Electrotonic properties of neostriatal neurons are modulated by extracellular potassium.

Abstract:

:In order to assess the effects of [K+]o on the passive membrane properties of neostriatal neurons, the cable properties of these cells were determined at two extracellular potassium concentrations (6.25 and 3.0 mM). The effect of tetraethylammonium (TEA) on cable properties was also studied at 6.25 [K+]o. At 6.25 mM [K+]o, the mean input resistance at the resting membrane potential (RMP), and the mean membrane time constant (tau o) were 27 +/- 1.5 M omega and 6.9 +/- 0.5 ms respectively (n = 17), while at 3 mM [K+]o they were 62.9 +/- 4.8 M omega and 14.3 +/- 0.6 ms (n = 15) (mean +/- SEM). With one of the methods used to calculate the electronic parameters, the total electrotonic length of the dendrites (L) and the dendritic to somatic conductance ratio (rho) were 1.3 +/- 0.05 and 5 +/- 0.8 at the higher [K+]o respectively, while they were 0.95 +/- 0.04 and 3 +/- 0.7 at the lower [K+]o. Cells were depolarized in 6.25 as compared to 3 mM [K+]o (RMP = -66 +/- 1.3 mV vs RMP = -80.5 +/- 1.4 mV). After one hour exposure to TEA (10 mM), the input resistance and time constant tripled at 6.25 mM [K+]o. TEA slightly depolarized the cells bathed in 6.25 mM [K+]o. The results suggest that changes in [K+]o, within the physiological range, markedly affect the cable properties of neostriatal neurons, possibly modifying subthreshold, voltage-dependent K+-conductances. TEA seems to block some of these channels.

journal_name

Exp Brain Res

authors

Bargas J,Galarraga E,Aceves J

doi

10.1007/BF00250260

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

390-8

issue

2

eissn

0014-4819

issn

1432-1106

journal_volume

72

pub_type

杂志文章
  • Pattern of cortical reorganization in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study.

    abstract::Depending on individual lesion location and extent, reorganization of the human motor system has been observed with a high interindividual variability. In addition, variability of forces exerted, of motor effort, and of movement strategies complicates the interpretation of functional imaging studies. We hypothesize th...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-001-0981-9

    authors: Konrad C,Henningsen H,Bremer J,Mock B,Deppe M,Buchinger C,Turski P,Knecht S,Brooks B

    更新日期:2002-03-01 00:00:00

  • Calcitonin gene-related peptide-like immunoreactivity in motoneuron pools innervating different hind limb muscles in the rat.

    abstract::The content of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) in motoneurons was studied in four motor pools supplying muscles in the rat hind limb subserving different types of motor activity. The motor pools were identified by retrograde labeling with horseradish peroxidase or fluorophore-conjugated...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00227109

    authors: Piehl F,Arvidsson U,Hökfelt T,Cullheim S

    更新日期:1993-01-01 00:00:00

  • Anticipatory postural adjustments stabilise the whole upper-limb prior to a gentle index finger tap.

    abstract::Little is known about anticipatory postural adjustments (APAs) developing when body segments of tiny mass are moved. Thus, APAs in the human upper-limb were investigated during a gentle and small index finger tap (35 mm stroke in 50 ms). This task was fulfilled by ten subjects either with prone or supine hand. EMG was...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-008-1668-2

    authors: Caronni A,Cavallari P

    更新日期:2009-03-01 00:00:00

  • Trace eyeblink conditioning in human subjects with cerebellar lesions.

    abstract::Trace eyeblink conditioning was investigated in 31 patients with focal cerebellar lesions and 19 age-matched controls. Twelve patients presented with lesions including the territory of the superior cerebellar artery (SCA). In 19 patients lesions were restricted to the territory of the posterior inferior cerebellar art...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-005-0171-2

    authors: Gerwig M,Haerter K,Hajjar K,Dimitrova A,Maschke M,Kolb FP,Thilmann AF,Gizewski ER,Timmann D

    更新日期:2006-03-01 00:00:00

  • Critical periods in development for susceptibility to the effects of stroboscopic rearing in the rabbit visual cortex.

