Lactobacillus casei LC01 Regulates Intestinal Epithelial Permeability through miR-144 Targeting of OCLN and ZO1.

abstract：:Wild strain L-6 was subjected to combined mutagenesis, including UV irradiation, atmospheric and room temperature plasma, and ion beam implantation, to increase the yield of 1,3-dihydroxyacetone (DHA). With application of a high-throughput screening method, mutant Gluconobacter oxydans I-2-239 with a DHA productivity ...

journal_title：Journal of microbiology and biotechnology

authors： Lin X,Liu S,Xie G,Chen J,Li P,Chen J

更新日期：2016-11-28 00:00:00

abstract：:We previously reported that the CopA3 peptide (LLCIALRKK, D-form) originally isolated from the Korean dung beetle has antimicrobial and immunosuppressive effects. However, the high cost of producing the synthetic peptide, especially the D-form, has limited the development of CopA3 for therapeutic purposes. Here, we in...

journal_title：Journal of microbiology and biotechnology

authors： Yoon IN,Hong J,Zhang P,Hwang JS,Kim H

更新日期：2017-02-28 00:00:00

abstract：:Laccase- and peroxidase-free tyrosinase has commercial importance in the production of L-3, 4-dihydroxyphenylalanine (L-DOPA), which is mainly used in the treatment of Parkinson's disease. In the present study, isolation of an actinomycetes microbial strain capable of producing only tyrosinase is reported. Among all s...

journal_title：Journal of microbiology and biotechnology

authors： Sambasiva Rao KR,Tripathy NK,Mahalaxmi Y,Prakasham RS

更新日期：2012-02-01 00:00:00

abstract：:Platycodon grandiflorum root (Platycodi radix) saponins, platycosides, have been used as health supplements and food items for the treatment of respiratory disorders and pulmonary diseases. Deglycosylated saponins have been known to exert stronger biological effects than their glycosylated forms. In the present study,...

journal_title：Journal of microbiology and biotechnology

authors： Ju JH,Kang SH,Kim TH,Shin KC,Oh DK

更新日期：2020-06-28 00:00:00

abstract：:Bacillus pumilus is one of the most characterized microorganisms that are used for high-level production of select industrial enzymes. A novel B. pumilus SCU11 strain possessing high alkaline protease activity was obtained in our previous work. The culture supernatant of this strain showed efficient dehairing capabili...

journal_title：Journal of microbiology and biotechnology

authors： Wang C,Yu S,Song T,He T,Shao H,Wang H

更新日期：2016-11-28 00:00:00

abstract：:Enterobacter sakazakii may be related to outbreaks of meningitis, septicemia, and necrotizing enterocolitis, mainly in neonates. To reduce the risk of E. sakazakii in baby foods, thermal characteristics for Korean E. sakazakii isolates were determined at 52, 56, and 60 degrees C in saline solution, rehydrated powdered...

journal_title：Journal of microbiology and biotechnology

authors： Kim SH,Park JH

更新日期：2007-02-01 00:00:00

abstract：:The production and characterization of an active recombinant N-acetylgalactosamine-6-sulfate sulfatase (GALNS) in Escherichia coli BL21(DE3) has been previously reported. In this study, the effect of the signal peptide (SP), inducer concentration, process scale, and operational mode (batch and semi-continuous) on GALN...

journal_title：Journal of microbiology and biotechnology

authors： Hernández A,Velásquez O,Leonardi F,Soto C,Rodríguez A,Lizaraso L,Mosquera Á,Bohórquez J,Coronado A,Espejo Á,Sierra R,Sánchez OF,Alméciga-Díaz CJ,Barrera LA

更新日期：2013-05-01 00:00:00

abstract：:In this study, we investigated the potential of using sediment bioelectrochemical systems (SBESs) for in situ treatment of the water and sediment in brackish aquaculture ponds polluted with uneaten feed. An SBES integrated into a laboratory-scale tank simulating a brackish aquaculture pond was established. This test t...

journal_title：Journal of microbiology and biotechnology

authors： Pham HT,Tran HT,Vu LT,Dang HT,Nguyen TTT,Dang THT,Nguyen MTT,Nguyen HQ,Kim BH

更新日期：2019-07-28 00:00:00

abstract：:Glucosyl rubusosides were synthesized by two dextransucrases. LcDexT was obtained from Leuconosotoc citreum, that LlDexT was obtained from Leuconostoc lactis. LcDexT and LlDexT regioselectively transferred a glucosyl residue to the 13-O-glucosyl moiety of rubusoside with high yield of 59-66% as analyzed by TLC and HPL...

journal_title：Journal of microbiology and biotechnology

authors： Ko JA,Ryu YB,Park JY,Kim CY,Kim JS,Nam SH,Lee WS,Kim YM

更新日期：2016-03-01 00:00:00

abstract：:Filamentous fungi colonizing rice straw were collected from 11 different sites in Korea and were identified based on characterization of their morphology and molecular properties. The fungi were divided into 25 species belonging to 16 genera, including 14 ascomycetes, one zygomycete, and one basidiomycete. Fungal cell...

