The effects of global normothermic hypoperfusion on the processed electroencephalogram in patients.

Abstract:

:This study examined the effects of global normothermic hypoperfusion on the compressed spectral array (CSA) processed electroencephalogram (EEG) during high-dose narcotic anesthesia. Fifteen patients undergoing cardiac electrophysiologic surgery were studied. The patients were anesthetized with a standard high-dose narcotic technique and then connected to a Nicolet Pathfinder I CSA EEG analysis system using seven subdermal electrodes in a modified International 10-20 configuration. There were 167 intervals of profound hypotension ranging from 8 to 96 seconds. During these periods the cerebral perfusion pressure was almost zero. Despite 38 intervals up to 32 seconds long, 6 of the 15 patients had no EEG changes. Overall, there were 36 (21.6%) ischemic EEG recordings. None of the patients developed neurological complications. The incidence of EEG changes was much lower than expected from other studies. Either the processed EEG was inherently insensitive, the high-dose narcotic masked the processed EEG effects of hypoperfusion, or the narcotic provided a previously unknown protective effect.

authors

Konstadt SN,Black S,Segil L,Blakeman B,Wilber D,Warf P,Stull C,Rao TL

doi

10.1016/1053-0770(91)90276-y

subject

Has Abstract

pub_date

1991-06-01 00:00:00

pages

214-7

issue

3

eissn

1053-0770

issn

1532-8422

pii

1053-0770(91)90276-Y

journal_volume

5

pub_type

杂志文章
  • High Ionized Calcium Concentration Is Associated With Prolonged Length of Stay in the Intensive Care Unit for Postoperative Pediatric Cardiac Patients.

    abstract:OBJECTIVE:There has been controversy regarding the beneficial effects of calcium on myocardial contractility and the harmful effects on myocardial cells, especially in children. The aim of this study was to investigate an association between ionized calcium concentration (iCa) and outcomes for pediatric patients after ...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2017.11.006

    authors: Kimura S,Iwasaki T,Oe K,Shimizu K,Suemori T,Kanazawa T,Shioji N,Kuroe Y,Matsuoka Y,Morimatsu H

    更新日期:2018-08-01 00:00:00

  • Metabolic syndrome exacerbates short-term postoperative cognitive dysfunction in patients undergoing cardiac surgery: results of a pilot study.

    abstract:OBJECTIVE:The authors tested the hypothesis that patients with metabolic syndrome are more likely to develop short-term cognitive dysfunction after cardiac surgery with cardiopulmonary bypass. DESIGN:A prospective study. SETTING:Veterans Affairs medical center. PARTICIPANTS:Fifty-six age- and education-balanced pati...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2010.06.008

    authors: Hudetz JA,Patterson KM,Iqbal Z,Gandhi SD,Pagel PS

    更新日期:2011-04-01 00:00:00

  • Right Ventricular Failure After Left Ventricular Assist Device Placement-The Beginning of the End or Just Another Challenge?

    abstract::Left ventricular assist device (LVAD) therapy has greatly improved outcomes in patients with end-stage heart failure. However, development of right ventricular failure (RVF) in LVAD recipients is associated with increased long- and short-term morbidity and mortality. The incidence of RVF after LVAD placement is diffic...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章,评审

    doi:10.1053/j.jvca.2018.07.047

    authors: Turner KR

    更新日期:2019-04-01 00:00:00

  • Patient Demographics and Extracorporeal Membranous Oxygenation (ECMO)-Related Complications Associated With Survival to Discharge or 30-Day Survival in Adult Patients Receiving Venoarterial (VA) and Venovenous (VV) ECMO in a Quaternary Care Urban Center.

    abstract:OBJECTIVE:Investigate how a multitude of patient demographics and extracorporeal membranous oxygenation (ECMO)-related complications affect 30-day survival or survival to discharge. DESIGN:Retrospective observational study. SETTING:Urban university hospital, quaternary care center. PARTICIPANTS:Patients who underwen...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2018.08.193

    authors: Kaushal M,Schwartz J,Gupta N,Im J,Leff J,Jakobleff WA,Leyvi G

    更新日期:2019-04-01 00:00:00

  • A Retrospective Analysis of the Variability in Case Duration for Aortic Valve Replacement and Association With Hospital Facility Types.

