Abstract:
OBJECTIVE:To examine the association between weight change from young adulthood to midlife and risk of incident arthritis. METHODS:Using data from the National Health and Nutrition Examination Survey (NHANES), we categorized participants into weight change categories based on their recalled weight during young adulthood and midlife. We estimated the association of weight change and developing an arthritis condition over 10 years using adjusted Cox models. Findings were extrapolated to the US population to determine the proportion of incident arthritis cases that could be averted if the entire population maintained a normal BMI in young adulthood and midlife. RESULTS:Among our sample of adults who were 40-69 years old at their midlife weight measure (n=13,669), 3,603 developed an arthritis condition. Compared with adults who maintained a normal-normal BMI, the normal-overweight, normal-obese, overweight-obese, and obese-obese groups had significantly elevated risk of incident arthritis conditions. The obese-overweight group had lower risk of incident arthritis conditions compared with the obese-obese group and comparable risk to the overweight-overweight group. Nearly one quarter of incident arthritis cases, corresponding to 2.7 million individuals, would have been averted under the hypothetical scenario where all individuals maintained normal weight from young adulthood to midlife. CONCLUSION:Weight loss from young adulthood to midlife was associated with substantially reduced risk of developing an arthritis condition. We found no evidence of residual risk from having been heavier earlier in life. Our findings highlight the critical need to expand obesity treatment and prevention to achieve meaningful reductions in the burden of arthritis.
journal_name
Arthritis Care Res (Hoboken)journal_title
Arthritis care & researchauthors
Berry KM,Neogi T,Baker JF,Collins JM,Waggoner JR,Hsiao CW,Johnston SS,LaValley MP,Stokes Adoi
10.1002/acr.24252subject
Has Abstractpub_date
2020-05-06 00:00:00eissn
2151-464Xissn
2151-4658pub_type
杂志文章abstract:OBJECTIVE:To examine the potential impact of a policy of selective referral to high-volume knee replacement hospitals on patients' travel distance to hospitals and access to care for patients seeking total knee replacement (TKR) in urban and rural settings. METHODS:The travel distance required for patients to reach th...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.21611
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:To develop and validate a short form of the Cochin Hand Function Scale (CHFS), which measures hand disability, for use in systemic sclerosis, using objective criteria and reproducible techniques. METHODS:Responses on the 18-item CHFS were obtained from English-speaking patients enrolled in the Scleroderma Pa...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22893
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:The Cohort Hip and Cohort Knee (CHECK) is a cohort of middle-aged individuals with hip or knee pain. Radiographs were assigned Kellgren & Lawrence (KL) scores under different conditions at each follow-up visit for 10 years. We aimed to describe and consolidate each scoring approach, then illustrate implicatio...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24563
更新日期:2021-01-15 00:00:00
abstract:OBJECTIVE:Cachexia is a disorder characterized by involuntary weight loss in addition to loss of homeostatic control of both energy and protein balance. Despite an abundance of data from other inflammatory diseases, cachexia in SLE remains a largely undescribed syndrome. METHODS:2406 patients in a prospective SLE coho...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24395
更新日期:2020-08-02 00:00:00
abstract:OBJECTIVE:Comorbidities add to the burden of disease and its complexity, and may prevent the achievement of treat-to-target goals. The objective of this study was to study the relationship between comorbidities and key disease outcomes in spondyloarthritis (SpA), namely function, work ability, and quality of life. MET...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.23468
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of severe fatigue and fatigue-related limitations among adolescents with juvenile idiopathic arthritis (JIA) and other pediatric rheumatic diseases (PRDs). In addition, we assessed the effect of disease activity and pain on the severity of fatigue. METHODS:This cross-sectional stu...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22710
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Although several individual nutrients/foods are associated with uric acid status, the association of overall diet quality with hyperuricemia remains unclear. We thus examined the association between adherence to the dietary approaches to stop hypertension (DASH) diet and odds of having hyperuricemia in a Chin...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24150
更新日期:2020-01-21 00:00:00
abstract:OBJECTIVE:Despite the joint pain and significant dysfunction that characterizes arthritis, many people with arthritis continue to carry out everyday duties and responsibilities. Our objective was to describe participation in informal caregiving (unpaid assistance to someone with a health issue or limitation) among peop...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24329
更新日期:2020-05-31 00:00:00
abstract:OBJECTIVE:We examined quality measures for screening, diagnosis, and treatment of lupus nephritis (LN) among participants of the California Lupus Epidemiology Study across 25 different clinical sites to identify gaps in quality of care. METHODS:Data from 250 participants with lupus were analyzed across 3 sources (medi...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23915
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To develop a clinical risk prediction tool to identify patients most likely to experience long-term clinically meaningful functional improvement following total hip arthroplasty (THA). METHODS:We studied 282 patients from 2 health districts in England (Portsmouth and North Staffordshire) who were ≥45 years o...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.21594
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:Up to 20% of people who undergo total knee replacement surgery have ongoing pain and discomfort. The aim of this study was to understand what role the concepts of embodiment (of both having a body and experiencing the world through one's body) and incorporation (integrating something into one's body) might ha...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24534
更新日期:2020-12-08 00:00:00
abstract:OBJECTIVE:A recent study conducted by our clinical group demonstrated that low disease activity (LDA), defined as a clinical Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) score ≤2, maintained for 12 months, confers the same risk for damage accrual as complete remission after 2 years. The aim of t...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23720
