Abstract:
:Monkeypox (MPX) is a zoonotic disease similar to smallpox. Its fatality rate is about 11% and it is endemic to the Central and West African countries. In this paper, we analyze a compartmental model of MPX dynamics. Our goal is to see whether MPX can be controlled and eradicated by voluntary vaccinations. We show that there are three equilibria-disease free, fully endemic and previously neglected semi-endemic (with disease existing only among humans). The existence of semi-endemic equilibrium has severe implications should the MPX virus mutate to increased viral fitness in humans. We find that MPX is controllable and can be eradicated in a semi-endemic equilibrium by vaccination. However, in a fully endemic equilibrium, MPX cannot be eradicated by vaccination alone.
journal_name
PeerJjournal_title
PeerJauthors
Bankuru SV,Kossol S,Hou W,Mahmoudi P,Rychtář J,Taylor Ddoi
10.7717/peerj.9272subject
Has Abstractpub_date
2020-06-22 00:00:00pages
e9272issn
2167-8359pii
9272journal_volume
8pub_type
杂志文章相关文献
PeerJ文献大全abstract:BACKGROUND:Because etomidate induces prolonged adrenal suppression, even following a single bolus, its use as an infused anesthetic is limited. Our previous study indicated that a single administration of the novel etomidate analog methoxyethyletomidate hydrochloride (ET-26-HCl) shows little suppression of adrenocortic...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3693
更新日期:2017-09-04 00:00:00
abstract::In agricultural landscape, there are thousands of young wild animals killed every year. Their deaths are caused mostly by agricultural fieldworks during spring harvest. Among the affected animals there are also fawns of roe deer (Capreolus capreolus), which react to danger by pressing themselves against the ground in ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6923
更新日期:2019-05-10 00:00:00
abstract:BACKGROUND:Periodization is an important component of resistance training programs. It is meant to improve adherence to the training regimen, allow for constant progression, help in avoiding plateaus, and reduce occurrence and severity of injuries. Previous findings regarding the effects of different periodization mode...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3695
更新日期:2017-08-22 00:00:00
abstract::Methionine (Met) is an essential sulfur-containing amino acid in animals. Cereal and legume crops with limiting levels of Met represent the major food and feed sources for animals. In plants, cystathionine gamma-synthase (CGS), methionine methyltransferase (MMT) and homocysteine methyltransferase (HMT) are committing ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6023
更新日期:2018-12-04 00:00:00
abstract::Four species of true crocodile (genus Crocodylus) have been described from the Americas. Three of these crocodile species exhibit non-overlapping distributions-Crocodylus intermedius in South America, C. moreletii along the Caribbean coast of Mesoamerica, and C. rhombifer confined to Cuba. The fourth, C. acutus, is na...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5836
更新日期:2018-11-12 00:00:00
abstract::Palythoa caribaeorum is a zoanthid often dominant in shallow rocky environments along the west coast of the Atlantic Ocean, from the tropics to the subtropics. This species has high environmental tolerance and is a good space competitor in reef environments. Considering current and future scenarios in the global clima...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.4777
更新日期:2018-05-17 00:00:00
abstract::At the turn of February and March 2020, COVID-19 pandemic reached Europe. Many countries, including Poland imposed lockdown as a method of securing social distance between potentially infected. Stay-at-home orders and movement control within public space not only affected the touristm industry, but also the everyday l...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.10132
更新日期:2020-10-05 00:00:00
abstract::For the past several centuries, millipede taxonomists have used the morphology of male copulatory structures (modified legs called gonopods), which are strongly variable and suggestive of species-level differences, as a source to understand taxon relationships. Millipedes in the family Xystodesmidae are blind, dispers...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3854
更新日期:2017-10-12 00:00:00
abstract:Purpose:This study aimed to examine differences between track and field (T&F) runners and foot-orienteers (Foot-O) in the walking and running tests in the absence of vision and hearing. We attempted to determine whether experienced foot orienteers show better ability to maintain the indicated direction compared to trac...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7736
更新日期:2019-09-26 00:00:00
abstract::A new genus with a new species of the tribe Hoplocampini of Hoplocampinae was described from China: Analcellicampa xanthosoma Wei & Niu, gen. et sp. nov.Hoplocampa danfengensis G. Xiao 1994 was designated as the type species of the new genus. The characters of Analcellicampa danfengensis (G. Xiao) comb. nov. were brie...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6866
更新日期:2019-05-02 00:00:00
abstract:BACKGROUND:Rare or narrowly endemic organisms are difficult to monitor and conserve when their total distribution and habitat preferences are incompletely known. One method employed in determining distributions of these organisms is species distribution modeling (SDM). METHODS:Using two species of narrowly endemic bur...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3632
更新日期:2017-07-31 00:00:00
abstract::Plasma membrane NADPH oxidases, also named respiratory burst oxidase homologues (Rbohs), play pivotal roles in many aspects of growth and development, as well as in responses to hormone signalings and various biotic and abiotic stresses. Although Rbohs family members have been identified in several plants, little is k...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8404
更新日期:2020-01-17 00:00:00
abstract::Melanoma is a global concern and accounts for the major mortality of skin cancers. Herpes simplex virus thymidine kinase gene with ganciclovir (HSV-TK/GCV) is a promising gene therapy for melanoma. Despite its low efficiency, it is well known for its bystander effect which is mainly mediated by gap junction. In this s...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7760
更新日期:2019-09-20 00:00:00
abstract::Natural products from the unique environments of sea water and oceans represent a largely unfamiliar source for isolation of new microbes, which are potent producers of secondary bioactive metabolites. These unique life-forms from the marine ecosphere have served as an important source of drugs since ancient times and...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5049