    abstract:OBJECTIVE:Currently, there are no large-scale studies that compare differences in case duration of aortic valve replacements (AVRs). The primary objective of this study was to determine associations of hospital facility type, geographic location, case volume per year, and time of day with duration of valve replacement ...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2017.06.039

    authors: Gabriel RA,Fergerson BD,Brovman EY,Dutton RP,Urman RD

    更新日期:2018-04-01 00:00:00

  • Laryngeal mask airway for therapeutic fiberoptic bronchoscopic procedures.

    abstract::These cases illustrate the advantages of the laryngeal mask as compared with an endotracheal tube or oxygen face mask for selected patients undergoing therapeutic bronchoscopic procedures. The advantages include a larger internal diameter allowing easier passage of instruments, reduced work of breathing, lack of disco...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1016/s1053-0770(05)80017-5

    authors: Birmingham B,Mentzer SJ,Body SC

    更新日期:1996-06-01 00:00:00

  • Modified rapid shallow breathing index adjusted with anthropometric parameters increases predictive power for extubation failure compared with the unmodified index in postcardiac surgery patients.

    abstract:OBJECTIVE:The aim of this study was to determine the best predictors of successful extubation after cardiac surgery, by modifying the rapid shallow breathing index (RSBI) based on patients' anthropometric parameters. DESIGN:Single-center prospective observational study. SETTING:Two general intensive care units at a s...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2014.06.022

    authors: Takaki S,Kadiman SB,Tahir SS,Ariff MH,Kurahashi K,Goto T

    更新日期:2015-02-01 00:00:00

  • The operating surgeon is an independent predictor of chest tube drainage following cardiac surgery.

    abstract:OBJECTIVES:Bleeding into the chest is a major cause of blood transfusion and adverse outcomes following cardiac surgery. The authors investigated predictors of bleeding following cardiac surgery to identify potentially correctable factors. DESIGN:Data were retrieved from the medical records of patients undergoing card...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2013.09.010

    authors: Dixon B,Reid D,Collins M,Newcomb AE,Rosalion A,Yap CH,Santamaria JD,Campbell DJ

    更新日期:2014-04-01 00:00:00

  • The Impact of Initiation of an Intensivist-Led Patient Management Protocol on Outcomes After Cardiac Surgery.

    abstract:OBJECTIVES:Prolonged intensive care unit stay after cardiac surgery is associated with high mortality. The aim of this study was to evaluate the impact of the introduction of a quality improvement program under the supervision of an intensivist on the long-term mortality of high-risk patients with prolonged intensive c...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2020.12.048

    authors: Kogan A,Kassif Y,Frogel J,Levin S,Ram E,Peled Y,Raanani E,Sternik L

    更新日期:2021-01-04 00:00:00

  • CHA2DS2-VASc Score and In-Hospital Mortality in Critically Ill Patients With New-Onset Atrial Fibrillation.

    abstract:OBJECTIVE:To examine the role of the CHA2DS2-VASc (Congestive heart failure; Hypertension; Age ≥75 years [doubled]; Diabetes; previous Stroke, transient ischemic attack, or thromboembolism [doubled]; Vascular disease; Age 65-75 years; and Sex category) score as a prognostic marker of in-hospital mortality in critically...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2019.11.044

    authors: Karamchandani K,Schoaps RS,Abendroth T,Carr ZJ,King TS,Bonavia A

    更新日期:2020-05-01 00:00:00

  • Critical Review and Meta-Analysis of Postoperative Sedation after Adult Cardiac Surgery: Dexmedetomidine Versus Propofol.

    abstract:OBJECTIVE:To evaluate reports from the published literature of all randomized clinical trials (RCT) comparing postoperative sedation with dexmedetomidine versus propofol in adult patients, after open cardiac surgery. DESIGN:A computerized search on Medline, EMBASE, Web of Science, and Agency for Healthcare Research an...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2020.10.022

    authors: Abowali HA,Paganini M,Enten G,Elbadawi A,Camporesi EM

    更新日期:2020-10-17 00:00:00

  • Association Between Motor-Evoked Potentials and Spinal Cord Damage Diagnosed With Magnetic Resonance Imaging After Thoracoabdominal and Descending Aortic Aneurysm Repair.

