Abstract:
OBJECTIVES:Survival heterogeneity exists among patients with non-small cell lung cancer (NSCLC), even within the same stage. We aimed to evaluate the prognostic role of pre-treatment maximum standardized uptake value (SUVmax) in patients treated with definitive concurrent chemoradiotherapy for stage III NSCLC. MATERIALS AND METHODS:Between 2010 and 2017, 103 patients with stage III NSCLC who underwent 18F-FDG PET/CT at the time of diagnosis were included in the study. RESULTS:Higher tumor stages were correlated with higher pre-treatment SUVmax of lymph nodes (LNs) (p=0.005) but were not correlated with higher SUVmax of primary tumor (p=0.2). The median SUVmax of LNs was 2.84, 8.06, and 11.11 in stage IIIa, IIIb and IIIc, respectively. Higher nodal stage was also correlated with higher SUVmax of LNs (p=0.01). According to ROC analysis, there was no significant cut-off value of SUVmax observed for primary tumor, therefore continuous variables were used for survival analyses. The best SUVmax cut-off was 3.5 for the LNs, therefore the SUVmax of LNs was evaluated as both a dichotomous and a continuous variable. Pre-treatment SUVmax of primary tumor did not predict survival outcomes but both the continuous and dichotomous variables of SUVmax of LNs predicted recurrence free survival and overall survival. Nodal stage (N0-2 vs. N3) and AJCC stage (IIIa vs IIIb vs. IIIc) were the other prognostic factors. CONCLUSIONS:Pre-treatment SUVmax of LNs had prognostic value in patients treated with definitive concurrent chemoradiotherapy for stage III NSCLC. In future trials, pre-treatment SUVmax of the LNs would serve as a guide for patients who might benefit from more aggressive treatments.
journal_name
Rev Esp Med Nucl Imagen Moljournal_title
Revista espanola de medicina nuclear e imagen molecularauthors
Kanyilmaz G,Benli Yavuz B,Aktan M,Sahin Odoi
10.1016/j.remn.2019.04.006subject
Has Abstractpub_date
2020-01-01 00:00:00pages
20-26issue
1eissn
2253-654Xissn
2253-8070pii
S2253-654X(19)30059-9journal_volume
39pub_type
杂志文章abstract:OBJECTIVE:To assess the outcome after 131I treatment in patients with multinodular (MNG) and nodular toxic goitre (NTG) according to the administered dose and other factors related to the patient, pathology, or previous treatments. MATERIAL AND METHODS:A retrospective study was conducted on 108 patients (67 MNG and 41...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2017.03.010
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Hyperparathyroidism (HPT) is characterised by increased levels of parathyroid hormone (HPT), surgical excision being the only definitive curative option. After establishing the need for surgery, it is essential to identify the parathyroid glands in the preoperative period to use a minimally invasive approach...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2020.03.017
更新日期:2020-01-01 00:00:00
abstract::Neurolymphomatosis is a rare condition defined as an infiltration of nerves, nerve roots or nervous plexuses by haematological malignancy. Its diagnosis may sometimes be difficult with conventional imaging techniques. This paper aims to emphasize the importance of this entity and the role of (18)F-FDG PET/CT in this i...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2013.03.004
更新日期:2014-01-01 00:00:00
abstract::Chronic diarrhoea due to bile acid malabsorption (BAM) is an underdiagnosed pathology. Different diagnostic tools are available. However, there is currently no consensus on which of these would be the benchmark test or gold standard. This review evaluates the possibility of using 75Se-taurocholic acid (75SeHCAT®) scin...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章,评审
doi:10.1016/j.remn.2018.12.005
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:The goal was to evaluate the sentinel node procedure in relation to different pathways of lymphatic drainage and the areas of pelvic lymphadenectomy in patients with prostate cancer assessed by lymphoscintigraphy and SPECT/CT study. METHODS:Eighteen patients with prostate cancer of intermediate prognosis were ...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 临床试验,杂志文章
doi:10.1016/j.remn.2011.09.003
更新日期:2012-03-01 00:00:00
abstract::This publication presents criteria and bases for the work organization in the safe practice of Hospital Radiopharmacy, in order to minimize the risk of viral transmission during the COVID-19 pandemic, in a reference facility of the National Energy Commission Atomic of Argentina, while continuing to perform essential s...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2020.08.015
更新日期:2020-01-01 00:00:00
abstract::Prostate tumors originate 68% in the peripheral region and 24% in the transitional region where tumors originating in the central zone are rare (8%). However, diagnosis of the tumors in the central zone is important since they exhibit greater aggressiveness conditioned by their location and different biological behavi...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2013.07.013
