Potential wound healing activity of Quercus infectoria formulation in diabetic rats.

Abstract:

BACKGROUND:Quercus infectoria G. Olivier (Fagaceae) nutgalls have been widely employed in traditional Asian medicine for several treatments, especially wounds and skin disorders. However, the effects of this plant on wound healing have not yet been clearly elucidated. This present work was focused on utilization of Quercus infectoria (Qi) as a topical agent for chronic wound treatment. METHODS:Twenty Qi formulations (QiFs) were pharmaceutically formulated and antibacterial activity of all formulations was performed. The best formulation based on an antibacterial activity was selected for evaluation of wound healing property. Total phenolics, total flavonoids, and an anti-oxidant activity of the selected formulation were also investigated. Wound healing activity was assessed in streptozotocin-induced diabetic rats and control rats. Streptozotocin injection (50 mg/kg) was found to induce marked hyperglycaemia, compared with citrate-injected controls. Two wounds were created on the upper back of each animal. QiF was topically applied three days after wounding to one of the duplicate wounds on each animal and physiological saline (control) was applied to the other. All wounds were cleaned once a day until wound closure. RESULTS:QiF10, which exhibited antibacterial and anti-oxidant activities, had the ability to enhance the wound healing process in diabetic rats with abundant cellular infiltration, collagen deposition, and re-epithelialization when compared with the control. DISCUSSION:This study suggested that QiF10 could be a novel alternative treatment for diabetic wounds.

journal_name

PeerJ

journal_title

PeerJ

authors

Chokpaisarn J,Chusri S,Amnuaikit T,Udomuksorn W,Voravuthikunchai SP

doi

10.7717/peerj.3608

subject

Has Abstract

pub_date

2017-07-24 00:00:00

pages

e3608

issn

2167-8359

pii

3608

journal_volume

5

pub_type

杂志文章

相关文献

PeerJ文献大全
  • A unified simulation model for understanding the diversity of cancer evolution.

    abstract::Because cancer evolution underlies the therapeutic difficulties of cancer, it is clinically important to understand the evolutionary dynamics of cancer. Thus far, a number of evolutionary processes have been proposed to be working in cancer evolution. However, there exists no simulation model that can describe the dif...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.8842

    authors: Niida A,Hasegawa T,Innan H,Shibata T,Mimori K,Miyano S

    更新日期:2020-04-08 00:00:00

  • A detailed observation of the ejection and retraction of defense tissue acontia in sea anemone (Exaiptasia pallida).

    abstract::Acontia, located in the gastrovascular cavity of anemone, are thread-like tissue containing numerous stinging cells which serve as a unique defense tissue against predators of the immobile acontiarian sea anemone. Although its morphology and biological functions, such as defense and digestion, have been studied, the d...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2996

    authors: Lam J,Cheng YW,Chen WU,Li HH,Chen CS,Peng SE

    更新日期:2017-02-21 00:00:00

  • Immunofluorescence characterization of spinal cord dorsal horn microglia and astrocytes in horses.

    abstract::The role of glial cells in pain modulation has recently gathered attention. The objective of this study was to determine healthy spinal microglia and astrocyte morphology and disposition in equine spinal cord dorsal horns using Iba-1 and GFAP/Cx-43 immunofluorescence labeling, respectively. Five adult horses without v...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3965

    authors: Meneses CS,Müller HY,Herzberg DE,Uberti B,Bustamante HA,Werner MP

    更新日期:2017-10-27 00:00:00

  • Element concentrations in pelagic Sargassum along the Mexican Caribbean coast in 2018-2019.

    abstract::The massive influx of pelagic Sargassum spp. (sargasso) into the Mexican Caribbean Sea has caused major deterioration of the coastal environment and has affected the tourism industry as well as livelihoods since 2015. Species of Sargassum have high capacity to absorb metals; thus, leachates of sargasso may contribute ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.8667

    authors: Rodríguez-Martínez RE,Roy PD,Torrescano-Valle N,Cabanillas-Terán N,Carrillo-Domínguez S,Collado-Vides L,García-Sánchez M,van Tussenbroek BI

    更新日期:2020-02-26 00:00:00

  • An enigmatic decoupling between heat stress and coral bleaching on the Great Barrier Reef.