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:To examine cross-sectionally whether intraabdominal fat area (IAFA), i.e., visceral fat, and liver fat assessed by computed tomography (CT) are independently associated with hyperuricemia. METHODS:Subjects were 801 Japanese men not taking antidiabetic, antihypertensive, or urate-lowering medications, without...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22729
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:To clarify sex differences in early axial spondyloarthritis (SpA). METHODS:In total, 475 patients included in the Devenir des Spondylarthropathies Indifférenciées Récentes (Outcome of Recent Undifferentiated Spondylarthropathies) cohort, a prospective multicenter French cohort of patients with early inflamma...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.22001
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:Married persons have, on average, better mental health than nonmarried persons. Among married persons, marital satisfaction is associated with better mental health. Studies on mental health in married and nonmarried persons that consider marital satisfaction have categorized patients as satisfied versus unsat...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22802
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To identify a combination of clinical factors associated with low disease activity and remission in the third trimester during pregnancy in women with rheumatoid arthritis (RA). METHODS:This study is embedded in the Pregnancy-Induced Amelioration of Rheumatoid Arthritis study, a prospective cohort study. The...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23143
更新日期:2017-09-01 00:00:00
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journal_title:Arthritis care & research
pub_type: 杂志文章,评审
doi:10.1002/acr.24137
更新日期:2020-01-07 00:00:00
abstract:OBJECTIVE:To study the risk factors for revision of primary total hip replacement (THR) in a US population-based sample. METHODS:Using Medicare claims, we identified beneficiaries from 29 US states who underwent primary THR between July 1, 1995 and June 30, 1996, with followup through December 31, 2008. Potential case...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.21760
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:Methotrexate (MTX) is the anchor drug in the treatment of rheumatoid arthritis (RA) due to its effectiveness, tolerability, and cost. This study examines MTX prescribing practices in the US from 2009 to 2014. METHODS:Symphony Health Solutions, which covers 274 million patients in the US, was used to identify...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23152
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To examine trends in glucocorticoid (GC) use and dosing among patients diagnosed with rheumatoid arthritis (RA) over time. METHODS:A population-based inception cohort of RA patients diagnosed during 1980-2007 was followed longitudinally through their medical records until death, migration, or December 31, 20...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22365
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:Hallux valgus (HV) has been linked to functional disability and increased risk of falls, but mechanisms underpinning functional disability are unclear. This study investigated functional performance, muscle strength, and plantar pressures in adults with mild, moderate, and severe HV compared to controls, whil...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.22380
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:Children with juvenile idiopathic arthritis (JIA) experience functional impairment due to joint manifestations of the disease. The aim of our present study was to assess health-related quality of life (HRQOL) and its predictors in a group of children and adolescents with JIA. METHODS:The study sample include...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.21609
更新日期:2012-05-01 00:00:00
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journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/acr.22384
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the validity of different spondyloarthritis (SpA) features included in the Berlin diagnostic algorithm and the Assessment of SpondyloArthritis international Society (ASAS) classification criteria in an early SpA cohort. METHODS:This was a longitudinal multicenter study including patients from the...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
doi:10.1002/acr.23017
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To determine the extent to which demographic and geographic disparities exist in the use of post-acute rehabilitation care (PARC) for joint replacement. METHODS:We conducted a cross-sectional analysis of 2 years (2005 and 2006) of population-based hospital discharge data from 392 hospitals in 4 states (Arizo...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.20477
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:To examine patient willingness and a possible shift in willingness for surgery and to investigate factors associated with this shift, following participation in the digital nonsurgical osteoarthritis (OA) treatment program Joint Academy. METHODS:A total of 458 individuals (mean ± SD age 62 ± 5.6 years, 67% w...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.23772
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To determine the impact of stopping tumor necrosis factor inhibitor (TNFi) treatment on patient-reported outcomes (PROs) of physical and mental health status, health utility, pain, disability, and fatigue in patients with established rheumatoid arthritis (RA). METHODS:In the pragmatic, 12-month POET trial, 8...
journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/acr.23315
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of patient gender on patient-physician communication in the process of recommendation for total knee arthroplasty (TKA). METHODS:Seventy-one physicians (38 family physicians and 33 orthopedic surgeons) in Ontario performed blinded assessments of 2 standardized patients (1 man and 1 ...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.21970
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:To determine rates of cervical cancer screening and associated abnormal results in women with systemic lupus erythematosus (SLE). METHODS:We identified women with an initial diagnosis of SLE in the MarketScan Commercial Claims and Encounters Database from 2001 to 2014. Cervical cancer screening rates and ass...
journal_title:Arthritis care & research
pub_type: 杂志文章
doi:10.1002/acr.24414
更新日期:2020-08-16 00:00:00
abstract:OBJECTIVE:To validate manual muscle testing (MMT) for strength assessment in juvenile and adult dermatomyositis (DM) and polymyositis (PM). METHODS:Patients with PM/DM (73 children and 45 adults) were assessed at baseline and reevaluated 6-9 months later. We compared Total MMT (a group of 24 proximal, distal, and axia...
journal_title:Arthritis care & research
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/acr.20035
更新日期:2010-04-01 00:00:00