    abstract::Previous studies have shown that rearing rabbits in a stroboscopically illuminated environment results in a decrease in orientation and direction selectivity and an increase in responsivity to stroboscopic stimuli among neurons in area 17. In the present study, the critical period for susceptibility to these effects w...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00239202

    authors: Pearson HE,Berman N,Murphy EH

    更新日期:1983-01-01 00:00:00

  • Perception of affordances for standing on an inclined surface depends on height of center of mass.

    abstract::We investigated whether perception of affordances for standing on an inclined surface depended on the height of center of mass of the perceiver-actor. Participants adjusted the angle of inclination of a surface until they felt that it was just barely possible for them to stand on that surface. They performed this task...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-008-1492-8

    authors: Regia-Corte T,Wagman JB

    更新日期:2008-10-01 00:00:00

  • Cyclophosphamide cystitis as a model of visceral pain in rats. A survey of hindbrain structures involved in visceroception and nociception using the expression of c-Fos and Krox-24 proteins.

    abstract::The evoked expression of the immediate early gene-encoded proteins c-Fos and Krox-24 was used to study activation of hindbrain neurons as a function of the development of cyclophosphamide (CP) cystitis in behaving rats. CP-injected animals received a single dose of 100 mg/kg i.p. under transient volatile anesthesia an...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00227263

    authors: Bon K,Lantéri-Minet M,de Pommery J,Michiels JF,Menétrey D

    更新日期:1996-03-01 00:00:00

  • Negative priming for target selection with saccadic eye movements.

    abstract::We conducted a series of experiments to determine whether negative priming is used in the process of target selection for a saccadic eye movement. The key questions addressed the circumstances in which the negative priming of an object takes place, and the distinction between spatial and object-based effects. Experime...

    journal_title:Experimental brain research

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00221-012-3234-1

    authors: Donovan T,Crawford TJ,Litchfield D

    更新日期:2012-10-01 00:00:00

  • Can you hear shapes you touch?

    abstract::Shape is an inherent property of objects existing in both vision and touch but not audition. Can shape then be represented by sound artificially? It has previously been shown that sound can convey visual information by means of image-to-sound coding, but whether sound can code tactile information is not clear. Blindfo...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-010-2178-6

    authors: Kim JK,Zatorre RJ

    更新日期:2010-05-01 00:00:00

  • A projection from nucleus reticularis tegmenti pontis of Bechterew to the medial vestibular nucleus in rabbits.

    abstract::This study documents a bilateral projection from nucleus reticularis tegmenti pontis (NRTP) to the rostral aspect of the medial vestibular nucleus (MVN) in rabbits. Horseradish peroxidase injections in rostral MVN produced retrogradely labeled neurons in the caudal half of NRTP; caudal MVN injections produced negative...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00237207

    authors: Balaban CD

    更新日期:1983-01-01 00:00:00

  • Response interference in touch, vision, and crossmodally: beyond the spatial dimension.

    abstract::To date, tactile distractor processing has primarily been investigated by focusing on the spatial characteristics of distractors and the impact of their presentation on the orienting of attention. In two experiments, we examined the influence of tactile distractors when the location of stimulus presentation was kept c...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-014-3929-6

    authors: Mast F,Frings C,Spence C

    更新日期:2014-07-01 00:00:00

  • Sensory reweighting with translational visual stimuli in young and elderly adults: the role of state-dependent noise.

    abstract::The properties of sensory reweighting for control of human upright stance have primarily been investigated through experimental techniques such as sinusoidal driving of postural sway. However, other forms of visual inputs that are commonly encountered, such as translation, may produce different adaptive responses. We ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-006-0502-y

    authors: Jeka J,Allison L,Saffer M,Zhang Y,Carver S,Kiemel T

    更新日期:2006-10-01 00:00:00

  • Pyramidal cell specialization in the occipitotemporal cortex of the Chacma baboon (Papio ursinus).

    abstract::Pyramidal cell structure varies systematically in occipitotemporal visual areas in monkeys. The dendritic trees of pyramidal cells, on average, become larger, more branched and more spinous with progression from the primary visual area (V1) to the second visual area (V2), the fourth (V4, or dorsolateral DL visual area...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-005-0057-3

    authors: Elston GN,Benavides-Piccione R,Elston A,DeFelipe J,Manger P

    更新日期:2005-12-01 00:00:00

  • Behaviour of neurons in monkey peri-arcuate and precentral cortex before and during visually guided arm and hand movements.