更新日期:2014-03-01 00:00:00
abstract::About one third of focal thyroid uptakes in a fluorodeoxyglucose (FDG) positron emission tomography/computerized tomography (PET/CT) study are malignant, the most frequent histological type being papillary carcinoma. Metastases to the thyroid account for approximately 7.5% of thyroid malignancies and come mainly from ...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2016.09.002
更新日期:2017-01-01 00:00:00
abstract::A 49 year-old woman diagnosed with infiltrating lobular breast carcinoma, underwent a right mastectomy and sentinel node biopsy (SLNB). The resected sentinel lymph nodes were negative for malignancy, with an axillary lymphadenectomy not being performed. In the early post-operative period, the patient reported an axill...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2016.04.008
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To characterize the performance of the Biograph mCT PET/CT TrueV scanner with time of flight (TOF) and point spread function (PSF) modeling. MATERIAL AND METHODS:The PET/CT scanner combines a 64-slice CT and PET scanner that incorporates in the reconstruction the TOF and PSF information. PET operating charac...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2012.07.001
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Scintigraphy with iodine-123-metaiodobenzylguanidine ((123)I-MIBG) is a non-invasive tool for the assessment of cardiac sympathetic innervation (CSI) that has proven to be an independent predictor of survival. Recent studies have shown that diabetic patients with heart failure (HF) have a higher deterioratio...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2015.08.002
更新日期:2016-03-01 00:00:00
abstract::A 54-year-old man with progressive prostate cancer underwent a 68Ga-PSMA PET/CT, which showed lymph node and bone metastases. After 2-cycles of 177Lu-PSMA therapy, the repeated 68Ga-PSMA PET/CT showed decreased radiotracer uptake in lymph node and bones metastases, but there were new lesions which may be compatible wi...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2017.05.004
更新日期:2018-01-01 00:00:00
abstract::Leiomyomas are benign tumors derived from smooth muscle tissue that rarely present outside the uterus. These tumors do not usually show FDG uptake. We present the case of a patient with hypertension refractory to treatment and a lesion arising from inferior vena cava, that shows intense FDG uptake in PET/CT scan, sugg...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2019.06.006
更新日期:2020-01-01 00:00:00
abstract::Spontaneous intracranial hypotension is a clinical syndrome caused by a loss of cerebrospinal fluid volume, usually secondary to leaking through structural defects of the spinal dura mater. Radioisotope cisternography (RC) can confirm the diagnosis of spontaneous intracranial hypotension, especially in doubtful or aty...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2016.05.005
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To describe the process of implementing a quality management system according to UNE-EN-ISO 9001:2008 standard in a Nuclear Medicine Department. MATERIAL AND METHOD:In February 2008, the committee on internal quality of the Department was established, naming a responsible physician. The general operating pla...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2012.01.004
更新日期:2013-01-01 00:00:00
abstract::Multiple osteochondromatosis can become malignant in 20% of the cases, this being more common when the lesion is multiple than when it is solitary. A male patient with multiple osteochondromatosis who had several local recurrences of secondary chondrosarcoma and who is still under follow-up by the Nuclear Medicine Dep...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2011.10.011
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:To assess the diagnostic capability of PET/CT with [18F]F-Fluoromethylcholine in prostate cancer (PC) with biochemical recurrence and its therapeutic impact. MATERIAL AND METHODS:We included 108 patients, diagnosed with PC with biochemical criteria for recurrence. A PET/CT Choline scan was performed by dynam...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2020.03.010
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:A major controversial issue in the sentinel node biopsy of the breast is the applicability of sentinel node mapping in patients with the history of previous excisional biopsy of the breast lesions. In the current study, we evaluated the reproducibility of lymphoscintigraphy before and after excisional biopsy ...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2012.07.004
更新日期:2013-05-01 00:00:00