    abstract:OBJECTIVES:The authors investigated the association between intraoperative motor-evoked potential (MEP) changes and the severity of spinal cord infarction diagnosed with magnetic resonance imaging (MRI) to clarify the discrepancy between them, which was observed in patients with postoperative motor deficits after thora...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章,多中心研究

    doi:10.1053/j.jvca.2018.12.004

    authors: Hattori K,Yoshitani K,Kato S,Kawaguchi M,Kawamata M,Kakinohana M,Yamada Y,Yamakage M,Nishiwaki K,Izumi S,Yoshikawa Y,Mori Y,Hasegawa K,Onishi Y

    更新日期:2019-07-01 00:00:00

  • Effects of milrinone versus epinephrine on left ventricular relaxation after cardiopulmonary bypass following myocardial revascularization: assessment by color m-mode and tissue Doppler.

    abstract:OBJECTIVE:The purpose of this study was to evaluate the left ventricular lusitropic effects of epinephrine versus milrinone after cardiopulmonary bypass. DESIGN:Prospective randomized study. SETTING:Single institution, university teaching hospital. PARTICIPANTS:Adult patients undergoing coronary artery bypass grafti...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1053/j.jvca.2005.03.011

    authors: Lobato EB,Willert JL,Looke TD,Thomas J,Urdaneta F

    更新日期:2005-06-01 00:00:00

  • Effects of a novel benzodiazepine derivative, JM-1232(-), on human gastroepiploic artery in vitro.

    abstract:OBJECTIVE:To investigate the effects of JM-1232(-) on norepinephrine (10(-6) mol/L)- and high K(+) (40 mmol/L)-induced contractions in isolated human gastroepiploic arteries (GEA), and to compare them with the effects of midazolam and propofol. In addition, to investigate whether the benzodiazepine-receptor antagonist,...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2010.03.013

    authors: Moriyama T,Tsuneyoshi I,Kanmura Y

    更新日期:2011-02-01 00:00:00

  • Preoperative Implementation of Transverse Thoracic Muscle Plane Block and Rectus Sheath Block Combination for Pediatric Cardiac Surgery.

    abstract::Systemic intravenous administration of opioids is the main treatment strategy for intraoperative and postoperative pain management in patients undergoing cardiac surgery with sternotomy. However, using lower doses of opioids may achieve the well-established benefits of the fast-track approach, with minimal opioid-rela...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2020.07.041

    authors: Yamamoto T,Seino Y,Matsuda K,Imai H,Bamba K,Sugimoto A,Shiraishi S,Schindler E

    更新日期:2020-12-01 00:00:00

  • Markers of splanchnic perfusion and intestinal translocation of endotoxins during cardiopulmonary bypass: effects of dopamine and milrinone.

    abstract:OBJECTIVES:To investigate markers of splanchnic perfusion and the extent of endotoxemia during cardiopulmonary bypass (CPB) and to compare the effects of dopamine and milrinone on both splanchnic perfusion and endotoxemia. DESIGN:Prospective, randomized, blinded study. SETTING:University teaching hospital. PARTICIPA...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s1053-0770(99)90266-5

    authors: McNicol L,Andersen LW,Liu G,Doolan L,Baek L

    更新日期:1999-06-01 00:00:00

  • Anesthesia for Lung Transplantation in Cystic Fibrosis: Retrospective Review from the Irish National Transplantation Centre.

    abstract::Cystic fibrosis (CF) is an autosomal recessive disorder affecting approximately 1 in 2,500 live births worldwide, with double this estimated frequency in Ireland. CF is characterized by a genetic defect of the CF transmembrane regulator protein, causing impairment of chloride ion transportation. This has multisystem c...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2017.11.041

    authors: Lenihan M,Mullane D,Buggy D,Flood G,Griffin M

    更新日期:2018-10-01 00:00:00

  • Early continuous venovenous hemodialysis in dialysis-dependent patients after cardiac surgery: safety and efficacy.