    abstract::Neuron activity was recorded in monkey cerebral cortex during a visually guided reaching task. Cells located in the banks of the arcuate sulcus at its curvature changed their activity during the period in which the monkey saw a food reward in a certain position, but before it moved to retrieve the reward. A role of th...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00238755

    authors: Godschalk M,Lemon RN,Nijs HG,Kuypers HG

    更新日期:1981-01-01 00:00:00

  • Predictive strategies in interception tasks: differences between eye and hand movements.

    abstract::To investigate how the sensorimotor systems of eye and hand use position, velocity, and timing information of moving targets, we conducted a series of three experiments. Subjects performed combined eye-hand catch-up movements toward visual targets that moved with step-ramp-like velocity profiles. Visual feedback of th...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-004-2028-5

    authors: Eggert T,Rivas F,Straube A

    更新日期:2005-01-01 00:00:00

  • Increase in tibialis anterior motor cortex excitability following repetitive electrical stimulation of the common peroneal nerve.

    abstract::The purpose of this study was to investigate whether repetitive electrical stimulation of the common peroneal nerve (CPN) is associated with changes in the motor response of the tibialis anterior (TA) muscle elicited by focal magnetic stimulation of the motor cortex. Motor evoked potentials (MEP) with a stimulation in...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-002-1094-9

    authors: Khaslavskaia S,Ladouceur M,Sinkjaer T

    更新日期:2002-08-01 00:00:00

  • Corticobulbar and corticospinal projections to neck muscle motoneurons in man. A functional study with magnetic and electric transcranial brain stimulation.

    abstract::The cortical projections to neck muscle motoneurons were studied in normal subjects by electrical and magnetic transcranial brain stimulation. After magnetic stimulation with a large coil, motor evoked potentials were present in about 20% of relaxed and 100% of contracting neck muscles. The latency of these responses ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00231857

    authors: Berardelli A,Priori A,Inghilleri M,Cruccu G,Mercuri B,Manfredi M

    更新日期:1991-01-01 00:00:00

  • Impact of body posture on laterality judgement and explicit recognition tasks performed on self and others' hands.

    abstract::Judgments on laterality of hand stimuli are faster and more accurate when dealing with one's own than others' hand, i.e. the self-advantage. This advantage seems to be related to activation of a sensorimotor mechanism while implicitly processing one's own hands, but not during explicit one's own hand recognition. Here...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-015-4210-3

    authors: Conson M,Errico D,Mazzarella E,De Bellis F,Grossi D,Trojano L

    更新日期:2015-04-01 00:00:00

  • Association of spinal lamina I projections with brainstem catecholamine neurons in the monkey.

    abstract::In addition to giving primary projections to the parabrachial and periaqueductal gray regions, ascending lamina I projections course through and terminate in brainstem regions known to contain catecholaminergic cells. For this reason, double-labeling experiments were designed for analysis with light and electron micro...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00228547

    authors: Westlund KN,Craig AD

    更新日期:1996-07-01 00:00:00

  • Properties of a new vestibulospinal projection, the caudal vestibulospinal tract.

    abstract::Neurons in the caudal portions of the medial and descending vestibular nuclei and in vestibular cell group f that project to the cervical or lumbar spinal cord were located by antidromic spinal stimulation. These caudal vestibulospinal tract (CVST) neurons have a median conduction velocity of 12 m/sec, which is well b...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00239733

    authors: Peterson BW,Maunz RA,Fukushima K

    更新日期:1978-06-19 00:00:00

  • Characterization of L-glutamate uptake into and release from astrocytes and neurons cultured from different brain regions.

    abstract::The uptake of L-glutamate was studied in astrocytes cultured from different brain areas of newborn rats as well as in two different cultures of neurons obtained from mouse brain. Both astrocytes and neurons exhibited high-affinity glutamate uptake with Km values ranging from 34 microM to 82 microM. Vmax values for ast...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00239385

    authors: Drejer J,Larsson OM,Schousboe A

    更新日期:1982-01-01 00:00:00

  • Adaptive control of gait stability in reducing slip-related backward loss of balance.

    abstract::The properties of adaptation within the locomotor and balance control systems directed towards improving one's recovery strategy for fall prevention are not well understood. The purpose of this study was to examine adaptive control of gait stability to repeated slip exposure leading to a reduction in backward loss of ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-005-0189-5

    authors: Bhatt T,Wening JD,Pai YC

    更新日期:2006-03-01 00:00:00

  • Neuropeptide gene expression in brain is differentially regulated by midbrain dopamine neurons.