journal_title：Journal of microbiology and biotechnology

authors： Lee S,Jang Y,Lee YM,Lee J,Lee H,Kim GH,Kim JJ

更新日期：2011-12-01 00:00:00

abstract：:A series of thiobarbituric acid derivatives were constructed and evaluated for inhibitory activity on hepatitis C virus NS5B polymerase. In biochemical assays using purified viral polymerase and RNA template, the IC(50) value was improved to 0.41 microM from the original compound's 1.7 microM value. In HCV subgenomic ...

journal_title：Journal of microbiology and biotechnology

authors： Lee JH,Lee S,Park MY,Ha HJ,Myung H

更新日期：2010-03-01 00:00:00

abstract：:Copper-containing compounds are introduced into the environment through agricultural chemicals, mining, and metal industries and cause severe detrimental effects on ecosystems. Certain microorganisms exposed to these stressors exhibit molecular mechanisms to maintain intracellular copper homeostasis and avoid toxicity...

journal_title：Journal of microbiology and biotechnology

authors： Ng SP,Palombo EA,Bhave M

更新日期：2012-06-01 00:00:00

abstract：:In this study, a total of 58 different kinds of nuruk (a traditional Korean fermentation starter) were prepared, including 46 kinds of restored nuruk from ancient documents. Each nuruk was evaluated by analysis of its saccharification power, and the enzyme activities of glucoamylase, α-amylase, β-amylase, protease, an...

journal_title：Journal of microbiology and biotechnology

authors： Lee JE,Lee AR,Kim H,Lee E,Kim TW,Shin WC,Kim JH

更新日期：2017-05-28 00:00:00

abstract：:The infection of pandemic influenza viruses such as swine flu (H1N1) and avian flu viruses to the host cells is related to the following two factors: First, the surface protein such as HA (hemagglutinin) and NA (neuraminidase) of the influenza virus. Second, the specific structure of the oligosaccharide [sialic acid(a...

journal_title：Journal of microbiology and biotechnology

authors： Yoo ES

更新日期：2011-05-01 00:00:00

abstract：:Optimal conditions for a high cell density fermentation were investigated in a recombinant Escherichia coli producing salmosin, a platelet aggregation inhibitor. The optimized carbon and nitrogen sources were glycerol 10 g/l, yeast extract 30 g/l, and bacto-tryptone 10 g/l, yielding the dry cell weight (DCW) of 10.61 ...

journal_title：Journal of microbiology and biotechnology

authors： Seo MJ,Choi HJ,Chung KH,Pyun YR

更新日期：2011-10-01 00:00:00

abstract：:In the past, reactive oxygen species (ROS) have been considered a harmful byproduct of aerobic metabolism. However, accumulating evidence implicates redox homeostasis, which maintains appropriate ROS levels, in cell proliferation and differentiation in plants and animals. Similarly, ROS generation and signaling are in...

journal_title：Journal of microbiology and biotechnology

authors： Kim HJ

更新日期：2014-11-28 00:00:00

abstract：:The present study shows that DR1114 (Hsp20), a small heat shock protein of the radiationresistant bacterium Deinococcus radiodurans, enhances tolerance to hydrogen peroxide (H2O2) stress when expressed in Escherichia coli. A protein profile comparison showed that E. coli cells overexpressing D. radiodurans Hsp20 (EC-p...

journal_title：Journal of microbiology and biotechnology

authors： Singh H,Appukuttan D,Lim S

更新日期：2014-08-01 00:00:00

abstract：:In this study, three of the representative EDCs, 17beta-estradiol, bisphenol A, and styrene, were employed to find their mode of toxic actions in E. coli. To accomplish this, four different stress response genes, recA, katG, fabA, and grpE genes, were used as a representative for DNA, oxidative, membrane, or protein d...

journal_title：Journal of microbiology and biotechnology

authors： Kim YS,Min J,Hongz HN,Park JH,Park KS,Gu MB

更新日期：2007-08-01 00:00:00

abstract：:Benzo[a]pyrene (B[a]P), a polycyclic aromatic hydrocarbon, is a principal component of cigarette smoke. B[a]P can cause lung carcinogenesis and plays a key role in lung cancer progression. The role of B[a]P has been reported in lung cancer, but its effects on lung cancer stem cells (CSCs) have not been investigated. E...

journal_title：Journal of microbiology and biotechnology

authors： Bak Y,Jang HJ,Seo JH,No SH,Chae JI,Hong J,Yoon DY

更新日期：2018-03-28 00:00:00

abstract：:With the advantages of biocatalytic method, enzymes have been excavated for the synthesis of chiral amino acids by the reductive amination of ketones, offering a promising way of producing pharmaceutical intermediates. In this work, a robust phenylalanine dehydrogenase (PheDH) with wide substrate spectrum and high cat...