abstract::Functional neuroimaging with positron emission tomography with 18F-fluorodeoxyglucose (PET-18F-FDG) and perfusion single photon emission computerized tomography (SPECT) are increasingly more essential for presurgically locating the epileptogenic focus. We present the case of an 18-year-old male with epileptic seizures...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2019.01.002
更新日期:2019-01-01 00:00:00
abstract:AIM:To assess the calcification process of the carotid plaque by (18)F-sodium fluoride PET/CT imaging. MATERIAL AND METHODS:A prospectively designed study including 15 patients in whom an atheroma plaque was detected by contrast enhanced CT scan during a neurological work-up was performed. A total of 29 plaques, 19 as...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2012.08.003
更新日期:2013-01-01 00:00:00
abstract::Hydronephrosis is a common finding in urinary tract outflow obstruction. Chronically obstructed hydronephrotic system may be associated with parenchymal changes. Ultrasound, intravenous urography, micturating cysto-urethrogram and scintigraphy are commonly performed to evaluate the cause of obstruction. In childhood, ...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2015.05.003
更新日期:2015-11-01 00:00:00
abstract::We report a case of a patient with lung adenocarcinoma and bone and extraosseus metastases studied with (18)F-FDG PET-CT, (99m)Tc-HMDP and (18)F-fluoride PET-CT. It assesses the usefulness of (18)F-FDG PET-CT for initial staging of the disease and monitoring response to therapy. For the study of the sclerotic bone met...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2014.02.004
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Medullary carcinoma accounts for 1-2% of all thyroid malignancies. 13-20% of patients present with distant metastasis, with 45% of the cases affecting the liver. CLINICAL CASE:A 50-year-old woman, diagnosed with medullary thyroid carcinoma, was treated with total thyroidectomy and a modified neck dissecti...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2017.12.003
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:The routes of lymphatic drainage from a breast cancer are the axilla (the most frequent) and the extra axillary regions. Among the latter, there are the so-called intrammamary lymph nodes (IMLN). This study has aimed to assess the incidence of IMLNs in our patients and study the evolution of these cases with ...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2014.10.006
更新日期:2015-03-01 00:00:00
abstract::Early diagnosis and prompt treatment of acute osteomyelitis are of paramount importance in children because they can prevent irreversible bone damage. Magnetic resonance imaging (MRI) with its superior spatial resolution and lack of ionizing radiation is routinely preferred over bone scan for this purpose. Increased b...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2013.06.004
更新日期:2014-03-01 00:00:00
abstract::Moyamoya disease (MMD) is a cerebrovascular disorder involving stenosis of brain vessels. Brain perfusion SPECT in MMD demonstrates impaired perfusion in ischemic areas. We present a 6-year-old boy with MMD. The patient had numbness on the right arm and simultaneous electroencephalography changes while studying arms u...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2012.02.006
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:The central nervous system (CNS) may be involved in a variety of inflammatory diseases of the blood vessels, generally known as vasculitis. The clinical diagnosis of such involvement in early stages is difficult, since a mild cognitive impairment can be the only symptom. It was hypothesized that brain-perfusi...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2017.10.009
更新日期:2018-01-01 00:00:00
abstract::A 65-year-old male presented with unexplained hypoxia that became exacerbated by an upright posture (platypnea-orthodeoxia syndrome) secondary to hepatopulmonary syndrome (HPS). A (99m)Tc-macroaggregated albumin pulmonary perfusion scan revealed a right to left shunt of 29% in the sitting position, which had not been ...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2014.12.009
更新日期:2015-07-01 00:00:00
abstract::(99m)Tc-tetrofosmin single photon emission computed tomography ((99m)Tc-tetrofosmin SPECT) has an important role in the assessment of coronary artery disease. Despite being its main indication, this study does not only evaluate myocardial perfusion, but much more. Moreover, during the SPECT acquisition, the field area...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2015.03.005
更新日期:2015-11-01 00:00:00
abstract:INTRODUCTION:The goals of the study are to characterize imaging properties in 2D PET images reconstructed with the iterative algorithm ordered-subset expectation maximization (OSEM) and to propose a new method for the generation of synthetic images. MATERIAL AND METHODS:The noise is analyzed in terms of its magnitude,...
journal_title:Revista espanola de medicina nuclear e imagen molecular
pub_type: 杂志文章
doi:10.1016/j.remn.2017.10.007
更新日期:2018-01-01 00:00:00