    abstract::In situ hybridization was used to study the expression of prepro-neuropeptide Y (NPY), preprosomatostatin (SOM), preprotachykinin (PPT) and preprocholecystokinin (CCK) mRNA in caudate-putamen and frontoparietal cortex of rat brain with unilateral lesion of midbrain dopamine neurons. Neurons expressing NPY and SOM mRNA...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00227990

    authors: Lindefors N,Brené S,Herrera-Marschitz M,Persson H

    更新日期:1990-01-01 00:00:00

  • Socioeconomic status and self-other processing: socioeconomic status predicts interference in the automatic imitation task.

    abstract::High-status individuals have been found to be less attuned to the behaviour of others in the social environment, at least in the absence of any specific instructions to pay attention to them. Previous work using neural measures has shown that socioeconomic status (SES) influences the degree to which people are attuned...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-020-05761-7

    authors: Farwaha S,Obhi SS

    更新日期:2020-04-01 00:00:00

  • Vestibular and somatosensory inflow to the vestibular projection area in the post cruciate dimple region of the cat cerebral cortex.

    abstract::In anesthetized cats 251 cells within the cortical vestibular projection area, adjacent to the post-cruciate dimple, were analyzed as to their input characteristics employing extracellular recording techniques. The post cruciate dimple vestibular field, which is located in area 3a, has a high degree of convergence bet...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00237688

    authors: Odkvist LM,Liedgreen SR,Larsby B,Jerlvall L

    更新日期:1975-01-01 00:00:00

  • Role of gravitational versus egocentric cues for human spatial orientation.

    abstract::Our perception of the vertical depends on allocentric information about the visual surrounds, egocentric information about the own body axis and gravicentric information about the pull of gravity. Previous work has documented that some individuals rely strongly on allocentric information, while others do not, and the ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-015-4526-z

    authors: Bury N,Bock O

    更新日期:2016-04-01 00:00:00

  • The inhibitory role of the visually responsive region of the thalamic reticular nucleus in the rat.

    abstract::Two-shock inhibition, a feature of 98 of 100 P cells recorded in the dorsal lateral geniculate nucleus of the normal rat, was not observed in 91 of 140 geniculate cells after an electrolytic lesion had been made in the adjacent visually responsive thalamic reticular nucleus. Nine geniculate cells recorded both before ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00237834

    authors: French CR,Sefton AJ,Mackay-Sim A

    更新日期:1985-01-01 00:00:00

  • Altered temporal profile of visual-auditory multisensory interactions in dyslexia.

    abstract::Recent studies have demonstrated that dyslexia is associated with deficits in the temporal encoding of sensory information. While most previous studies have focused on information processing within a single sensory modality, it is clear that the deficits seen in dyslexia span multiple sensory systems. Surprisingly, al...

    journal_title:Experimental brain research

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00221-005-2387-6

    authors: Hairston WD,Burdette JH,Flowers DL,Wood FB,Wallace MT

    更新日期:2005-10-01 00:00:00

  • Intensity dependent effect of cognitive training on motor cortical plasticity and cognitive performance in humans.

    abstract::Intervention-induced neuroplastic changes within the motor or cognitive system have been shown in the human brain. While cognitive and motor brain areas are densely interconnected, it is unclear whether this interconnectivity allows for a shared susceptibility to neuroplastic changes. Using the preparation for a theor...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-020-05933-5

    authors: Berns C,Brüchle W,Scho S,Schneefeld J,Schneider U,Rosenkranz K

    更新日期:2020-12-01 00:00:00

  • Structural aspects and physiological consequences of APP/APLP trans-dimerization.

    abstract::The amyloid precursor protein (APP) is one of the key proteins in Alzheimer's disease (AD), as it is the precursor of amyloid β (Aβ) peptides accumulating in amyloid plaques. The processing of APP and the pathogenic features of especially Aβ oligomers have been analyzed in detail. Remarkably, there is accumulating evi...

    journal_title:Experimental brain research

    pub_type: 杂志文章,评审

    doi:10.1007/s00221-011-2878-6

    authors: Baumkötter F,Wagner K,Eggert S,Wild K,Kins S

    更新日期:2012-04-01 00:00:00