    abstract::Ocean warming threatens the functioning of coral reef ecosystems by inducing mass coral bleaching and mortality events. The link between temperature and coral bleaching is now well-established based on observations that mass bleaching events usually occur when seawater temperatures are anomalously high. However, times...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.7473

    authors: DeCarlo TM,Harrison HB

    更新日期:2019-08-12 00:00:00

  • Identification of priority shorebird conservation areas in the Caribbean.

    abstract::Despite being geographically central to the Atlantic Americas Flyway for migratory birds, the Caribbean is often overlooked or underappreciated when addressing the conservation of North American shorebirds. To our knowledge, this is the first Caribbean-wide assessment of shorebird use in the region. We analyzed 211,01...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.9831

    authors: Cañizares JR,Reed JM

    更新日期:2020-09-08 00:00:00

  • Are invasive populations characterized by a broader diet than native populations?

    abstract:BACKGROUND:Invasive species are among the most significant threats to biodiversity. The diet of invasive animal populations is a crucial factor that must be considered in the context of biological invasions. A broad dietary spectrum is a frequently cited characteristic of invasive species, allowing them to thrive in a ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3250

    authors: Courant J,Vogt S,Marques R,Measey J,Secondi J,Rebelo R,De Villiers A,Ihlow F,De Busschere C,Backeljau T,Rödder D,Herrel A

    更新日期:2017-05-16 00:00:00

  • Trends and topics in eye disease research in PubMed from 2010 to 2014.

    abstract:BACKGROUND:The purpose of this study is to provide a report on scientific production during the period 2010-2014 in order to identify the major topics as well as the predominant actors (journals, countries, continents) involved in the field of eye disease. METHODS:A PubMed search was carried out to extract articles re...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.1557

    authors: Boudry C,Denion E,Mortemousque B,Mouriaux F

    更新日期:2016-01-07 00:00:00

  • Stress profile influences learning approach in a marine fish.

    abstract::The spatial learning skills of high and low stress juvenile mulloway (Argyrosomus japonicus) were tested in a dichotomous choice apparatus. Groups of fish were formed based on background blood cortisol levels and required to learn the location of a food reward hidden in one of two compartments. Low stress fish charact...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3445

    authors: Raoult V,Trompf L,Williamson JE,Brown C

    更新日期:2017-06-08 00:00:00

  • Avian community structure and habitat use of Polylepis forests along an elevation gradient.

    abstract:BACKGROUND:As one of the highest forest ecosystems in the world, Polylepis forests are recognized both as center of endemism and diversity along the Andes and as an ecosystem under serious threat from habitat loss, fragmentation, and climate change due to human activities. Effective conservation efforts are limited, in...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3220

    authors: Sevillano-Ríos CS,Rodewald AD

    更新日期:2017-04-27 00:00:00

  • Evaluation of granular anaerobic ammonium oxidation process for the disposal of pre-treated swine manure.

    abstract::With rising environmental concerns on potable water safety and eutrophication, increased media attention and tighter environmental regulations, managing animal waste in an environmentally responsible and economically feasible way can be a challenge. In this study, the possibility of using granular anammox process for ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.336

    authors: Ni SQ,Yang N

    更新日期:2014-04-08 00:00:00

  • Necessity of electrically conductive pili for methanogenesis with magnetite stimulation.

    abstract:Background:Magnetite-mediated direct interspecies electron transfer (DIET) between Geobacter and Methanosarcina species is increasingly being invoked to explain magnetite stimulation of methane production in anaerobic soils and sediments. Although magnetite-mediated DIET has been documented in defined co-cultures reduc...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.4541

    authors: Wang O,Zheng S,Wang B,Wang W,Liu F

    更新日期:2018-03-21 00:00:00

  • The R2R3-MYB transcription factor family in Taxus chinensis: identification, characterization, expression profiling and posttranscriptional regulation analysis.

    abstract::The MYB transcription factor family is one of the largest gene families playing regulatory roles in plant growth and development. The MYB family has been studied in a variety of plant species but has not been reported in Taxus chinensis. Here we identified 72 putative R2R3-MYB genes in T. chinensis using a comprehensi...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.8473

    authors: Hu X,Zhang L,Wilson I,Shao F,Qiu D

    更新日期:2020-02-17 00:00:00

  • Multiphasic strain differentiation of atypical mycobacteria from elephant trunk wash.