更新日期:2018-06-27 00:00:00
abstract::Many migratory bird species show high levels of site fidelity to their wintering sites, which confers advantages due to prior knowledge, but may also limit the ability of the individual to move away from degrading sites or to detect alternative foraging opportunities. Winter site fidelity often varies among age groups...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.2517
更新日期:2016-09-28 00:00:00
abstract::Understanding characteristics of torso motion and arm swing of older adults is important. A comprehensive database of three-dimensional thoracic and pelvic kinematics and arm swing maximum velocity of older adults during overground walking is still lacking. Moreover, the relationships between these variables are not f...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9329
更新日期:2020-07-07 00:00:00
abstract::Coral diseases are a leading factor contributing to the global decline of coral reefs, and yet mechanisms of disease transmission remain poorly understood. This study tested whether zooplankton can act as a vector for white band disease (WBD) in Acropora cervicornis. Natural zooplankton communities were collected from...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3502
更新日期:2017-07-07 00:00:00
abstract:Background:Several heart malformations are associated with mutations in the regulatory regions of cardiac genes. Troponin I type 1b (tnni1b) is important for the formation of the atrioventricular canal in zebrafish hearts; however, the regulation of tnni1b is poorly understand. We aimed to identify a small but function...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.10289
更新日期:2020-11-04 00:00:00
abstract:BACKGROUND:Individuals with unilateral lower limb amputation have a high risk of developing knee osteoarthritis (OA) in their intact limb as they age. This risk may be related to joint loading experienced earlier in life. We hypothesized that loading during walking would be greater in the intact limb of young US milita...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.2960
更新日期:2017-02-02 00:00:00
abstract::Heterodonty in Crocodylia and closely related taxa has not been defined quantitatively, as the teeth rarely have been measured. This has resulted in a range of qualitative descriptors, with little consensus on the condition of dental morphology in the clade. The purpose of this study is to present a method for the qua...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6485
更新日期:2019-02-28 00:00:00
abstract::Diarrhea is a syndrome of digestive disorders in young rabbits and may lead to secondary infections resulting in reduced immunity and higher mortality in baby rabbits, with serious impacts on rabbit farming. In this study, we investigated the effects of diarrhea on the health of baby rabbits in terms of intestinal muc...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.4100
更新日期:2017-11-27 00:00:00
abstract::Background. Low use of maternal healthcare services is one of the reasons why maternal mortality is still considerably high among adolescents mothers in India. To increase the utilization of these services, it is necessary to identify factors that affect service utilization. To our knowledge, no national level study i...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.592
更新日期:2014-11-04 00:00:00
abstract:BACKGROUND:Quercus infectoria G. Olivier (Fagaceae) nutgalls have been widely employed in traditional Asian medicine for several treatments, especially wounds and skin disorders. However, the effects of this plant on wound healing have not yet been clearly elucidated. This present work was focused on utilization of Que...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3608
更新日期:2017-07-24 00:00:00
abstract::We study the glycosylation processes that convert initially toxic substrates to nutritionally valuable metabolites in the flavonoid biosynthesis pathway of tomato (Solanum lycopersicum) seedlings. To estimate the reaction rates we use ordinary differential equations (ODEs) to model the enzyme kinetics. A popular choic...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.2417
更新日期:2016-09-20 00:00:00
abstract::The exploration of the evolution of RNA viruses has been aided recently by the discovery of copies of fragments or complete genomes of non-retroviral RNA viruses (Non-retroviral Endogenous RNA Viral Elements, or NERVEs) in many eukaryotic nuclear genomes. Among the most prominent NERVEs are partial copies of the RNA d...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.876
更新日期:2015-04-09 00:00:00
abstract::The role of glial cells in pain modulation has recently gathered attention. The objective of this study was to determine healthy spinal microglia and astrocyte morphology and disposition in equine spinal cord dorsal horns using Iba-1 and GFAP/Cx-43 immunofluorescence labeling, respectively. Five adult horses without v...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3965
更新日期:2017-10-27 00:00:00
abstract::A phylogenetic taxonomy of species in the Cyrtodactylus peguensis group from the Ayeyarwady Basin of Myanmar is constructed based on color pattern, morphology, and molecular systematic analyses using the mitochondrial gene NADH dehydrogenase subunit 2. Newly collected samples from the type locality of C. peguensis and...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5575
更新日期:2018-09-19 00:00:00
abstract::We revise the taxonomy of the myrmicine ants of the Monomorium monomorium species-group for the Arabian Peninsula. Six species are recognized: Monomorium aeyade Collingwood & Agosti, 1996, M. clavicorne André, 1881, M. exiguum Forel, 1894, M. holothir Bolton, 1987, M. mohammedi sp. n., and M. sarawatense Sharaf & Alda...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.4277
更新日期:2018-02-01 00:00:00
abstract::Soil sickness is the progressive loss of soil quality due to continuous monocropping. The bacterial populations are critical to sustaining agroecosystems, but their responses to long-term peanut monocropping have not been determined. In this study, based on a previously constructed gradient of continuous monocropped p...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.9024
更新日期:2020-04-28 00:00:00
abstract::Introduction. Adolescent interpersonal violence is a global public health problem, yet gaps remain in the epidemiologic literature on adolescent violence in low- and middle-income countries (LMIC). Prevalence rates and risk and protective factors reported in high-income countries may be different from those reported i...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.125
更新日期:2013-08-13 00:00:00