiomas, cystic hygromas, and teratomas are the most common bulky lesions presenting in the head and neck of infants, but cystic hygromas and teratomas are rare, and most hemangiomas are initially small. Historically, hemangiomas have been watched with the belief that they all involute with good results. Recogniti...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：
更新日期：1994-08-01 00:00:00
abstract：:Until the 1970s, bladder exstrophy was a frequently fatal birth defect that, at the very least, conferred a shortened life span with devastating consequences for afflicted patients. Beginning with the modern era of surgical management, survival has become routine, and now the focus is on optimizing a near-normal retur...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2011.01.001
更新日期：2011-05-01 00:00:00
abstract：:The salivary glands comprise three main pairs of glands (ie, the parotid, the submandibular, and the sublingual) and a number of minor glands found in the mucosa of the upper aerodigestive tract. Lesions may be inflammatory or obstructive in nature or may stem from granulomatous or neoplastic disease. As such, establi...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2006.02.004
更新日期：2006-05-01 00:00:00
abstract：:Management strategies for infants with very low birth weight (VLBW) who have abdominal wall defects essentially are the same as for those in larger infants. The authors favor primary closure in infants with gastroschisis, and have achieved this goal in 91% of infants since 1985. Treatment of infants with omphalocele i...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章
doi：10.1016/s1055-8586(00)70022-9
更新日期：2000-05-01 00:00:00
abstract：:A malignant tumor of striated muscle origin, rhabdomyosarcoma (RMS) is a childhood tumor that has benefited from nearly 30 years of multimodality therapy, culminating in a >70% overall 5-year survival. Prognosis for RMS is dependent on primary tumor site, age, completeness of resection, presence and number of metastat...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2016.09.011
更新日期：2016-10-01 00:00:00
abstract：:Even if no large comparative studies enable us to definitely confirm the potential advantages of minimal retroperitoneoscopic access surgery, this new technique is now expanding in pediatric urology and considered today as feasible and safe in well-trained hands. The technique is described in detail; the main indicati...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章
doi：10.1053/j.sempedsurg.2007.06.010
更新日期：2007-11-01 00:00:00
abstract：:After a short description of mediastinal anatomy and embryology, the authors illustrate the division of the mediastinum, based on criteria of either surgical anatomy or radiological anatomy. Lastly, they discuss the topographical distribution of the mediastinal masses in anterior, visceral, and posterior compartments ...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章
doi：10.1016/s1055-8586(99)70018-1
更新日期：1999-05-01 00:00:00
abstract：:Appendectomy has been the standard of care for appendicitis since the late 1800s, and remains one of the most common operations performed in children. The advent of data-driven medicine has led to questions about every aspect of the operation-whether appendectomy is even necessary, when it should be performed (timing)...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2016.05.003
更新日期：2016-08-01 00:00:00
abstract：:Conventional treatment of respiratory failure involves positive pressure ventilation with high concentrations of inspired oxygen. If adequate gas exchange still cannot be achieved extracorporeal membrane oxygenation (ECMO) may be an option. The general indication for ECMO for respiratory insufficiency is a reversible ...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1053/j.sempedsurg.2007.10.006
更新日期：2008-02-01 00:00:00
abstract：:Myelomeningocele (MMC) is a common birth defect that is associated with significant lifelong morbidity. Little progress has been made in the postnatal surgical management of the child with spina bifida. Postnatal surgery is aimed at covering the exposed spinal cord, preventing infection, and treating hydrocephalus wit...
journal_title：Seminars in pediatric surgery
pub_type： 杂志文章,评审
doi：10.1016/s1055-8586(03)00029-5
更新日期：2003-08-01 00:00:00
