当前位置： SCI文献检索 > JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA期刊下所有文献 > Diaphragmatic Dysfunction After Elective Cardiac Surgery: A Prospective Observational Study.

Diaphragmatic Dysfunction After Elective Cardiac Surgery: A Prospective Observational Study.

Abstract：

OBJECTIVES:To determine the incidence of postoperative diaphragm dysfunction as diagnosed by ultrasonography. DESIGN:Explorative prospective observational study. SETTING:University intensive care unit. PARTICIPANTS:One hundred consecutive patients undergoing elective cardiac surgery. INTERVENTIONS:Diaphragm ultrasound was performed the day before surgery during unassisted breath (D-1), at the first spontaneous breathing trial attempt (DSBT), 24 hours after surgery (D+1), and at intensive care unit (ICU) discharge (DICU). Diaphragm displacement, inspiratory and expiratory thickness, and the thickening fraction were measured at all timepoints. MEASUREMENTS AND MAIN RESULTS:Primary outcome was assessing the rate of postoperative diaphragm dysfunction, defined as a thickening fraction <20% at DSBT. Secondary outcomes were the number of difficult-to-wean patients, the need for rescue noninvasive ventilation, the reintubation rate, and the ICU length of stay. Thirty-eight patients showed diaphragm dysfunction at DSBT, which resolved over time. No differences in preoperative characteristics and comorbidities were found between patients who developed postoperative diaphragm dysfunction and patients without postoperative disorders. The duration of cardiopulmonary bypass (103 ± 34 v 55 ± 34 min; P < 0.001) was significantly associated with the development of postoperative diaphragm dysfunction. When compared with patients without postoperative diaphragm disorders, patients with diaphragm dysfunction were characterized by a higher rate of difficult weaning (32% v 5%; P < 0.001), lower extubation rate at 24 hours after surgery (50% v 92%; P < 0.001), and longer ICU length of stay (19 [16; 88] v 16 [15; 18] hours; P < 0.001). CONCLUSIONS:The incidence of postoperative diaphragm dysfunction after elective cardiac surgery is high and might contribute to prolonging ICU length of stay.

journal_name

J Cardiothorac Vasc Anesth

journal_title

Journal of cardiothoracic and vascular anesthesia

authors

Bruni A,Garofalo E,Pasin L,Serraino GF,Cammarota G,Longhini F,Landoni G,Lembo R,Mastroroberto P,Navalesi P,MaGIC (Magna Graecia Intensive care and Cardiac surgery) Group.

doi

10.1053/j.jvca.2020.06.038

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

3336-3344

issue

eissn

1053-0770

issn

1532-8422

pii

S1053-0770(20)30579-6

journal_volume

pub_type

杂志文章

在线工具

Diaphragmatic Dysfunction After Elective Cardiac Surgery: A Prospective Observational Study.