    abstract:OBJECTIVES:The present study assessed the safety and efficacy of continuous venovenous hemodialysis (CVVHD) early after cardiac surgery. DESIGN:Retrospective database and medical record review. SETTING:University teaching hospital. PARTICIPANTS:Forty-five dialysis-dependent patients who underwent cardiac surgery wit...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2006.02.003

    authors: Nakasuji M,Nishi S,Nakasuji K,Hamaoka N,Ikeshita K,Asada A

    更新日期:2007-06-01 00:00:00

  • Cardiopulmonary bypass is associated with altered vascular reactivity of isolated pulmonary artery in a porcine model: therapeutic potential of inhaled tezosentan.

    abstract:OBJECTIVE:Whereas it is established that endothelin-1 elicits sustained deleterious effects on the cardiovascular system during cardiopulmonary bypass (CPB), presently it remains unknown whether the inhaled administration of the dual ETA and ETB antagonist tezosentan prevents the development of pulmonary endothelial dy...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1053/j.jvca.2013.12.013

    authors: Mommerot A,Denault AY,Dupuis J,Carrier M,Perrault LP

    更新日期:2014-06-01 00:00:00

  • Comparison of phenoxybenzamine to sodium nitroprusside in infants undergoing surgery.

    abstract:OBJECTIVES:The purpose of this study was to compare the effects of a direct-acting arterial dilator, sodium nitroprusside, to an alpha-adrenergic receptor blocker, phenoxybenzamine, in infants with congenital heart defects undergoing cardiac repairs on cardiopulmonary bypass. DESIGN:A prospective, multicenter, observa...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章,多中心研究

    doi:10.1053/j.jvca.2004.11.010

    authors: Motta P,Mossad E,Toscana D,Zestos M,Mee R

    更新日期:2005-02-01 00:00:00

  • Hydroxocobalamin Versus Methylene Blue for Vasoplegic Syndrome in Cardiothoracic Surgery: A Retrospective Cohort.

    abstract:OBJECTIVE:To compare methylene blue with hydroxocobalamin as a rescue therapy for vasoplegic syndrome. DESIGN:Retrospective cohort. SETTING:Academic medical center. PARTICIPANTS:Patients undergoing cardiothoracic surgery treated for vasoplegic syndrome. INTERVENTIONS:Thirty-five patients were treated with methylene...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2020.01.033

    authors: Furnish C,Mueller SW,Kiser TH,Dufficy L,Sullivan B,Beyer JT

    更新日期:2020-07-01 00:00:00

  • Activated Coagulation Time and Hepcon Protamine Titration Device to Manage Unfractionated Heparin During Cardiopulmonary Bypass in a Hemophilia A Patient on Emicizumab.

    abstract::In the perioperative management of patients with hemophilia A, emicizumab prevents the accurate measurement of common clotting assays, including the activated clotting time (ACT), which is essential for high-dose heparin monitoring during cardiopulmonary bypass surgery. The authors describe the successful perioperativ...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2020.08.058

    authors: Isaacs J,Welsby IJ,Schroder JN,Onwuemene OA

    更新日期:2020-08-27 00:00:00

  • Pharmacodynamics of pentamorphone during coronary artery bypass grafting in humans.

    abstract::Pentamorphone is a new, highly potent opioid reported to have minimal cardiovascular effects in humans and a high therapeutic index in animals. Pentamorphone was injected intravenously (IV) as the sole anesthetic in 10 patients with left ventricular ejection fractions greater than 0.35 who were undergoing elective cor...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1016/1053-0770(92)90192-a

    authors: Falinski BA,Sebel PS,Hug CC Jr,Klochany A

    更新日期:1992-04-01 00:00:00

  • Coagulation Derangements in Patients With Refractory Cardiac Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation.

