Abstract:
BACKGROUND:Hyperparathyroidism (HPT) is characterised by increased levels of parathyroid hormone (HPT), surgical excision being the only definitive curative option. After establishing the need for surgery, it is essential to identify the parathyroid glands in the preoperative period to use a minimally invasive approach. Negativity and / or discrepancy in first-line studies (ultrasound and Tc-99m MIBI parathyroid scintigraphy) require more accurate images to reduce the likelihood of bilateral cervical exploration or reintervention. OBJECTIVES:a) To demonstrate the sensitivity of 18F-fluorocholine (18F-choline) positron emission tomography (PET)/4D computed tomography (4D CT) in HPT. b) To check whether there is a correlation between calcaemia and preoperative PTH versus size and early and late SUVmax (Standardized Uptake Value) of the gland, determined by 18F-choline PET/4D CT and c) to study the behaviour of parathyroid lesions with intravenous contrast (IV). MATERIAL AND METHODS:A total of 28 patients were included between 2016 and 2019 in a single institution. Prospective observational cohort study. Correlations were analysed using Pearson's coefficient for variables with normal distribution and Spearman (rho) for those with non-normal distribution. Anatomopathological analysis was the benchmark standard to determine sensitivity was. A p<.05 was interpreted as significant. STATA 13 software was used. RESULTS:Of the 28 patients who underwent 18F-choline PET/4D CT, 18 were operated. Of the 26 lesions diagnosed by 18F-choline PET/4D CT as suggestive of parathyroid lesions, 23 corresponded to glandular disease (adenoma or hyperplasia) establishing a sensitivity of 88.5%. There was a correlation between the patient's preoperative PTH and the maximum size of the gland on 18F-choline PET/4D CT. (Spearman=.66; p=.0014). The parathyroid lesions showed, in addition to IV contrast enhancement, distinctive behavioural characteristics identified as highly suggestive. CONCLUSIONS:18F-choline PET/CT 4D is an anatomical and functional study with high sensitivity in patients with HPT with negative or discrepant first-line studies. Preoperative PTH showed a correlation with maximum gland size on 18F-choline PET/CT 4D. Parathyroid lesions behave in a highly suggestive way and are enhanced by IV contrast.
journal_name
Rev Esp Med Nucl Imagen Moljournal_title
Revista espanola de medicina nuclear e imagen molecularauthors
Boccalatte LA,Gómez NL,Musumeci M,Galich AM,Collaud C,Figari MFdoi
10.1016/j.remn.2020.03.017subject
Has Abstractpub_date
2020-01-01 00:00:00pages
273-278issue
5eissn
2253-654Xissn
2253-8070pii
S2253-654X(20)30064-0journal_volume
39pub_type
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2012.08.003
更新日期:2013-01-01 00:00:00
abstract::Neurolymphomatosis is a rare condition defined as an infiltration of nerves, nerve roots or nervous plexuses by haematological malignancy. Its diagnosis may sometimes be difficult with conventional imaging techniques. This paper aims to emphasize the importance of this entity and the role of (18)F-FDG PET/CT in this i...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2013.03.004
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2019.01.002
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abstract:INTRODUCTION:Indocyanine green (ICG)-(99m)Tc-nanocolloid is a novel hybrid fluorescent radioactive tracer for sentinel node (SN) biopsy. This study has aimed to evaluate the added value of this novel versatile tracer in a series of patients with different malignancies. MATERIAL AND METHODS:Twenty patients (with penile...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
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abstract:OBJECTIVE:A major controversial issue in the sentinel node biopsy of the breast is the applicability of sentinel node mapping in patients with the history of previous excisional biopsy of the breast lesions. In the current study, we evaluated the reproducibility of lymphoscintigraphy before and after excisional biopsy ...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2012.07.004
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2015.07.005
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abstract::Moyamoya disease (MMD) is a cerebrovascular disorder involving stenosis of brain vessels. Brain perfusion SPECT in MMD demonstrates impaired perfusion in ischemic areas. We present a 6-year-old boy with MMD. The patient had numbness on the right arm and simultaneous electroencephalography changes while studying arms u...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2012.02.006
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journal_title:Revista espanola de medicina nuclear e imagen molecular
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journal_title:Revista espanola de medicina nuclear e imagen molecular
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2013.02.009
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 临床试验,杂志文章,多中心研究
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2016.05.005
更新日期:2017-01-01 00:00:00
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2016.09.002
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2013.04.006
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2012.01.004
更新日期:2013-01-01 00:00:00
abstract::A 49 year-old woman diagnosed with infiltrating lobular breast carcinoma, underwent a right mastectomy and sentinel node biopsy (SLNB). The resected sentinel lymph nodes were negative for malignancy, with an axillary lymphadenectomy not being performed. In the early post-operative period, the patient reported an axill...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2016.04.008
更新日期:2016-09-01 00:00:00
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2017.10.007
更新日期:2018-01-01 00:00:00
abstract::(99m)Tc-tetrofosmin single photon emission computed tomography ((99m)Tc-tetrofosmin SPECT) has an important role in the assessment of coronary artery disease. Despite being its main indication, this study does not only evaluate myocardial perfusion, but much more. Moreover, during the SPECT acquisition, the field area...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2015.03.005
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:The central nervous system (CNS) may be involved in a variety of inflammatory diseases of the blood vessels, generally known as vasculitis. The clinical diagnosis of such involvement in early stages is difficult, since a mild cognitive impairment can be the only symptom. It was hypothesized that brain-perfusi...
journal_title:Revista espanola de medicina nuclear e imagen molecular
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更新日期:2018-01-01 00:00:00
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2012.07.001
更新日期:2013-01-01 00:00:00
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journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
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abstract:OBJECTIVES:In 2009-2010 a Portuguese consortium was created to implement the methodologies proposed by the Dose Datamed II (DDM2) project, aiming to collect data from diagnostic X-ray and nuclear medicine (NM) procedures, in order to determine the most frequently prescribed exams and the associated ionizing radiation d...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2014.03.009
更新日期:2015-01-01 00:00:00
abstract::Multiple osteochondromatosis can become malignant in 20% of the cases, this being more common when the lesion is multiple than when it is solitary. A male patient with multiple osteochondromatosis who had several local recurrences of secondary chondrosarcoma and who is still under follow-up by the Nuclear Medicine Dep...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
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更新日期:2012-09-01 00:00:00
abstract::This publication presents criteria and bases for the work organization in the safe practice of Hospital Radiopharmacy, in order to minimize the risk of viral transmission during the COVID-19 pandemic, in a reference facility of the National Energy Commission Atomic of Argentina, while continuing to perform essential s...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2020.08.015
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:The goal was to evaluate the sentinel node procedure in relation to different pathways of lymphatic drainage and the areas of pelvic lymphadenectomy in patients with prostate cancer assessed by lymphoscintigraphy and SPECT/CT study. METHODS:Eighteen patients with prostate cancer of intermediate prognosis were ...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 临床试验,杂志文章
doi:10.1016/j.remn.2011.09.003
更新日期:2012-03-01 00:00:00