journal_title：Journal of microbiology and biotechnology

authors： Jiang W,Wang Y

更新日期：2020-01-28 00:00:00

abstract：:Organic solvent-tolerant (OST) enzymes are widely applied in various industries due to their activity and stability in organic solvents, higher substrate solubility, and increased stereo-selectivity. However, the criteria for identifying OST enzymes largely remain unresolved. In this study, we compared the amino acid ...

journal_title：Journal of microbiology and biotechnology

authors： Dachuri VK,Lee C,Jang SH

更新日期：2018-09-28 00:00:00

abstract：:Areca nut (AN) chewing is a habit in many countries in Central, Southern, and Southeast Asia. It is strongly associated with the occurrence of oral, pharyngeal, and esophageal cancer as well as systemic inflammation. However, the association between AN intake and the development of gastric lesions has not yet been ide...

journal_title：Journal of microbiology and biotechnology

authors： Lee J,Gunawardhana ND,Jang S,Choi YH,Illeperuma RP,Kim A,Su H,Hong YA,Kim JH,Kim J,Jung DW,Cha IH,Bak EJ,Cha JH

更新日期：2016-10-28 00:00:00

abstract：:It has been reported that Tat-SOD can be directly transduced into mammalian cells and skin and acts as a potential therapeutic protein in various diseases. To isolate the compound that can enhance the transduction efficiency of Tat-SOD, we screened a number of natural products. 3-O-[beta-D-Glucopyranosyl(1-->4)-alpha-...

journal_title：Journal of microbiology and biotechnology

authors： Lee SH,Kim SY,Kim DW,Jang SH,Lim SS,Kwon HJ,Kang TC,Won MH,Kang IJ,Lee KS,Park J,Eum WS,Choi SY

更新日期：2008-09-01 00:00:00

abstract：:MicroRNAs (miRNAs) are abundant in bovine milk and milk derived from other livestock, and they have functional roles in infants and in the secretion process of mammary glands. However, few studies have evaluated miRNAs in dairy processes, such as during cheese making and ripening. Thus, we investigated the characteris...

journal_title：Journal of microbiology and biotechnology

authors： Oh S,Park MR,Ryu S,Maburutse B,Kim JU,Kim Y

更新日期：2017-09-28 00:00:00

abstract：:As a provirus, polydnavirus has a segmented DNA genome on chromosome(s) of host wasp. It contains several genes in each segment that presumably play critical roles in regulating physiological processes of target insect parasitized by the wasp. A cysteine-rich protein 1 (CRP1) is present in the polydnavirus Cotesia plu...

journal_title：Journal of microbiology and biotechnology

authors： Barandoc K,Kim Y

更新日期：2009-06-01 00:00:00

abstract：:The total methylotrophic population associated with rice plants from different cultivars was enumerated at three different stages: vegetative, flowering, and harvesting. The bacterial population in the leaf, rhizosphere soil, endophytic in the stem and roots, and epiphytic in the florets and grains were determined fro...

journal_title：Journal of microbiology and biotechnology

authors： Madhaiyan M,Poonguzhali S,Sa T

更新日期：2007-10-01 00:00:00

abstract：:Ginseng and probiotics have anti-obesity effects in mice fed a high-fat diet (HFD). Absorption of ginsenoside and colonization of probiotics occur in the intestine. In this study, a mixture of fermented ginseng and two probiotics, Bifidobacterium longum BORI and Lactobacillus paracasei CH88, was administered to HFD-fe...

journal_title：Journal of microbiology and biotechnology

authors： Kang D,Li Z,Ji GE

更新日期：2018-05-28 00:00:00

abstract：:Abnormal melanin synthesis results in several hyperpigmentary disorders such as freckles, melanoderma, age spots, and other related conditions. In this study, we investigated the antimelanogenic effects of an extract from the microalgae Chlamydomonas reinhardtii (CE) and potential mechanisms responsible for its inhibi...

journal_title：Journal of microbiology and biotechnology

authors： Lee A,Kim JY,Heo J,Cho DH,Kim HS,An IS,An S,Bae S

更新日期：2018-12-28 00:00:00

abstract：:In this study, Bacillus licheniformis cells were immobilized by entrapment in calcium alginate beads and were used for production of alkaline protease by repeated batch process. In order to increase the stability of the beads, the immobilization procedure was optimized by statistical full factorial method, by which th...

journal_title：Journal of microbiology and biotechnology

authors： Mashhadi-Karim M,Azin M,Gargari SL

更新日期：2011-12-01 00:00:00

abstract：:This study compared the radioprotective effects of high-molecular-weight poly-gamma-glutamate (γ-PGA, average molecular mass 3,000 kDa) and a reduced form of glutathione (GSH, a known radioprotector) on calf thymus DNA damage. The radiation-induced DNA damage was measured on the basis of the decreased fluorescence int...

journal_title：Journal of microbiology and biotechnology

authors： Oh YJ,Kwak MS,Sung MH

更新日期：2018-04-28 00:00:00