    abstract::Background. Two non-tuberculous mycobacterial strains, UM_3 and UM_11, were isolated from the trunk wash of captive elephants in Malaysia. As they appeared to be identical phenotypes, they were investigated further by conventional and whole genome sequence-based methods of strain differentiation. Methods. Multiphasic ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.1367

    authors: Chan KG,Loke MF,Ong BL,Wong YL,Hong KW,Tan KH,Kaur S,Ng HF,Abdul Razak M,Ngeow YF

    更新日期:2015-11-10 00:00:00

  • Correction: Prevalence and correlates of psychological distress among diabetes mellitus adults in the Jilin province in China: a cross-sectional study.

    abstract::[This corrects the article DOI: 10.7717/peerj.2869.]. ...

    journal_title:PeerJ

    pub_type: 杂志文章,已发布勘误

    doi:10.7717/peerj.2869/correction-1

    authors: Qiu S,Sun H,Liu Y,Kanu JS,Li R,Yu Y,Huang X,Li B,Zhang X

    更新日期:2017-12-07 00:00:00

  • Blood serum and BSA, but neither red blood cells nor hemoglobin can support vitellogenesis and egg production in the dengue vector Aedes aegypti.

    abstract::Aedes aegypti is the major vector of dengue, yellow fever and chikungunya viruses that put millions of people in endemic countries at risk. Mass rearing of this mosquito is crucial for strategies that use modified insects to reduce vector populations and transmission of pathogens, such as sterile insect technique or p...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.938

    authors: Gonzales KK,Tsujimoto H,Hansen IA

    更新日期:2015-05-05 00:00:00

  • A predictive model for canine dilated cardiomyopathy-a meta-analysis of Doberman Pinscher data.

    abstract::Dilated cardiomyopathy is a prevalent and often fatal disease in humans and dogs. Indeed dilated cardiomyopathy is the third most common form of cardiac disease in humans, reported to affect approximately 36 individuals per 100,000 individuals. In dogs, dilated cardiomyopathy is the second most common cardiac disease ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.842

    authors: Simpson S,Edwards J,Emes RD,Cobb MA,Mongan NP,Rutland CS

    更新日期:2015-03-26 00:00:00

  • BCD Beam Search: considering suboptimal partial solutions in Bad Clade Deletion supertrees.

    abstract::Supertree methods enable the reconstruction of large phylogenies. The supertree problem can be formalized in different ways in order to cope with contradictory information in the input. Some supertree methods are based on encoding the input trees in a matrix; other methods try to find minimum cuts in some graph. Recen...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.4987

    authors: Fleischauer M,Böcker S

    更新日期:2018-06-08 00:00:00

  • Self-centeredness and selflessness: happiness correlates and mediating psychological processes.

    abstract::The main objective of this research was to test central assumptions from the Self-centeredness/Selflessness Happiness Model. According to this model, while self-centered psychological functioning induces fluctuating happiness, authentic-durable happiness results from selflessness. Distinct mediating processes are supp...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3306

    authors: Dambrun M

    更新日期:2017-05-11 00:00:00

  • The nine ADAMs family members serve as potential biomarkers for immune infiltration in pancreatic adenocarcinoma.

    abstract:Background:The functional significance of ADAMs family members in the immune infiltration of pancreatic adenocarcinoma (PAAD) awaits elucidation. Methods:ADAMs family members with significant expression were identified among differentially expressed genes of PAAD based on The Cancer Genome Atlas (TCGA) database follow...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.9736

    authors: Qi B,Liu H,Dong Y,Shi X,Zhou Q,Zeng F,Bao N,Li Q,Yuan Y,Yao L,Xia S

    更新日期:2020-09-30 00:00:00

  • Impact of exposure to tobacco smoke, arsenic, and phthalates on locally advanced cervical cancer treatment-preliminary results.

    abstract:BACKGROUND:Cancer research is a national and international priority, with the efficiency and effectiveness of current anti-tumor therapies being one of the major challenges with which physicians are faced. OBJECTIVE:To assess the impact of exposure to tobacco smoke, arsenic, and phthalates on cervical cancer treatment...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2448

    authors: Neamtiu IA,Bloom MS,Dumitrascu I,Roba CA,Pop C,Ordeanu C,Balacescu O,Gurzau ES

    更新日期:2016-09-08 00:00:00

  • Correction: Neither slim nor fat: estimating the mass of the dodo (Raphus cucullatus, Aves, Columbiformes) based on the largest sample of dodo bones to date.

    abstract::[This corrects the article DOI: 10.7717/peerj.4110.]. ...