    abstract:OBJECTIVE:Extracorporeal cardiopulmonary resuscitation (eCPR) with venoarterial extracorporeal membrane oxygenation (VA-ECMO) is gaining importance as a rescue therapy for refractory cardiac arrest. VA-ECMO, especially in the setting of eCPR, is plagued by hemorrhagic and thromboembolic complications. The authors' aims...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2018.11.014

    authors: Ruggeri L,Franco A,Alba AC,Lembo R,Frassoni S,Scandroglio AM,Calabrò MG,Zangrillo A,Pappalardo F

    更新日期:2019-07-01 00:00:00

  • Meta-analysis of randomized trials of effect of milrinone on mortality in cardiac surgery: an update.

    abstract:OBJECTIVE:The long-term use of milrinone is associated with increased mortality in chronic heart failure. A recent meta-analysis suggested that it might increase mortality in patients undergoing cardiac surgery. The authors conducted an updated meta-analysis of randomized trials in patients undergoing cardiac surgery t...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1053/j.jvca.2012.08.005

    authors: Majure DT,Greco T,Greco M,Ponschab M,Biondi-Zoccai G,Zangrillo A,Landoni G

    更新日期:2013-04-01 00:00:00

  • The level of cardiac output affects the relationship and agreement between pulmonary artery and transpulmonary aortic thermodilution measurements in an animal model.

    abstract:OBJECTIVE:The authors investigated the relationship between pulmonary artery and transpulmonary aortic thermodilution cardiac output measurements under conditions of increasing cardiac output (CO). DESIGN:Animal study with repeated simultaneous measurements comparing 2 cardiac output measurement techniques. SETTING:E...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2007.01.005

    authors: Hüter L,Schwarzkopf KR,Preussler NP,Schubert H,Schreiber T

    更新日期:2007-10-01 00:00:00

  • Tricuspid Regurgitation in Congestive Heart Failure: Management Strategies and Analysis of Outcomes.

    abstract::Tricuspid regurgitation is a notable aspect of congestive heart failure and is linked with worse outcomes if untreated. Functional tricuspid regurgitation commonly is seen in patients with heart failure, particularly in patients presenting for surgical management, such as those for mechanical cardiac assist device imp...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章,评审

    doi:10.1053/j.jvca.2020.06.022

    authors: Ramsdell GC,Nelson JA,Pislaru SV,Ramakrishna H

    更新日期:2020-06-12 00:00:00

  • Prediction of volume-responsiveness during one-lung ventilation: a comparison of static, volumetric, and dynamic parameters of cardiac preload.

    abstract:OBJECTIVES:The aim of this study was to evaluate the ability of static, volumetric, and dynamic parameters of cardiac preload to predict volume responsiveness during one-lung ventilation (OLV). DESIGN:Prospective experimental study. SETTING:Laboratory of the animal facility of the University Medical Center Hamburg-Ep...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/j.jvca.2013.05.003

    authors: Trepte CJ,Haas SA,Nitzschke R,Salzwedel C,Goetz AE,Reuter DA

    更新日期:2013-12-01 00:00:00

  • Change in plasma glutamate concentration during cardiac surgery is a poor predictor of cognitive outcome.

    abstract:OBJECTIVE:To develop a simple and reliable method for quantitating plasma glutamate concentration and apply this method to monitor systemic glutamate levels during coronary artery bypass graft (CABG) surgery, a procedure associated with neurologic deficits. DESIGN:Prospective serial investigation of cardiac surgery pa...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章

    doi:10.1053/jcan.2002.125148

    authors: Reynolds JD,Amory DW,Grocott HP,White WD,Newman MF

    更新日期:2002-08-01 00:00:00

  • Recent advances in chronic thromboembolic pulmonary hypertension.

    abstract::Surgical excellence in pulmonary thromboendarterectomy (PTE) for chronic thromboembolic pulmonary hypertension (CTEPH) has begun to spread around the world. The perioperative mortality for this procedure is typically under 10%. The maximal benefit from PTE is derived in those patients who have a high proximal clot bur...

    journal_title:Journal of cardiothoracic and vascular anesthesia

    pub_type: 杂志文章,评审

    doi:10.1053/j.jvca.2011.03.182

    authors: Stein E,Ramakrishna H,Augoustides JG

    更新日期:2011-08-01 00:00:00