    journal_title:PeerJ

    pub_type: 杂志文章,已发布勘误

    doi:10.7717/peerj.4110/correction-1

    authors: van Heteren AH,van Dierendonck RCH,van Egmond MANE,Ten Hagen SL,Kreuning J

    更新日期:2017-12-20 00:00:00

  • Hardly habitual: chimpanzees and gorillas show flexibility in their motor responses when presented with a causally-clear task.

    abstract::In contrast to reports of wild primates, studies of captive primates' flexibility often reveal conservatism: individuals are unable to switch to new and more efficient strategies when task demands change. We propose that such conservatism might be a result of task design and hypothesize that conservatism might be link...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.6195

    authors: Jacobson SL,Hopper LM

    更新日期:2019-01-08 00:00:00

  • The influence of scopolamine on motor control and attentional processes.

    abstract:BACKGROUND:Motion sickness may be caused by a sensory conflict between the visual and the vestibular systems. Scopolamine, known to be the most effective therapy to control the vegetative symptoms of motion sickness, acts on the vestibular nucleus and potentially the vestibulospinal pathway, which may affect balance an...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2008

    authors: Bestaven E,Kambrun C,Guehl D,Cazalets JR,Guillaud E

    更新日期:2016-05-05 00:00:00

  • Skin bacterial communities of neotropical treefrogs vary with local environmental conditions at the time of sampling.

    abstract::The amphibian skin microbiome has been the focus of recent studies aiming to better understand the role of these microbial symbionts in host defense against disease. However, host-associated microbial communities are complex and dynamic, and changes in their composition and structure can influence their function. Unde...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.7044

    authors: Estrada A,Hughey MC,Medina D,Rebollar EA,Walke JB,Harris RN,Belden LK

    更新日期:2019-06-21 00:00:00

  • Water environmental stress, rebound effect, and economic growth of China's textile industry.

    abstract::The rapid development of China's textile industry (TI) has led to severe water environmental stress. Water environmental stress of China's TI mainly comes from large quantities of discharged wastewater and chemical oxygen demand (COD). The sustainable development of the TI is realized to achieve the decoupling between...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.5112

    authors: Li Y,Shen J,Lu L,Luo Y,Wang L,Shen M

    更新日期:2018-06-29 00:00:00

  • Differences in the support needs of children with developmental disabilities among groups of medical and behavioral needs.

    abstract:Background/Aims:Medical and behavioral needs are relevant in organizing and providing support strategies that improve the quality of life for children, along with their families. The present study aims to examine the impact of medical and behavioral needs on the need for support of children with disabilities. Methods:...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.9557

    authors: Arias VB,Aguayo V,Verdugo MA,Amor AM

    更新日期:2020-09-15 00:00:00

  • Proceraea exoryxae sp. nov. (Annelida, Syllidae, Autolytinae), the first known polychaete miner tunneling into the tunic of an ascidian.

    abstract::While studying organisms living in association with the solitary tunicate Phallusia nigra (Ascidiacea, Ascidiidae) from a shallow fringing reef at Zeytouna Beach (Egyptian Red Sea), one of the collected ascidians showed peculiar perforations on its tunic. Once dissected, the perforations revealed to be the openings of...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3374

    authors: Martin D,Nygren A,Cruz-Rivera E

    更新日期:2017-06-01 00:00:00

  • A computational method for the systematic screening of reaction barriers in enzymes: searching for Bacillus circulans xylanase mutants with greater activity towards a synthetic substrate.

    abstract::We present a semi-empirical (PM6-based) computational method for systematically estimating the effect of all possible single mutants, within a certain radius of the active site, on the barrier height of an enzymatic reaction. The intent of this method is not a quantitative prediction of the barrier heights, but rather...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.111

    authors: Hediger MR,Steinmann C,De Vico L,Jensen JH

    更新日期:2013-07-23 00:00:00

  • DeepSNVMiner: a sequence analysis tool to detect emergent, rare mutations in subsets of cell populations.

    abstract::Background. Massively parallel sequencing technology is being used to sequence highly diverse populations of DNA such as that derived from heterogeneous cell mixtures containing both wild-type and disease-related states. At the core of such molecule tagging techniques is the tagging and identification of sequence read...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2074

    authors: Andrews TD,Jeelall Y,Talaulikar D,Goodnow CC,Field MA

    更新日期:2016-05-24 00:00:00